JPS62273065A - 液体中に懸濁した微細な固体粒物質を分別・分離するための装置 - Google Patents
液体中に懸濁した微細な固体粒物質を分別・分離するための装置Info
- Publication number
- JPS62273065A JPS62273065A JP62112666A JP11266687A JPS62273065A JP S62273065 A JPS62273065 A JP S62273065A JP 62112666 A JP62112666 A JP 62112666A JP 11266687 A JP11266687 A JP 11266687A JP S62273065 A JPS62273065 A JP S62273065A
- Authority
- JP
- Japan
- Prior art keywords
- centrifugal device
- inner cavity
- liquid
- capillary gap
- blood
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 title claims description 44
- 239000007787 solid Substances 0.000 title claims description 26
- 239000002245 particle Substances 0.000 title description 4
- 210000004369 blood Anatomy 0.000 claims description 48
- 239000008280 blood Substances 0.000 claims description 48
- 239000013618 particulate matter Substances 0.000 claims description 18
- 238000005194 fractionation Methods 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 16
- 230000004888 barrier function Effects 0.000 claims description 9
- 230000001154 acute effect Effects 0.000 claims description 5
- 239000011236 particulate material Substances 0.000 claims description 3
- 239000000523 sample Substances 0.000 description 16
- 238000000926 separation method Methods 0.000 description 16
- 239000000306 component Substances 0.000 description 14
- 239000000463 material Substances 0.000 description 12
- 230000001413 cellular effect Effects 0.000 description 9
- 239000012503 blood component Substances 0.000 description 8
- 210000003743 erythrocyte Anatomy 0.000 description 8
- 210000002966 serum Anatomy 0.000 description 7
- -1 polypropylene Polymers 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- 210000004027 cell Anatomy 0.000 description 5
- 210000001772 blood platelet Anatomy 0.000 description 4
- 238000005534 hematocrit Methods 0.000 description 4
- 230000000717 retained effect Effects 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 238000005119 centrifugation Methods 0.000 description 3
- 238000002405 diagnostic procedure Methods 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- 239000004698 Polyethylene Substances 0.000 description 2
- 239000004743 Polypropylene Substances 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920001155 polypropylene Polymers 0.000 description 2
- 230000009974 thixotropic effect Effects 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 229920002292 Nylon 6 Polymers 0.000 description 1
- 229920002302 Nylon 6,6 Polymers 0.000 description 1
- 102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
- 108700019535 Phosphoprotein Phosphatases Proteins 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 229940127219 anticoagulant drug Drugs 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 238000010261 blood fractionation Methods 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 210000003811 finger Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 210000005224 forefinger Anatomy 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000002489 hematologic effect Effects 0.000 description 1
- 229920001519 homopolymer Polymers 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002991 molded plastic Substances 0.000 description 1
- 210000001616 monocyte Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002689 polyvinyl acetate Polymers 0.000 description 1
- 239000011118 polyvinyl acetate Substances 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000005061 synthetic rubber Substances 0.000 description 1
- 210000003813 thumb Anatomy 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000003466 welding Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B7/00—Elements of centrifuges
- B04B7/08—Rotary bowls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
- B04B—CENTRIFUGES
- B04B5/00—Other centrifuges
- B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
- B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
Landscapes
- Centrifugal Separators (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US862301 | 1986-05-12 | ||
| US06/862,301 US4798577A (en) | 1986-05-12 | 1986-05-12 | Separator device and method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS62273065A true JPS62273065A (ja) | 1987-11-27 |
| JPH0217223B2 JPH0217223B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-04-19 |
Family
ID=25338167
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62112666A Granted JPS62273065A (ja) | 1986-05-12 | 1987-05-11 | 液体中に懸濁した微細な固体粒物質を分別・分離するための装置 |
Country Status (6)
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008540076A (ja) * | 2005-05-02 | 2008-11-20 | ヘングスト・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 遠心分離機用ロータ |
| US8323585B2 (en) | 2008-07-16 | 2012-12-04 | Ortho-Clinical Diagnostics, Inc. | Use of fluid aspiration/dispensing tip as a microcentrifuge tube |
| WO2014050605A1 (ja) * | 2012-09-28 | 2014-04-03 | 富士フイルム株式会社 | 遠心分離用容器 |
| WO2014157197A1 (ja) * | 2013-03-29 | 2014-10-02 | 富士フイルム株式会社 | 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法 |
| JP2014198281A (ja) * | 2013-03-29 | 2014-10-23 | 富士フイルム株式会社 | 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104522A (en) * | 1990-05-09 | 1992-04-14 | Wisconsin Alumni Research Foundation | Spray fractionation disks and method of using the same |
| JP3061414B2 (ja) * | 1990-06-04 | 2000-07-10 | アバクシス，インコーポレイテッド | 分析用回転装置および生物学的流体の分析方法 |
| US5906744A (en) * | 1997-04-30 | 1999-05-25 | Becton Dickinson And Company | Tube for preparing a plasma specimen for diagnostic assays and method of making thereof |
| US6524231B1 (en) * | 1999-09-03 | 2003-02-25 | Baxter International Inc. | Blood separation chamber with constricted interior channel and recessed passage |
| JP3619933B2 (ja) * | 2000-03-02 | 2005-02-16 | アークレイ株式会社 | 遠心分離用容器 |
| US7297272B2 (en) * | 2002-10-24 | 2007-11-20 | Fenwal, Inc. | Separation apparatus and method |
| US8685258B2 (en) * | 2008-02-27 | 2014-04-01 | Fenwal, Inc. | Systems and methods for conveying multiple blood components to a recipient |
| US8075468B2 (en) * | 2008-02-27 | 2011-12-13 | Fenwal, Inc. | Systems and methods for mid-processing calculation of blood composition |
| GB2477791B (en) * | 2010-02-15 | 2014-08-27 | Mann & Hummel Gmbh | Centrifugal separator with snap fit separation cone |
| GB201511039D0 (en) * | 2015-06-23 | 2015-08-05 | Karhiniemi Marko And Medigoo Oy And Karilahti Mika | In-vitro-analyser |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5168A (ja) * | 1974-06-19 | 1976-01-05 | Matsushita Electric Ind Co Ltd | Enshinbunryoki |
| JPS5229021A (en) * | 1975-08-29 | 1977-03-04 | Nissan Motor Co Ltd | Device for elevationally moving door glass for automobile |
| JPS5241508A (en) * | 1975-09-29 | 1977-03-31 | Fujitsu Ltd | Magnetic recording/reproding system |
| JPS534949A (en) * | 1976-07-02 | 1978-01-18 | Hitachi Ltd | Hydraulic circuit for winch |
| JPS5313254A (en) * | 1976-07-22 | 1978-02-06 | Fuji Electric Co Ltd | Blow-off air rectifying material using for open showcase and others |
| JPS542692A (en) * | 1977-06-08 | 1979-01-10 | Kinsekisha Lab Ltd | Support for piezooelectric vibrator and method of producing same |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US873593A (en) * | 1906-03-28 | 1907-12-10 | John W Phillips | Centrifugal separator. |
| GB499275A (en) * | 1937-06-15 | 1939-01-20 | Separator Ab | Improvements in and relating to the bowls of centrifugal separators |
| UST955355I4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1959-06-24 | 1900-01-01 | ||
| US3096283A (en) * | 1959-06-24 | 1963-07-02 | Becton Dickinson Co | Container for blood and machine for separating precipitates from liquid blood constituents |
| US3841838A (en) * | 1969-07-30 | 1974-10-15 | Rohe Scientific Corp | Centrifuge cups for automatic chemical analyzer |
| SU425665A1 (ru) * | 1972-04-04 | 1974-04-30 | Н. Е. Авдеев Воронежский технологический институт | Распределительная тарелка к центробежномусепаратору |
| US3813031A (en) * | 1972-08-02 | 1974-05-28 | Atomic Energy Commission | Rotor having sample holding means |
| US3847327A (en) * | 1973-06-04 | 1974-11-12 | Kobe Inc | Centrifugal separator |
| US3864089A (en) * | 1973-12-10 | 1975-02-04 | Atomic Energy Commission | Multiple-sample rotor assembly for blood fraction preparation |
| US3957653A (en) * | 1975-04-03 | 1976-05-18 | Becton, Dickinson And Company | Apparatus for collection, separation and isolation of blood |
| US4094461A (en) * | 1977-06-27 | 1978-06-13 | International Business Machines Corporation | Centrifuge collecting chamber |
| FR2400700A1 (fr) * | 1977-08-18 | 1979-03-16 | Guigan Jean | Dispositif de conditionnement d'un echantillon de liquide en vue de son analyse |
| FR2449467A1 (fr) * | 1979-02-23 | 1980-09-19 | Saget Pierre | Procede et appareil perfectionne le mettant en oeuvre pour la separation centrifuge d'au moins deux phases liquides d'un melange |
| DE2948177A1 (de) * | 1979-11-30 | 1981-06-04 | Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg, 6380 Bad Homburg | Separator fuer eine ultrazentrifuge |
| CA1152353A (en) * | 1980-05-05 | 1983-08-23 | Georges Revillet | Multicuvette rotor for analyser |
| NL8200725A (nl) * | 1982-02-23 | 1983-09-16 | Thomassen Holland Bv | Werkwijze en inrichting voor het afscheiden van deeltjes uit een gasstroom. |
| US4479789A (en) * | 1982-08-30 | 1984-10-30 | Richard Steimel | Bell-like centrifuge drum for continuously freeing metal turnings of oil |
| US4509941A (en) * | 1983-11-14 | 1985-04-09 | Miles Laboratories, Inc. | Fractionation device and method |
-
1986
- 1986-05-12 US US06/862,301 patent/US4798577A/en not_active Expired - Fee Related
-
1987
- 1987-04-29 DE DE8787106226T patent/DE3761353D1/de not_active Expired - Fee Related
- 1987-04-29 EP EP87106226A patent/EP0245703B1/en not_active Expired
- 1987-04-29 ES ES87106226T patent/ES2013268B3/es not_active Expired - Lifetime
- 1987-05-11 JP JP62112666A patent/JPS62273065A/ja active Granted
- 1987-05-11 AU AU72697/87A patent/AU577221B2/en not_active Ceased
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5168A (ja) * | 1974-06-19 | 1976-01-05 | Matsushita Electric Ind Co Ltd | Enshinbunryoki |
| JPS5229021A (en) * | 1975-08-29 | 1977-03-04 | Nissan Motor Co Ltd | Device for elevationally moving door glass for automobile |
| JPS5241508A (en) * | 1975-09-29 | 1977-03-31 | Fujitsu Ltd | Magnetic recording/reproding system |
| JPS534949A (en) * | 1976-07-02 | 1978-01-18 | Hitachi Ltd | Hydraulic circuit for winch |
| JPS5313254A (en) * | 1976-07-22 | 1978-02-06 | Fuji Electric Co Ltd | Blow-off air rectifying material using for open showcase and others |
| JPS542692A (en) * | 1977-06-08 | 1979-01-10 | Kinsekisha Lab Ltd | Support for piezooelectric vibrator and method of producing same |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008540076A (ja) * | 2005-05-02 | 2008-11-20 | ヘングスト・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 遠心分離機用ロータ |
| JP4753994B2 (ja) * | 2005-05-02 | 2011-08-24 | ヘングスト・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | 遠心分離機用ロータ |
| US8323585B2 (en) | 2008-07-16 | 2012-12-04 | Ortho-Clinical Diagnostics, Inc. | Use of fluid aspiration/dispensing tip as a microcentrifuge tube |
| WO2014050605A1 (ja) * | 2012-09-28 | 2014-04-03 | 富士フイルム株式会社 | 遠心分離用容器 |
| WO2014157197A1 (ja) * | 2013-03-29 | 2014-10-02 | 富士フイルム株式会社 | 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法 |
| JP2014198281A (ja) * | 2013-03-29 | 2014-10-23 | 富士フイルム株式会社 | 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法 |
| JP2014208330A (ja) * | 2013-03-29 | 2014-11-06 | 富士フイルム株式会社 | 遠心分離用容器および遠心分離装置並びにそれらを用いた遠心分離方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE3761353D1 (de) | 1990-02-15 |
| AU577221B2 (en) | 1988-09-15 |
| EP0245703B1 (en) | 1990-01-10 |
| EP0245703A3 (en) | 1988-07-13 |
| US4798577A (en) | 1989-01-17 |
| AU7269787A (en) | 1988-01-07 |
| JPH0217223B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1990-04-19 |
| ES2013268B3 (es) | 1990-05-01 |
| EP0245703A2 (en) | 1987-11-19 |
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