JPS63104908A - Chewing gum for preventing teeth decay - Google Patents
Chewing gum for preventing teeth decayInfo
- Publication number
- JPS63104908A JPS63104908A JP25029586A JP25029586A JPS63104908A JP S63104908 A JPS63104908 A JP S63104908A JP 25029586 A JP25029586 A JP 25029586A JP 25029586 A JP25029586 A JP 25029586A JP S63104908 A JPS63104908 A JP S63104908A
- Authority
- JP
- Japan
- Prior art keywords
- chewing gum
- glucoamylase
- amylase
- teeth
- decay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229940112822 chewing gum Drugs 0.000 title abstract description 10
- 235000015218 chewing gum Nutrition 0.000 title abstract description 10
- 230000003405 preventing effect Effects 0.000 title abstract description 5
- 239000004382 Amylase Substances 0.000 claims abstract description 13
- 108010065511 Amylases Proteins 0.000 claims abstract description 13
- 102000013142 Amylases Human genes 0.000 claims abstract description 13
- 235000019418 amylase Nutrition 0.000 claims abstract description 13
- 108010073178 Glucan 1,4-alpha-Glucosidase Proteins 0.000 claims abstract description 11
- 102100022624 Glucoamylase Human genes 0.000 claims abstract description 11
- 208000002925 dental caries Diseases 0.000 claims abstract description 6
- 208000006558 Dental Calculus Diseases 0.000 abstract description 9
- 102000004190 Enzymes Human genes 0.000 abstract description 5
- 108090000790 Enzymes Proteins 0.000 abstract description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 4
- 230000000694 effects Effects 0.000 abstract description 4
- 239000008103 glucose Substances 0.000 abstract description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract description 2
- 239000003963 antioxidant agent Substances 0.000 abstract description 2
- 235000013599 spices Nutrition 0.000 abstract description 2
- 239000002562 thickening agent Substances 0.000 abstract description 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 2
- 206010044029 Tooth deposit Diseases 0.000 abstract 1
- 230000002421 anti-septic effect Effects 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000008021 deposition Effects 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 235000020429 malt syrup Nutrition 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 description 6
- 235000019698 starch Nutrition 0.000 description 6
- 239000008107 starch Substances 0.000 description 5
- 229940088598 enzyme Drugs 0.000 description 4
- 241000209140 Triticum Species 0.000 description 3
- 235000021307 Triticum Nutrition 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 208000014151 Stomatognathic disease Diseases 0.000 description 2
- 244000299461 Theobroma cacao Species 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 108090000637 alpha-Amylases Proteins 0.000 description 2
- 102000004139 alpha-Amylases Human genes 0.000 description 2
- 229940024171 alpha-amylase Drugs 0.000 description 2
- 230000001680 brushing effect Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 206010006326 Breath odour Diseases 0.000 description 1
- 240000005979 Hordeum vulgare Species 0.000 description 1
- 235000007340 Hordeum vulgare Nutrition 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 108010019077 beta-Amylase Proteins 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 239000000417 fungicide Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 235000015094 jam Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 235000020712 soy bean extract Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 229940034610 toothpaste Drugs 0.000 description 1
- 239000000606 toothpaste Substances 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は、アミラーゼ及び／又はグルコアミラーゼをガ
ムの成分として配合することを特徴とし、歯の表面にた
まっている含水炭素（砂糖、米、麦、いも類等）に強力
に作用させて、ブドウ糖、アルコールに分解させ、むし
歯を予防する効果を付与する新規なむし歯予防のガムを
提供するものである。Detailed Description of the Invention [Industrial Application Field] The present invention is characterized by incorporating amylase and/or glucoamylase as a component of the gum, and is characterized by the fact that amylase and/or glucoamylase are blended as a component of the gum. The present invention provides a novel caries-preventing gum that strongly acts on wheat (wheat, potatoes, etc.) to decompose it into glucose and alcohol, thereby imparting a caries-preventing effect.
食物にはむし歯を発生しやすいものがあり、この中には
、砂糖性、澱粉性で歯に付着しやすいビスケット、ジャ
ム、チョコレート、蜂蜜、ココア等子供が好きなものが
多い。われわれが飲食物をとる限り、それが歯につき、
しかも口は温度や湿度が適当に保たれ、無数の微生物に
より汚染され、口臭をともなう。また歯の表面には歯垢
や歯石が沈着し、歯の病気を発生する原因となる。There are foods that can easily cause cavities, and many of these foods are sugar-based, starchy-based foods that children like, such as biscuits, jam, chocolate, honey, and cocoa, which tend to stick to the teeth. As long as we eat and drink, it sticks to our teeth.
Moreover, the mouth is kept at an appropriate temperature and humidity, and is contaminated by countless microorganisms, resulting in bad breath. Furthermore, plaque and tartar are deposited on the surface of teeth, causing dental diseases.
したがって歯を清掃することは、口の中を清潔にし、歯
の病気を予防することにつながる。歯を清掃する場合、
いちばんよく使用されているのは歯ブラシと歯磨である
が、この方法は、歯肉をそこない悪い結果につながるこ
とも多く、又、忙しい毎日、朝夕、磨くだけで、日昼の
大切な時間帯のほとんどがないがしろにされている。又
、子供は歯磨をきらうこと場合が多く、その代りに、親
がチューインガムをかませる等の対策を取るが、この中
には沢山の糖等を含んでいるので、むし歯になるのを益
々加速しているきらいがある。Therefore, cleaning your teeth helps keep your mouth clean and prevents dental diseases. When cleaning your teeth,
The most commonly used method is a toothbrush and toothpaste, but this method often damages the gums and leads to bad results.Also, simply brushing in the morning and evening during busy days can save you time during the important hours of the day and afternoon. Most are neglected. In addition, children often dislike brushing their teeth, and instead, parents take measures such as giving them chewing gum, but this contains a lot of sugar, which further accelerates the development of cavities. I hate doing that.
本発明者らは上記事情にかんがみ、むし歯予防に有効な
方法を得るべく鋭意研究をかさねた結果、アミラーゼ及
び／又はグルコアミラーゼに注目し、これをチューイン
ガムに配合することにより、この課題を解決しうろこと
を見いだし、本発明を完成するに至った。In view of the above circumstances, the present inventors have conducted extensive research to find an effective method for preventing dental caries. As a result, they focused on amylase and/or glucoamylase, and solved this problem by incorporating this into chewing gum. They discovered scales and completed the present invention.
〔問題点を解決するための手段および作用〕すなわち、
本発明は、アミラーゼ及び／又はグルコアミラーゼを含
有することを特徴とするむし歯予防のガムである。[Means and actions for solving the problem] That is,
The present invention is a caries-preventing gum characterized by containing amylase and/or glucoamylase.
本発明に用いられるアミラーゼ、グルコアミラーゼは広
く生物界に分布するものである。例えば、α−アミラー
ゼとしては、ヒト唾液、ブタ膵臓、カビ（タカ・アミラ
ーゼ）、細菌（Ｂ、５ｕｂｔｉ Ｉｉｓなど）から結晶
化されるものである。又、β−アミラーゼとしては、大
麦、小麦、サツマイモ、ダイズ抽出液などから分離され
たものが挙げられる。Amylase and glucoamylase used in the present invention are widely distributed in the living world. For example, α-amylase is crystallized from human saliva, porcine pancreas, fungi (Taka amylase), bacteria (B, 5ubti Iis, etc.). Examples of β-amylase include those isolated from barley, wheat, sweet potato, soybean extracts, and the like.
グルコアミラーゼは、デンプンを末端からグルコース単
位で分解する酵素で、カビ（Ａｓｐｅｒｇｉｌｌｕｓｎ
ｉｇｅｒ、Ｒｈｙｚｏｐｕｓ属など）、細菌、酵母など
に存在し、現在デンプンからのグルコースの工業的生産
に用いられているものである。Glucoamylase is an enzyme that breaks down starch into glucose units from the terminal end, and is
iger, Rhyzopus genus, etc.), bacteria, yeast, etc., and is currently used in the industrial production of glucose from starch.
市販品としては、例えば、ダイキン工業側製のダビアー
ゼに−２７がある。ダビアーゼに−２７は、Ａｓｐｅｒ
ｇｉｌｌｕｓ 属の一種のカビが産生ずるアミラーゼで
、通常のアミラーゼと同様に糊化澱粉に作用すると同時
に、各種生澱粉に強力に作用しブドウ糖を生成する。本
酵素は、α−アミラーゼとグルコアミラーゼの混合物で
両酵素の共存で生澱粉を分解する。As a commercially available product, there is, for example, Daviase -27 manufactured by Daikin Industries. Daviase-27 is Asper
Amylase is produced by a type of fungus in the genus Gillus, and it acts on gelatinized starch like normal amylase, and at the same time acts strongly on various raw starches to produce glucose. This enzyme is a mixture of α-amylase and glucoamylase, and the coexistence of both enzymes decomposes raw starch.
さらに阪急共栄物産■製のりゾパース起源のアミラーゼ
で商標名グルターゼも好適に使用し得る。Furthermore, amylase derived from Norizopers manufactured by Hankyu Kyoei Bussan (trade name: Glutase) may also be suitably used.
本発明のアミラーゼ及び／又はグルコアミラーゼを含有
するむし歯予防のガムは、酵素以外に、本発明の効果を
損なわない範囲内で必要により、チューインガムのタイ
プに応じて、各種ガム質ベース、各種糖、水飴、香料、
増粘剤、酸化防止剤、防腐防黴剤、色素等、通常チュー
インガムの製造に用いられる成分を配合することができ
る。The gum for preventing cavities containing amylase and/or glucoamylase of the present invention may contain, in addition to enzymes, various gum bases, various sugars, etc., depending on the type of chewing gum, as necessary, within a range that does not impair the effects of the present invention. starch syrup, spices,
Ingredients normally used in the production of chewing gum, such as thickeners, antioxidants, preservatives and fungicides, and pigments, can be blended.
つぎに実施例および比較例をあげて、本発明を具体的に
明らかにする。本発明はこれにより限定されるものでは
ない。Next, Examples and Comparative Examples will be given to specifically clarify the present invention. The present invention is not limited thereby.
表−１
歯石を除去したパネル１０名に、６力月間、毎日少なく
とも１回、実施例のガムを使用させたところ、いずれも
歯石の蓄積が著しく抑制された。Table 1 When 10 panelists who had removed tartar used the gum of the example at least once a day for six months, the accumulation of tartar was significantly suppressed in all cases.
これに対し、ダビアーゼに−２７を配合していない比較
例のガムを用いた１０名では、効果が認められず、歯石
の蓄積が見られた。On the other hand, in 10 people who used the gum of the comparative example in which -27 was not blended with dabiase, no effect was observed and accumulation of tartar was observed.
結果を表−２に示す。The results are shown in Table-2.
判定基準 ◎；全全部歯茎の周囲に歯垢、歯石が見られない。Judgment criteria ◎: No plaque or tartar was seen around the gums in all cases.
Ｏ；一部の歯茎の周囲に歯垢、歯石が見られる。O: Plaque and tartar are seen around some gums.
Δ；約半分の歯茎の周囲に歯垢、歯石が見られる。Δ: Plaque and tartar are seen around half of the gums.
×；はとんど全部の歯茎の周囲に歯垢、歯石が見られる
。×: Plaque and tartar are seen around almost all the gums.
表−２Table-2
Claims (1)
を特徴とするむし歯予防のガム。A caries-preventing gum characterized by containing amylase and/or glucoamylase.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25029586A JPS63104908A (en) | 1986-10-21 | 1986-10-21 | Chewing gum for preventing teeth decay |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25029586A JPS63104908A (en) | 1986-10-21 | 1986-10-21 | Chewing gum for preventing teeth decay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS63104908A true JPS63104908A (en) | 1988-05-10 |
Family
ID=17205779
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP25029586A Pending JPS63104908A (en) | 1986-10-21 | 1986-10-21 | Chewing gum for preventing teeth decay |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63104908A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413501B2 (en) | 1997-10-17 | 2002-07-02 | Novozymes A/S | Plaque-inhibiting oral compositions |
| WO2005006872A1 (en) | 2003-07-11 | 2005-01-27 | Colgate-Palmolive Company | Chewable antiplaque confectionery dental composition |
-
1986
- 1986-10-21 JP JP25029586A patent/JPS63104908A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6413501B2 (en) | 1997-10-17 | 2002-07-02 | Novozymes A/S | Plaque-inhibiting oral compositions |
| WO2005006872A1 (en) | 2003-07-11 | 2005-01-27 | Colgate-Palmolive Company | Chewable antiplaque confectionery dental composition |
| US7354569B2 (en) | 2003-07-11 | 2008-04-08 | Colgate-Palmolive Company | Chewable antiplaque confectionery dental composition |
| US8524197B2 (en) | 2003-07-11 | 2013-09-03 | Colgate-Palmolive Company | Chewable antiplaque confectionery dental composition |
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