JPS6187695A - ＧｎＲＨ拮抗物質 - Google Patents

ＧｎＲＨ拮抗物質

Info

Publication number
JPS6187695A
JPS6187695A JP60197532A JP19753285A JPS6187695A JP S6187695 A JPS6187695 A JP S6187695A JP 60197532 A JP60197532 A JP 60197532A JP 19753285 A JP19753285 A JP 19753285A JP S6187695 A JPS6187695 A JP S6187695A
Authority
JP
Japan
Prior art keywords
group
phe
peptide
arg
trp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP60197532A
Other languages
English (en)
Japanese (ja)
Inventor
ワイリー・ウオーカー・ベール・ジユニア
ジヤン・エドワール・フレデリツク・リベール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Publication of JPS6187695A publication Critical patent/JPS6187695A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP60197532A 1984-09-07 1985-09-06 ＧｎＲＨ拮抗物質 Pending JPS6187695A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US648637 1984-09-07
US06/648,637 US4565804A (en) 1984-09-07 1984-09-07 GnRH Antagonists VI

Publications (1)

Publication Number Publication Date
JPS6187695A true JPS6187695A (ja) 1986-05-06

Family

ID=24601597

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60197532A Pending JPS6187695A (ja) 1984-09-07 1985-09-06 ＧｎＲＨ拮抗物質

Country Status (12)

Country Link
US (1) US4565804A (US07816562-20101019-C00012.png)
EP (1) EP0175506A3 (US07816562-20101019-C00012.png)
JP (1) JPS6187695A (US07816562-20101019-C00012.png)
KR (1) KR860002528A (US07816562-20101019-C00012.png)
AU (1) AU4687985A (US07816562-20101019-C00012.png)
DD (1) DD248365A5 (US07816562-20101019-C00012.png)
DK (1) DK407985A (US07816562-20101019-C00012.png)
ES (1) ES8900167A1 (US07816562-20101019-C00012.png)
GR (1) GR852148B (US07816562-20101019-C00012.png)
HU (1) HUT40144A (US07816562-20101019-C00012.png)
PH (1) PH21284A (US07816562-20101019-C00012.png)
ZA (1) ZA856449B (US07816562-20101019-C00012.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU193093B (en) * 1985-04-16 1987-08-28 Innofinance Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation
US4705778A (en) * 1985-10-22 1987-11-10 Sri International Orally active LHRH analogs
US4888427A (en) * 1987-04-07 1989-12-19 University Of Florida Amino acids containing dihydropyridine ring systems for site-specific delivery of peptides to the brain
US5079366A (en) * 1987-04-07 1992-01-07 University Of Florida Quarternary pyridinium salts
US4800191A (en) * 1987-07-17 1989-01-24 Schally Andrew Victor LHRH antagonists
US4935491A (en) * 1987-08-24 1990-06-19 Board Of Regents, The University Of Texas System Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine
US5171835A (en) * 1988-10-21 1992-12-15 The Administrators Of The Tulane Educational Fund LHRH antagonists
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5084443A (en) * 1989-12-04 1992-01-28 Biomeasure, Inc. Promoting expression of acetylcholine receptors with lhrh antagonist
US5064939A (en) * 1990-02-06 1991-11-12 The Salk Institute For Biological Studies Cyclic gnrh antagonists
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5656727A (en) * 1992-09-15 1997-08-12 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
US5480969A (en) * 1992-09-15 1996-01-02 The Administrators Of The Tulane Educational Fund Antagonists of LHRH
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
US5696230A (en) * 1994-08-31 1997-12-09 The Board Of Regents Of The University Of Nebraska High-affinity response-selective C-terminal analogs of C5a anaphylatoxin
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
EP0882736A1 (en) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. LH-RH peptide analogues, their uses and pharmaceutical compositions containing them
CA2322444A1 (en) 1998-03-05 1999-09-10 Agouron Pharmaceuticals, Inc. Non-peptide gnrh agents
US6455499B1 (en) 1999-02-23 2002-09-24 Indiana University Foundation Methods for treating disorders associated with LHRH activity
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
US6598784B2 (en) * 2000-12-20 2003-07-29 Meadwestvaco Packaging Syatens, Llc Beverage carton with strap type carrying handle
EP2228388A1 (en) * 2001-04-18 2010-09-15 The Open University Protected Arg-Glu-Arg polypeptides and uses thereof
US7491702B2 (en) * 2001-04-18 2009-02-17 The Open University Polypeptides related to amyloid precursor protein, pharmaceutical compositions thereof, and methods of treatment using the same
US7622446B2 (en) 2001-04-18 2009-11-24 The Open University Polypeptides, derivatives and uses thereof
WO2008067086A2 (en) 2006-10-24 2008-06-05 Repros Therapeutics Inc. Compositions and methods for suppressing endometrial proliferation
US20220257695A1 (en) 2017-03-31 2022-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) A gnrh antagonist for use in the treatment of a women affected with polycystic ovary syndrome

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
US4317815A (en) * 1979-06-13 1982-03-02 Coy David Howard LH-RH Antagonists
US4341767A (en) * 1980-10-06 1982-07-27 Syntex Inc. Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
US4481190A (en) * 1982-12-21 1984-11-06 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
DE3467173D1 (en) * 1983-08-16 1987-12-10 Akzo Nv Lh- rh antagonists

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US6863891B2 (en) 1993-02-19 2005-03-08 Zentaris Ag Oligopeptide lyophilisate, their preparation and use
US6867191B2 (en) 1993-02-19 2005-03-15 Zentaris Gmbh Preparation and use of oligopeptide lyophilisate for gonad protection

Also Published As

Publication number Publication date
DK407985A (da) 1986-04-09
KR860002528A (ko) 1986-04-26
EP0175506A2 (en) 1986-03-26
AU4687985A (en) 1986-03-13
ES8900167A1 (es) 1988-04-16
GR852148B (US07816562-20101019-C00012.png) 1986-01-08
US4565804A (en) 1986-01-21
ZA856449B (en) 1986-04-30
PH21284A (en) 1987-09-28
HUT40144A (en) 1986-11-28
ES546761A0 (es) 1988-04-16
DK407985D0 (da) 1985-09-06
EP0175506A3 (en) 1987-10-14
DD248365A5 (de) 1987-08-05

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