JPS61251605A - Cosmetic - Google Patents

Abstract

PURPOSE:A cosmetic, containing soluble collagen and a derivative thereof and lecithin in combination, having improved humectant properties and feeling of use without stickiness with little change in viscosity or hardness with time. CONSTITUTION:A cosmetic containing one or two or more of soluble collagens, e.g. obtained by hydrolyzing collagen which is one of hard proteins constituting principal components of connective tissues of bones, cartilages, sinews, fish scale, etc., and preferably prepared by hydrolyzing the collagen with an acid, alkali or enzyme, and a derivative thereof and one or more of lecithins, e.g. lecithin extracted from egg yolk and soybeans. The amount of the collagens is 0.01-2wt%, particularly 0.02-1.5wt% based on the total amount of the cosmetic and the amount of the lecithins is 0.01-5wt%, preferably 0.05-3wt% based on the total amount of the cosmetic. EFFECT:Good stability and safety.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention relates to a cosmetic that has an excellent moisturizing effect, has a non-sticky feel during use, and exhibits little change in viscosity or hardness over time. - [Prior Art] Maintaining skin moisture within an appropriate range is extremely important from the perspective of skin health, and many cosmetics are available for the purpose of moisturizing.

Research into substances involved in skin moisturization is progressing, and many moisturizers are now in use, including polyhydric alcohols such as propylene glycol and sorbitol.

Under these circumstances, collagen has recently been attracting attention. Collagen is a protein that exists in abundance in the dermis of the skin, connective tissue, bones, etc. Skin aging progresses as tissue aggregation occurs in the dermis. In other words, collagen, which initially existed in the form of fibers between cells in tissues, increases the degree of bonding within or between molecules as we age, and the fibers become thicker and reticular. As the collagen fibers become reticulated, the water-binding ability of the collagen fibers decreases, resulting in loss of swelling and elasticity. Through this process, the skin hardens, wrinkles increase, and at the same time, it loses its water-retaining ability and ages.

Due to the above-mentioned circumstances, attempts have been made to incorporate collagen, particularly soluble collagen, into skin cosmetics for the purpose of restoring the elasticity of the skin and making it fresh.

However, although soluble collagen has an excellent moisturizing effect, it has a strong sticky feel when used. Also,
Systems containing collagen have the drawback of increasing viscosity and hardness over time, and in some cases causing gelation.

[Problems to be Solved by the Invention] In view of the above circumstances, the inventors of the present invention conducted intensive studies with the aim of suppressing the stickiness of soluble collagen and preventing increases in the viscosity and hardness of the system. Surprisingly, they discovered that when lecithin is added in combination with collagen, the above problems are not only solved, but also the moisturizing effect of soluble collagen is further enhanced. The present invention is based on the above findings.

[Means for Solving the Problems] That is, the present invention is a cosmetic composition containing one or more types of soluble collagen and derivatives thereof, and one or more types of lecithin.

The soluble collagen used in the present invention exists in bones, cartilage, torso, skin, fish scales, etc. As mentioned above, collagen, which is a hard protein that is the main component of connective tissue, is
Hydrolyzed with alkali or enzymes, etc. Among these, those made solubilized by protease treatment (for example, see Japanese Patent Application Laid-Open No. 110336/1982) are free from allergy as telopeptide has been removed. preferable. A soluble collagen derivative obtained by treating soluble collagen with a polybasic acid such as succinic acid is also preferable because it has good hydrophilicity and can be dissolved well in the system regardless of the pH of the system. Naturally, soluble succinated collagen obtained by treating soluble collagen obtained by protease treatment with, for example, succinic acid is optimal for use in cosmetics.

In the present invention, one or more types of soluble collagen and derivatives thereof are arbitrarily selected and used. The blending amount is 0.01 to 2% by weight based on the total amount of cosmetics, preferably 0.
．． 02 to 1.5% by weight. If it is less than 0.01% by weight, the moisturizing effect will be poor and the stickiness will be low. If it exceeds 2% by weight, it will become sticky and viscous even when used in combination with lecithin.
It becomes difficult to suppress the increase in hardness.

The lecithin used in the present invention is a phospholipid that is widely distributed in living organisms such as animals, plants, and microorganisms, and includes lecithin extracted from egg yolks and soybeans, as well as lecithin or hydrogenated products obtained by further purifying these. Including. In the present invention, one or more of the above lecithins are appropriately selected and used.

The amount of lecithin blended is 0.01 to 5% by weight, preferably 0.05 to 3% by weight based on the total amount of the cosmetic. If it is less than 0.01% by weight, the effects of the present invention will not be exhibited.

In addition to the above-mentioned essential ingredients, the cosmetics of the present invention contain polyhydric alcohols, oily ingredients, ultraviolet absorbers, lower alcohols, surfactants, preservatives, colorants, powders, and fragrances commonly used in cosmetics. Other components such as , drugs, etc. can be appropriately added within a range that does not impair the effects of the present invention.

Examples of polyhydric alcohols, oily components, ultraviolet absorbers, lower alcohols, and surfactants are as follows.

Polyhydric alcohols: ethylene glycol, polyethylene glycol, propylene glycol, 1,3-butylene glycol, 1,4-butylene glycol, dipropylene glycol, polyglycerin such as glycerin, diglycerin, triglycerin, tetraglycerin, glucose, maltose, Multidose, sucrose, fructose, xylitose, sorbitol, maltotriose, threitol, erythritol, etc.

Oily ingredients: beef tallow, squalane, olive oil, evening primrose oil,
Animal and vegetable oils such as rice bran oil, hydrocarbons, mineral oils such as liquid paraffin, ester oils such as isopropyl myristate, pentaerythritol-tetra-2-ethylhexanoate, silicone oils such as methylphenyl silicone and dimethyl silicone, 2- Octyldodecanol, 2
-Alcohols such as decyltetradecanol, oleyl alcohol, cetyl alcohol, fatty acids such as behenic acid, oleic acid, isostearic acid, and vitamins such as tamin A, vitamin E, vitamin D1, and derivatives thereof.

Ultraviolet absorber; para-aminobenzoic acid, para-methoxycinnamate-2-ethoxyethyl, para-methoxycinnamate isopropyl, butylmethoxybenzoylmethane, glyceryl-mono-2-ethylhexanoyl-di-paramethoxybenzophenone, digaloyl triole ate, 2-2'-dihydroxy-4-methoxybenzophenone, ethyl-4-bishydroxypropylaminobezoate, 2
-Ethylhexyl-2-cyano-3,3"-diphenylacrylate, ethylhexyl paramethoxycinnamate, 2-ethylhexyl salicylate, glyceryl paraaminobenzoate, homomethyl salicylate, methyl orthoaminobenzoate, 2-hydroxy-4-methoxybenzophenone , amyl-para-dimethylaminobenzoate, 2-phenylbenzimidazole-5-sulfonic acid, 2-hydroxy-4-methoxybenzophenone-5
-Sulfonic acid, etc.

Lower alcohols: ethyl alcohol, propyl alcohol, isopropyl alcohol, butyl alcohol, isobutyl alcohol, etc.

Surfactant; polyoxyethylene [hereinafter abbreviated as POE-] POE-branched alkyl ether such as octyldodecyl alcohol, POE-2-decyltetradecyl alcohol, POE-oleyl alcohol ether, POE
- POE-alkyl ethers such as cetyl alcohol ether, sorbitan esters such as sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, POE-sorbitan monooleate,
POE-sorbitan monoisostearate), POf! −
POE-sorbitan esters such as sorbitan monorate, glycerin fatty acid esters such as glyceryl monooleate, glyceryl monostearate, glyceryl monomyristate, POE-glyceryl monooleate, POE-glyceryl monostearate), POE-
POE-glycerin fatty acid esters such as glyceryl monomyristate, POE-dihydrocholesterol ether, POE-hydrogenated castor oil, POE-hydrogenated castor oil fatty acid esters such as POE-hydrogenated castor oil isostearate, POE-octylphenol ether, etc.
Glycerol ethers such as OE-alkylaryl ether, glycerol monoisostearate, glycerol monomyristate, POt! - POE-glycerol ethers such as glycerol monoisostearate, POE-glycerol monomyristate, diglyceryl monostearate, decaglyceryl decastearate,
Nonionic surfactants such as polyglycerin fatty acid esters such as decaglyceryl decaisostearate and diglyceryl diisostearate, potassium of higher fatty acids such as myristic acid, stearic acid, palmitic acid, behenic acid, isostearic acid, and oleic acid. , sodium, jetanolamine, triethanolamine, salts of amino acids, etc., the above-mentioned alkali salts of ether carboxylic acids, salts of N-acylamino acids, N-acyl sarconates, higher alkyl sulfonates, etc., anionic surfactants, alkyl Cationic surfactants or amphoteric surfactants such as amine salts, polyamines, aminoalcohol fatty acid organic silicone resins, and alkyl quaternary ammonium salts.

Among the other components mentioned above, lower alcohols in particular have the effect of further suppressing the sticky feeling.

The anti-stickiness effect becomes especially noticeable when the amount is about 2M in the total amount of cosmetics, and it is easy to increase the amount up to 30 to 40% by weight in general cosmetics, taking into consideration the irritation to the skin and the stability of the dosage form. It is possible to mix it into

Further, the dosage form of the cosmetic of the present invention is arbitrary, and may include solubilized type,
It can be used as an emulsion or as a powder dispersion, and can be used in a wide range of applications, including basic cosmetics such as lotions, milky lotions, and creams, as well as makeup cosmetics such as foundations, and hair cosmetics. Among them, it shows its true value especially when applied to transparent or translucent lotions. This is because lotions are generally water-alcohol based and feel particularly sticky after use.

[Effects of the Invention] Although the cosmetic of the present invention contains one or more of soluble collagen and its derivatives and has an excellent moisturizing effect, it does not have the stickiness characteristic of soluble collagen or its derivatives, and has no moisturizing effect. The effect has also been enhanced.

Furthermore, increases in viscosity and hardness over time, which tend to occur due to the inclusion of soluble collagen, are suppressed to a very small extent. It is also an excellent cosmetic with good stability and safety.

[Example] Next, the present invention will be explained in more detail with reference to Examples. The present invention is not limited to this in any way.

Example 1 Nutritional cream (A) Soybean lecithin 0.5 Cetanol 5 Stearic acid 3 Vaseline 7 Squalane 10 Isopropyl myristate 2 Glyceryl monostearate 3 Ethylparaben 0.2 Fragrance
0.2 (B) Soluble succinated collagen (protease treatment) 0.5 (Can you identify the substance with just this?) Propylene glycol 2 Potassium hydroxide 0.2 Purified water
Residue (manufacturing method) Oil phase part of A and B
After heating and dissolving the aqueous phases, the oil phase is mixed into the aqueous phase and emulsified using an emulsifying machine. The mixture was then cooled to a final temperature of 30° C. using a heat exchanger to obtain cream.

Example 2 Nutritional cream (A) Soybean lecithin 0.05 Cetanol 5 Stearic acid 3 Vaseline 7 Squalane 10 Isopropyl myristate 2 Glyceryl monostearate 3 Ethylparaben 0.2 Fragrance
0.2 (B) Soluble succinated collagen (protease treatment) 0.5 Propylene glycol 2 Potassium hydroxide 0.2 Purified water
Residue (manufacturing method) According to Example 1.

Comparative example 1 Nutritional cream (A) Setanol 5 Stearic acid 3 Vaseline 7 Squalane 10 Isopropyl myristate 2 Glyceryl monostearate 3 Ethylparaben 0.2 Fragrance
0.2 (B) Soluble succinated collagen (protease treatment) 0.5 Propylene glycol 2 Potassium hydroxide 0.2 Purified water
Residue (manufacturing method) According to Example 1.

Table 1 shows the test results for feel in use for Example 1.2 and Comparative Example 1.

This result shows that the combination of lecithin suppresses the stickiness of the soluble collagen derivative.

Table 1 (Judgment) A: Not sticky.

B: Slightly sticky, but there are problems with usability. This is a problem-free range.

C: Sticky.

D: Significantly sticky.

Next, Table 2 shows the test results regarding changes in hardness over time.
Shown below.

The hardness value is determined by storing the cream in a round glass bottle with a diameter of 5 cm in a constant temperature bath at 25 degrees, taking it out after a specified period of time, and measuring it with a card tension meter at 30 degrees Celsius.
8φ, 200g load).

Example 1 0.5 0.5 26 25
27 Example 2 0.05 0.5 27
28 2B Example 3 - 0.5 29
36 48 (blank below) Example 3 Cleansing cream (A) Egg yolk lecithin 0.5 cetanol 2 Piece wax 1 Solid paraffin 1 Stearic acid 2 Vaseline 10 Liquid paraffin 35 POE-Sorbitan stearate (8020 mol) 2.4 Diguacerin distear Rate 2.6 Probilparaben 0.3 Fragrance
0.3 (B) Soluble collagen (protease treatment) 1.5 Soluble succinated collagen (protease treatment) 0.5 Dipropylene glycol 5 Potassium hydroxide 0.08 Purified water
Residue (manufacturing method) According to Example 1.

Example 4 Nutritional emulsion (A) Hydrogenated lecithin 0.3, -Yuwax 1 Vaseline 2 Deodorized lanolin
1.5 jojoba oil
6 Cetyl isooctanoate 4 POE-2-octyldodecanol (8020 mol) 2.0 Ethylparaben 0.2 Butylparaben 0.1 Fragrance
0.3 (B) Soluble collagen (protease treatment) l Soluble succinated collagen (protease treatment) 1 Dipropylene glycol 2 Carboxymethyl polymer 0.2 L-arginine 0.2 Purified water
Residue (manufacturing method) According to Example 1.

Example 5 Foundation (A) Egg yolk lecithin 2 cetanol 3.5 stearic acid
2 Deodorized lanolin 5 Vaseline 2 Squalane
8 Glyceryl monooleate 2.5 POE-behenyl alcohol (8010 mol) 0.5 Ethylparaben 0.2 Butylparaben 0.2 (B) Soluble collagen
11.3-Butylene glycol
2 Mixed powder 15 Triethanolamine 0.25 Purified water
Residue (manufacturing method) According to Example 1.

Example 6 Lotion (A) Purified water Amount to make the total 100% Glycerin 2 Soluble succinated collagen (protease treatment') 0.011.3-Butylene glycol 10 (B) Ethanol
7 Purified lecithin
0.02POE-hydrogenated castor oil (8060 mol) 1
Fragrance 0.05 Methylparaben 0.1 (Production method) After uniformly dissolving the aqueous phase part of A and the alcohol part of B, add B to A.
were added and mixed to obtain a lotion.

Example 7 Aqueous essence (A) Purified water Amount to make the whole 100 1.3
-Butylene glycol 10 Maltitol
2 Soluble collagen (protease treatment) 0.2 Soluble succinated collagen (protease treatment) 0.1 Dipropylene glycol 5.0 Carboxymethyl polymer 0゜2 (B) Ethanol
5 egg yolk lecithin 0
．． IPOB - Hydrogenated castor oil (8060 moles) 1 Vitamin E acetate 0.1 Fragrance
0.05 oleyl alcohol
0.2 Methylparaben 0.
2 (C) Potassium hydroxide 0.1 (Production method) After uniformly dissolving the aqueous phase part of A and the alcohol part of B, add B to A to mix and solubilize, then add potassium hydroxide C. Obtained Essence.

Example 8 Day lotion (A) Purified water Amount to make the whole ioo 1.3
-Butylene glycol 10 Maltitol
2 Soluble collagen (protease treatment) 0.15 Soluble succinated collagen (protease treatment) 0.05 Carboxyvinyl polymer 0.15 (B) Ethanol
20 soy lecithin
O,0S2-ethylhexylparadimethylaminobezoate 1 Methylparaben 0. IPOB-Hydrogenated castor oil (EO60% /I/) 1.2 Trisodium edetate 1.2 Fragrance
O,0S(C) L-arginine
0.15 (Production method) According to Example 4.

Comparative Example 2 Nutritional Emulsion (A) Peace Wax 1 Vaseline
2 Deodorizing lanolin
1.5 Jojoba oil 6 Cetyl isooctanoate 4 POE-2-octyldodecanol (114020 mol) 2.0 Ethylparaben 0.2 Butylparaben 0.1 Fragrance
0.3" (B) Soluble collagen (protease treatment) 1 Soluble succinated collagen (protease treatment) 1 Dipropylene glycol 2 Carboxymethyl polymer 0.2 L-arginine 0.2 Purified water
Residue (manufacturing method) According to Example 1.

Comparative Example 3 Lotion (A) Purified water Amount to make the total 100% Glycerin 2 Soluble succinated collagen (protease treatment) 0.2 1.3-Butylene glycol 10 (B) Ethanol 7 POE-hydrogenated castor oil (
E060 mol) 1 fragrance
0.05 Methylparaben O, ■
(Manufacturing method) According to Example 6.

(Margin below) Table 2 Procedural amendment (voluntary) 1.Display of the incident 1985 Patent Application No. 93076 2. Name of the invention cosmetics 3. Person who makes corrections Relationship to the case Patent applicant 4. Subject of correction Detailed description of the invention in the specification 5. Contents of correction (1) Delete the 4th line on page 12 of the statement.

that's all

Claims (1)

[Claims] (1) A cosmetic containing one or more types of soluble collagen and its derivatives and one or more types of lecithin.