JPS62222105A - Apparatus for analyzing activity of specimen such as animal - Google Patents

Abstract

PURPOSE:To make it possible to analyze the activity of a specimen without imparting stress to said specimen, by providing a Skinner box capable of permitting the activity of the specimen, a sensor, a device detecting the position of the specimen from the output of said sensor and a system for operationally processing the output from said device to record the same. CONSTITUTION:A Skinner box 21 having a size capable of permitting the action of a specimen 38 such as an animal is provided and a sensor 49 provided with a plurality of sets of light emitting elements L1-L6 and light receiving elements P1-P6 is provided in said box 21. The activity position of the specimen 28 in the box 21 is calculated in a range of setting positions O1-O9 from the elements L1-L6 and the elements P1-P6 by a position detecting circuit. The output of this circuit is operationally processed by a computer system to calculate the activity position, speed and activity direction of the specimen 28 to record the same. Environment such as light and darkness is freely set by an automatic environment setting apparatus and the supply of feed or water is performed by an accessory equipment apparatus. By this method, the activity of the specimen 28 in a normal state or at a specific abnormal time can be accurately analyzed without unprepared restriction due to various factors from the outside.

Description

DETAILED DESCRIPTION OF THE INVENTION "Field of Industrial Application" The present invention relates to an apparatus for analyzing the behavior of a specimen such as an animal under various conditions, including normal conditions as well as certain abnormal conditions.

"Prior Art" A conventional device of this type has a ball 1 as shown in FIG.
Rough within 1! - 12, etc., one end of the steel wire 13 is tied to the body of the rat 12, and the other end of the steel wire 13 is connected to the cam 1 via a ball bearing 14.
5 is connected, and the cam 15 is attached to a microswitch 17 on a frame 16. and,
When the specimen such as the rat 12 moves, the cam 15 rotates via the steel wire 13, and the microswitch 17 is accordingly turned on and off. This results in rat 12
The number of rotations and rotational speed of specimens such as rat 12 were measured, and from a physiological standpoint, the behavior that the specimens such as rat 12 might exhibit during normal times and certain abnormalities was measured and recorded. However, in the above method, since the specimen such as the rat 12 is tethered with the steel wire 13, the shackling of the specimen such as the rat 12 may have psychological effects on its behavior, causing stress or adding different behaviors. Or they may take completely different actions.
In addition, it is difficult to record for long periods of time, and from a physiological perspective, it becomes difficult to accurately measure and record behavior over long periods of time in a light and dark environment close to the specimen's natural environment. Ta.

"Problems to be Solved by the Invention" In view of the above circumstances, the present invention aims to solve the following problems:
Behavioral analysis of specimens such as animals that can accurately analyze the behavior of specimens in normal conditions or in certain abnormal situations without being subjected to stress such as careless restraint due to various external physical or psychological factors. The purpose is to provide equipment.

"Means to be Solved by the Invention" In order to achieve the above object, the present invention provides a Skinner box of a size that allows a specimen such as an animal to move, and a plurality of sets of light emitting elements and light receiving elements attached to the Skinner box. A sensor, a position detection device that determines the position of the specimen in the Skinner box from the output of the sensor, and arithmetic processing of the output of the position detection device to calculate and record the movement position, speed, and direction of movement of the specimen such as an animal. The present invention is characterized by an apparatus for analyzing the behavior of specimens such as animals, which comprises a computer system and an automatic environment setting device that can freely set environments such as brightness and darkness.

"Example" Below, an example of the behavior analysis apparatus for a specimen such as an animal according to the present invention will be described based on the drawings. In FIG. 1, 21 is
22 is a behavior monitoring device, 23 is an auxiliary equipment control device, 24 is an automatic light/dark environment setting device as the automatic environment setting device, 25 is an interface, and 26 is a microcomputer. And an interface 25, a microcomputer 26
, the printer constitutes a computer system including an action monitoring device 22 and an auxiliary equipment control device 23.

As shown in FIG. 2, the Skinner box 21 is formed into a box shape, and has a lid 27 that can be opened and closed to allow insertion of a specimen such as a rat 28, or can be detached and removed. An illumination lamp 29 is provided on the inner surface of the lid 27. The illumination lamp 29 is controlled by a computer system via an automatic brightness/dark environment setting device 1z4. A grid 30 is provided at the bottom of the skichy box 21, and the rat 2
The feces of the sample No. 8 is taken out and dropped onto a container 31. The take-out container 31 is the Skinner box 2
Of course, it is detachable from the beginning. A half mirror 32 is provided on at least one circumferential wall of the skinner box 21 so that the condition of a specimen such as a rat 28 can be visually observed, and the outside cannot be seen from the specimen. skichy box 21
There is a lever 33.3 inside that can be operated for specimens such as rats 28.
4, each lever 33, 34 actuating a respective microswitch 35, 36.

One of the microswitches 35 is the attached equipment control device 2.
3 to a feeder 37 for feeding food. When the feeder 37 operates, the tablet-shaped feed is fed into the tube 38.
The saw table 39 in the skichy box 21 is sent to the saw stand 39 via the skichy box 21. The other microswitch 36 is for applying electrical intracerebral stimulation to a specimen such as the rat 28 from a predetermined line of the beam bundle 40 via the accessory equipment control device 23 and the stimulation device described below. Other lines in the above-mentioned line bundle 40 are the cerebrum, cerebellum, and
is used to extract various information such as activity status from nerve cells such as the spinal cord. Historically, a nozzle 41 is attached to the skichy box 21, and a titration device 43 is connected to the nozzle 41 via a tube 42. The titration device 43 is a water tank 4
4, and each time water drips, the Yin and Yang electrodes 45.4 come in contact with the water and are electrically connected to each other.
6. Each Yin and Yang electrode 45°46 is a line 47.4
At 8, it is connected to the auxiliary equipment control device 23 mentioned above. Further, a sensor 49 is attached to the skinner box 21. The sensor 49 consists of a light-emitting element and a light-receiving element, which are used as a set, and as shown in FIG.
The light emitting elements L1 to L6 and the light receiving elements P1 to P6 are disposed at the lower part of the peripheral wall of the Skinner box 21, facing each other.

The light-emitting elements L1 to L6 and the light-receiving elements P, to P6 are arranged according to the size of the animal to be used as a specimen, and the distance between the light-emitting elements, the distance between the light-emitting elements, the distance between the light-emitting elements L6 to light-receiving elements P1 to P6, and the surrounding wall. The interval 'f4Dz is set, and the height H from the grid 30 is also set in the same way. On the other hand, the light emitting element Ll-L6
Even if the beam is blocked by the tail or snout of an animal such as a rat28, the diameter of the beam emitted from the specimen is determined only when the beam is blocked by a major part of the body such as the sinus. Set so that the subsequent device performs the processing operation.

Also, in the subsequent device, the processing operation is performed when the light reception value of the light receiving elements P, -P falls below a preset value, that is, when the amount of light shielding is higher than a certain value. Of course, the light emitted from the light emitting element L l""' L b is selected to have a wavelength that does not easily cause malfunction of the subsequent device due to other external light.

The behavior monitoring device 22 has a position detection circuit 51 connected to the light receiving elements P1 to P6 via an inverting amplifier 50, as shown in FIG. Of course, the inverting amplifier 50 always radiates a beam with a preset beam diameter toward the paired photodetectors P1 to P6.
The output signal is amplified, inverted, and sent to the position detection circuit 51. The position detection circuit 51 determines the action position of the subject such as the rat 28 in the squishy box 21 from the six sets of light emitting elements L1 to L6 and light receiving elements P1 to P6 at nine set positions 01 to 0. Figure 5 shows the type of information that can be determined within the range.

In other words, the position detection circuit 51 detects the light receiving elements P1 to P6.
The output lines p, +~Pb' of the inverting amplifier 50 corresponding to
In,output line,p,′,p,′,output line,P,
z'+4', output line P:l'+
P4', output line p,', p,', output line P2'+PS', output line Pff'+
S', output line p,', p6', output line p2
AND circuits 52a to 52i are connected to output lines Pff'+P6' and output lines Pff'+P6', respectively. Each A
NL) A monitoring light emitting diode 53a is connected to the output terminals of the circuits 52a to 52i via current adjustment resistors Ra-R1.
~ Connect 53i. Of course, the inverting amplifier 50 and the position detection circuit 51 may have various circuit configurations. The position detection circuit 51 includes a signal conversion circuit 54
It is connected to the above-mentioned interface 25 via. The signal conversion circuit 54 converts the output signal of the position detection circuit 51 corresponding to the time when the specimen such as the rat 28 is located at any of the nine set positions 01 to 09 into a one-shot pulse that is output only at the rising edge of the signal. It converts the signal into

The signal conversion circuit 54 includes an adder 5 as shown in FIG.
A counter 56 is also connected through 5. Then, the counter 56 indicates that the specimen such as the rat 28 is at the nine fixed positions 01 to 0. This is for monitoring purposes and counts each time it moves to either of the two locations.

The accessory equipment control device 23 is configured as shown in FIG. 6. First, the microswitch 35 is connected to a signal conversion circuit 57 that outputs a one-shot pulse every time it is turned on. The circuit 57 is connected to the microcomputer 26 via the interface 25 and also to the digital comparator 58. The digital comparator 58 is connected to the present circuit 59.
is connected, and the lever 3 is set by the preset device 59.
If the number of presses in step 3 is arbitrarily set, when the specimen such as the rat 28 presses the lever 33 by the set value, a signal is output to enable feeding, etc. each time the set value is reached.
It is connected to the microcomputer 26 via the interface 25, and the contact a of the selection switch SW1 is
Connect to the side.

The movable element C of the selection switch SWl is connected to the counter 60 and the open/close switch sw2. Connect to sw. The counter 60 is capable of counting and displaying and monitoring the number of times food is provided and the number of intra-behavioral stimuli given to a specimen such as a rat 28 which will be described later. One open/close switch SW2 is connected to the feeder 37 via a drive circuit 61. The other open/close switch SW is connected to the stimulation device 62. The stimulator 62 is
This is for applying electrical intracerebral stimulation to a subject such as the rat 28 from a predetermined line of the above-mentioned line bundle 40.

Furthermore, the above-mentioned unit 39 has a sensor 65 consisting of a light emitting element 63 and a light receiving element 64 that operate in response to the food of the specimen such as the rad 28, and the sensor 65 is equipped with a detection circuit 66.
A signal conversion circuit 67 that outputs a one-shot pulse every time a specimen such as the rat 28 eats is connected through the circuit. The signal conversion circuit 67 is connected to the contact of the selection switch S W + and is also connected to the microcomputer 26 via the interface 25. The circuit device that processes the outputs of the microswitch 35 and the sensor 65 is provided with two sets, that is, two channels, as shown in Part 6, and all of the two channels can be used only for the analysis of feeding behavior. Of course, one channel can be used for behavioral analysis of feeding, and the other channels can be used for behavioral analysis based on brain stimulation. In this case, the selection switch S
Of course, W1 and the open/close switches sw, , sw can be switched or opened/closed in accordance with the above behavior analysis.

Further, when performing behavioral analysis using brain stimulation, a microswitch 36 is used in place of the microswitch 35 in the circuit configuration shown in FIG. On the other hand, the titration device 4
Each of the three electrodes 45 , 46 is connected to a signal conversion circuit 69 via a detection circuit 68 .

The signal conversion circuit 69 outputs a one-shot pulse every time water is dropped in the titration device 43, and is connected to the interface 25, and also outputs a one-shot pulse each time water is dropped in the titration device 43. It is connected to a monitor counter 70 that counts and displays the number of times. In the interface 25, it is also possible to manually input the state of the activity of migrating cells of a sample such as the rat 28 from the line bundle 40 and process it in the microcombi 1-26, or it can be processed by another device. However, it is of course possible to record the information.

The automatic brightness/darkness environment setting device 24, as shown in FIG.
A power source is connected to the illumination lamp 29 through a relay 71, and a drive control circuit 72 such as a timer is connected to the relay 71. The skinner box 21 is provided with a sensor 73 that detects the amount of light from the illumination lamp 29.
A detection circuit 74 and an interface 2 are connected to the sensor 73.
A microcomputer 26 is connected via 5. The drive control circuit 72 can incorporate a program therein to control the lighting time of the lighting lamp 290, and can also be used to control the lighting time of the lighting lamp 29 by commands from the micro combinator 26. It is also possible to use a format that can be used.

Next, the operation of the arithmetic processing of the microcomputer 26 will be explained. First, a specimen such as rat 28 is moved into the horsetail box 21, and as shown in FIG. 8, measurement is started in step 1, and in step 2, the current month, day, and time are input using the keyboard. Then, in the microcomputer 26, various conditions, ie, initial values, such as setting the contents of the internal counter to zero, are set in step 3. Next, in step 4, a position signal is input from the light receiving element PI-PA, and in step 5, as time passes, there is a change in the movement of the specimen such as rat 28 at the set positions 1% 1101 to 09 of the nine points. In other words, it is determined whether or not the rat 28 specimen has moved. rough!・The 28th mag sample is at time T,
When changing from position N1 at time to position N2 at time T2,
Proceed to step 6, and if there is no change, proceed to step 13, which will be described later.

In step 6, the changed new position N2 is taken in, and in step 7, the time T at which the position changed to N2 is taken in.
Take in 2. Next, go to step 8, and this step 8
Then, 1 is added to the count corresponding to the position N2.

In other words, the microcomputer 26 sets the above nine points to the setting position 0. -O7 can be counted individually. Further, proceed to step 9. This step 9
Then, the change in position due to the movement of the rat 28 specimen N2-
The speed is calculated based on N, and the time T, -T, required for it. In the microcomputer 26, there are positions N,
The distance between and the position N2 is input in advance. In step 10, the moving speed of the specimen such as rat 28 calculated in step 9 is subjected to calculation processing to determine which rank among the four ranks it corresponds to. In step 11, the moving direction of the specimen such as the rat 28 is calculated as a vector from the position N1 before movement and the position N2 after movement. Furthermore, in step 12, the difference between the vector value indicating the movement direction of the rat 28 sample calculated in step 1-1 above and the hector value indicating the current movement direction is calculated, and from this the difference is calculated. Calculate the angle of movement, that is, the rotation angle. Next, the process proceeds to step 13, where it is determined whether the analysis experiment is finished. If not finished, step 4
Return to and repeat the above operation. When the process is completed, the process proceeds to any one of steps 14 to 19 and performs a processing operation.

In step 14, each data calculated in steps 6 to 12 is stored via the store data routine in step 20. Step 15 prints out the data generated in steps 6 to 12 via the output data routine of step 21. Step 16 transfers each data calculated in steps 6 to 12 to step 22.
Addition is performed in fixed time units such as 10 minute units through the at-data routine of . Step 17 is Step 6
The data calculated in steps 12 to 12 are output as a graph through the graphic display routine in step 23. In step 18, it is determined whether there is a re-instruction for movement analysis of the specimen such as rat 28 or not. If there is a command, the process returns to step 3, new initial values are set, and behavior analysis is performed. If there is no command, the process returns to step 14.

Step 19 determines whether the data processing has ended. Step 14 if data processing has not finished
If the process is completed, the process proceeds to step 24 and the processing operation is completed.

The processing operation by the computer 26 will be explained using a specific example. Figure 9 shows the output from step 14.20, which shows that within 1 minute from the start of the analysis experiment, the specimen 28 etc. was detected at O7 in the moving Narbosox 21.
The number of times it was located at the position was 6 times, and the number of times was 0. There were three times when the position was located at 0. The result is that the number of times the vehicle passed through the location is 4 times. Such processing is carried out in step 8 by adding one rat to each position O0 to O1.
6.22, the number of plates passed per minute was calculated. Also, in step 9, the moving speed of passing between each position 01 to 07 is calculated as 'Q', and in step 10, the first
Rank them as shown in Figure 0. In Figure 10, O~3
(cm/sec) Rank 1.3-5 (cm/sec) Rank 2.5-10 (cm/sec) Rank 3.10 ((To)
7 seconds) or more is classified into 4 levels with rank 4 being 4. As a result of the analysis experiment, data is obtained such that rank 1 occurs 20 times and rank 2 occurs 20 times within 5 minutes after the start of the experiment. In FIG. 10, based on the speed calculated in step 10, the number of times of each rank every 5 minutes is calculated in step 16.22, and this data is printed out as a graph in step 17.23. next,
The calculation of vector i will be explained. First, as shown in FIG. 11, the direction in which the specimen such as the rat 28 moves is set in advance at 8 points with the above 9 points set position Tt o + ~ 09 as the center.
The directions are determined and each direction is designated as O to 7 and inputted into the microcomputer 26. This direction O~7
is the vector i to be calculated in step 11. Therefore, the angle between each direction 0 to 7 is 45 degrees, with the clockwise angle being set as a negative value and the counterclockwise angle being set as a positive value. It is assumed that the specimen such as rat 28 in the skichy box 21 moves as shown by the arrow in movement diagram 2. In other words, the rat 28 sample is moved from the moving position O1 to 09,04.0
2, Os.

As is clear from FIG. 11, the vector values in this direction of movement are sequentially 2. l,? .

4.4.7. This is shown in FIG. 13, which is the vector value to be calculated in step 11. In step 12, subtraction processing is performed from the above vector value,
As shown in FIG. 13, -1 is calculated from the difference between vector values 1 and 2, vector difference 6 is calculated from vector values 1 and 7, and vector difference -3 is calculated from vector values 7 and 4. By the way, in the vector difference calculated in Fig. 13, -1
As shown in FIG. 11, indicates direction 7, that is, vector value 7, and vector difference -3 indicates direction 5, that is, vector value 5.

From this vector correction value, the rotation angle of movement as shown in FIG. 13 is calculated. For example, in FIG. 13, the vector correction value 7 is 145 degrees, as is clear from FIG.
Therefore, the rotation angle of the specimen such as rat 28 from the moving position O3 to 04 via O6 is 145 degrees. Thereafter, the rotation angle shown in FIG. 13 can be calculated for the angle vector correction value. If the rotation angle calculated in this way is processed in step 17.23 and printed out as a graph, as shown in Figure 14, the rotation angle of 180 degrees is 3
5 times, rotation angle of 135 degrees 42 times, etc. are obtained. It is also possible to print out each of the above data even during an experiment in which the behavior of a specimen such as rat 28 is analyzed.

Behavioral analysis of the rats and other specimens mentioned above not only outputs the time and number of times that the rat 28 specimens ate and received brain stimulation, but also the behavior before and after they ate and received brain stimulation as described above. It can be analyzed as follows.

The operation of the behavior monitoring device 22 when analyzing the behavior of a specimen such as the rat 28 as described above is such that signals from the light receiving elements PI to P6 of the sensor 49 are sent to the position detection circuit via the inverting amplifier 50 in accordance with the behavior of the specimen such as the rat 28. If 51 receives, the 5th
As shown in the figure, AND circuits 522 to 522 corresponding to the light receiving elements P I"' P q that emit the above-mentioned signals of the position detection circuit 51
52i operates to determine which of the preset positions O2 to 0° in the skichy box 21 the specimen such as the rat 28 passes through. The position signal of the specimen such as the rat 28 determined by the position detection circuit 51 is input to the signal conversion circuit 54, and the signal conversion circuit 54 outputs a one-shot pulse in response to the rising edge of the device signal constituted by the position detection circuit 51. The one-shot pulse output from the signal conversion circuit 54 is input to the microcomputer 26 via the interface 25, where it is subjected to arithmetic processing as described above, and is also sent to the adder 55.
The total number of passes through each of the nine set positions O9 to O9 is counted and displayed.

On the other hand, if the selection switch SWl shown in FIG. 6 is switched to the a side, the accessory equipment control device 23 can switch the signal conversion circuit 57 every time the specimen such as the rat 28 presses the lever 33 to feed. Outputs one-shot pulse. This one-shot pulse of the signal conversion circuit 57 is input to the microcomputer 26 via the interface 25,
The microcomputer 26 calculates and records the operating time of the lever 33, and the digital comparator 58
will also be provided. The digital comparator 58 compares the contents of the preset circuit 59, that is, the number of operations of the lever 33 for one feeding, and when the number of operations of the lever 33 matches the contents of the preset circuit 59, an output signal is sent to the selection switch. SWI, open/close switch SW2 and drive circuit 6
1 to drive the feeder 37 to supply food to the lotus stand 39, and the output signal is also input to the counter 60 via the selection switch SW to display the number of feedings. The data is sent to the microcomputer 26 via the microcomputer 25, which analyzes the time and frequency of feeding as well as the behavior before and after the feeding. At this time, open/close switch SW,
is separated. When the selection switch SW1 is switched to the b side, the sensor 65 detects each time a specimen such as a rat 28 eats the bait in the number of units 39, and the detection circuit 66 provides a detection signal to the signal conversion circuit 67. The signal conversion circuit 67 outputs a one-shot pulse every time it receives a detection signal,
This one-shot pulse is transmitted to the feeder 37 via the selection switch SW, the open/close switch SW2, and the drive circuit 61.
is driven to supply the next food to the lotus stand 39, and the one-shot pulse is also provided to the microcomputer 26 via the interface 25 to analyze the number of feedings and behavior before and after feeding. Moreover, the signal conversion circuit 6
The one-shot pulse No. 7 is also supplied to the counter 60 via the selection switch SW1 to count and display the number of feedings.

On the other hand, in other channels, the selection switch SW is opened and the open/close switch SW is closed, and the wire bundle 40 is connected to the intracranial nerve of the specimen such as the rat 28. Then, each time the specimen such as the rat 28 operates the lever 34, a one-shot pulse is output from the signal conversion circuit 57.
The one-shot pulse is inputted to the microcomputer 26 via the interface 25, whereby the number of operations of the lever 34, the operation time, etc. are calculated by the microcomputer 26 and recorded. Similarly to the above, the one-shot pulse of the signal conversion circuit 57 is compared in the digital comparator 58 with the contents of the preset circuit 59 in which the number of operations of the lever 34 is set, and only when the one-shot pulse matches the contents, the one-shot pulse is output from the digital comparator 58. The signal is output and simultaneously fed to the stimulation device 62 via the selection switch SWl and the open/close switch SW:l, and the stimulation device 62 applies brain stimulation to the specimen such as the rat 28, and the output signal of the digital comparator 58 is selected. switch SW
1, the number of times the brain stimulation is given is counted and displayed by a counter 6G.

Furthermore, the output signal of the digital comparator 58 is also provided to the microcomputer 26 via the interface to analyze the time and number of times that intracerebral stimulation was applied to the specimen such as the rat 28, and the movements before and after the intracerebral stimulation was applied. It goes without saying that the microcomputer 26 is capable of analyzing the state of the brain nerves of a specimen such as the rat 28 during various behaviors by taking the information from the radiation bundle 40.

Next, when the rat 28 sample drinks water from the nozzle 41,
The dirt is detected by each electrode 45, 46 and the detection circuit 68, and the signal conversion circuit 69 receives the detection signal from the detection circuit 68 and outputs a one-shot pulse. The one-shot pulse is sent to the microcomputer 26 via the interface 25.
The microcomputer 26 analyzes the time and number of times the sample, such as the rat 28, drinks water, as well as the behavior before and after drinking water. The one-shot pulse outputted from the signal conversion circuit 68 is also supplied to a counter 70, which counts and displays the number of times the specimen, such as the rat 28, drinks water.

The automatic bright/dark environment setting device 24 has a drive control circuit 72 controlling the lighting time and amount of illumination of the illumination lamp 29 via the relay 71 to artificially create day and night for the specimen such as the rat 28. input the control state of the illumination lamp 29 from the sensor 73 to the microcomputer 26 via the detection circuit 74 and the interface 25;
The microcomputer 26 analyzes the behavior of the specimen such as the rat 28 at this time as described above. The above lighting lamp 29
In addition, a heater or a cooler may be attached to the skinner box 21, and the heater or cooler may be controlled by the automatic environment setting device in exactly the same manner as the automatic brightness/darkness environment setting device 24.

“Effects of the Invention” As described above, the movement solution for animal specimens, etc. according to the present invention If W
``According to It, a specimen such as a rat is not subject to careless constraints from various external physical or psychological factors, and the behavior of the specimen under normal conditions or certain abnormalities can be accurately determined. It is very convenient because it can be analyzed in detail.

[Brief explanation of drawings]

Fig. 1 is a configuration diagram showing an embodiment of the behavioral analysis device for animal specimens according to the present invention, Fig. 2 is a sectional view showing the structure of the Skinner box, and Fig. 3 is the setting of nine points in the Skinner box. An explanatory diagram showing the position, Fig. 4 is a block diagram of the behavior monitoring device, Fig. 5 is a circuit diagram of the position detection circuit, Fig. 6 is a block diagram of the attached equipment control device, and Fig. 7 is a block diagram of the automatic brightness/dark environment setting device. Block diagram, Figure 8 is a flowchart showing the processing operation of the microcomputer, Figure 9 is a diagram showing the state in which a specimen such as a rat passes through the 9 set positions in the Skinner box, and Figure 10 is the 9 points in the Skinner box. Diagram 11 showing an example of the speed at which a specimen such as a rat passes within the set position of the point.
The figure shows the direction in which the specimen such as a rat moves in the Skinner box, the designation number # of Peltle, Figure 12 is a diagram showing an example of the behavior of the specimen such as a rat, and Figure 13 shows the direction in which the specimen such as a rat in Figure 12 moves. Figure 14 shows an example of the behavior of a specimen such as a rat expressed in terms of the number of rotation angles; Figure 15 is an explanation of a conventional behavior analysis device for specimens such as animals. It is a diagram. 21...Skinner box 22...Behavior monitoring device 23...Attached equipment control device 24...Automatic brightness/dark environment setting device 25...Interface 26...Microcomputer Patent applicant Narishige Scientific Instruments Co., Ltd. Laboratory D2
DIDI D2 Figure 5 ζ1 Figure 9 Figure 10 Figure 11 Figure 12

Claims (1)

[Claims] A Skinner box large enough for animals and other specimens to move,
A sensor including a plurality of sets of light-emitting elements and light-receiving elements attached to the Skinner box, a position detection device that determines the position of the specimen in the Skinner box from the output of the sensor, and a calculation processing of the output of the position detection device to detect the animal. An apparatus for analyzing the behavior of specimens such as animals, which comprises a computer system that calculates and records the movement position, speed, and direction of movement of specimens, and an automatic environment setting device that can freely set environments such as brightness and darkness.