JPS6291447A - Cement composition - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a cement two-blade one-component which is cemented and is characterized by not collapsing or falling off.

Conventional Technique 1: Not only surgery but also surgery in the cavity or mF・Fiil region.
Cement D agents of various weights have traditionally been used as wound dressings in plastic surgery and cardiac medicine, and are commercially available. Most of these use zinc oxide and euzonol as basic materials,
Asbestos fibers are used as reinforcing agents for the cement. Asbestos fibers are said to have a good compatibility with modified zinc and euzonol, and are said to have the effect of suppressing the stickiness of these materials when subjected to the freezing phase force.There are commercially available products that utilize this property. It has been formulated.

Intraoral 1-view n1x surgery is routinely performed in the fields of plastic surgery, oral surgery, and dentistry. For example, in plastic surgery, surgery for malformations of the mouth, in oral surgery, removal of intracavitary tumor cords, surgery that reaches the jawbone, and in occlusal medicine, I
Includes l#+lmi surgery, gingivectomy, tooth (i removal, tooth extraction, etc.).

Due to its daily functions, the oral cavity is always wet with saliva.
It is an organ that chews food and has conversations, and its thin stomach, which has many ridges and is known to be a rabbit, has a normal pressure. After surgery in such areas, 19 ri should be removed! ! In some cases, the wound may be compressed with a cotton ball like the wound surface of a sickle, and it may heal naturally.
Apply a disinfectant such as iodine to the wound surface after removing tartar. In some cases, people who are in a rut may be sent home. However, when the wound surface is large and deep, and when the primary objective is to recover from normal life, a special cement that hardens in the oral cavity is often used.

When applied, this cement is as soft and plastic as viscous L, and the hardening reaction is accelerated by moisture and 77 rA degrees within the first cavity, and it hardens in a few minutes, wrapping the wound surface.

This cement is called pack shavings or bandage.

The pack is made up of a combination of wood and a liquid agent, the powder mainly consisting of zinc oxide, and the liquid agent being a type of so-called zinc oxide eugenol cement mainly consisting of eunonol (eudanol). Of those 9! [This is because the asbestos fiber is formulated as a powder, and the fiber is an ingredient that cannot be handled in all steps from kneading to application, and the cement is hardened. It has the role of a ``tether'' that connects the substance of the cement, and maintains its toughness in the oral cavity so that it will not break until the open wound has healed.

Of the above-mentioned roles of asbestos fibers, which are to provide operability and toughness, the latter is achieved by other fibers such as cotton, nylon, etc. Although spring iron, acrylic, etc. can be used as substitutes to some extent, the operability of the former requires a delicate feel, which was conventionally thought to be achieved only with asbestos.

To explain the operability, the operator first takes an appropriate amount of the powder and liquid, mixes it with a spoon, makes yeast, and mixes the paste with the paste. Roll it with a chula, push it off the coast and make a diameter! fin. Shape into a cylinder with a length of about 4tcm. If asbestos is not mixed in this operation, the paste will not become cylindrical, and the paste will be
It is difficult to handle as it sticks to the tumbler or plywood board. Next, the surgeon picks up the cylindrical mixture with his fingers, applies it to the +JI 1M surface in the oral cavity, and spreads it flat with his fingertips to completely cover the wound surface. If the mixture sticks to the hand J1 when the operator handles the mixture with his fingers, it is difficult to apply the mixture to the wound surface. It is known that a dressing that is easy for the operator to use, that is, has good operability, can be achieved by combining asbestos, and fibers other than asbestos cannot provide this operability. It has been said that

However, in recent years, it has become a problem that asbestos has an adverse effect on the human body, and there is therefore a demand for an alternative to it. Improvement in long-term local retention is required.

Means for Solving the Problems According to the present invention, in view of the above points, in order to obtain an improved cement composition, asbestos in the conventional cement composition is substituted and mixed with No. Furthermore, carboxyvinyl $ IJ -r - (hereinafter abbreviated as CVP) is mixed. The novel cement composition obtained in this manner easily adheres to the gums or tooth structure, has a longer local retention than before, is resistant to falling off or disintegrating, and is easy to manufacture. Due to its low cost, it is ideal as a dressing for tissue and wound surfaces.

The characteristics of the present invention are that the conventionally known zinc oxide, eugenol, asbestos fibers, and organic saturated Ha fatty acids are mixed with pulp fibers in place of asbestos fibers in a cement composition composed of organic unsaturated fatty acids; Furthermore, CVP is used to improve adhesion to soft tissues and tooth surfaces or wound surfaces, early shedding after application, and disintegration of cement parenchyma.
It consists in mixing. When a cement composition made of gi-lead oxide and eugenol made without adding asbestos is used as a wound dressing, the mixture sticks to the hands and fingers, so it is difficult to apply the mixture on the palm of the hand. It has disadvantages such as the difficulty of rounding it up.

In the present invention, the agent consists of an agent mainly containing zinc oxide and an agent B containing eugenol or an organic acid, and when used, the agent and agent 8 are appropriately mixed and applied to the affected area, but the fiber is usually included in agent A. Since it is prescribed, we first examined autopsy in the present invention. As a result, when asbestos is mixed in place of the conventional asbestos in the cement composition, the strength of the hardened cement product (hereinafter abbreviated as cement body) is improved. The adhesion of the cement body to the tissue or gingival surface has been improved, and the shedding and disintegration of the cement body have been significantly improved, making it possible to use it for a long period of time.

In this case, nylon, vinylon, or tetron fibers were used as oil fibers in place of pulp fibers, but they could not achieve the same effect as 4-Ruso fibers. This is 4
Luso fibers are produced by cutting cotton fibers, and include free 10H groups and -
O Due to the presence of wood-philic groups such as HO groups, the fibers have an affinity for the B agent and at the same time exhibit the physical protective properties of the fibers for the B agent, so these properties affect the toughness of the cement mix. We believe that this contributes to the property of securing the adhesive and not sticking to the surgeon's fingers.

On the other hand, as mentioned above, CVP is a water-soluble polymer obtained by copolymerizing acrylic acid and allylated polyalcohol, and has been known as a thickener or dispersion stabilizer for cosmetics and pharmaceuticals. [However, there have been no examples of its use in dental cement compositions prior to the present invention. For example, it was not as effective as water-soluble polymer and VP. This is because CVP acts as a strong surfactant in the cement composition due to the presence of OH and COOH groups in the molecule, thus increasing the affinity of the composition for each other and encounter with saliva.
As a result of increasing the viscosity of the surface of the cement body and improving its affinity with living tissue, the adhesion to the surface of the group 1 or tooth substance or gingival surface increases, and in interaction with the action of the 4-4 fibers, the cement It is thought that it improves the characteristics of the body.

Furthermore, as a result of 4 studies on substances that can be substituted for CVP, 4 organic fatty acids such as lumitic acid and stearic acid are substituted for CVP.
It was found that the effect was similar to that of P. In the present invention, C
The organic fatty acids in the hemolymph as a substitute for VP or used in combination with Cvp are lauric acid, myristic acid, nolactic acid, and stearic acid, which are solid fatty acids at room temperature. These organic fatty acids have -COOHA in their molecules, which is common to cyp, which has a 1000H group in its molecules. -CH2- of the ray fatty acid is hydrophobic, but the -COOH group is hydrophilic, and as a result, in order to increase the affinity between the cement surface and living tissue, similar to the use of CVP. It is believed that this improves the properties of the cement body.

In addition, pulp fibers are included in the A agent of the cement composition.
It is preferable that the cement composition is sewn with 7 layers of plain stitches, and CVP and/or organic fatty acids are included in the agent of the cement composition.
Preferably, they are mixed in an amount of t% by weight.

Next, regarding agent B, this is Eugenol and Ori! consisting of oil, eugenol jθ~7 j−1i ti%,
The appropriate amount of olive oil is 20 to 70% by weight, and organic fatty acids have a carbon number of 10 to 2.2 and are generally 2〇nH2n+IC.
0OHr Cn'zn-ICOOH, CnH2n-gc
It is an organic saturated or unsaturated fatty acid corresponding to either OOH or CnH2n 5 C0OH, and propylene glycol and polyalkylene glycol can also be used as the B subcomponent. Additionally, mixtures of these dalicol compounds may also be used.

Eugenol (oil-nol) is the main component of clove oil (usually containing 70% or more), but Japanese Pharmacopoeia clove oil contains eugenol and related compounds as a total oil-nol.
θ% or more is considered as a standard for inclusion of seams. In the present invention, eugenol is considered to be almost the same substance as the above-mentioned pharmacopoeia clove oil, and the product of the present invention can be manufactured.

The specific components of the cement composition of the present invention have been described in detail above, but as shown in the examples, the cement composition is manufactured by first weighing the charged amount of each component of the agent, pulverizing it, and then mixing it with a stirrer. It is manufactured after being made into approximately one batch of mixed phase material (powder). For B shaving, B #11 is weighed and mixed in the state office [it is sufficient if the whole (liquid) is uniform.When using, the operator takes an appropriate amount of agent ^ and agent B, and freezes it. Use at the same time on the affected area.

Ichikyo - Houkisei Ichika - J (＾ Agent) (Heavy It%) (8 agents) (41%) Zinc oxide 5! r T letter oil 7! rRozone KoS Oryzo oil KoIA3 diatomaceous earth
/S Zorobio/Acid aS arm Lua ° & a male
1 CVP/Rosin lump is pre-pulverized to 10 mesh steps, and this crushed rosin is obtained. A mixture of 25 tons and 5 tons of zinc oxide was mixed and pulverized.

Keitsuku earth/! against the crushing and snout! To 9, # was added to I Lua Q fiber pb and cVP/ and mixed at a slow speed to prepare a preparation. As for agent B, T-shaped oil 7j, ori! Weigh out 5 kg of oil for 2 people and 8' y of propionic acid and mix them to make 8
A drug was prepared.

The product of this example can be suitably used not only in dentistry and oral surgery, but also in surgery, plastic surgery, veterinary medicine, and the like.

-Example λ (＾ agent) (heavy welfare%) (B agent) (,X
￥Jk%) Zinc oxide 60 T-shaped oil AS Lozone -Left Oryzo oil 3
A pulverized product was prepared by mixing 6θ kg of zinc oxide and 25 kg of rosin according to Example 7 of Lua #Fiber on the left, and 7 g of magnesium stearate, 7 g of magnesium stearate, and 7 g of magnesium stearate. cvPQ2k
g was added to prepare a ^ agent.

As for B, agent B was prepared by mixing 1 kg of T-shaped oil and 35 kg of Oryzo oil according to the method in Example/.

Example 22 (A agent) (weight; 10 (B shaved) (Actual 1 day lead oxide left N Eugenol Otsu θ Lozone
3θ Olive oil lIO diatomaceous earth
/ θ ) 9 Luso fibers Dastearic acid / Example / Zinc oxide &,! rkg and rosin 30 to 9
A pulverized product is prepared by mixing the
kg, Parf fiber lIV and stearic acid/yu were added to prepare a gelatin. For agent B, 6θ kg of eugenol and θkfl of olive oil were mixed to prepare agent B according to the method in Example.

Example Da (＾ agent) (wound 0) (day agent) (1%) zinc oxide
! f & linole e, 20μ thin
20 Isostearic acid 30 years ago Rude fiber lA left CVP O,! According to Example/, a pulverized product was prepared by mixing 20 kg of oxidized salivary lead S and rosin, and to this, diatomaceous earth -〇kg, pulp fiber G S and CVPθ were added to prepare a pulverized product. . For 8 cuts, follow the method in Example/ linoleic acid aθkg
, 30 kl of isostearic acid and θ kg of propylene glycol were mixed to prepare Form B.

Example, 9 (A agent) ltkt%) (B agent) (ff
iii1%) Zinc oxide lIO linoleic acid
Left 0 Pal 7″ fiber m Left CVP 3 According to Example/, a pulverized product was prepared by mixing 110 kg of zinc oxide resin and rosin, and to this, diatomaceous earth/, 2#s
Nor+Ruso fiber Skg and cvp 3v were added to prepare a ^ agent. As for the B agent, linoleic acid (OH) and zoropylene glycol (sokg) were weighed out and mixed to prepare a B agent.

Example (A agent) (U%) (A agent B) (wt 1%) Zinc oxide Eugenol 6S Rozone
, 2g oryzo oil 3'A! f diatomaceous earth /S zolopionic acid o, S pulp 1 male
Left CVP / qlistic acid / Zinc oxide according to Example 1! A pulverized product was prepared by mixing θkg and rosin 2gkl/, and diatomaceous earth/! to 4
1, /f yv ′:j′m fiber gkg, c v P
/to? A preparation was prepared by adding listic acid.

For agent B, Eugenol 63, Oryzo oil 3'ASJ, and Noropionic acid θ were mixed to prepare agent B according to the method in column 1.

The ＾ shavings (powder) and B produced in each example above the effect of the invention
The mixture obtained by kneading an appropriate number of agents (liquid agents) easily adheres not only to the oral cavity but also to wet wound surfaces in other fields such as surgery, plastic surgery, veterinary medicine, etc. It is expected that by stably staying locally in the fijlJ region for a long period of time, it will be sufficiently effective in protecting the *'s'J'Qk surface.

Furthermore, since the composition of this preparation does not contain asbestos, it is highly safe for the human body. Furthermore, the cement composition of the present invention is easy to manufacture and the product cost is low.

Claims (5)

[Claims] (1) Zinc oxide 35-60% by weight, rosin 20-40% by weight, diatomaceous earth 10-20% by weight, carboxyvinyl polymer and/or organic fatty acid 0.1-3.0% by weight
The composition consists of a generally powdered agent A and a generally liquid agent B, which are prepared by pulverizing and mixing 2 to 7% by weight of pulp fibers, and A cement composition characterized in that a kneaded mixture with the addition of is turned into cement. (2) The cement composition according to claim 1, wherein the carboxyvinyl polymer is a copolymer of acrylic acid and an allylated polyhydric alcohol. (3) The organic fat in agent A has the general formula C_nH_2_nCO
Organic saturated fatty acids corresponding to OH (however, n=10-22)
The cement composition according to claim 1. (4) The cement composition according to claim 3, wherein the organic fatty acid in agent A is a fatty acid that is solid at room temperature and is selected from the group consisting of lauric acid, myristic acid, palmitic acid, and stearic acid. (5) B agent is eugenol or clove oil; carbon number 10-2
Organic saturated fatty acid corresponding to the general formula C_nH_2_n_+_1COOH of 2; C_nH_2_n_-_1COOH
, C_nH_2_-_3COOHC_nH_2_n_-
_Organic unsaturated fatty acids corresponding to any of 5 COOH;
The cement composition according to claim 1, containing a component selected from the group consisting of propylene glycol, polyalkylene glycol, or a mixture of these glycol compounds; and olive oil.