JPS62242671A - Remedy for cancer - Google Patents
Remedy for cancerInfo
- Publication number
- JPS62242671A JPS62242671A JP8435186A JP8435186A JPS62242671A JP S62242671 A JPS62242671 A JP S62242671A JP 8435186 A JP8435186 A JP 8435186A JP 8435186 A JP8435186 A JP 8435186A JP S62242671 A JPS62242671 A JP S62242671A
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- cell
- compound
- vitamin
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010028980 Neoplasm Diseases 0.000 title claims abstract description 13
- 201000011510 cancer Diseases 0.000 title claims abstract description 12
- 150000001875 compounds Chemical class 0.000 claims abstract description 8
- 239000000126 substance Substances 0.000 claims abstract description 3
- 239000003814 drug Substances 0.000 claims description 3
- 229940124597 therapeutic agent Drugs 0.000 claims description 3
- 150000003840 hydrochlorides Chemical class 0.000 claims 1
- 150000002823 nitrates Chemical class 0.000 claims 1
- 125000005360 alkyl sulfoxide group Chemical group 0.000 abstract description 5
- 230000000694 effects Effects 0.000 abstract description 5
- KYMBYSLLVAOCFI-UHFFFAOYSA-N thiamine Chemical compound CC1=C(CCO)SCN1CC1=CN=C(C)N=C1N KYMBYSLLVAOCFI-UHFFFAOYSA-N 0.000 abstract description 4
- 229960003495 thiamine Drugs 0.000 abstract description 4
- JZRWCGZRTZMZEH-UHFFFAOYSA-N Thiamine Natural products CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N JZRWCGZRTZMZEH-UHFFFAOYSA-N 0.000 abstract description 2
- 125000000217 alkyl group Chemical group 0.000 abstract description 2
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 2
- 230000002062 proliferating effect Effects 0.000 abstract description 2
- 230000035755 proliferation Effects 0.000 abstract description 2
- 235000019157 thiamine Nutrition 0.000 abstract description 2
- 239000011721 thiamine Substances 0.000 abstract description 2
- 229930003451 Vitamin B1 Natural products 0.000 abstract 2
- 239000011691 vitamin B1 Substances 0.000 abstract 2
- 235000010374 vitamin B1 Nutrition 0.000 abstract 2
- BWGNESOTFCXPMA-UHFFFAOYSA-N Dihydrogen disulfide Chemical compound SS BWGNESOTFCXPMA-UHFFFAOYSA-N 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 4
- 230000001590 oxidative effect Effects 0.000 description 2
- 150000003462 sulfoxides Chemical class 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 210000001266 CD8-positive T-lymphocyte Anatomy 0.000 description 1
- 208000000453 Skin Neoplasms Diseases 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 230000004099 anaerobic respiration Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 238000011257 definitive treatment Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000009169 immunotherapy Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 235000021179 potluck Nutrition 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
【発明の詳細な説明】
従来、癌の治療には、手術、放射線療法、化学療法、免
疫療法、などが、囃独、或いは併用で行なわれているが
、いずれも決定的な治療法とはいえない現状である。癌
治療の困難な原因の一つは圧縮能が正常ｔ８胞と分子レ
ベルに於ても差がないため正常ｍｎを損傷することなく
、圧縮能のみを死滅させることが困難な点にある。又、
座の末期において癌ＭＩＷｌの産出する壽素が患者を苦
しめ非惨な状態に陥れる為に、癌は恐ろしいとゆうこと
になる。本発明の目的は癌の有効な治ｇ薬を提倶するこ
とにある。本発明の治療薬は次の一般式で表される。[Detailed Description of the Invention] Conventionally, cancer treatment has been performed using surgery, radiotherapy, chemotherapy, immunotherapy, etc., either alone or in combination, but none of them are definitive treatments. The current situation is impossible. One of the reasons for the difficulty in cancer treatment is that there is no difference in compressive ability from normal T8 cells even at the molecular level, so it is difficult to kill only the compressive ability without damaging normal mn. or,
Cancer is said to be frightening because, in the final stage of the disease, the cancer produced by MIW1 torments the patient and puts them in a miserable state. An object of the present invention is to provide an effective therapeutic agent for cancer. The therapeutic agent of the present invention is represented by the following general formula.
こ１でＲは種々のアルキル基等を表すが、効果には殆ど
量系がない本化合物は一般名アルキルチアミンとよばれ
るビタミンＢＪＩであってそのｌ！ｌ！！害牲は充分に
証明されている。癌細胞と正常細胞は分子し〆ルで殆ど
差がないのであるが、正常細胞に比べて増殖が盛んなこ
とと、ｊ！１Ｍ素呼吸を行なう亭が持寄である。本発明
の化合物は、！ＩＩＩ？ｌ！内においてチアミン（ビタ
ミンＢ）とアルキルスルフォキサイドを生成することが
持寄であり、そのアルキルスルフォキサイドがその強力
な酸化作用と化学的活性によって抗菌力、抗癌力を発揮
するものである。即ち本化合物は盛んに増殖する癌細胞
により多くとりこまれ、そこでフルキルスルフォキサイ
ドが生成しその作用によってｉｍｐの増殖を坤え、つい
には消滅させるに至るのである。従って本化合物は大を
投与しても正常１８ｗｌ１に殆ど影響を与えることなく
治りすることができる。又癌ｔＩＡ胞の無酸素呼吸によ
って産出するｌ素をフルキルスルフォキサイドの持つ酸
化力かａｍ化することによって身体の抵抗力の低下を防
止し、治癒に役だつものである。癌は発生原因も部位も
禮々であるが、皮膚癌等は外用で、内臓その他は局所或
いは血管注射が有効である。In this 1, R represents various alkyl groups, etc., but this compound, which has almost no quantitative effect, is vitamin BJI, commonly known as alkylthiamine, and its l! l! ! The harm is well proven. Cancer cells and normal cells have almost no molecular differences, but they proliferate more actively than normal cells. The pavilion where 1M breathing is performed is a potluck. The compound of the present invention is! III? l! The secret is to produce thiamine (vitamin B) and alkyl sulfoxide within the body, and the alkyl sulfoxide exerts antibacterial and anticancer power through its strong oxidizing action and chemical activity. It is. That is, a large amount of this compound is taken up by actively proliferating cancer cells, where furkyl sulfoxide is produced, and its action suppresses the proliferation of imp, eventually leading to its extinction. Therefore, even if large doses of this compound are administered, normal 18wl1 can be cured without having almost any effect. In addition, the oxidizing power of furkyl sulfoxide converts the l element produced by anaerobic respiration of cancerous tIA vesicles into am, thereby preventing a decrease in the body's resistance and being useful for healing. Cancers have various causes and locations, but for skin cancers, etc., it is effective to use externally, and for internal organs, etc., local or vascular injections are effective.
特許出屓人 岩崎 孝男Patent author Takao Iwasaki
Claims (1)
化学式、表等があります▼ （塩酸塩、硝酸塩、等も含まれる。）[Claims] A therapeutic agent for cancer which is a compound represented by the following general formula ▲ Numerical formula,
There are chemical formulas, tables, etc.▼ (Includes hydrochlorides, nitrates, etc.)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8435186A JPS62242671A (en) | 1986-04-14 | 1986-04-14 | Remedy for cancer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8435186A JPS62242671A (en) | 1986-04-14 | 1986-04-14 | Remedy for cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS62242671A true JPS62242671A (en) | 1987-10-23 |
Family
ID=13828097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8435186A Pending JPS62242671A (en) | 1986-04-14 | 1986-04-14 | Remedy for cancer |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS62242671A (en) |
-
1986
- 1986-04-14 JP JP8435186A patent/JPS62242671A/en active Pending
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