JPS62268570A - Electrode for iontophoresis - Google Patents
Electrode for iontophoresisInfo
- Publication number
- JPS62268570A JPS62268570A JP61112548A JP11254886A JPS62268570A JP S62268570 A JPS62268570 A JP S62268570A JP 61112548 A JP61112548 A JP 61112548A JP 11254886 A JP11254886 A JP 11254886A JP S62268570 A JPS62268570 A JP S62268570A
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- iontophoresis
- present
- adhesive
- view
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000853 adhesive Substances 0.000 claims description 5
- 230000001070 adhesive effect Effects 0.000 claims description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000011230 binding agent Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims 1
- 239000000126 substance Substances 0.000 description 3
- 239000002313 adhesive film Substances 0.000 description 2
- 239000012212 insulator Substances 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 229920002301 cellulose acetate Polymers 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000010220 ion permeability Effects 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
Landscapes
- Electrotherapy Devices (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】 本発明は、イオントフオレーゼ用電極に関する。[Detailed description of the invention] The present invention relates to an electrode for iontophoresis.
近時、心電図や脳波測定等の検知用途あるいは低周波治
療、イオントフオレーゼ（イオン浸透療法）等の刺激乃
至電流伝達用途等において、自己保形性、皮膚接着性並
びに導電性を併せ有する各種生体用電極が提案されてい
る。Recently, various living organisms that have self-shape retention, skin adhesion, and electrical conductivity have been used for detection applications such as electrocardiograms and electroencephalogram measurements, and for stimulation and current transmission applications such as low-frequency therapy and iontophoresis (iontophoresis). electrodes have been proposed.
しかし、これらの生体用電極は基材の保水性あるいは放
水性に劣り、イオントフオレーゼ、特にベプタイド等、
比較的分子量の大きな物質のイオントフオレーゼに関し
ては、十分にイオン透過性を発揮できないという欠、ヴ
を有していた。However, these biological electrodes have inferior water retention or water release properties of the base material, and are not suitable for iontophores, especially peptides, etc.
Iontophoresis, which is a substance with a relatively large molecular weight, has the drawback of not being able to exhibit sufficient ion permeability.
上記に鑑み本発明者らは鋭意研究の結果、分子量の大き
な物質は水溶液としてシャントイオントフオレーゼの形
で透過させるのが最も効率が良いこと、さらに、保水性
及び放水性に優れた支持体を電極に組み込（・ことによ
り上記繰作が容易に行なえることを知見し、本発明に至
ったものである。In view of the above, the present inventors have conducted extensive research and found that it is most efficient to transmit substances with large molecular weight in the form of shunt iontophoresis as an aqueous solution, and that a support with excellent water retention and water release properties is It was discovered that the above-mentioned operation can be easily performed by incorporating it into an electrode, leading to the present invention.
次に、本発明電極の構成等にっｂ詳細に説明する。Next, the structure of the electrode of the present invention will be explained in detail.
支持体
本発明剤を構成する支持体としては、保水性、放水性に
優れた材料が適当であり、紙、綿、ツール等Ｉ！＆維や
セルロースアセテート、ポリアクリルアミド等がより好
適に利用され得る。又、上記支持体の厚さは０．１〜２
ｍｍより好ましくは０．３−１ ｍｍとし、３０ ｃ
１０つ当り１００−２００ＡＩ４程度の薬液を保持でき
る様に調節する。Support Materials with excellent water retention and water release properties are suitable for the support constituting the agent of the present invention, such as paper, cotton, tools, etc. & fiber, cellulose acetate, polyacrylamide, etc. may be more preferably used. Further, the thickness of the support is 0.1 to 2
mm, preferably 0.3-1 mm, and 30 c
Adjust so that about 100-200 AI4 of chemical solution can be held per 10 bottles.
接着乃至結着剤
接着乃至結着剤は、本発明電極を皮膚へ確実に密着させ
るために使用するもので、ニトロセルロース系、ゴム系
、酢酸ビニルエマルノヨン系等が好適に利用され得る。Adhesive or binder The adhesive or binder is used to securely adhere the electrode of the present invention to the skin, and nitrocellulose-based, rubber-based, vinyl acetate emulsion-based, etc. can be suitably used.
形態としては、皮膚と保水支持体との接触を遮断しない
為に、多孔性のテープ状や網目状、基盤目状といった形
状とするのが好ましい。As for the shape, in order not to block contact between the skin and the water-retaining support, it is preferable to use a porous tape-like shape, a mesh-like shape, or a base mesh-like shape.
又、接着剤乃至結着剤のしめる面積は、電極総面積の２
０〜７０％程度、さらに、多孔性テープ使用時において
は、その微細孔の孔径は数μ〜数１００μより好ましく
は５μ〜５０μｍが適当である。Also, the area covered by the adhesive or binder is 2 of the total electrode area.
0 to 70%, and when a porous tape is used, the diameter of the micropores is preferably from several μm to several 100 μm, more preferably from 5 μm to 50 μm.
次に、本発明電極の全容を図面を参照しつつ説明する。Next, the entire structure of the electrode of the present invention will be explained with reference to the drawings.
第１図は、本発明の一実施例を下方から見た模式図であ
り、フィルム状絶縁体１上に伝導性部材２、さらに基盤
目上に接着剤３を上層し、その空間部に保水リザーバ４
を配置し、伝導性部材２をリード線に連結することによ
り、電極として機器本体と電気的に接続使用できる様に
したものである。又、第２図はその横断面図である。FIG. 1 is a schematic diagram of an embodiment of the present invention viewed from below, in which a conductive member 2 is layered on a film-like insulator 1, an adhesive 3 is further layered on a base layer, and water is retained in the space. Reservoir 4
By arranging the conductive member 2 and connecting the conductive member 2 to a lead wire, it can be electrically connected to the main body of the device as an electrode. Further, FIG. 2 is a cross-sectional view thereof.
さらに、もう一つ実施例を挙げる。第３図は横断面図で
あり、第４図は上方から見た模式図である。上から順に
フィルム状絶縁体１、伝導性部材２、保水リザーバ４、
粘着性フィルム５であり、粘着性フィルム５には一面に
微細孔をあけ、６はその微細孔を示す。又、図中７はパ
ワーサプライユニットであり、端子８．９により関連子
、不関導子１０．１１と電気的に接続されている。Furthermore, another example will be given. FIG. 3 is a cross-sectional view, and FIG. 4 is a schematic view seen from above. From top to bottom: film insulator 1, conductive member 2, water retention reservoir 4,
It is an adhesive film 5, and the adhesive film 5 has micropores formed on one side, and 6 indicates the micropores. Further, numeral 7 in the figure represents a power supply unit, which is electrically connected to related elements and unrelated conductors 10 and 11 through terminals 8 and 9.
第１図及び第３図は各々、本発明電極の一実施例の模式
横断面図である。
第２図は第１図に示した電極を下方から見たものであり
、第４図は第３図に示した電極を上方から見たものであ
る。
第１図
第２図
第３図
第４図FIG. 1 and FIG. 3 are each a schematic cross-sectional view of an embodiment of the electrode of the present invention. 2 is a view of the electrode shown in FIG. 1 from below, and FIG. 4 is a view of the electrode shown in FIG. 3 from above. Figure 1 Figure 2 Figure 3 Figure 4
Claims (1)
着剤を皮膚との接触面に均一に設けたことを特徴とする
イオントフォレーゼ用電極。(1) An electrode for iontophoresis, characterized in that a support with excellent water retention and water discharging properties and an adhesive or binder are uniformly provided on the surface in contact with the skin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61112548A JPS62268570A (en) | 1986-05-19 | 1986-05-19 | Electrode for iontophoresis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61112548A JPS62268570A (en) | 1986-05-19 | 1986-05-19 | Electrode for iontophoresis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS62268570A true JPS62268570A (en) | 1987-11-21 |
Family
ID=14589413
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61112548A Pending JPS62268570A (en) | 1986-05-19 | 1986-05-19 | Electrode for iontophoresis |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62268570A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03151982A (en) * | 1989-10-27 | 1991-06-28 | Korea Res Inst Of Chem Technol | Method and device for percutaneous administration of protain and peptide drug |
| JPH0880354A (en) * | 1994-09-14 | 1996-03-26 | Poritoronikusu:Kk | Percutaneous administration element |
| JP2018086071A (en) * | 2016-11-28 | 2018-06-07 | 株式会社リコー | Percutaneous absorption device and percutaneous absorption patch |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59118167A (en) * | 1982-12-24 | 1984-07-07 | 株式会社アドバンス | Conductor for iontophrese and plaster structure |
| JPS61149168A (en) * | 1984-10-29 | 1986-07-07 | メドトロニック・インコーポレーテッド | Ion introducing apparatus and method |
-
1986
- 1986-05-19 JP JP61112548A patent/JPS62268570A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59118167A (en) * | 1982-12-24 | 1984-07-07 | 株式会社アドバンス | Conductor for iontophrese and plaster structure |
| JPS61149168A (en) * | 1984-10-29 | 1986-07-07 | メドトロニック・インコーポレーテッド | Ion introducing apparatus and method |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03151982A (en) * | 1989-10-27 | 1991-06-28 | Korea Res Inst Of Chem Technol | Method and device for percutaneous administration of protain and peptide drug |
| JPH0614980B2 (en) * | 1989-10-27 | 1994-03-02 | コリア リサーチ インスティテュート オブ ケミカル テクノロジイ | Device for transdermal administration of protein and peptide drugs |
| JPH0880354A (en) * | 1994-09-14 | 1996-03-26 | Poritoronikusu:Kk | Percutaneous administration element |
| JP2018086071A (en) * | 2016-11-28 | 2018-06-07 | 株式会社リコー | Percutaneous absorption device and percutaneous absorption patch |
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