JPS6140652B2 - - Google Patents

Info

Publication number
JPS6140652B2
JPS6140652B2 JP57182666A JP18266682A JPS6140652B2 JP S6140652 B2 JPS6140652 B2 JP S6140652B2 JP 57182666 A JP57182666 A JP 57182666A JP 18266682 A JP18266682 A JP 18266682A JP S6140652 B2 JPS6140652 B2 JP S6140652B2
Authority
JP
Japan
Prior art keywords
technetium
idp
imidodiphosphonate
complex
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP57182666A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58113137A (ja
Inventor
Saburamanian Goparu
Girumoa Matsukafuii Jon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp
Original Assignee
Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp filed Critical Research Corp
Publication of JPS58113137A publication Critical patent/JPS58113137A/ja
Publication of JPS6140652B2 publication Critical patent/JPS6140652B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57182666A 1975-05-30 1982-10-18 動物用骨親和性組成物 Granted JPS58113137A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/582,176 US3974268A (en) 1975-05-30 1975-05-30 Bone-seeking technetium-99m imidodiphosphonate complex
US582176 1975-05-30

Publications (2)

Publication Number Publication Date
JPS58113137A JPS58113137A (ja) 1983-07-05
JPS6140652B2 true JPS6140652B2 (en, 2012) 1986-09-10

Family

ID=24328131

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50129763A Expired JPS5835487B2 (ja) 1975-05-30 1975-10-28 テクネチウム−９９↓ｍ−イミドジホスホネ−トコンプレツクスの調製法
JP57182666A Granted JPS58113137A (ja) 1975-05-30 1982-10-18 動物用骨親和性組成物

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP50129763A Expired JPS5835487B2 (ja) 1975-05-30 1975-10-28 テクネチウム−９９↓ｍ−イミドジホスホネ−トコンプレツクスの調製法

Country Status (5)

Country Link
US (1) US3974268A (en, 2012)
JP (2) JPS5835487B2 (en, 2012)
CA (1) CA1069914A (en, 2012)
DE (2) DE2547376C2 (en, 2012)
GB (2) GB1510664A (en, 2012)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0255064U (en, 2012) * 1988-10-12 1990-04-20
JPH031063A (ja) * 1989-05-26 1991-01-07 Toyo Eng Works Ltd 人工降雪装置

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3974268A (en) * 1975-05-30 1976-08-10 Research Corporation Bone-seeking technetium-99m imidodiphosphonate complex
DE2543350C2 (de) * 1975-09-29 1984-10-11 Henkel KGaA, 4000 Düsseldorf Präparate zur Herstellung von ↑9↑↑9↑↑m↑ Technetium-Radiodiagnostika
DE2543349C2 (de) * 1975-09-29 1984-05-10 Henkel KGaA, 4000 Düsseldorf Preaparate zur herstellung von99m technetium-radiagnostica
CA1078731A (en) * 1976-12-16 1980-06-03 Charles E. Frosst And Co. Skeletal imaging kit utilizing triethylene tetramine hexa (methylene phosphonic acid)
US4897255A (en) * 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
US5175343A (en) * 1985-01-14 1992-12-29 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
JP2785025B2 (ja) * 1985-03-19 1998-08-13 ランデル・エル・ミルズ 診断と選択的組織壊死を与える装置
JPS61282931A (ja) * 1985-06-10 1986-12-13 Hitachi Ltd 初期マイクロプログラム・ロ−ド方式
US5202451A (en) * 1988-02-17 1993-04-13 Neorx Corporation Anchimeric radiometal chelating compounds
US5089249A (en) * 1988-06-10 1992-02-18 Neorx Corporation Conjugates for bone imaging and bone cancer therapy
US5202109A (en) * 1988-06-10 1993-04-13 Neorx Corporation Conjugates for bone imaging and bone cancer therapy
US5192526A (en) * 1989-05-02 1993-03-09 Mallinckrodt Medical, Inc. Kit for preparation of rhenium therapeutic agents for bone cancer without purification
JP2003501488A (ja) * 1999-06-11 2003-01-14 ネオルックス コーポレイション 骨髄抑制のための高投与量放射性核種錯体
US7094885B2 (en) * 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
US6548042B2 (en) * 2000-08-07 2003-04-15 Arstad Erik Bis-phosphonate compounds
WO2002062398A2 (en) 2001-01-08 2002-08-15 Neorx Corporation Radioactively labelled conjugates of phosphonates
US6776977B2 (en) * 2001-01-09 2004-08-17 Bristol-Myers Squibb Pharma Company Polypodal chelants for metallopharmaceuticals
WO2021032784A1 (en) 2019-08-19 2021-02-25 Nuclear Research And Consultancy Group Platinum isotope combined with bone-targeting agents for use in anticancer drugs

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125412A (en) * 1964-03-17 Process ok the manufacture of alkali
DE1015777B (de) * 1956-10-16 1957-09-19 Benckiser Gmbh Joh A Verfahren zur Herstellung von Phosphamprodukten
US3735001A (en) * 1972-05-24 1973-05-22 Atomic Energy Commission Technetium bone scanning medium
US3974268A (en) * 1975-05-30 1976-08-10 Research Corporation Bone-seeking technetium-99m imidodiphosphonate complex

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0255064U (en, 2012) * 1988-10-12 1990-04-20
JPH031063A (ja) * 1989-05-26 1991-01-07 Toyo Eng Works Ltd 人工降雪装置

Also Published As

Publication number Publication date
JPS51144737A (en) 1976-12-13
US3974268A (en) 1976-08-10
GB1510665A (en) 1978-05-10
CA1069914A (en) 1980-01-15
DE2547376C2 (de) 1987-01-29
DE2560627C2 (en, 2012) 1987-08-06
JPS5835487B2 (ja) 1983-08-03
JPS58113137A (ja) 1983-07-05
GB1510664A (en) 1978-05-10
DE2547376A1 (de) 1976-12-09

Similar Documents

Publication Publication Date Title
JPS6140652B2 (en, 2012)
Subramanian et al. 99mTc-labeled polyphosphate as a skeletal imaging agent
US4115541A (en) Bone-seeking technetium-99m complex
US3989730A (en) Bone-seeking technetium-99m complex
Fliegel et al. 99mTc-tetracycline as a kidney and gallbladder imaging agent
US4897254A (en) Radioactive compositions for the treatment of calcific tumors
Reissig et al. The impact of barium isotopes in radiopharmacy and nuclear medicine–From past to presence
US5853695A (en) Method for palliation of pain in human bone cancer using therapeutic tin-117m compositions
US4032625A (en) Bone-seeking technetium-99m complex
JPS6133808B2 (en, 2012)
DE69828779T2 (de) Radionukleiide assoziierte nukleotid-polyphosphate zur bilddarstellung von tumoren
JPS62132892A (ja) 治療上有効な複合体、その製法、および医薬組成物
US4017595A (en) Bone-seeking indium-113m or indium-111 organic phosphonate complexes
US4515766A (en) Labeled phosphonic acid compositions for investigations of in vivo deposits of calcium
CA2411577C (en) Stabiliser for radiopharmaceuticals
de Murphy et al. Radiopharmacokinetic data for 99mTc-ABP—a new radiopharmaceutical for bone scanning: comparison with 99mTc-MDP
JPWO2008056481A1 (ja) 放射性画像診断剤
AU2001264133A1 (en) Stabiliser for radiopharmaceuticals
JPH0559894B2 (en, 2012)
CN119630434A (zh) 用于靶向分子成像的铜的放射性药物组合物
CA1071834A (en) Stannous imidodiphosphonate complex
Castronovo Jr et al. Iodine-125 labeled phenylphosphonic acid: a new radiopharmaceutical for long-term investigations of the skeleton
JP2864448B2 (ja) 安定な放射性テクネチウム標識診断用組成物
Clements et al. Iodinated cholylglycyltyrosine: A new agent for hepatobiliary imaging
Rodriguez et al. 153Sm-EDTMP