JPS61239881A - Cultivation apparatus - Google Patents

Cultivation apparatus

Info

Publication number
JPS61239881A
JPS61239881A JP7830285A JP7830285A JPS61239881A JP S61239881 A JPS61239881 A JP S61239881A JP 7830285 A JP7830285 A JP 7830285A JP 7830285 A JP7830285 A JP 7830285A JP S61239881 A JPS61239881 A JP S61239881A
Authority
JP
Japan
Prior art keywords
exhaust gas
line
air
compressor
culture tank
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7830285A
Other languages
Japanese (ja)
Inventor
Kiyoshi Sasaki
佐々木　亀代司
Masakatsu Fujimoto
藤本　正勝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi Ltd
Original Assignee
Hitachi Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi Ltd filed Critical Hitachi Ltd
Priority to JP7830285A priority Critical patent/JPS61239881A/en
Publication of JPS61239881A publication Critical patent/JPS61239881A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/20—Degassing; Venting; Bubble traps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas

Landscapes

  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

PURPOSE:To enable the remarkable reduction in the operation power of a culture apparatus, by removing CO2 from the exhaust gas generated from a fermentation tank and reusing the remaining gas free of CO2 as a gas for introducing into the fermentation tank. CONSTITUTION:The exhaust gas generated in the fermentation tank 2 is passed through the aseptic filter 6, the line 9 and the exhaust gas control valve 3, and a part of the gas is discharged to the outer atmosphere while the major part is introduced through the line 11 to the recycling compressor 4. The compressed gas is sent to the CO2-removing apparatus 5 via the line 12 and the treated gas free of CO2 is passed through the line 13 to the line 8. The line is fed with compressed aseptic air produced by compressing air with the compressor 1 and sterilizing with the aseptic filter 6. The joined stream is introduced into the fermentation tank 2.

Description

【発明の詳細な説明】 〔発明の利用分野〕 木分明は、微生物や細胞等を培養槽内で培養する培養装
置に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Application of the Invention] Kibunmei relates to a culture device for culturing microorganisms, cells, etc. in a culture tank.

〔発明の背景〕[Background of the invention]

培養槽内で微生物や細胞等を培養する培養装置は、持関
昭５８−３８７３８４号公報、特開昭５８−９８０８５
号公報、特開昭５８−７８５８４号公報、特開昭５７−
］８６４８７号公報等に開示さｒ、でいる。A culture device for culturing microorganisms, cells, etc. in a culture tank is disclosed in Mochiseki No. 58-387384 and Japanese Patent Application Laid-Open No. 58-98085.
No. 1, JP-A-58-78584, JP-A-57-
] Disclosed in Publication No. 86487, etc.

一般に、培養槽内での培養をこ際しては、培養液中をこ
酸素を溶存させるために、空気が培養槽内に供給される
。この供給のため？こは、空気を１〜３　　　　　　・
′ａｔｇ　　ｋこ圧縮する圧縮機が設けろｒる。培養槽
へ供給さｊる空気は、培養液への酸素溶存を十分ｔこ行
なわせるため、培養のための絶対消費址トこ比し大幅に
超過するよう１こ大量に供給さｒている。そして、培養
槽からの排気ガスは、そのまま大気中に放出さｎている
。Generally, when culturing in a culture tank, air is supplied into the culture tank in order to dissolve oxygen in the culture solution. For this supply? This is air 1-3 ・
A compressor is provided to compress the air. The air supplied to the culture tank is supplied in a large amount so as to greatly exceed the absolute consumption power for culture in order to sufficiently dissolve oxygen into the culture solution. The exhaust gas from the culture tank is released into the atmosphere as it is.

ところで、最近の傾向として、一度ｔこ大量の培養を行
なう目的で培養装置の大型化が考えらｒている。この大
型化ｔごともない、空気を培養槽ｔこ供給するため１こ
設けらｒる圧縮機も大型のものが必要とさｒる。我々の
計算では、５０　ｍ”の培養槽ｔこ対して要求さｊる圧
縮機の容量は１００ＫＷ程度となる。したがって、こｒ
はかなり大きなものと言える。圧縮機を大型化すること
は、運転動力費のア゛ノブｐこつながるので、出来るだ
け小型のものが望まｎる。Incidentally, as a recent trend, it is being considered to increase the size of culture apparatuses for the purpose of cultivating a large amount of cells at once. In addition to this increase in size, a large compressor is also required to supply air to the culture tank. According to our calculations, the capacity of the compressor required for a 50 m" culture tank is approximately 100 KW. Therefore, this
can be said to be quite large. Increasing the size of the compressor will lead to an increase in operating power costs, so it is desirable to make it as small as possible.

〔発明の目的〕[Purpose of the invention]

本発明の目的は、運動能力費を低域可能な培養装置を提
供することである。An object of the present invention is to provide a culture device that can reduce exercise performance costs.

〔発明の概要〕[Summary of the invention]

本発明は、培養槽から排気さｎる排気ガス中には二酸化
炭素（ＣＯ雪）を含んではいるがまだ充分な酸素が含有
さｎ、ていることを利用し、排ガスを昇圧する循環圧縮
機と、昇圧さｎ、た排ガス中の二酸化炭素を除去する二
酸化炭素除去器とを設け。The present invention utilizes the fact that the exhaust gas exhausted from the culture tank contains carbon dioxide (CO snow) but still contains sufficient oxygen, and uses a circulating compressor to boost the pressure of the exhaust gas. and a carbon dioxide remover to remove carbon dioxide from the pressurized exhaust gas.

二酸化炭素の除去さｒた排ガスを培養槽に供給している
空気＃ｃ萱流させたことを特徴とする。この場會、循環
圧縮機は、排ガス自体がまだかなりの圧力を有している
のでわずかに昇圧可能なもので良く、小容量のもので良
い。また、空気を昇圧するための空気圧縮機自体も、循
環再利用さｎ、る分だけ少ない流量を吐出するもので良
いので、小型化は可能である。It is characterized in that the exhaust gas from which carbon dioxide has been removed is passed through the air supplying the culture tank. In this case, since the exhaust gas itself still has a considerable pressure, the circulation compressor may be one that can slightly increase the pressure and may have a small capacity. In addition, the air compressor itself for pressurizing the air can be made smaller because it can discharge a smaller flow rate to compensate for the circulation and reuse.

！　　　　　　〔発明の実施例〕 以下、未発明を図面に示す本発明の一実施例により詳細
に説明する。! [Embodiments of the Invention] Hereinafter, an embodiment of the present invention will be described in detail with reference to the drawings.

第１図は本発明の一実施例にかかる図面である。FIG. 1 is a drawing according to an embodiment of the present invention.

この図において、空気圧縮機１は、培養槽２Ｃ空気を供
給するために空気を昇圧するためのものである。その容
量は培養槽２で消費される絶対酸素緻をまかなうに必要
な空気量をベースどして、決定さｎ、る。培養槽２は、
被培養物を培ＩＩ液中で培養するためのものである。培
養に際しては、空気の供給を受ける。排気ガス調節弁３
は、培養槽２から排出さｎ、る排ガスの排装置を調節す
る。循環圧縮機４は、培養槽２から排出される排ガスの
大部分を取込み、こ１．を昇圧して吐出する。この場菅
、循環圧縮機４は、培養槽２の入口部ａの圧力と出口ｗ
６ｂの圧力差は小さいので、揚程の小さなもので良い。In this figure, an air compressor 1 is used to pressurize air in order to supply air to a culture tank 2C. Its capacity is determined based on the amount of air required to cover the absolute oxygen consumption in the culture tank 2. Culture tank 2 is
This is for culturing a cultured product in medium II. During cultivation, air is supplied. Exhaust gas control valve 3
adjusts the exhaust device for exhaust gas discharged from the culture tank 2. The circulation compressor 4 takes in most of the exhaust gas discharged from the culture tank 2, and 1. The pressure is increased and discharged. In this case, the circulation compressor 4 controls the pressure at the inlet a of the culture tank 2 and the pressure at the outlet w.
Since the pressure difference between 6b and 6b is small, it is sufficient to use one with a small lift.

ＣＯａ除去器５は、排ガス中に含まｒ、るＣ０２を除去
するためのものであり、例えば含酸ゼオライトを用いた
吸着器やＮａＯＨ溶液によるＮ　ａＯＨ洗浄塔などが使
用可能である。７〜】３は導管である。６は除菌フィル
ターである。The COa remover 5 is for removing CO2 contained in the exhaust gas, and for example, an adsorption device using acid-containing zeolite or an NaOH washing tower using NaOH solution can be used. 7~] 3 is a conduit. 6 is a sterilization filter.

導管７から供給さｊる空気（大気圧）は、空気圧縮機１
により１例えば２ａｔｇに昇圧される。The air (atmospheric pressure) supplied from the conduit 7 is supplied to the air compressor 1.
The voltage is increased to 1, for example, 2 atg.

昇圧後の空気は、除菌フィルター６、導管８を経て培養
槽２ｃ供給さｎる。培養槽２からは、排ガスの一部が導
管９．弁３．導管】０を介して大気中に放出さｎる。排
ガスの大部分は、導管９．１１を介して、循環圧縮Ｊ１
４Ｃ供給され、ここで循環再使用可能な圧力に昇圧さｎ
、る。昇圧後の排ガスは、導管】２を介してＣＯ２除去
器５に供給さｎ、ここで排ガス中のＣＯ２が除去され、
る。ＣＯ２除去後の排カスは、循環内使用のため、導管
１３を介して導管８内を流ｊる圧縮空気と傍流される。The air after pressurization is supplied to the culture tank 2c via a sterilization filter 6 and a conduit 8. A part of the exhaust gas from the culture tank 2 is transferred to the conduit 9. Valve 3. discharged into the atmosphere via a conduit. The majority of the exhaust gas is transferred via conduit 9.11 to the circulating compressor J1
4C is supplied, where it is circulated and boosted to a reusable pressure n
,ru. The exhaust gas after pressurization is supplied to a CO2 remover 5 via a conduit 2, where CO2 in the exhaust gas is removed.
Ru. The waste residue after CO2 removal is passed through the conduit 13 alongside the compressed air flowing in the conduit 8 for use in the circulation.

つまり、培養槽２には、空気圧縮機】Ｃよって圧縮さｒ
た圧縮空気と、循環圧縮ｆｆ１４で昇圧さｒＬＣ０２除
去器でＣＯ２の除去さｊ、た排ガスとが供給さｊ、るこ
とになる。In other words, the culture tank 2 is compressed by the air compressor ]C.
The compressed air that has been compressed and the exhaust gas that has been pressurized by the circulation compressor ff14 and from which CO2 has been removed by the LC02 remover are supplied.

本実施例によｊば、揚程の高い空気圧縮機の容量は培養
に要する絶対酸素量なベースに決定できるので空気圧縮
機の消費動力は従来技術に比し大巾に小さくて済む。According to this embodiment, the capacity of the air compressor with a high lift can be determined based on the absolute amount of oxygen required for culture, so the power consumption of the air compressor can be significantly reduced compared to the conventional technology.

また培養液ｔこ対する酸素溶存ｔこ必要な空気流速即ち
培養槽内の空気流速は揚程の小さな循環圧縮ｆｉ５で補
う方式なのでこの分の消費動力は小さい。In addition, since the required air flow rate for the culture solution t and dissolved oxygen t, that is, the air flow rate in the culture tank, is compensated for by the circulating compression fi5 with a small head, the power consumption for this is small.

廻に−Ｃ０２除去器９の消費動力も非常に小さいので本
発明によｎ、ば従来方式に比べ消費動力を大幅に低域し
たランニングコストの非常に経済的す培養装置を得るこ
とができる。Since the power consumption of the -C02 remover 9 is also very small, the present invention makes it possible to obtain a very economical culture device with running costs that are significantly lower in power consumption than conventional systems.

〔発明の効果〕〔Effect of the invention〕

以上説明したように本発明によｎ、ば、運転動力費を大
幅に低減することができる。As explained above, according to the present invention, operating power costs can be significantly reduced.

【図面の簡単な説明】[Brief explanation of the drawing]

′！ＩＬ１図は本発明の一実施例を示す図である。 ′! Figure IL1 is a diagram showing an embodiment of the present invention.

Claims (1)

【特許請求の範囲】[Claims] １、培養槽と、該培養槽へ空気を圧送する空気圧縮機と
を備えた培養装置において、該培養槽から排気される排
ガスを昇圧する循環圧縮機と、該昇圧された排ガス中の
二酸化炭素を除去する二酸化炭素除去器とを設け、該二
酸化炭素除去器を経た排ガスを前記酸素または空気と合
流させたことを特徴とする培養装置。1. In a culture apparatus equipped with a culture tank and an air compressor that pumps air to the culture tank, a circulation compressor that boosts the pressure of exhaust gas exhausted from the culture tank, and carbon dioxide in the pressurized exhaust gas. 1. A culture apparatus comprising: a carbon dioxide remover for removing carbon dioxide; and exhaust gas passing through the carbon dioxide remover is combined with the oxygen or air.
JP7830285A 1985-04-15 1985-04-15 Cultivation apparatus Pending JPS61239881A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7830285A JPS61239881A (en) 1985-04-15 1985-04-15 Cultivation apparatus

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7830285A JPS61239881A (en) 1985-04-15 1985-04-15 Cultivation apparatus

Publications (1)

Publication Number Publication Date
JPS61239881A true JPS61239881A (en) 1986-10-25

Family

ID=13658125

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7830285A Pending JPS61239881A (en) 1985-04-15 1985-04-15 Cultivation apparatus

Country Status (1)

Country Link
JP (1) JPS61239881A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102373243A (en) * 2011-11-08 2012-03-14 中粮生物化学（安徽）股份有限公司 Method for preparing citric acid through fermentation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102373243A (en) * 2011-11-08 2012-03-14 中粮生物化学（安徽）股份有限公司 Method for preparing citric acid through fermentation

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