JPS61183227A - Intestine-controlling food - Google Patents

Abstract

PURPOSE:To provide an intestine-controlling food containing extract and/or powder of KIDACHI-ALOE (Aloe arborescens) and/or HABUSO (Cassia torosa) as essential component. CONSTITUTION:KIDACHI-ALOE (a fleshy perennial low plant of Liliaceae family) and/or HABUSO (annual grass of Leguminosae family; aboveground part except for seeds; the aboveground part except for seeds of HOSOHABUSO (Cassia sophera), EBISUGUSA (Cassia obtusifolia), etc. which are family of HABUSO can be used suitably for the purpose) is washed e.g. by bleaching, cut to fine pieces, and freeze-dried, or is dried immediately after washing (by spontaneous drying, or hot-air drying), and pulverized. The objective intestine- controlling agent free from side effects can be produced by using the crushed product as an essential component. The content of the component in the composition is >=40wt%. It can be administered in the form of refreshing beverage, particle, granule, pill, powder, etc., at a dose of 500-10,000mg (powdery extract) per dose. The agent is effective to mildly stimulate the peristaltic movements of the intestines.

Description

[Detailed description of the invention] (Technical field to which the invention pertains) This invention relates to an intestinal regulating food, and its purpose is
Aroe arborescenes Mill) and/or Cassia nomama l1o
An object of the present invention is to provide an intestinal health food characterized by containing an extract and/or a pulverized product of (n.da) as an essential ingredient.

(Prior art and its disadvantages) Many people suffer from constipation symptoms due to recent changes in eating habits and overeating of old-tasting snacks and high-carbohydrate foods.

In particular, even though there are no particularly abnormal symptoms in Kamiike Health, many people experience persistent constipation symptoms, which often interfere with their daily lives.

These conditions are called essential constipation, and constipation causes various symptoms such as fatigue, nausea, headaches, eye irritation, hot flashes, stiffness, lower back pain, and other systemic symptoms. Symptoms of diseases of the gastrointestinal tract, such as tongue coating, mouth irritation, loss of appetite, abdominal distension, gagging, and flatus, may also be observed.

These symptoms may lead to secondary intestinal obstruction or irritating heat flare, so early improvement is desirable.

However, it is said to be undesirable to use enemas or laxatives to defecate because they inhibit the natural spiral movement of the large intestine.

In order to improve such symptoms, traditional herbal medicines such as lokai (Cape aloe, Socotra aloe, Curaçao aloe, Natal aloe, parts of Bonpei aloe) or cerium (seeds of Habuso, Bohobuso, Ehisugusa) are often used. It had been.

These herbal medicines are very effective in inducing emotional movement in the intestines, and the reason is that these plants contain large amounts of barbaloin, anthraquinone derivatives, and isoglycosides, which induce emotional movement in the intestine. In this sense, it is a very effective laxative, but on the other hand, because of its strong action, it has a strong laxative effect and is often accompanied by diarrhea.It is also a substance that can eliminate the emotional movement of the intestines if used too much. Aloe emodin was converted into aloe emodin, which was not desirable because it had side effects such as menorrhagia, premature birth, and even miscarriage.

(Solution) In light of the above circumstances, the inventors conducted extensive research and found a substance that promotes the emotional movement of the intestines in an extremely effective and relaxing manner, and also found that this substance has no side effects. That is, this invention is based on Aroe arborescenes Mil.
l) and/or Cassia nomama
The present invention relates to an intestinal health food characterized by containing an extract and/or a pulverized product of L. l1onda) as an essential ingredient.

(Structure of the Invention) Aroe arbo used in this invention
rescenes Mill), Cape aloe, Socotraa Ife, Kif, Rathoa [Koni, Natalua [: Iko, Hon.
It is a shrub-like succulent perennial of Lily H, which is different from Ia L1, etc., and a part of this 41■monoji-1 can be suitably used in this invention.

Cassia noma used in this invention
Ma Ifonda) is an annual plant of the bean 1), and its parts used are the above-ground parts other than the seeds.

Bochweed (Cas), which is a related plant to this
sta tora Il,), Ebisuguza (C8ssi
a ohtus: f.

1iaL,) can also be suitably used in this invention.

In this invention, Aroe arb.
orescenes Mill) and/or Orescenes Mill)
C;hss'+a n.

By using the above-ground parts of mama l1onda) and related plants, the side effects of the conventional plants are eliminated.

Regarding this effect, according to the experimental knowledge of the present inventors, these plants contain halhaloin, anthraquinone derivatives, and isoglycosides, which are intestinal emotional movement inducing agents contained in lokai and cicada. Therefore, the plants and their parts used in this invention are considered to be free from these side effects.

By the way, Aroe arhorescenes (formerly 1) and /
Or Cassianomama 1lond
Based on the experimental knowledge of the present inventors, the reason why terrestrial i'71 (a) and related plants have the effect of inducing emotional movement in the intestine is based on the experimental knowledge of the present inventors. , probably contains a precursor of parhaloin and an1-laquinone of unknown structure, and this precursor is metabolized in the human body to produce parhaloin,
It is thought that it may become Anne 1 to Laquinon.

However, the structure of this precursor of parhaloin and an-1-heraquinone, whose structure is unknown, is currently being elucidated, and unfortunately, it is still unclear at present.

In this invention, these Aroear
In order to use plant ingredients of Cassia borescenes Mill and/or Cassia nomama 1londa and related species as essential ingredients of the intestinal health food according to the present invention, it is sufficient to carry out cleaning such as bleaching according to a conventional method. After going through the process, it is cut into pieces and then freeze-dried, or
Immediately after the washing process, dry (natural drying, pneumatic drying),
Thereafter, it is made into a pulverized product by a method such as pulverization.

Alternatively, after the above-mentioned washing and cutting process, leave it in water or a water-containing lower aliphatic alcohol at room temperature for about 1 day or night, or heat it at 40 to 80°C, preferably 50 to 70°C for 2 hours.
Extracted for ~4 hours, then filtered, and the filtrate was extracted at 173-1
The concentrated extract may be concentrated to about 50% to form a liquid extract, or this concentrated extract may be freeze-dried to form a powder.

In this invention, this Aroear
borescenes Mill)
Powders or concentrated extracts of sia noma it on da) may be optionally mixed in a ratio of 10-200:200-10 and added to the intestinal health food according to the present invention, or each of the following may be mixed independently. It's okay.

Further, if necessary, these may be prepared into a tea preparation according to a conventional method after the above-mentioned washing and thinning J steps.

In order to make the intestinal health food according to the present invention using powder or extract of such ingredients, at least 40% of the total content must be
The food may be prepared into any food form containing these ingredients.

Specific examples include soft drinks, powders, and fruit! They are powders, pills, powders, etc., and when they are prepared in such forms, other Mgifiers, sweeteners, thickeners, lubricants, flavorings, and excipients may be added as necessary. It is desirable to add

In addition, usage amount 1): II! j. The amount may be increased or decreased as appropriate depending on the degree of symptoms such as constipation, but as a guide, the amount used at one time for adults should be about 500 mg to 10,000 mg (extract powder).

(SJ Fruit) As explained above, the intestinal regulating food according to the present invention is prepared from Aroe arborescenes Mill.
) and/or Cassia nomama
It is an intestinal food that is characterized by containing an extract of G51 and/or a ground product of G51 as an essential ingredient, so it is very effective in inducing emotional movement in the intestines that conventionally had herbal medicines such as Rokai or G51. Although it contains large amounts of '2J+ halvaroin, anthraquinone derivatives, and isoglycosides, these side effects (even causing menorrhagia, premature birth, and miscarriage)
It has the effect of being an intestinal regulating food that eliminates side effects and can alleviate the emotional movement of the intestines.

Next, the effects of the invention will be made clearer by showing examples and test examples of the invention.

Examples 1 to 3 and comparative examples Kidachialoe frozen pulverized product 0.5g starch
0.2g lactose
0.3g Frozen crushed grass leaves 0.5g #
Powder 0.2g Milk *J7j
O, 3g Kidachi Aloe frozen pulverized product 0.2g Frozen grass leaves 0.3g starch
0.2g lactose 0.3g Comparative example (1) Cape aloe frozen ground product 0.5g starch
0.2g lactose
0.3g Comparative Example (2) Frozen and ground cornstarch 0.5g starch
0.2g lactose
0.3 g or more'' - 5 types of powders were prepared in a single dose of 1 g.

Test example 25 women (18 years old and up) with habitual constipation (essential constipation)
The subjects (45 years old) were divided into 5 groups with 5 people in each group, and each group was given one package of the above powder in the morning and evening for 4 weeks.

Symptoms before eating are shown in Table 1, and symptoms after eating are shown in Table 2.

Table 1: Severe symptoms refer to symptoms that do not induce the urge to defecate without taking any kind of laxative.

For severe cases, take laxatives several times every 2 to 3 weeks.

Mild symptoms include taking 2mg of laxative several times a month.

Table 2 (After 4 weeks) In Comparative Examples 1 and 2, those who experienced severe diarrhea discontinued the test midway.

As is clear from the results in the margins below, 'J
i Intestinal food! It is known that it has no side effects and has mild intestinal regulation.

Claims (1)

[Claims] (1) Aroe arborescens
Cassia es Mill) and/or Cassia
1. An intestinal health food characterized by containing an extract and/or a pulverized product of Nomama Honda) as an essential ingredient.