JPS63109870A - Blood treatment apparatus - Google Patents

Abstract

(57) [Abstract] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to an apparatus for circulating blood extracorporeally and removing components in the blood using a simple system.

(Prior Art and its Problems) Methods such as plasma separation and exchange systems, hemofiltration or dialysis systems that circulate blood extracorporeally and remove target substances from the blood through a filter membrane are conventionally known.

All of these systems require blood pumps, various monitors, and other peripheral equipment, and the overall configuration is complex, making it troublesome to set up a single circuit. Furthermore, during treatment, a shunt is usually surgically connected to the patient's blood vessel, which requires a lot of preparation work before the start of treatment.

For this reason, it is difficult to easily apply the above system to patients in emergencies or after surgery, or to donors for donor pheresis, and it has been desired to simplify the system.

The present invention has been provided in view of the current situation.

(Means for Solving the Problems) Therefore, the present invention provides a plasma separator in which a blood derivation circuit equipped with a blood pump and a plasma storage container are connected via a plasma derivation circuit, and a blood cell storage container equipped with a pressure detector. and a blood cell component return circuit provided with a stopcock, and provides a blood processing apparatus in which the blood pump and the stopcock are controlled in conjunction with the pressure detected by a pressure detector.

(Function) Open the stopcock 11, close the stopcock 19, and start the blood pump 4.
is driven to guide blood from the donor through the plasma derivation circuit 5 to the plasma separator 2, and store plasma components in the plasma reservoir 9.
The concentrated blood cell components are stored in the blood cell storage container 3 via the blood cell component return circuit 12. When a predetermined amount of blood cell components are stored and the pressure detector 15 reaches a predetermined pressure, the stop cock 11 is activated.
When the pump 4 is stopped by closing and opening 19, the concentrated blood cell components are returned to the blood donor via the concentrated blood cell component return circuit 18.

(Embodiment) The blood processing apparatus 1 of the present invention includes a plasma separator 2 and a pressure detector 15, in which a blood derivation circuit 5 provided with a blood pump 4 and a plasma storage stand 9 are connected via a plasma derivation circuit 10. It consists of an attached blood cell storage container 3 and a blood cell component return circuit 12.18 provided with a stopcock 11.19.

The blood cell storage container 3 is composed of an inner elastic container 13 and an outer hard or semi-hard container 14. A pressure detector 15 is connected to the container 14 via a tube 17.
3 communicates with the concentrated blood cell component return circuit 12.18.

21 is a sealed chamber formed between containers 13 and 14.

The drive of the blood pump 4 and the opening and closing of the stopcocks 11 and 19 are controlled in conjunction with each other as shown in Table 1 via the control device 20 based on a predetermined pressure detected by a pressure detector.

7 is a bottle containing an anticoagulant such as ACD liquid, and is connected to the blood extraction circuit 5 via an infusion line 6. An infusion pump 8 is attached in the middle of the infusion line 6.

The stopcock 11 is opened, the stopcock 19 is closed, the blood pump 4 is driven, and the donor's blood is guided to the plasma separator 2 via the shunt 23 and the blood introduction circuit 5. At this time, the infusion pump 7 is simultaneously driven to introduce the anticoagulant into the blood introduction circuit 5 to prevent blood coagulation.

The blood introduced into the plasma separator 2 is separated into a concentrated blood cell component and a plasma component as follows.

The plasma component passes through the separation membrane 22 and is stored in the plasma storage container 9 via the plasma conduction circuit 10.

On the other hand, the double thick blood cell component is sequentially stored into the elastic container 13 via the concentrated blood cell component return circuit 12.

As the concentrated blood cells accumulate in the volume 1i% 13, they gradually expand and compress the sealed chamber 21, so that the pressure of the pressure detector 15 increases and approaches the predetermined pressure that has been set.

When the predetermined value is reached, the control device is activated and the blood pump 4 becomes [
I: Stop cock 11 is closed and stop cock 19 is open.

The concentrated blood cell components in the container 13 are returned to the blood donor via a return circuit 18 and a shunt 23.

As the number of blood cells in the container 13 decreases, it gradually contracts and the pressure in the sealed chamber 21 decreases, and when the blood cells are completely returned, the pressure in the pressure detector 15 becomes the lowest. The control device 20 is activated again, the stopcock 19 is closed, the blood pump is started, the stopcock 11 is opened, and the blood enters the plasma shunt device 2 via the blood outlet circuit 5 again, and the plasma passes through the membrane 22. The blood passes through the plasma derivation circuit 10 and is stored in a storage container 9, while the concentrated self-spheres pass through a blood cell component return circuit 12 and are stored in a container 13.

At this time, the pressure changes only by moving between the set pressure and the minimum pressure as shown in FIG.

Table 1 (Effects of the invention) As explained above, in the present invention, the separation of plasma components and the return of blood cell components can be performed automatically by simply setting the initial pressure, so blood collection and blood return can be performed software. Therefore, there are no problems such as hemolysis, and the operation is simple.

[Brief explanation of the drawing]

FIG. 1 is a schematic diagram of a system showing an embodiment of the present invention, and FIG. 2 is a state diagram showing pressure fluctuations during operation of the blood processing apparatus of the present invention. In the figure, l is a blood processing device, 2 is a plasma separator, 3 is a blood cell storage container, 4 is a blood pump, 5 is a blood extraction circuit, 9 is a plasma storage container, 11.19 is a stopcock, 12.18 is a The blood cell component return circuit 15 is a pressure detector, and 20 is a control device.

Claims (1)

[Scope of Claims] A blood processing device that circulates blood extracorporeally, separates and collects plasma components in the blood, and returns concentrated blood cell components to the body, comprising a blood extraction circuit equipped with a blood pump and a plasma storage container. It consists of a plasma separator connected via a plasma derivation circuit, a blood cell storage container equipped with a pressure detector, and a blood cell component return circuit equipped with a stopcock, and the blood pump and stopcock are detected by the pressure detector. A blood processing device characterized by interlocking control based on pressure.