JPS6214780B2 - - Google Patents
Info
- Publication number
- JPS6214780B2 JPS6214780B2 JP55006662A JP666280A JPS6214780B2 JP S6214780 B2 JPS6214780 B2 JP S6214780B2 JP 55006662 A JP55006662 A JP 55006662A JP 666280 A JP666280 A JP 666280A JP S6214780 B2 JPS6214780 B2 JP S6214780B2
- Authority
- JP
- Japan
- Prior art keywords
- electrode
- enzyme
- working electrode
- reaction tank
- simultaneous measurement
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000005259 measurement Methods 0.000 claims description 25
- 238000006243 chemical reaction Methods 0.000 claims description 19
- 102000004190 Enzymes Human genes 0.000 claims description 18
- 108090000790 Enzymes Proteins 0.000 claims description 18
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 16
- 108010093096 Immobilized Enzymes Proteins 0.000 claims description 8
- 239000012085 test solution Substances 0.000 claims description 6
- 238000006911 enzymatic reaction Methods 0.000 claims description 3
- 239000007788 liquid Substances 0.000 description 12
- 238000012360 testing method Methods 0.000 description 11
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 5
- 239000001301 oxygen Substances 0.000 description 5
- 229910052760 oxygen Inorganic materials 0.000 description 5
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 5
- 239000013060 biological fluid Substances 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 4
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 4
- 108090000854 Oxidoreductases Proteins 0.000 description 3
- 102000004316 Oxidoreductases Human genes 0.000 description 3
- 235000012000 cholesterol Nutrition 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 3
- 102000057621 Glycerol kinases Human genes 0.000 description 2
- 101710163410 Probable glycerol kinase Proteins 0.000 description 2
- LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 description 2
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 2
- 239000004809 Teflon Substances 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 2
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 150000001840 cholesterol esters Chemical class 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- 229940109239 creatinine Drugs 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000007772 electrode material Substances 0.000 description 2
- 238000000855 fermentation Methods 0.000 description 2
- 230000004151 fermentation Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 108010090622 glycerol oxidase Proteins 0.000 description 2
- 108010054790 glycerol-3-phosphate oxidase Proteins 0.000 description 2
- 239000012212 insulator Substances 0.000 description 2
- 235000014655 lactic acid Nutrition 0.000 description 2
- 239000004310 lactic acid Substances 0.000 description 2
- 229940067631 phospholipid Drugs 0.000 description 2
- 150000003904 phospholipids Chemical class 0.000 description 2
- 229910052709 silver Inorganic materials 0.000 description 2
- 239000004332 silver Substances 0.000 description 2
- 229940116269 uric acid Drugs 0.000 description 2
- 210000002700 urine Anatomy 0.000 description 2
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108010089254 Cholesterol oxidase Proteins 0.000 description 1
- 108010000659 Choline oxidase Proteins 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 108010077078 Creatinase Proteins 0.000 description 1
- 108010066906 Creatininase Proteins 0.000 description 1
- 108010022355 Fibroins Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 108010073450 Lactate 2-monooxygenase Proteins 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 108010013563 Lipoprotein Lipase Proteins 0.000 description 1
- 102100022119 Lipoprotein lipase Human genes 0.000 description 1
- 102000011420 Phospholipase D Human genes 0.000 description 1
- 108090000553 Phospholipase D Proteins 0.000 description 1
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 1
- 108010042687 Pyruvate Oxidase Proteins 0.000 description 1
- 108010060059 Sarcosine Oxidase Proteins 0.000 description 1
- 102000008118 Sarcosine oxidase Human genes 0.000 description 1
- 102000000019 Sterol Esterase Human genes 0.000 description 1
- 108010055297 Sterol Esterase Proteins 0.000 description 1
- 102000014384 Type C Phospholipases Human genes 0.000 description 1
- 108010079194 Type C Phospholipases Proteins 0.000 description 1
- 108010092464 Urate Oxidase Proteins 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000002952 polymeric resin Substances 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229940076788 pyruvate Drugs 0.000 description 1
- 229940107700 pyruvic acid Drugs 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229910052703 rhodium Inorganic materials 0.000 description 1
- 239000010948 rhodium Substances 0.000 description 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- -1 serum and plasma Substances 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP666280A JPS56103364A (en) | 1980-01-22 | 1980-01-22 | Simultaneous measuring apparatus for multi-items |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP666280A JPS56103364A (en) | 1980-01-22 | 1980-01-22 | Simultaneous measuring apparatus for multi-items |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56103364A JPS56103364A (en) | 1981-08-18 |
| JPS6214780B2 true JPS6214780B2 (OSRAM) | 1987-04-03 |
Family
ID=11644585
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP666280A Granted JPS56103364A (en) | 1980-01-22 | 1980-01-22 | Simultaneous measuring apparatus for multi-items |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56103364A (OSRAM) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5968663A (ja) * | 1982-10-14 | 1984-04-18 | Fuji Electric Corp Res & Dev Ltd | 発酵もろみ中の糖およびアルコ−ルの定量法 |
| KR101097238B1 (ko) | 2009-10-06 | 2011-12-21 | 주식회사 케이씨텍 | 혈당 측정 패치 및 이를 이용한 혈당 측정 장치 |
-
1980
- 1980-01-22 JP JP666280A patent/JPS56103364A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56103364A (en) | 1981-08-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4935105A (en) | Methods of operating enzyme electrode sensors | |
| RU2292841C2 (ru) | Способ определения адекватности объема пробы в устройствах биодатчиков | |
| EP0406304B1 (en) | Method and apparatus for amperometric diagnostic analysis | |
| TWI453401B (zh) | 使用時間解析電流測定法之用於分析物濃度測定的系統及方法（一） | |
| JP4573400B2 (ja) | 電気化学的測定のタイミングを開始するための試料の検出 | |
| CN101896619B (zh) | 速读门控电流分析法 | |
| US7338802B2 (en) | Method of performing calibration and quality control of a sensor and apparatus for performing the method | |
| US5108564A (en) | Method and apparatus for amperometric diagnostic analysis | |
| EP0537761A2 (en) | A biosensor and a method for measuring a concentration of a substrate in a sample | |
| JP2000507457A (ja) | 酵素センサ | |
| WO1995022051A1 (en) | Diagnostic flow cell device | |
| JPWO2008044530A1 (ja) | 多項目成分分析センサおよび多項目成分の測定方法 | |
| KR20100005209A (ko) | 비선형 샘플 응답을 이용한 분석물 측정을 위한 시스템 및 방법 | |
| Pundir et al. | Construction of an amperometric triglyceride biosensor using PVA membrane bound enzymes | |
| KR20130092571A (ko) | 대조 용액에 대한 글루코스 결과의 온도 보정의 정확도 개선을 위한 시스템 및 방법 | |
| Pemberton et al. | An assay for the enzyme N-acetyl-β-D-glucosaminidase (NAGase) based on electrochemical detection using screen-printed carbon electrodes (SPCEs) | |
| Mascini et al. | Determination of free and total cholesterol in human bile samples using an enzyme electrode | |
| Campanella et al. | Enzyme sensor for the determination of choline-containing phospholipids in some biological fluids | |
| JP3487410B2 (ja) | バイオセンサ | |
| JPS6214780B2 (OSRAM) | ||
| GB2063479A (en) | Apparatus for Continuous Determination of a Plurality of Solution Components | |
| US5741709A (en) | Multiple injection analysis | |
| KR101490186B1 (ko) | 전도성 고분자 전극을 이용한 전기화학적 콜레스테롤 센서 및 그 제조방법 | |
| Satoh | [18] Biomedical applications of the enzyme thermistor in lipid determinations | |
| JP2543057B2 (ja) | バイオセンサの製造方法およびバイオセンサ用電極板の製造方法 |