JPS6311161A - Soft container - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

Detailed Description of the Invention ■ Background of the Invention (1) Technical Field This invention stores the solute stored in a solute storage chamber until immediately before use and the solvent stored in a solvent storage chamber separately, and mixes them immediately before use. This invention relates to a flexible container applied to a method of dissolution at the time of use.

(2) Prior art and its problems Conventionally, for example, in the medical field, the dissolution method at the time of use has been applied to the preparation of enteral nutritional solutions. The preparation of this enteral nutritional solution must be done in a clean place to avoid contamination with bacteria. Add nutrients and water (or ?!4) as needed and mix to adjust. However, since all of these preparations are carried out in an open system, it is difficult to maintain sterility during preparation, which often causes infectious diarrhea caused by bacteria.

Furthermore, no matter which preparation method is used, the number of bacteria is 2.
Under conditions of 0°C, it begins to increase significantly 6 hours after preparation, and becomes unusable after 24 hours, making it almost impossible to store it at room temperature after preparation. Therefore, special storage facilities are required.

Furthermore, reusing containers is time-consuming, as the containers must be thoroughly washed and dried after dispensing, and must be kept clean.

II. OBJECT OF THE INVENTION This invention has been made in view of the above-mentioned circumstances, and an object of the invention is to provide a flexible container that is a closed system and does not require special dispensing tools and can be dissolved at the time of use. It is to provide.

III. Structure of the Invention In order to achieve the above-mentioned object, a flexible container according to the present invention is a container made of a flexible material, the interior of which is divided into a first storage chamber and a second storage chamber by a partition wall. Generally, the partition wall is provided at one end of the container side edge side so that the seal can be released, and allows the stored items to flow only from the first storage chamber to the second storage chamber in the unsealed state. a first check valve, and a first check valve that is removably provided at the other end of the partition wall and that allows stored items to flow only from the second storage chamber to the first storage chamber in the unsealed state. It is characterized by having two reversal valves.

Further, according to the first embodiment of the present invention, the partition wall is provided in a suspended state at a predetermined angle with respect to the vertical direction, and the first check valve is connected to the second check valve. It is characterized by being located below the check valve.

Further, according to a second embodiment of the present invention, the first storage chamber is a solute storage chamber, and the second storage chamber is a solvent storage chamber.

Further, according to a third embodiment of the present invention, the solvent storage chamber is characterized in that a replenishment port for replenishing liquid is connected to the solvent storage chamber.

According to a fourth embodiment of the present invention, the solvent storage chamber is provided so that the seal can be released, and in the unsealed state, the solvent is allowed to flow out from the solvent storage chamber to the outside. It is characterized by being provided with a sealing body.

Further, according to a fifth embodiment of the present invention, the container body is made of soft plastic.

(1) Detailed Description and Function of the Invention Hereinafter, one embodiment of the flexible container according to the present invention will be described in detail with reference to the accompanying drawings.

As shown in FIG. 1, a flexible container (hereinafter referred to as a car bag) 10 of one embodiment is for dispensing, for example, an enteral nutritional solution by a dissolution method at the time of use, and has a substantially oblate elliptical shape. The bag body 11 is made of a soft synthetic resin such as vinyl chloride or EVA (ethylene vinyl acetate copolymer).

The inside of the bag body 11 is divided into a solute storage chamber 14 and a solvent storage chamber 16 by a partition wall 12. The solute storage chamber 14 stores a solute, and the solvent storage chamber 16 stores a powdered (or granular) enteral nutritional supplement. Note that the amounts of solute and solvent are determined so that the maximum concentration can be achieved during mixing. A hole 18 is formed in the center of one end of the bag body 11 on the solvent storage chamber 16 side, into which a hook (not shown) for suspending and holding the bag body 11 is inserted.

When a hook is inserted into this hole 18 and the bag 10 is suspended as shown in the figure, the solvent storage chamber 16 is positioned above the solute storage chamber 14, and the partition wall 12
extends so as to be inclined at a predetermined angle with respect to the horizontal direction. At the upper end of the partition wall 12 in the direction of inclination, a first check valve 20 that can be unsealed is provided to seal both chambers 14, 16. Further, at the lower end of the partition wall 12 in the inclination direction, there is a second check valve 22 that can be unsealed.
is provided with both N14 and 16 sealed.

As shown in FIG. 2A, each check valve 20, 22 is removably attached to a cylindrical body 24 and one end surface of this body 24 by breaking, and the check valves 20, 22 are detachably attached to the body 24 in the attached state. A cap 26 for sealing one end surface and a part of the main body 24 are attached to the other end surface so as to be removable, and when the cap 26 is removed, the main body 24 is attached as shown in FIG. 2B. A valve member 28 that opens the other end surface of the main body 24 when pressure is applied from inside, and closes the other end surface of the main body 24 when pressure is applied from outside the main body 24, as shown in FIG. 2C. It is composed of.

Here, the first check valve 20 is configured to allow only flow from the solute storage chamber 14 to the solvent storage chamber 16 when the cap 26 is removed and the seal is released. On the other hand, the second check valve 22 is configured to allow only flow from the solvent storage chamber 16 to the solute storage chamber 14 in an unsealed state.

In addition, as shown in FIG. 1, when the bag 10 is suspended, a solute storage chamber 14 is provided with a solute storage chamber 14 so that purified water for dilution can be injected therein as required. A mixed injection port 30 is connected. In addition, this mixed injection port 30
A take-out port 32 for taking out the prepared enteral nutritional solution is connected to the solute storage chamber 14 .

Further, this take-out port 32 is normally sealed with a cap 34, and this cap 34 is broken and removed at the time of take-out to release the seal and allow the take-out of the enteral nutritional solution. It is composed of

Regarding the bag 10 configured as above, 1.
A method for preparing an enteral nutritional solution by dissolving at the time of use will be explained.

First, prior to the dispensing operation, the bag 10 is heated so that the solute in the solute storage chamber 14 reaches a physiological temperature. After that, each cap 26 of the first and second check valves 20° 22 is broken with fingers and removed from the main body 24,
The sealing state between both chambers 14 and 16 is released.

In this unsealed state, first, as shown in FIGS. 3A and 3B, the solute storage chamber 1 of the bag body 11 is opened.
Press part 4 with your hand. This pressing causes the solution in the solute storage chamber 14 to be brought into the solvent storage chamber 16 via the first check valve 20 . In this way, first,
The solute and the solvent are mixed in the solvent storage chamber 16, and the solvent is mixed in 1. Dissolved in solute.

Note that since this first check valve 20 is attached to the upper end of the partition wall 12, the solute brought into the solvent storage chamber 16 via the first check valve 20 is transferred to the solvent storage chamber 16. It travels along the inner wall of the solvent storage chamber 16 and reaches every corner of the solvent storage chamber 16.

Next, as shown in FIGS. 4A and 4B, the solvent storage chamber 16 portion of the bag body 11 is pressed by hand. Due to this pressing, the solute/solvent solution in the solvent storage chamber 16 is
It is brought into the solute storage chamber 14 via the second check valve 22 . The solution mixed in advance in the solvent storage chamber 16 in this manner is sieved into the solute storage chamber 14, and the solvent is reliably dissolved in the solute.

Furthermore, since this second check valve 22 is attached to the lower end of the partition wall 12, the solution that has been sieved into the solute storage chamber 14 via the second check valve 22 is transferred to the solute storage chamber. The solute is distributed along the inner wall of the solute storage chamber 14 to every corner of the solute storage chamber 14, and concentration differences are substantially eliminated and homogenized.

Furthermore, by suspending the bag 10, the solution in the solvent storage chamber 16 is sifted into the solute storage chamber 14 by gravity, and all of the solution in the solvent storage chamber 16 does not remain here. It will be transferred into the solute storage chamber 14.

If the solvent is not completely dissolved in the solute during such an operation, the bag 10 is kneaded by hand to ensure complete dissolution.

Further, the solution is transferred again from the solute storage chamber 14 to the solvent storage chamber 16.
By repeating the operation of sending the solution to the solute storage chamber 14 and then returning it to the solute storage chamber 14, it is possible to reliably homogenize the solution.

In addition, the concentration of the prepared enteral nutritional solution is as follows:
This corresponds to the concentration set at the time of manufacturing, and this set concentration is the highest among the dosing conditions. Therefore, depending on the actual situation, the concentration may be diluted to change it to a desired concentration. In this case, purified water for dilution is mixedly poured from the mixing spout 30 to adjust the concentration to the desired concentration.

In this way, the prepared solution, that is, the enteral nutritional solution, is released by breaking the cab 34 of the outlet 32 with the bag 10 suspended, as shown in FIG. As a result, it is taken out from the take-out port 32.

As detailed above, according to this embodiment, by using this bag 10, the dispensing operation is performed in a closed system, so that a sterile state can be maintained until just before administration to the human body. . In addition, by simply removing the cap by breaking it, the seal between the two storage chambers is released, allowing the solute and solvent to mix.
Sterile preparation becomes possible.

In addition, if necessary, the enteral nutritional solution can be prepared immediately before administration, so that there is little change in the drug over time until immediately before administration, and it is possible to suppress the generation of bacteria after preparation.

Furthermore, since the solution and the solvent are mixed by the operator's hands, there is no need for a separate device exclusively for stirring, which saves time and effort.

Furthermore, since the sterile state is maintained both before and after dispensing, there is no need to rent dedicated storage facilities.

Furthermore, based on the above-mentioned effects, enteral nutrition, which had traditionally been performed mainly in hospitals, can now be performed safely and easily by the patient himself at home. This will be very convenient for both patients and doctors.

It goes without saying that this invention is not limited to the configuration of the one embodiment described above, and can be modified in various ways without departing from the gist of the invention.

■0 Specific Effects of the Invention As detailed above, the flexible container according to the present invention is made of a flexible material whose interior is divided into a first storage chamber and a second storage chamber by a partition wall. a container main body, and a releasable seal provided at one end of the container side edge of the partition wall, allowing the stored items to flow only from the first storage chamber to the second storage chamber in the unsealed state. a first check valve that is releasably provided at the other end of the partition wall, and allows the stored items to flow only from the second storage chamber to the first storage chamber in the unsealed state. The invention is characterized in that it includes a second check valve.

Therefore, according to the present invention, a flexible container is provided in which a dissolution method can be performed in a closed system without requiring special dispensing equipment.

[Brief explanation of the drawing]

FIG. 1 is a plan sectional view showing one embodiment of a flexible container according to the present invention, FIGS. 2A to 2C are side views showing the structure and operation of the reverse valve, and FIGS. Figure 3B is a cross-sectional plan view and side view, respectively, showing the first mixing operation of the solute and solvent. Figures 4A and N13 are a cross-sectional plan view and side view, respectively, showing the second mixing operation of the solute and solvent. , and FIG. 5 is a side sectional view showing the state when the prepared solution is taken out. In the figure, 10...Bag, 11...Bag body, 12
... Partition wall, 14 ... Solute storage chamber, 16 ... Solvent storage chamber, 18 ... Hole, 20 ... First check valve, 22.
... Second check valve, 24 ... Main body, 26 ... Cap, 28 ... Valve body, 30 ... Mixed injection port, 32 ... Output port, 34 ... Cap.

Claims (6)

[Claims] (1) A container body made of a flexible material whose interior is divided into a first storage chamber and a second storage chamber by a partition wall, and a container body provided at one end of the container side edge of the partition wall so as to be releasable. a first check valve that allows stored items to flow only from the first storage chamber to the second storage chamber in an unsealed state; and a first check valve that is removably provided at the other end of the partition wall and a second check valve that allows stored items to flow only from the second storage chamber to the first storage chamber in an unsealed state. (2) The partition wall is provided at a predetermined angle with respect to the vertical direction in a suspended state, and the first check valve is located below the second check valve. A flexible container as claimed in claim 1. (3) the first storage chamber is a solute storage chamber, and the second storage chamber is a solute storage chamber;
3. The flexible container according to claim 2, wherein the storage chamber is a solvent storage chamber. (4) The flexible container according to claim 3, wherein the solvent storage chamber is connected to a replenishment port for replenishing liquid. (5) The solvent storage chamber is provided so as to be unsealable;
The flexible flexible device according to claim 3 or 4, further comprising a sealing body that allows the solvent to flow out from the solvent storage chamber in an unsealed state. container. (6) The flexible container according to any one of the preceding claims, wherein the container body is made of soft plastic.