JPS6266861A - Sterilizing reactor - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a sterilization reactor equipped with photosemiconductor fine particles having a photosterilizing effect immobilized on a base material and equipped as a filler.

Generally, various types of cells such as bacteria, microalgae, blood cells, animal and plant cells, etc., have been killed by using disinfectants or by applying heat.

However, in the case of foods, medicines, and various animals and plants, there are many cases in which both methods are inconvenient due to problems such as denaturation of materials and side effects. In particular, there is no effective method for sterilizing water such as drinking water and food, thinning algae membranes that inhibit the growth of agricultural products, and killing tumor cells.Therefore, there is an urgent need to develop a simple and effective sterilization device. It was wanted.

The present inventor previously proposed in Japanese Patent Application No. 59-196903 a method for killing various cells by utilizing the voltage generated in a non-conductor-supported optical semiconductor by light irradiation. This method does not use any disinfectants or heat, so it can kill cells without denaturing the material or causing side effects. Also, since it uses a non-conductor-supported optical semiconductor, there is no fear of elution of metal ions, and it is inexpensive. This enables reliable cell killing. However, at present, the particle size of the most active photosemiconductor particles is 0.
It is said that the diameter of microorganisms is less than 2 μm, and the diameter of microorganisms is generally several μm.
Considering that the separation of optical semiconductor particles and liquid to be treated can be easily achieved, it is an important practical technical problem to be solved when applying the invention of the prior application to foods, medicines, etc. It was proposed as.

In view of the above, the present inventors conducted extensive research and found that by fixing L-guiding particles to a base material, effective It was discovered that sterilization and mf separation can be achieved at the same time, and the present invention was achieved.

Hereinafter, the structure, action, effects, etc. of the present invention will be explained in more detail.

Sterilization (cell killing) targets almost all microscopic biological cells, including various microorganisms such as bacteria, actinobacteria, molds, microalgae, and yeast, as well as various animal and plant cells such as red blood cells, white blood cells, tumor cells, and cultured animal and plant cells. It can be.

All 10% conductor materials have the Denher effect, but the photovoltaic force is proportional to the logarithm of the electron-hole mobility ratio, and when this is 1, the photovoltaic force is zero. Therefore, in actual use, Ti0 has a -relatively large electron-hole mobility ratio.
=, RuO2, Cs:+Sb, I n A S, 1nS
Examples of suitable semiconductor materials include B, G, A, and the like.

a light-transmitting substance capable of holding a full amount of optical semiconductor fine particles on its surface;
For example, nitrocellulose, glass, polyvinyl chloride, plastic, nylon, methacrylic resin, polypropylene, etc. can all serve as this substrate. In particular, when a light-transmitting material is used as the base material, the expected utilization rate increases and becomes more preferable.

Further, the size and shape of the second base material (film-like, bead-like, board-like, fibrous-like 8) can be appropriately selected and used according to the end of the month of use of the JO & bacteria device.

Next, referring to the attached drawings, the structure of the sterilization reactor of the present invention can be explained as follows (1). In other words, FIG. 1 is a schematic cross-sectional view showing one example of the reactor of the present invention, and in the figure, a base material (2) carrying optical 'f-conductor fine particles is arranged in a plus tube (1). The same part is configured to be irradiated with light from the outside through a galley inlet tube (<1), and both ends of the glass tube (1) are connected to a liquid storage tank (3), forming a circulation system for the entire device. The water to be treated is circulated in the pipe by the Verista pump (4), and is sterilized by the L conductor fine particles as it passes through the base material (2).

The illustrated example uses a transparent glass material for the main part of the device, but it is also possible to use a light-impermeable material, such as plastic material, cement material, metal material, etc., for the same part, and install a light source inside the device. You may also do so. As a light source, a xenon lamp, a metal halide lamp, a fluorescent lamp, etc. can be suitably used, or a light source such as sunlight can be used! /8- This is the ability to introduce light into the device from a light source.

Hereinafter, the present invention will be explained in detail using experimental examples.

On the surface of a semi-dry film (14c+o') made by dissolving nitrocellulose 0,17 in acetone, 40 mg of Tie2 powder Aerongel Co., Ltd. ．． A fixed membrane was prepared. Dan.

The 9th day culture solution was mixed with αj concentration of 2.2×10 cells/
Microbial cell suspension 3. Insert this Ti0 = fixed film (21 mg77 cm') into 5+J, and turn on the Xe lamp (+
, 2X1f)'μE/m'5ec)
Ko. As a result, 50% in 60 minutes, 1()0% in X80 minutes
sterilization was observed. The experimental results are summarized in Figure 2. In the figure, the vertical axis is the number of [IhC) '11 bacteria, and the horizontal axis is the number 11 (l injection time).

Final experiment (+l-↑ Insert a spirally wound fixed membrane prepared in the same manner as in Experimental Example I into the tube 2), a glass tube (1), and a storage tube.
a, tank (3), peristaltic pump (Ato S, J-1
A sterilization reactor shown in FIG. 1 was constructed, consisting of 211) LA). Below is an example of an experiment using this device.

The culture solution of L',・qoli was cultured at a bacterial concentration of 1, fl
10 'cell Is/+111 bacterial cells (turbid liquid S
limp, T i (') 2 fixed membranes (T i
Sterilization was carried out using a one-piece sterilization reactor incorporating O = 160 + y). At this time, the flow rate is 300+nl'/
11, and the light source is a xenon lamp (light intensity 1.2X10
'μE#o''・5ee) was used.The result] :;
Sterilization of 10% at tJ minutes and 30% at 300 minutes was observed. The results are summarized in Figure 3, where the vertical axis is l+
The number of viable bacteria per J, the horizontal axis is the light irradiation time.

Next, 8 TiO fixed films (T 10232 U+n
5 k)n+('/l
+, and conducted an experiment with its (society). As a result, the killing rate was 70% in 60 minutes and 0 in 180 minutes (
)%. Furthermore, 12 Ti01 fixed films (Ti
e, when increasing the h to 480 mouths I9), tJ in 60 minutes,
l'l,%,3009tel 00%t)")j'ht
In either case, no decrease in the number of viable bacteria was observed in the control experiment in which the Ti2-immobilized membrane was not used.

In addition, it has been confirmed that the film on which the optical semiconductor particles are fixed can be reused, that is, it can withstand long-term use.

As detailed above, the present invention proposes an extremely useful sterilization reactor that does not require any disinfectant or heat, and by fixing optical semiconductor fine particles, the fine particles can be separated from food, water, and other objects to be treated. It can be said that this method has remarkable effects, such as the fact that the separation of the semiconductors can be achieved extremely easily, and since the optical semiconductor fixing film can be reused, the running cost of the device can be significantly reduced.

[Brief explanation of drawings]

attached! Figure S1 is a schematic sectional view showing an example of the sterilization reactor of the present invention, and Figures 275 to 4 are explanatory diagrams of experimental examples of the present invention. Also, in Figure 1, (1)......Glass tube, (2)
・・・・・・・・・・・・・・・'#:, Semiconductor semiconductor particle supporting permeable base material)・・・・・・・・・・・・Liquid storage tank and (4)・There is a peristaltic pump. Patent Applicant: Matsunaga Figure 2 Light eK Qiao 7 Chinki (h) Figure 3 Luminous emotion face P^ (1-t) Figure 4 Light, kiln counting time [MuJ

Claims (1)

[Claims] (1) A sterilization reactor characterized by having a photosterilizing filler formed by immobilizing optical semiconductor fine particles on the surface of a base material.