JPS6197227A - Pasty remedy for athlete's foot - Google Patents

Abstract

PURPOSE:To provide the titled remedy for athlete's foot composed mainly of extracted liquid of hibiscus. CONSTITUTION:Extracted liquid of the root of hibiscus is deodorized with activated charcoal and mixed with salicyclic acid, glycerol and lactic acid to obtain a pasty composition, which is used as the base. A fatty acid, an aliphatic higher alcohol and glycerol are mixed and dissolved in the base under heating, and the resultant solution is mixed with an aqueous solution of potassium carbonate to obtain aliphatic potassium carbonate salt. 1pt. of the aliphatic potassium carbonate salt is mixed with 2pts. of the base. The obtained mixture is kneaded with 7-10% bentonite, then with 5-10% lanolin to obtain the objective pasty remedy for athlete's foot. Salicylic acid acts as a disinfectant, lactic acid mitigates the stimulation of the salicylic acid, lanolin protects the surface of the diseased skin, and bentonite reduces the viscosity and mitigates the irritant action of each component to the skin.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a paste-like athlete's foot medicine containing an extract of Aspergillus orientalis as a main ingredient.

Huangshu Aoi (hereinafter referred to as "Tororo Aoi") is a perennial plant, and the extract (mucilage) obtained from its roots is called Neri and is used for making washi paper, and is also used as a medicine. It is well known that if the roots of A. japonica are damaged when digging them up or washing them with water to remove mud, the roots themselves and the extract itself will rot very quickly. It is a plant root that must be handled with care as it emits a foul odor, and both the root and its extract lack shelf life.

Another characteristic of the extract is that the rate of viscosity reduction is extremely rapid, and for this reason, there is a strong need for the development of a method for preserving A. japonica root and its extract, and a method for preventing viscosity reduction.

As a result of many years of research, the applicant has succeeded in providing a method for preventing putrefaction of the root of A. japonica and its extract, and a hair conditioner, liniment, and other medicinal ointments using the extract as the main raw material. The present invention is one of these.

The present invention aims to provide a paste-like athlete's foot medicine that uses the extract of A. japonica as an active ingredient.

The present invention will be explained in detail below.

Tororo mallow is an annual plant whose root extract is extremely viscous and is used as neri when making washi paper.
It is also known that if the roots are damaged, they tend to rot, and if the extract is not used promptly, they tend to rot, and the activated carbon, which is the lifeblood of the root, deteriorates very quickly. Therefore, when digging up the thorn mallow from the soil, be careful not to damage the roots, and do not wash it (with the soil still adhering to the roots). In a 7% solution,
Soak and store in a cool, dark place.

■ Immerse in a 3% to 5% salt solution and store in a cool, dark place 〇 ■ Immediately wash the roots of A. japonica with water, immerse in shochu at 35 degrees to the extent that the A. japonica roots do not come into contact with air, and store in a cool, dark place.

Now, to give an example of a method for extracting ingredients from preserved A. japonica using the method described above, the preserved A. japonica root is washed thoroughly with water as soon as possible (
Wash away soaking liquid and anti-soil deposits.

) Sprinkle activated carbon in an amount of 10% of this A. roro mallow device, leave it in the device for 1 to 2 days, then add the same amount of water as the troro mallow roots, leave it for another 1 to 2 days, and then wash with water. The activated carbon is removed, and the roots of A. japonica are crushed, and the roots are immersed in the same amount of shochu or 25-30% alcohol as in the . This extract has a fairly high viscosity.

Note that room temperature water extraction may be performed using the same amount of water as the crushed plate.

The number of days to soak in shochu or alcohol (extraction days) is
When the season is from spring to summer, it is about 1 to 2 days, and from autumn to winter, it is about 5 to 7 days.

In such cases, a colorless and transparent component is extracted from the root of the molasses in a soaking tank.

Although this extract has a high viscosity, under normal conditions it is easily putrefied due to the growth of spoilage bacteria, and the viscosity decreases significantly over time.

Here are some examples of how to prevent spoilage and viscosity reduction of the A. japonica extract extracted using this method: ■ A. anacominus extract 1000 f ■ Salicylic acid 40? ■ Glycerin
801' ■ Prepare 4 fl of lactic acid and add 40? of salicylic acid. and Glycerin 80F are mixed well, and added to this mixture is Tororo mallow extract 1100 (
Mix l. Lactic acid 402 is added to this mixture (liquid) and mixed. (Hereinafter, this mixed liquid will be referred to as a "paste composition.") Store this paste composition in a cool, dark place or in a refrigerator. In such cases, this pasty composition may be used for a long period of time (
In experiments, rot and viscosity reduction have been prevented even after 5 years have passed. ) can be preserved (prevented from rotting) and prevented from decreasing in viscosity.

In other words, it was found that salicylic acid, glycerin, and lactic acid are effective in preventing the spoilage and viscosity reduction of neri (extract of A. spp. 3% to 5% salicylic acid, 7% to 9% glycerin, 3% lactic acid.
It has been found that the above measures are most effective when the amount is between 5% and 5%. The amount of salicylic acid and lactic acid is 5%.
It goes without saying that the above amounts may be used, and it goes without saying that increasing the amount will not affect spoilage prevention or viscosity.

The paste-like composition extracted and mixed in the above manner does not rot and its viscosity does not decrease, but its components are completely different from Neri, which has traditionally been used for washi papermaking (salicylic acid,
Contains a mixture of glycerin and lactic acid. ), and the use of activated carbon almost eliminates the unique odor of A. japonica, increasing its value as a base for pharmaceutical preparations.

Accordingly, the present invention provides an athlete's foot medicine prepared by using this paste composition as a base and mixing stearic acid, potassium carbonate, myristic acid, aliphatic higher alcohol, glycerin, bentonite, and lanolin.

Next, an example of a method for producing an athlete's foot medicine by mixing each of the above-mentioned components into a base (paste-like composition) is shown. The mixtures and their blending amounts are as shown in the following table.

Stearic acid, myristic acid, aliphatic higher alcohol, and glycerin listed in the table above are mixed and dissolved by heating, and to this solution, a potassium carbonate solution prepared by dissolving potassium carbonate in water is added little by little to obtain an aliphatic potassium carbonate salt. and mix this aliphatic potassium carbonate with a base.

Next, add bentonite to this mixture and knead at ℃.Furthermore, add lanolin in a hot bath and knead.

In such a case, the paste-like athlete's foot medicine of the present invention can be obtained.

In addition, stearic acid and myristic acid are both fat 11.J
fatty acids, and when only one is used, 402 (4
0% amount) may be used.

Potassium carbonate is used to neutralize the acidic salicylic acid and lactic acid in the base and make the entire product weakly acidic, so it is increased or decreased depending on the amount of salicylic acid and lactic acid in the base.

Athlete's foot medicine consists of the above combinations. Salicylic acid is a bactericidal agent and is irritating to the skin, but lactic acid relieves this, lanolin protects the affected skin surface, and bentonite is Since the molasses has an extremely strong viscosity, it acts to suppress it to some extent and also acts to alleviate the irritating effect on the skin debris on each side.

Furthermore, glycerin is what makes the main principle applicable to fake surfaces. In addition, stearic acid, myristic acid, and aliphatic higher alcohol are basically used to form a cream to make it easier to apply, so the amount of blending may be changed depending on whether you want a cream-like finish for hard or soft skin. It is possible. The paste-like athlete's foot medicine thus produced acts gently on the affected skin without irritating the affected area, and has the effect of reliably curing athlete's foot.

Claims (1)

[Claims] The base is a paste composition made by mixing salicylic acid, glycerin, and lactic acid with a hollyhock extract obtained by deodorizing with activated carbon, and a liquid in which fatty acids, aliphatic higher alcohols, and glycerin are mixed and heated to dissolve in this base. Add an aqueous solution of potassium carbonate to make aliphatic potassium carbonate salt and this aliphatic potassium carbonate salt 1
2 parts of the base agent, and then knead with bentonite added in an amount of 7% to 10% of the total mixture,
Furthermore, a paste-like athlete's foot medicine is prepared by adding 5% to 10% of lanolin and kneading it.