JPS62277168A - Temperature controller for centrifugal machine - Google Patents

Abstract

PURPOSE:To control the keeping temp. of a rotor with high precision and to carry out centrifugal separation with high accuracy by cutting off the power supply to a heater when the temp. of an evaporator on the outer periphery of the rotor of the centrifugal machine reaches a specified value against the set temp. of the rotor. CONSTITUTION:A temp. detector 13 is fixed to the evaporator 7 in the temp. controller of the centrifugal machine for separating and purifying a biological substance while keeping the substance at low temp. When the temp. of the temp. detector 13 reaches a set temp., a heater control signal is inputted, and the power supply to the heater is cut off. Consequently, the keeping temp. of the rotor 4 can be controlled with higher precision. As a result, centrifugal separation as well can be performed with high accuracy.

Description

Detailed Description of the Invention 3. Detailed Description of the Invention [Field of Industrial Application] The present invention relates to a temperature control device for a centrifuge, and more specifically, to a temperature control device for a centrifuge, and more specifically, to a device for controlling the temperature of a centrifuge, and more specifically, to a device for controlling the temperature of a centrifuge, and more particularly, to This invention relates to improvements in seed temperature control devices.

[Conventional technology]

A prior art related to temperature control in the case of separating and purifying biological substances by keeping them at low temperatures is disclosed in, for example, Japanese Patent Publication No. 58-904.

Conventionally, when controlling the temperature of a centrifuge rotor using the refrigerator number and heater on/off control, generally,
As shown in Figure 3, the heater or refrigerator is turned on and off depending on the set temperature of the temperature sensor (1) (the set temperature of the temperature sensor inside the double cylindrical adapter attached to the base located at the bottom of the rotor). The heater is turned off to control the temperature of the rotor, and the heater is turned on and off when the temperature of the temperature sensor (1) crosses the set temperature X, as shown by the dotted line in Figure 3. This is done using signals.

[Problem that the invention seeks to solve]

However, in the above-mentioned prior art 1, when trying to control the holding temperature of a centrifuge rotor with even higher precision, heating energy is adjusted to accommodate so-called environmental conditions such as the energy generated by the rotor and the rise in room temperature. It is regrettable that there is a lack of awareness regarding the addition of temperature control conditions.

The present invention has been made in consideration of the above points, and includes:
The purpose is to provide an improved temperature control device for a centrifuge that can control the holding temperature of the centrifuge rotor with even higher precision and, by extension, improve the precision of the centrifugal separation action itself. It is something.

That is, the present invention focuses on the fact that in order to control the holding temperature of a centrifuge rotor with high precision, it is sufficient to maintain the temperature around the rotor constant, and the present invention detects the surface temperature of the evaporator located around the rotor. Then, based on this detection signal,
It is designed to keep the temperature of the evaporator constant.

[Means for solving problems]

In order to achieve the above object, the present invention includes a temperature detection means for detecting the temperature of the rotor, an evaporator for cooling the rotor, a refrigerator for compressing and sending refrigerant to the evaporator, and a heater for heating the rotor. , a centrifuge having a controller that controls on/off a refrigerator and a heater so that the temperature of the rotor reaches a predetermined value in response to a temperature detection signal from the temperature detection means, wherein the evaporator is provided with a temperature sensor. However, the present invention is characterized in that it includes a system that cuts off power to the heater when the temperature of the evaporator reaches a certain value relative to the set temperature of the rotor based on a signal from the temperature sensor.

[Effect]

Therefore, by adopting the above configuration, the present invention provides the following features:
When the temperature of the evaporator located on the outer periphery of the centrifuge rotor reaches a certain value relative to the rotor's set temperature, the power to the heater is cut off. By adding heating energy corresponding to environmental conditions to the temperature control conditions, the rotor's holding temperature can be controlled with even higher precision.

〔Example〕

Hereinafter, the present invention will be explained based on an embodiment of the drawings. FIG. 1 is an explanatory diagram of the overall configuration of a centrifuge equipped with a temperature control device according to the present invention, and FIG. 2 is a temperature control circuit diagram of FIG. 1. , and FIG. 3 is a time chart showing the relationship between temperature-sensitive relay operating characteristics and temperature of the device of the present invention.

In Fig. 1, 1 is a steel ring constituting the rotor chamber 2, 3 is a door, 4 is a rotor, 5 is a motor that rotationally drives the rotor 4, and 6 is a through-air pump that makes the inside of the rotor chamber 2 transparent. ,
7 is an evaporator installed around the outer circumference of the rotor 4, 8 is a refrigerator that compresses and sends Freon to the evaporator 7, 9 is a heater, the sword is a power source for the heater, ■ is a temperature controller, and ν is installed at the bottom of the rotor 4. The temperature sensor (month, n is the temperature sensor (2) attached to the evaporator 7) in the double cylindrical adapter attached to the pace
), k is a temperature setting device, L5 is a hermetic seal, temperature controller] 1 is a temperature sensor (on the moon and temperature sensor (2
11: (This controls the on/off control of the heater 9 and the on/off control of the refrigerator 8. By the way, in the past, as mentioned above, the temperature indicated by No. 7) ν in FIG. Since the heater 9 and the refrigerator 8 were controlled on and off by the signal from the detector (1) only, the ON operation of the heater 9 shown in FIG. Accordingly, the temperature of the temperature sensor (1) 12 is A
There was a tendency to overshoot as shown by the dotted line between 4 and A5. This is because when the rotor 4 rotates at high speed, heat energy is provided by frictional heat with the surrounding air (the residual air of the ultrahigh-speed centrifuge, which rotates in a vacuum). Therefore, it is preferable to minimize the energy of the heater 9 in order to control the holding temperature of the rotor 4 with even higher precision. Therefore, in the present invention, as shown in FIG. As shown in FIG. 2, by adding the signal to the heater control signal, the on/off operation of the heater 9 shown in FIG. 3 can be controlled as H2 to H3 and H5 to H6. As a result, the temperature of the temperature sensor (1112) has a small overshoot as shown in FIG.

〔Effect of the invention〕

The present invention is as described above, and as is clear from the explanation of the illustrated embodiments, according to the present invention, the holding temperature of the centrifuge roller is controlled at a higher temperature, and the centrifugal separation itself is enhanced. Improved centrifuge temperature control can be obtained with increased precision.

[Brief explanation of drawings]

The drawings show one embodiment of the present invention, and FIG. 1 is an explanatory diagram of the overall configuration of a centrifuge equipped with a warm control device according to the present invention, FIG. 2 is a temperature control circuit diagram of FIG. 1, and FIG. is a time chart showing the relationship between temperature-sensitive relay operating characteristics and temperature of the device of the present invention. 40. rotor, 70. Evaporator, 89. Freezer, 90. Heater, X) is power supply for heater, ν9. Temperature detector (]),
131. Temperature detector (2). Name of patent applicant Hitachi Koki Co., Ltd. > Ward 1

Claims (1)

[Claims] 1. Temperature detection means for detecting the temperature of the rotor, an evaporator for cooling the rotor, a refrigerator for compressing and sending refrigerant to the evaporator, a heater for heating the rotor, and temperature detection from the temperature detection means. In a centrifugal machine having a controller that controls on/off a refrigerator and a heater so that the temperature of the rotor reaches a predetermined value according to a signal, the evaporator is equipped with a temperature sensor, and the temperature sensor A temperature control device for a centrifuge, comprising a system that cuts off power to the heater when the temperature of the evaporator reaches a certain value with respect to the set temperature of the rotor in response to the signal.