JPS61185167A - Laxative food - Google Patents

Abstract

PURPOSE:To laxative food, containing alginic acid, a flavonol (glycoside) such as kaempferol or (iso)quercetin and edible alkali (earth) metal ion or salt as essential components, and capable of improving chronic constipation symptoms. CONSTITUTION:A laxative food containing (A) alginic acid contained in brown algae, in large amounts (B) a flavonol (glycoside) such as kaempferol, quercetin and isoquercetin contained in grapes or figs and (C) an edible alkali (earth) metal ion and/or salt such as common salt, potassium chloride or calcium chloride as essential constituent components. Preferably, the above-mentioned components (A), (B) and (C) are fragments, powder or aqueous extract of a natural plant body containing the components.

Description

DETAILED DESCRIPTION OF THE INVENTION (Subject of the Invention) The present invention provides health foods, especially those that are consumed on a regular basis.
Regarding laxative foods that can be expected to have comfortable bowel movements.

(Aotatami) Regular bowel movements are an important phenomenon for a person's healthy life, but in reality, people who do not have regular bowel movements, that is, people with habitual constipation, are more likely to be female or obese people. Very widely seen. This symptom itself does not necessarily mean that it is a particularly serious illness, but rather it may be caused by six causes of discomfort, depression, lethargy, or fatigue, which is a nostalgic memory of comfortable bowel movements. In some cases, neurological symptoms such as headaches, hot flashes, dizziness, stiff shoulders, and lower back pain, bad breath, loss of appetite, and abdominal *N! It may also cause gastrointestinal symptoms such as 4 sensations, pressure or pain in the epigastric region, nausea, and flatulence.

Symptomatic treatments for constipation mentioned above include taking laxatives and enemas, but in many cases these measures not only have an unfavorable effect on the intestinal mucosa, but also the habit of relying on these drugs is The problem is that it weakens the defecation reflex. Therefore, ``the key to relieving constipation is improving your eating habits.''

For this reason, many books have taught for a long time that ``eat lots of vegetables and fruits that have the property of promoting intestinal motility,'' but as a practical matter, it is difficult to eat because of economics and taste. Not only is it not possible to eat a lot of vegetables and fruits (many people with chronic constipation do not like vegetables and fruits), but also the increase in powdered foods and meat foods due to the Westernization of dietary habits. , the intake of fiber from conventional cooked rice has been reduced, resulting in an even greater increase in constipation.

(Objective of the Invention) The present invention provides a laxative food that does not require special intake of vegetables, fruits, or other fibrous foods, and is effective in improving chronic constipation symptoms when used as a daily meal. The purpose is to

(Structure of the Invention) The gist of the present invention is to provide flavonols selected from the group consisting of alginic acid, kaempferol, quercetin, and inquercetin or their glycosides, and edible alkali metals and/or alkaline earth metals. Regarding laxative foods containing alkali metals and/or salts as essential components, the present inventor has conducted various studies and experiments on ways to improve chronic constipation through a natural diet. Among indigestible substances that have the property of swelling in the body, in particular alginic acid and flavonols or their glycosides selected from the group consisting of kaempferol, quercetin, and inquercetin;
It has been found that the combination of edible alkali metals and/or alkaline earth metals with alkali metals and/or salts is extremely effective for this purpose.The present invention is based on this finding.

Here, alginic acid is poly(D-mannouron), which is contained in large amounts (15 to 80% of the dry matter) in brown algae such as Macomb, Tosiliconbu, Tororokonbu, Arame, Norokashima, Wakame, Hijiki, Akamoku, Yoremoku, Nejimoku, and Isomoku. This is a compound (β-1,4 bond) that exists in the cell walls of most brown algae mainly in the form of calcium salts, magnesium salts, or free acids, but some sodium or potassium salts are present in the cell walls of most brown algae. It also exists in form. When this substance and its salts are ingested into the gastrointestinal tract, it absorbs water in the small intestine and large intestine, turns into a gel, and swells to 20 to 30 times its original volume, as shown in Table 1 below.

(Left below) Table-1 Stomach Small intestine Large intestine (PH1-2) (PH7,5-8) (P)17
．． 5-8)^G-Ha release, solidification and precipitation Water absorption gelling Water absorption gelling AC-K Same as above Same as above
Same as above AC-Zhong M8 Same as above Same as above Same as above AC-Repair Ca Same as above Same as above Same as above A
C-Same as above Same as above Same as above Note) AG Nialginic acid residue Of course, in actual situations, each carboxyl group of each D-mannouronic acid unit, which is about 60 to 80 depending on the type and amount of cations present, , or a mixed salt in which respective metal cations are randomly bonded to the carboxyl groups of adjacent D-mannouronic acid units is formed.

Next, kaempferol and its glycosides are found in many species of the genus Prunus (Cenus, Prunug, Rosacea).
e) Plants.

For example, P, domestica
,P.

1nsitia, P.
ceracifena, P
, 5alicina (plum) P, sis+oni
(Simon plum), P, americana
(American eggplant%//%), P, hortulan
a (Hautulanas peach), P, nigrs (Nigeras peach), P, 5unso-niana (
P, angustifol
ia-marsch (Agustifolius peach), and its main glycosides are, for example, 3-rutinoside, 3-glucoside, 3-galactoside, and 3.7-
These include bis-rhamnoside, 3-7 rabinosyl-7-rhamnoside, etc. In addition, quercetin, isoquercetin, and their glycosides are contained in fruits such as grapes and figs in addition to the fruits of plants of the genus Prunus, and the main glycosides thereof are their 3-rhamnosides.

Furthermore, the edible alkali metal and/or alkaline earth metal salts that are the third component of the present invention include, for example, common salt, potassium chloride, calcium chloride, magnesium chloride, sodium sulfate, potassium sulfate, calcium sulfate, magnesium sulfate, Sodium phosphate, sodium hydrogen phosphate,
Potassium phosphate, potassium hydrogen phosphate, calcium phosphate, magnesium phosphate, sodium birophosphate, potassium birophosphate, sodium metaphosphate, potassium metaphosphate, polymerized sodium phosphate, sodium bicarbonate,
Examples include calcium carbonate and magnesium carbonate.

Additionally, the inventor has discovered that pectins are effective as auxiliary ingredients because they help lubricate between the fecal mass and the +m wall. Therefore, it is preferable to add an appropriate amount of pectin to the food of the present invention in addition to the above three components.

Each of the above components can be constituted by blending individual components as desired. However, in reality, it is rational to use plant fragments, powders, or aqueous extracts containing each component, and the fibers and flavor of these plants are not only useful as food, but also as laxatives. Increase the value of food. Table 2 below shows Ha, K and Ca of representative edible brown algae.
Table 3 shows the contents of Ha, Ca, and Ca in typical fruits containing kaempferol, quercetin, and isoquercetin.
and Mg content, and Table 4 shows the pectin content in one representative flavonol-containing fruit.

Table 2 ゛ Note) Numbers are percentages by weight of dry matter (blank below) Table 3 Note) Numbers are grams per 100g Table 4 The food according to the present invention may be powder, paste, or any molded product as desired. It is eaten in the form of a liquid, either as a food as it is, or cooked and eaten as a food ingredient with other ingredients. Therefore, as necessary, starches, meats, oils and fats, vegetables, fruits, milk, eggs, honey, acidulants, seasonings, spices, and herbal extracts.

Thickeners, binders, surfactants, pigments and coloring agents, fragrances,
Other food ingredients and food additives such as stabilizers, encapsulating agents, chelating agents, etc. are freely used. However, canned or bottled beverages,
The purpose is to prepare confectionery such as bread spreads, biscuits, cutlets, rice crackers, and gum, snack foods, frozen pizza, cake mixes, dessert foods such as pudding, jelly, and Bavarois that can be consumed as is. As is well known, alginic acid has gel-forming ability and forms gels alone or in the coexistence with other gel-forming substances such as pectin, guar gum, and low-strength soot bean gum. It is advantageous to make the invented food into a gel food together with a palatable material because it makes the invented food easier to eat.

(Function) When the food of the present invention is ingested, kaempferol, quercetin, isoquercetin and their glycosides taken into the digestive tract as one food reach the large intestine without being digested. In addition, alginic acid and its salts taken in at the same time encounter alkali in the intestines and become insoluble salts, which gradually swell and, together with the above flavonols and their glycosides, stimulate the S wall and increase its movement, causing intestinal mucosa. increase the moisture content of the fecal mass through At the same time, pectin, an auxiliary ingredient, acts as a lubricant between the fecal mass and the intestinal wall, further accelerating the progress of feces. As a comprehensive effect of such time effects, the food of the present invention exhibits an ideal effect as a dietary therapy food for chronic constipation.

(Experimental Example) In order to examine the effects of the food of the present invention, the following experiment was conducted on a total of 80 male and female subjects.

Human-1) [1) Test food Dajan variety plum (P, In5ititia) (7
) Extract extracted from dry matter with water (sugar content B8, moisture 27%)
) Fine kelp powder (300 mesh or less) per 1kg 50
0g and 3kg of water were added, stirred and mixed, filtered using gauze, and the filtrate was 100cm! After filling each glass bottle, 1
) A test beverage was produced by heat sterilization at 0°C for 30 minutes.

[21 doses Take 1001 orally after every meal.

[31 subjects (habitual constipation patients) 30 males (weight: 55-70 kg; age = 18-3
0) 30 girls (weight: 45-80kg; age: 18-
30) [41 Meals on the day of the experiment Breakfast 8:30 Butter, strawberry jam, milk scramble, sautéed broccoli lunch 12:30 Spicy boiled sardines tofu, small turnips, cooked rice with raw shiitake mushrooms Dinner 19:00 Beef stew with spinach and pine mushrooms Salad rice [51 intake, arbitrary amount 1 - 1 [1] Condition of defecation on the day of intake (test day) and the next day Note) Constipation: unable to defecate, normal: able to defecate naturally and comfortably, soft stool: feces are slightly fluid Diarrhea: watery stool (marked below) [2] Defecation volume The current standard defecation volume for Japanese adults (18-30 years old) is 1.
It is thought to be about 100 to 150g per serving, so 150g
If we consider the number of people who defecated more than g (27 boys; 25 girls) as a valid example, then the above food will be effective for 80% of boys and about 83 girls.
It is estimated that the effect was 87% on average for both men and women. Incidentally, since the number of soft drinkers accounted for more than 80%, the food in this example can be expected to have a sufficient effect on the majority of people even if the amount of intake is reduced to a local level.

(Example) Hereinafter, specific examples of the production of the invented food will be shown by way of examples, but these examples are of course for illustrative purposes only, and the connotation of the spirit of the invention.
It does not specify the extension.

! ULL (Beverage; Part 1) 1 kg of dried fine powder of brown algae (less than 300 mesh) and 2 kg of sugar, 4 each of fresh grapes, plums, and figs
10 kg of filtrate obtained by cutting into small pieces and squeezing using a small filter press, and 10 kg of water, premixed with a homomixer to adjust the precision to 14 and Pl (6), and then mixed with a homogenizer. This homogenized liquid was then filled into a can with an internal capacity of 200 μl, and 1)
The mixture was heat sterilized at 0-120°C for 30 minutes to obtain a laxative drink. By drinking one can of this beverage every day,
You can expect comfortable bowel movements.

1 pot 1''(Beverage; Part 2) In the previous example, 10 kg of the paste obtained by boiling the mashed fruit under reduced pressure was used instead of fruit juice, and the amount of water was increased to 20 kg. A laxative drink was obtained in the same manner.

``Shinden 1'' (spread for bread) 1 kg of fine powder of brown algae (less than 300 mesh) and mixed dried fruits of figs, plums, and grapes (moisture: 25 to 2
7%, sugar content 68-75), add 3 kg of water, soak with a silent cutter, filter, and add 15 g of fatty acid monoglyceride and 30 kg of Marga and phosphorus to the mixture, and mix in a kneading machine. After heating and emulsifying, the mixture was cooled and solidified in a refrigerator (inner temperature: 1 to 3°C) to obtain a bread spread.

￥LJLI (Bread Spread Part 2) 1 kg each of fresh figs, grapes, and plums were washed with water, chopped for 15 minutes using a high-speed cutter, and then filtered through a 100-mesh filter to obtain approximately 1.5 kg. .

Δ To 1 kg of the above filtrate, add 1 kg of water, 50 g of sugar, 200 g of finely powdered kelp (300 mesh or less), 5 g of salt, and 6 g of citric acid, and process in a homomixer for 10 minutes JIL-1
-Cation 1. (Quantum of Ia 71) + r - The resulting homogenate was heated to a temperature of 80 to 9 in a double pot using steam as a heat source.
Boil at 5°C, and when the total amount has decreased to 1.85 kg, add 30 g of pectin and boil further until the total amount is 1.85 kg.
When the weight reached 8 kg, heating was stopped, and the bottle was immediately sealed in a glass bottle and left to stand. This product is a delicious food product with reasonable consistency as a bread spread.

(Effects) According to the present invention, a beneficial health food that can reliably improve chronic constipation when ingested as part of a normal meal can be provided, and therefore has a favorable effect on improving the health of the people. is obtained.

Claims (4)

[Claims] (1) Alginic acid; essential constituents include flavonols or glycosides thereof selected from the group consisting of kaempferol, quercetin, and isoquercetin, and edible alkali metal and/or alkaline earth metal ions and/or salts. Laxative food as an ingredient. (2) Alginic acid; selected from flavonols or their glycosides selected from the group consisting of kaempferol, quercetin, and isoquercetin, and edible alkali metal and/or alkaline earth metal ions and/or salts. 2. The food according to claim 1, wherein the ingredients are pieces or powders or aqueous extracts of natural plants containing these ingredients. (3) The food according to claim 1, which contains pectin as an auxiliary ingredient. (4) The food according to claim 1, wherein the pectin is a piece or powder of a natural plant containing the present substance, or an aqueous extract.