JPS62106341A - Distributive injection apparatus - Google Patents

Abstract

PURPOSE:To attain the simplification of a mechanism and the miniaturization of the titled apparatus, by providing a distributive injection chip push-out member sliding along the outside of the body and a distributive chip detaching member to work in conjunction with a plunger driving mechanism. CONSTITUTION:A distributive injection chip push-out member 11 sliding along the outside of a body part 3 and a distributive injection chip detaching member 12 to work in conjunction with a plunger driving mechanism are provided. A feed mechanism 9 is driven to position a new distributive injection chip 1 under a frictional engaging part 2 and an up-and-down driving mechanism 7 is driven to fall the frictional engaging part 2 to engage the distributive injection chip 1 with the frictional engaging part 2. The plunger driving mechanism is driven to raise a plunger 5 to suck a sample and the plunger 5 is subsequently fallen to emit the sample. Thereafter, the plunger driving mechanism is driven to move the distributive injection chip push-out member 11 downwardly to push the distributive injection chip detaching member 12 to detach the distributive injection chip 1. By this mechanism, the simplification of the mechanism and the miniaturization of the apparatus are attained.

Description

DETAILED DESCRIPTION OF THE INVENTION Field of Application of the Invention The present invention relates to a dispensing device that transfers liquid samples between a plurality of containers, and in particular a dispensing tip that is disposable to prevent cross contamination between samples. The present invention relates to a dispensing device suitable for automatically exchanging.

[Background of the invention]

Conventional equipment that handles disposable dispensing tips includes:
Two drive mechanisms were provided separately: a plunger drive mechanism used to suck and discharge the sample, and a solenoid drive detachment plate for removing the dispensing tip (Japanese Patent Laid-Open No. 1986-59
-147268). This makes the mechanism complicated and also causes the device to become larger.

[Purpose of the invention]

An object of the present invention is to provide a dispensing device that can simplify the mechanism for handling disposable dispensing tips and downsize the device.

[Summary of the invention]

The present invention provides a dispensing tip extrusion mechanism that works in conjunction with a plunger drive mechanism, and allows the dispensing tip to be removed by moving the dispensing tip extrusion mechanism downward.

[Embodiments of the invention]

An embodiment of the present invention will be described below with reference to FIG. The dispensing device includes a friction engagement part 2 for attaching and detaching a dispensing tip 1. A body part 3 located above the frictional engagement part 2, an atmosphere communication hole 4 passing through the frictional engagement part 2 and the body part 3, a plunger 5 that moves up and down within the atmosphere communication hole 4, a stepping motor 6a, a coupling 6b, a ball screw. 6c, plunger holding member 6d
, a plunger drive mechanism 6. consisting of a plunger vertical moving part 6e, and a bearing member 6f. motor 7a, vertical moving section 7b,
A northward drive mechanism 79 is made of a bearing member 7c and moves the part from the N friction engagement part 2 to the plunger drive mechanism 6 up and down.
A transport mechanism 9 that transports the dispensing tip 1 and the container 8 (moves in a direction perpendicular to the plane of the paper).

Plunger drive mechanism 6. , h, and a controller 10 that controls the operation of the lower drive mechanism 7 and the transport mechanism 9. In this embodiment, a dispensing tip push-out member 11 and a dispensing tip removing member 12 that slide on the outside of the body portion 3 in conjunction with the plunger drive mechanism 6 are provided. This dispensing tip removal member 12 is effective as a stopper for tip positioning when the dispensing tip 1 is inserted. Next, a plan view PL diagram of this embodiment is shown in FIG. The transport mechanism 9 in this embodiment includes a transport platform 9a on which the dispensing tip 1 and the container 8 are mounted.
, a transport mechanism 9b (for example, a linear stepping motor) that drives the transport table. Note that a disposal hole 13 for discarding the dispensing tip 1 is provided below the friction engagement part 2, and the dispensing tip 1 can be discarded when the conveyance table 9a passes through the discarding hole 13. do. In addition, there is also a mechanism for supplying the dispensing tip 1 and container 8 to the transport table 9a, but it is not shown here.

The operation of this embodiment consists of the following steps.

1) The transport mechanism drives 9 to position a new dispensing tip below the frictional engagement part 2.

2) Drive the vertical pressure a mechanism 7 to lower the frictional engagement part 2 and fit the dispensing tip into the frictional engagement part 2. At this time, since the dispensing tip removal member 12 serves as a stopper, the fitting position of the dispensing tip 1 can be determined with high precision.

3) Drive the vertical drive mechanism 7 to raise the dispensing tip fitted into the friction engagement part 2.

4) Position the container containing the sample to be inhaled below the frictional engagement part 2.

5) Lower the dispensing tip fitted into the friction engagement part 2 and dip it into the sample liquid to be aspirated.

6) Plunger drive Ft! 6 and plunger 5
inhale the sample.

7) Raise the dispensing tip that has inhaled the sample.

8) Position the container into which the inhaled sample is transferred below the dispensing tip.

9) Lower the dispensing tip that has aspirated the sample.

10) Plunger drive 4. ! ! Drive W E3 to lower the plunger and discharge the sample.

11) Raise the dispensing tip.

12) Move the transport table 9a and place the dispensing tip disposal hole 13 below the dispensing tip 1. Let it come out.

13) Drive the plunger drive mechanism 6 to move the dispensing tip push-out member 11 downward, push the dispensing tip removing member 12, and remove the dispensing tip 1. Then return to step 1).

In the above embodiment, the dispensing tip 1 was removed via the dispensing tip removal member 12, but if the positioning accuracy of inserting the dispensing tip is not particularly required, another method is shown in Fig. 3. As shown, it is also conceivable to directly remove the dispensing tip 1 with the dispensing tip extrusion member 11 through the through hole 14.

〔Effect of the invention〕

As described above, according to the present invention, since the mechanism for driving the plunger and the mechanism for removing the dispensing tip can be used in common, it is possible to simplify the mechanism and downsize the device.

[Brief explanation of drawings]

FIG. 1 is a structural diagram of a dispensing device according to an embodiment of the present invention, FIG. 2 is a schematic plan view of this embodiment, and FIG. 3 is a partial diagram of another embodiment. 1... Dispensing tip, 2... Frictional engagement part, 6...
Plunger drive mechanism, 8... Container, 1... Dispensing tip pushing member, 12... Dispensing tip removing member.

Claims (1)

[Claims] 1. A frictional engagement part for attaching and detaching a dispensing tip, a body part located above the frictional engagement part, an atmospheric communication hole penetrating the frictional engagement part and the body part, and a plunger that moves within the atmospheric communication hole. , a plunger drive mechanism that moves the plunger, a drive mechanism that changes the vertical relative position of the frictional engagement part and the container, a container transport mechanism, and a controller that controls the operations of all of the above drive mechanisms. A dispensing tip extrusion mechanism interlocked with the plunger drive mechanism is provided, and the dispensing tip is removed by moving the dispensing tip extrusion mechanism downward. Dispensing device.