JPS61291507A - Rodent repellent - Google Patents

Abstract

PURPOSE:To obtain the titled agent effective to give a rodent with disagreeable feeling and repel the rodent without killing by using shikimic acid, etc., as a main component, mixing the component with ethyl acetate, etc., used as subsidiary component and a mustard glycoside having catalytic action, aging the mixture, separating into solid and liquid, and adding HANSHO liquid, formalin, etc., to the liquid extract. CONSTITUTION:Shikimic acid, toxin, amino acid and KUJIN (root of Sophora angustifolia) alkaloid are used as the main components, mixed with subsidiary components composed of water, ethanol, acetic acid and ethyl acetate and with mustard glucoside acting as a catalyst, and the mixture is aged. After aging, the mixture is separated into solid and liquid e.g. by centrifugal separator, etc., and the liquid component is collected. The extracted liquid is mixed with HANSHO liquid, SHIKIMI (Illicium anisatum L.) liquid, chrysanthemum liquid, raw starfish liquid, formalin, pyridine and ethanol. The activity can be further improved by the addition of orange oil. Rodent is attracted by the evaporated active components such as ethyl acetate, formalin, etc., and the nerve is unbalanced by the absorption of the main components such as shikimic acid, etc., to make the rodent dislike the odor.

Description

[Detailed description of the invention] (b) Industrial application field The present invention relates to a drug that is feared by mice.

(b) Conventional technology Conventionally, rats have a very strong reproductive capacity and give birth to children several times a year, and if we slack off on exterminating them, they quickly infest the area, causing endless damage.

For example, rats prefer to eat rice and wheat, which is our staple food, and they cause enormous damage to kitchens and granaries.They also gnaw potatoes and destroy vegetables in the fields, and sometimes destroy chicks in poultry farms overnight. In addition, if field mice living in forest areas do not gnaw on something even when they are not hungry, their incisors will grow too long and cause wear problems. These rats can cause a tremendous amount of damage, causing gas to leak by chewing through them, or by chewing over power lines, exposing wires and even causing fires.

Therefore, a wide variety of rodenticides have been developed to prevent the above-mentioned rodent damage, and these rodenticides are mainly mixed with the food that rodents prefer, creating so-called poisonous bait and placing it in passageways and holes. It poisons people to death by feeding them. Compounds conventionally used as such rodenticides include inorganic salts such as yellow phosphorus, nitrous acid, thallium, and barium, as well as organic compounds such as strychnine, and plant-based compounds such as Red Skill, which are used to control field mice. The field mouse typhoid bacillus has been used since the end of the Meiji era, but its use was banned in 1948 due to hygiene reasons. After World War II, synthetic organic rodenticides such as Antu, sodium monofluoroacetate, Warharin, Kastrix, and Muritan were put into practical use one after another, resulting in many developments in the scientific control of rats. Among them,
Marine compounds such as Warharin have a completely new rodenticidal effect, making use of their anticoagulant properties and causing chronic poisoning symptoms and lethality when administered continuously to rats.

(c) Problems to be solved by the invention However, these rodenticides are not only highly toxic to rats, but also highly toxic to humans and livestock, so careful attention is required when handling them. It was not something that could be easily used at home.

This is because most of the drugs are processed from seeds and starchy powders that mice like, and are designated as non-medicinal poisons under the Poisonous and Deleterious Substances Control Law, and sodium monofluoroacetate, Kastrix, and Muritan are classified as specified poisons. This is because the handling standard has been established and measures have been taken to restrict its use.

Therefore, it is desirable for rodenticides to be ones that are not repelled by rats, do not cause drug resistance, have a calm lethal state and do not cause alarm, and have low toxicity to humans and livestock. Each has its advantages and disadvantages, and none of them are at a satisfactory stage yet.

(d) Means for solving the problem Therefore, in the present invention, the main components of shikimic acid, toxin,
Amino acids, bitter ginseng alkaloids, and water as a subcomponent,
After mixing and aging ethanol, acetic acid, and ethyl acetate with mustard glycosides that act as a catalyst, solid-liquid separation is performed using a centrifuge, etc., and only the liquid portion is extracted. It is an object of the present invention to provide a mouse repellent which is made by mixing Shikimi liquid, chrysanthemum liquid, raw starfish liquid, formalin, pyridine, and ethanol.

(E) Action When using a rodent repellent, place the rodent repellent in a designated container in a place where rodents are likely to be present. The components shikimic acid, toxins, amino acids, and bitter ginseng alkaloids chemically bond through the subcomponents water, ethanol, acetic acid, ethyl acetate, and mustard glycosides, and are absorbed into the bodies of small animals, especially mice. Furthermore, this active ingredient is volatilized by formalin, pyridine, and ethanol, and the odor of ethyl acetate induces mice to absorb this volatilized active ingredient in their respiratory tract. When absorbed from the system, the nervous system becomes temporarily unbalanced, and the mouse runs away with its unbalanced nerves, but as it repeats this action, it remembers that this odor upsets the nervous balance. , they begin to avoid this odor and eventually disappear.

(f) Effects According to the present invention, the idea is changed from the conventional idea of killing mice to giving a sense of FR fear to mice, and moreover, it is possible to create a mouse v that can achieve the same purpose.
Because rodenticides can be manufactured, there have been disadvantages and problems with rodenticides, including their effects on humans and livestock, inconvenience in handling, difficulty in decomposing rodent carcasses, and the possibility of bacterial growth caused by rotting carcasses. It is an ideal mouse extermination method that can completely avoid and solve breeding, etc., and will ultimately eliminate all the mice, even those with a strong breeding ability, in order to guide the mice with scent and give them a sense of awe. It is effective.

(g) Example To explain in detail the example of the present invention, the rat repellent contains shikimic acid, toxin, amino acid, and bitter ginseng alkaloid as main components, and water, ethanol, acetic acid, and acetic acid as subcomponents. After mixing and aging ethyl and mustard glycosides that act as a catalyst, solid-liquid separation is performed using a centrifuge, etc.
It is made by extracting only the liquid component and mixing the same extract with Pan sapiensis, shikimi juice, chrysanthemum juice, raw starfish liquid, formalin, pyridine, ethanol, and orange oil.

In other words, shikimic acid is the basic ingredient that makes the active ingredient of the rodent repellent, and is characterized by being extracted from Japanese cypress, which is used as a medicinal herb.
and 12 ka of 30% concentration ethanol are put into a predetermined first container in this order, maintained at an appropriate temperature of 30° C. to 35° C., and aged for a certain period of time.

In addition, toxins and amino acids are the raw materials necessary to make the active ingredients of the drug, and are extracted from dried crown-of-thorns starfish. Into a second container prepared separately from the above, put 157 dried starfish, 67 volumes of water, 358 kg of 30% concentration ethanol, and 20 ka of acetic acid in this order, and heat at a suitable ripening temperature of 30°C to 35°C. It is marinated and aged for a certain period of time.

At this time, water functions to extract components from the blended raw materials, ethanol functions to extract toxins and amino acids, and acetic acid functions to extract shikimic acid and bitter ginseng calcium chloride after ripening. When mixed with toxin, amino acid, and amino acid, these have the function of making it easier to form a compound.

In addition, mustard glycosides that have a catalytic effect were prepared by putting 50 kg of wet water and 150 kg of 30% ethanol (in this order) into a third container different from the one above, and heating it for 130 kg.
It is aged for a certain period of time at a temperature of 35°C to 35°C.

The raw materials in the first, second and third containers above may vary depending on the climate.
One month in the summer (Monday to September), and one month in the autumn (October to March)
It is steeped for three months in the winter and for two months in the spring from April to May, until it is half fermented. At this time, the inside of each container is stirred every day to prevent solid-liquid separation. This is to prevent it from happening.

After the above soaking period has passed, the first, second,
A total of 817 kg of raw materials in the third container were placed in one stirrer, 68 kg of bitter ginseng was added and stirred for about 10 minutes, and finally 8 k (l) of ethyl acetate was added and stirred for about 10 minutes.

At this time, bitter ginseng alkaloids are extracted from bitter ginseng, which is used as a medicinal herb by cutting and drying Kurara, and the bitter ginseng alkaloids act on shikimic acid with toxins and amino acids to form components. Furthermore, ethyl acetate effectively exerts the ingredients and acts to induce small animals.

Thereafter, the 893 ka of mixed and stirred raw materials were separated into solid and liquid using a centrifuge, etc., and only the liquid portion was 683 ka (1 ka).
(76.5%) extracted and added to 60 kg of the same extract, 9 to wet 30, 30 kc+ of Shikimi liquid, 5 kg of chrysanthemum liquid which is an extract extracted from chrysanthemum leaves, 5 kg of raw starfish liquid, 5 kg of formacin, 0 pyridine. A rodent repellent is commercialized by mixing 14kc+ of 95% ethanol and adding 5g of orange oil per 120kg of the mixture when filling the mixture into a predetermined container.

At this time, mustard glycosides that have a catalytic effect are obtained from wet plants, shikimic acid is obtained from shikimi juice, and chrysanthemum arum and M, which strengthen the active ingredients, are obtained from raw starfish. Toxins and amino acids are extracted, and these are mixed in a semi-fermented state. Formacin, pyridine, and ethanol all work to enhance the active ingredients, and orange oil. Orange essential oil, which is an ingredient, strengthens the active ingredients.

Next, the shikimate pathway will be explained. In other words, shikimic acid is produced by erythrose-4-phosphate and phosphoenolpyruvate obtained from triose phosphate, which is a product of photosynthesis, and by ring closure of the C7 phosphate ester of 2-ketoaldonic acid produced by these reactions. It is a thing,
Chorismic acid is produced by the reaction with phosphoenolpyruvate from the same shikimic acid, and tryptophan is biosynthesized from the same chorismic acid via anthranilic acid with the involvement of serine. and tyrosine are each biosynthesized.

As mentioned above, in the shikimic acid pathway, amino acids are formed from shikimic acid, but using the reaction form, shikimic acid incorporates the amino acid with toshikin produced by fermentation from starfish, and then the bitter starch alkaloid It constitutes a molecule with matrine attached. Its molecules include safrole, cineole,
Additionally, Shikimi essential oil, whose main component is eugenol, is added to give it a fragrance.

Therefore, if a rodent repellent manufactured mainly from medicinal herbs is placed in a designated location, the ethyl acetate, formalin, pyridine, and ethanol that make up the rodent repellent will volatilize the active ingredients. Ethyl acetate guides mice to the ground where the aphobic agent is located, and the induced mice absorb the active ingredients of shikimic acid, toxins, amino acids, and bitter ginseng alkaloid compounds through their respiratory system. , amino acid metabolism in the body is suppressed, resulting in an imbalanced nervous system. Therefore, the mouse temporarily escapes to memorize the neural imbalance, but as it repeats this action, it becomes physiologically averse to the odor emitted by the above-mentioned fear-repelling agent, and It makes you stay away from the place.

Furthermore, the components released by the rodent repellent have no effect on humans or animals, and rather function as fragrances and deodorants.

In addition, when all the volatile components of rat repellent are volatilized, only the solid content remains, but because bitter ginseng alkaloids, toxins, etc. remain in the solid content,
When a cockroach comes into contact with the solid material, the cockroach's nerves are paralyzed, and it also has an insecticidal effect on cockroaches.

In addition, the rat repellent according to the present invention is not limited to rats;
It can be applied to small animals in general, and is particularly effective against mice, which are problematic.

[Brief explanation of drawings]

The figure is an explanatory diagram of the shikimate pathway.

Claims (1)

[Claims] 1) Main ingredients: shikimic acid, toxin, amino acid, and
After mixing and aging bitter ginseng alkaloids, subcomponents of water, ethanol, acetic acid, and ethyl acetate, and mustard glycosides that act as catalysts, solid-liquid separation is performed using a centrifuge, etc., and only the liquid component is extracted. A rodent repellent is prepared by mixing the same extract with Pan sapiensis liquid, Shikimi liquid, chrysanthemum liquid, raw starfish liquid, formalin, pyridine, and ethanol.