JPS61193672A - Method and apparatus for dispersing by reversal pulse electromagnetic field - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed Description of the Invention] [Field of Industrial Application] From the perspective of colloid chemistry or crystallography, regardless of whether it is biological or inorganic, in nature, molecules or particles dispersed in a certain solvent are subject to changes in temperature, pressure, concentration, and pH. Depending on the conditions such as polarization, substrate, membrane, etc., the shapes may be parallel to each other, planar, spherical, cylindrical, etc.
It is known that an azimuth arrangement such as a three-dimensional lattice pattern can be taken.

This azimuth alignment means RNA transcription, virus proliferation, protein synthesis, clouding of the lens of the eye (cataract), atheroma precipitation in blood vessels, liquid crystal display, precipitation of slurry containing fine abrasive grains, tofu production, ion fruster in vacuum. It is believed to be closely related to many events related to the occurrence of

Furthermore, these orientational arrangements can be considered to occur in a loosely bound gel system due to the gelation process of the sol or the anisotropy of the shape of colloidal particles. Developing this idea, if it is possible to prevent substance molecules or particles from oriented and forming a gel system, it will be possible to suppress the abnormal proliferation of cancer cells, treat cataracts, and precipitate intravascular atheroma. It can be used in a wide range of industrial fields in medical and biological engineering, such as removal of tofu, deflocculation of tofu, and prevention of settling of abrasive slurries.

[Conventional technology]

Conventionally, the following three methods are known for producing a sol, that is, for dispersing material particles in a solvent.

A. Electrical dispersion method: A spark discharge is caused in a liquid using a platinum electrode or the like to obtain a sol in which platinum is dispersed.

B. Mechanical dispersion method: A sol is obtained by grinding sulfur and urea together and adding water.

C. Peptization (peptization) method: Hydrochloric acid or iron chloride is added to iron hydroxide to obtain a sol.

Until now, no dispersion method using an inverted pulsed electromagnetic field is known.

[Problem that the invention seeks to solve]

When trying to apply the above-mentioned conventional technology to living organisms, A is a somewhat rough method and comes with side effects such as tissue burnout and destruction, B also has no means of actually grinding the substance, and C
Although it can be carried out by means such as injection or dripping of an appropriate electrolyte, concerns about side effects remain. In addition, both the ABC method and the depth that can be reached are limited, and the dispersion force can reach only 1 to 2 cm at most. In recent years, hyperthermia therapy has been developed as a treatment for malignant tumors and is becoming more and more effective. This method applies a high frequency of 8 MHz to the object and uses the vibrations of water molecules and frictional heat to heat the object to 42 to 43 degrees Celsius. The temperature was raised to . Although there is an advantage in being able to reach a depth of 12.5 cm, it is questionable to what longitude macromolecules can be vibrated and further dispersed by high frequency.

In addition, since the main focus is on temperature elevation, there is a drawback that it cannot be applied to the brain, eyeballs, etc.

Therefore, the present invention aims to provide a dispersion method and an apparatus for reducing the side effects on living organisms and increasing the reach depth of the dispersion force to 20 to 30 cm.

[Means for solving problems]

From single atoms such as hydrogen and oxygen to macromolecules such as proteins, when all or part of them has an electric charge, it is assumed that they are ionized in a broad sense. In addition, molecules and ion groups, including the electric double layer that occurs at the interface between electrolyte and non-electrolyte or on the surface and inside of the membrane, are arranged in linear, planar, spherical, cylindrical, three-dimensional lattice, etc. The aggregated portion will be collectively referred to as the substrate body. Defined in this way, first, ionized particles aggregate to form a substrate, then bonds occur between object atoms aligned on the surface, and these newly synthesized ion particles are separated from the original substrate. It is possible to see natural phenomena in an integrated manner, such as when a new substrate is created by peeling it off. In addition, cases where agglomeration continues monotonically or cases where substrate bodies grow together are also considered, and similar phenomena have also been found. The object of the present invention is to prevent ionized particles from aggregating to form a substrate body or from synthesizing or multiplying therein, with fewer side effects and deeper reach.

To achieve this purpose, a DC pulse of 0.1 to 1000 Hz and a pulse width of 3 msec or less is generated, and
For example, an air-core coil with a diameter of about 250 mm was connected to a pulse power source whose polarity changes with a reversal period of 300 seconds, and the generated reversal pulse electromagnetic field was applied to the object. In this case, the object may be a gas, a liquid, a solid, or a mixture thereof, and may be an inorganic object or a living organism.

[Effect]

When an inverted pulsed electromagnetic field is applied to an object, a dispersion effect of material particles occurs. When considering its effect, first,
A Foucault current accompanied by a unidirectional eddy flow of charged particles flows within the object due to a pulsed electromagnetic field without reversal. In this case, the flow directions of negatively charged particles such as electrons and negative ions and positively charged particles are opposite. In addition, since a pulsed electromagnetic field is used, the change in magnetic flux density per unit time can be increased, and an impulsive force acts on the particles constituting the object with each pulse. When the strength of the electromagnetic field is small, light charged particles such as electrons cause an impulsive vortex rotation movement in one direction in response to the pulse in the solvent, reducing the charge between the nearby electrical double layers. It acts as a neutralizer. Even with this working length, the above-mentioned dispersion due to self-diffusion of the oriented aggregates tends to occur, but as the strength of the electromagnetic field is further increased, hydrogen, oxygen, carbon, nitrogen, Na, F, K A vortex flow of ions occurs, and then a vortex flow of giant ions such as protein molecules occurs. If this continues, the entire aggregate will rotate, but in this invention, the polarity of the pulse group is periodically reversed, so a force that reverses the rotation, that is, a rotational vibration force, acts, and the charges of the constituent particles are It is thought that different forces and moving speeds are generated in each particle due to differences in mass, viscosity, etc., and this acts as a dispersion force that separates the particles from each other. In addition, it is expected to have an effect of suppressing the progress rate of the reaction based on interfering with the alignment->proliferation->dissociation conditions of molecules considered to be necessary for the synthesis of cancer proteins.

〔Example〕

Example 1 Commercially available tofu was made into 0.05 mm long, 0.02 mm wide, and 0.0 mm thick.
A 1 mm section was made, immersed in a drop of water on a mounting glass, and while observed under a microscope, a 6 Hz pulsed DC electromagnetic field that reversed at a cycle of 1.2 seconds was generated from a coil with an iron core. The lever was applied to the section. The strength of the electromagnetic field at this time was 630 Gauss as a magnetic flux density when the maximum value of the pulse was measured with a Gaussmeter placed at the sample position.

In this experiment, when the pulsed electromagnetic field started to be reversed, decomposition started around the section, and the tofu became transparent and was observed to rapidly disperse into the water.

That is, it became transparent in 15 seconds and dispersion disappeared in 23 seconds. On the other hand, when no reversed pulsed electromagnetic field was applied, no change occurred in the section even after 30 minutes.

Application example 1 A 54-year-old woman, who was found to have a partial cataract in the upper part of her left eye, was examined by an ophthalmologist. A 15Hz DC pulsed electromagnetic field that reversed every 2 seconds was generated from a coil with an iron core at a strength of 420 Gauss in the affected area. After applying it for 30 minutes to the top of the eyelid, and then applying it for an additional 30 minutes after a 2-hour break, the cloudiness in the eyeball that was initially seen disappeared immediately, and compared to the right eye, which was normal from the beginning. It has also recovered to such an extent that there is no noticeable difference.

Application example 2 An 8 Hz DC pulse electromagnetic field with a diameter of 200 mm is applied to the scalp of a 53-year-old man who is suffering from increasing gray hair.
It was generated from a 40-turn air-core coil, and the scalp magnetic flux density was set to 200 Gauss, and the coil was shifted little by little for 30 minutes every day. After 2 weeks of this, the tips were white in the gray hair, and the area near the hair roots was Hair with a length of 5 mm turned black can be seen here and there, and the trend of increasing gray hair has stopped.

Application example 3 When a 48-year-old female suffering from athlete's foot was treated with an 800Hz DC pulsed electromagnetic field that reversed every 250 seconds and was applied to the affected area for 20 minutes using a coil with an iron core at a magnetic flux density of 600 Gauss, the itching sensation decreased. The moisture in the affected area was removed, so I continued doing this three times a day for a week, and as a result I was completely cured.

Comparative Example 1 A 57-year-old female who was experiencing pain in her left thigh was treated with a non-reversing 20Hz DC electromagnetic pulse generated from an air-core coil with a diameter of 200mm and applied to the affected area for 25 minutes at a magnetic flux density of 180 Gauss. The pain in that area subsided after two hours, but the next day, she started feeling pain in her right thigh. Therefore, we applied a 20Hz DC pulse electromagnetic field with a strength of 180 Gauss for 25 minutes, reversing every 10 seconds.
The pain in that area went away after an hour and a half, and the patient had completely recovered without any new pain in other areas the next day. This is considered to be due to an increased dispersion effect during detachment of intravascular atheroma precipitates. In other words, it is thought that the unidirectional vortex flow caused large clumps to detach and embolize into small blood vessels elsewhere, but now the rotational vibrations have caused them to be finely dispersed, and as a result embolus transfer has disappeared.

Comparative Example 2 When a 200 mm coil was placed on the head of a 14-year-old female complaining of head heaviness and a DC pulsed electromagnetic field with no reversal was applied at a coil input voltage of 150 V, the head became stiff in 10 minutes. I also felt a dull pain in the area where the coil hit. Therefore,
2 at a voltage of 280V while performing reversal with a period of 3.5 seconds.
After 0 minutes of application, the feeling of fatigue and local dull pain disappeared, and after 30 minutes, the head felt refreshed and weight was lifted.

As can be seen from this example, unless the polarity is reversed, a strong electromagnetic field cannot be applied to the affected area for a long time due to side effects, and its effectiveness is diminished.

In addition to these examples, there were many cases where pain and stiffness were transferred to other areas when a pulsed electromagnetic field without reversal was applied, but in all cases, such transfer phenomena disappeared when a reversed pulsed electromagnetic field was applied. Are known.

Application example 4 A 55-year-old man who has trouble raising his left arm above his shoulder every morning when he wakes up, uses 10H to invert every 15 seconds before going to bed.
A DC pulsed electromagnetic field of z was generated from an air-core coil with a diameter of 250 mm and 65 turns, and the coil was inserted into the base of the left arm, and the magnetic flux density at the affected area was set to 730 Gauss. When the field was applied for 15 minutes, the next morning, the left arm was about 10 cm higher than the shoulder. Now I can give. After increasing the application time to 30 minutes and continuing this therapy for three more days, the patient was able to raise his left arm completely, and even after one week, he was completely cured, with no recurrence.

Application example 5 On December 13, 1980, a 50-year-old man presented with symptoms of a transient cerebral infarction, including mild aphasia accompanied by a lack of reading comprehension for approximately 4 hours, and an inability to recognize the central visual field of the right eye. upper left migraine,
He developed complications that made him feel sick all over his body. A few days later, an X-ray CT scan at the hospital revealed no abnormalities. and,
Because of the fear of recurrence, he continued to take antithrombotic drugs and cardiotonic drugs, and continued to visit the hospital. Also, at the recommendation of a sports doctor, he started jogging 5 km every morning from March 1980, and worked to prevent recurrence of cerebral infarction by improving peripheral blood circulation. The index measured by the accelerometer plethysmometer invented by Dr. Koyamauchi (Determination of blood circulation by accelerometer and its application: 36th Japanese Society of Physical Fitness Medicine, presentation number 512) was -25 before the start of sports. +38 after half a year
The results were in the 30s, indicating that the effects of exercise were significant. However, blood test data shows that in September 1981, γ-
GTP66 and HDL-cho75, and there was no risk of liver damage, arteriosclerosis, myocardial infarction, etc.

In July 1980, before going to bed, an 8Hz DC pulsed electromagnetic field that reversed every 30 seconds was generated from an air-core coil with a diameter of 200mm and 40 turns, and this was placed over the head for 15 minutes to stimulate the heart, The pressure was applied to the affected area from the back side of the lungs for 20 minutes at a strength of 70 to 150 Gauss. The acceleroplethysmography index before and after this test was +38 and +48, respectively, indicating a significant improvement in peripheral blood circulation. This procedure was continued once every three days for one month, and a blood test in August 1981 revealed that γ-GTP was 48 and HDL-cho was 68, which was a significant improvement from the previous year's data. Taken together, these results show that inverted pulsed electromagnetic fields are effective in dispersing and removing intravascular atheroma, improving peripheral blood circulation through cell activation, and are also effective for people who are trying to maintain a healthy body by making a habit of playing sports. It turns out that it has the effect of further improving it.

Application example 6 In March 1980, a 55-year-old man started visiting an otolaryngologist due to hearing loss in his right ear.He was diagnosed with cervical lymph gland enlargement at a certain university hospital, and further detailed examination revealed a nasopharyngeal tumor. (
was declared malignant).

Radiation therapy began at a cancer center in June of the same year, and after a total of 70 outpatient treatments, the tumor was almost gone, but swelling still existed on both cheeks and under the jaw, and he still had difficulty speaking. Starting in January 1958, an 8Hz DC pulsed electromagnetic field that reverses every 10 seconds was generated from an air-core coil with a diameter of 200mm, and the magnetic flux density at the affected area was 150 Gauss for 5 hours every night while sleeping.This continued for a week, resulting in swelling. started to recede. After gaining strength from this and using this dispersion treatment for about half a year, my doctor diagnosed that my condition was progressing very well, and I have not had a recurrence since then.

As can be seen from this case, the effectiveness of cancer treatment can be enhanced by combining conventional radiation with the dispersion method using the inverted pulsed electromagnetic field of the present invention.

At present, it is not clear what kind of mechanism the therapeutic principle is based on, but it is possible that some kind of action or effect (currently present) that interferes with the assembly and alignment of oncogenes and the synthesis of oncoproteins, which are necessary for the proliferation of cancer cells, is still unclear. It is assumed that this is based on the dispersion force caused by the rotational vibration of molecular particles). Further research must be conducted in the future regarding the effects of applying only this inverted pulsed electromagnetic field and animal experiments using mice bearing malignant tumors.

The method of this invention is different from the conventional method of shrinking a malignant tumor by irradiating the affected area with high frequency waves of about 8 MHz and raising the temperature of that area to 42 to 43°C, in that it hardly involves any increase in temperature of the affected area. Because there is no hair, it is now possible to apply it to the brain, eyeballs, etc., which was impossible until now, and the side effects are extremely minor and the size is 20 to 30 cm.
At this stage, we are accumulating clinical cases involving brain tumor patients, but the outlook is bright.

This concludes the description of the examples, comparative examples, and application examples, but even if the coil is replaced with an electrode in the same manner as in a low-frequency treatment device, a considerable effect can be achieved.

[Reason for numerical limitation]

Pulse width...if it is too wide, the magnetic flux density change rate dφ/dt
is small and a high voltage cannot be induced in the object, so the dispersion effect is reduced.

It has been experimentally found that 3 msec or less is good.

If the frequency of the DC pulse is too high, the overall wave height will decrease due to circuit limitations and the dispersion effect will weaken. If it is too low, the impulsive vortex flow of molecular particles becomes slow and the dispersion effect is weakened.

If we consider the case where the inversion period is extremely short and inversion is performed every pulse, this is an alternating current pulse, and the angular range of rotational vibration of the molecular particles becomes narrower, resulting in a weaker dispersion effect. If it is extremely long, it is the same as abolishing inversion, and various side effects will occur because the substance cannot be finely dispersed.

〔Effect of the invention〕

As explained above, this invention disperses a substance by causing rotational vibration in molecular particles by applying a group of DC pulses whose polarity is periodically reversed to an object through an electromagnetic induction means such as a coil or an electrode. Therefore, if applied to the human body, it will be possible to treat and prevent diseases such as lower back pain, stiff shoulders, cataracts, cerebral infarction, myocardial infarction, and malignant tumors with very few side effects and deep reach, and if applied to industry, it will be possible to treat and prevent diseases such as lower back pain, stiff shoulders, cataracts, cerebral infarction, myocardial infarction, and malignant tumors. This has the effect of facilitating the dispersion of

Claims (1)

[Scope of Claims] 1. 0.0 for substances and biological substances that tend to have linear, planar, spherical, cylindrical, three-dimensional lattice, etc. orientation arrangements in a solvent.
Dispersion method 2 characterized by applying an electromagnetic field generated from a coil or electrode connected to a pulse power source whose periodic polarity is reversed for 0.1 to 300 seconds. Direct current pulses with a frequency of 0.1 to 1000 Hz and a pulse width of 3 msec or less. Occurs and 0.01 seconds to 300
An electromagnetic dispersion device in which a coil or electrode is connected to a pulse power source whose polarity changes with a reversal period of seconds.