JPS6097946A - Carboxamide derivative, its production and remedy containing said derivative - Google Patents

Carboxamide derivative, its production and remedy containing said derivative

Info

Publication number
JPS6097946A
JPS6097946A JP20363283A JP20363283A JPS6097946A JP S6097946 A JPS6097946 A JP S6097946A JP 20363283 A JP20363283 A JP 20363283A JP 20363283 A JP20363283 A JP 20363283A JP S6097946 A JPS6097946 A JP S6097946A
Authority
JP
Japan
Prior art keywords
etc
formula
derivative
compound
caused
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP20363283A
Other versions
JPH0379336B2 (en
Inventor
Yoshinobu Arai
Tsumoru Miyamoto
Masaaki Toda
Original Assignee
Ono Pharmaceut Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceut Co Ltd filed Critical Ono Pharmaceut Co Ltd
Priority to JP58203632A priority Critical patent/JPH0379336B2/ja
Publication of JPS6097946A publication Critical patent/JPS6097946A/en
Publication of JPH0379336B2 publication Critical patent/JPH0379336B2/ja
Anticipated expiration legal-status Critical
Application status is Expired - Lifetime legal-status Critical

Links

Abstract

NEW MATERIAL:The compound of formula I (R1 is 5W15C straight or branched chain alkyl, alkoxy, etc.; R2 is H or methyl; R3 is OH, carboxyl, carboxymethyl, etc.; X is -CH= or N; n is 0, 1 or 2; the dotted line is double bond or single bond), its non-toxic salt and non-toxic acid addition salt.
EXAMPLE: o-[N-(p-Amylcinnamoyl)amino]phenylacetic acid and its sodium salt.
USE: Effective to the various allergic plumonary diseases, shock, etc. caused by leukotriene, and thrombosis, inflammation, etc. e.g. caused by the damage of the endothelium or intima of brain or coronary vessel.
PREPARATION: The compound of formula I can be produced by reacting the acid chloride of formula II with the amine of formula III.
COPYRIGHT: (C)1985,JPO&Japio
JP58203632A 1983-11-01 1983-11-01 Expired - Lifetime JPH0379336B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP58203632A JPH0379336B2 (en) 1983-11-01 1983-11-01

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58203632A JPH0379336B2 (en) 1983-11-01 1983-11-01

Publications (2)

Publication Number Publication Date
JPS6097946A true JPS6097946A (en) 1985-05-31
JPH0379336B2 JPH0379336B2 (en) 1991-12-18

Family

ID=16477256

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58203632A Expired - Lifetime JPH0379336B2 (en) 1983-11-01 1983-11-01

Country Status (1)

Country Link
JP (1) JPH0379336B2 (en)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191113A (en) * 1987-05-07 1993-03-02 Ono Pharmaceutical Co., Ltd. Cinnamoylamide derivatives
JPH0562724U (en) * 1992-01-31 1993-08-20 株式会社大井製作所 Support structure of the rotating lever
EP0579223A1 (en) * 1992-07-17 1994-01-19 Mitsubishi Chemical Corporation Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity
WO1999007670A1 (en) * 1997-08-05 1999-02-18 American Home Products Corporation Anthranilic acid analogs
WO1999007669A1 (en) * 1997-08-05 1999-02-18 American Home Products Corporation Anthranilic acid analogs
US6127392A (en) * 1997-08-05 2000-10-03 American Home Products Corporation Anthranilic acid analogs
WO2001007020A3 (en) * 1999-07-27 2002-09-19 Boehringer Ingelheim Pharma Carboxylic acid amides, medicaments containing these compounds and the use and production thereof
WO2005016870A1 (en) * 2003-08-14 2005-02-24 Smithkline Beecham Corporation 2-substituted benzoic acid derivatives as hm74a receptor agonists
WO2010089984A1 (en) * 2009-02-03 2010-08-12 日本曹達株式会社 Phenolic compound and recording material
JP5549781B2 (en) * 2011-05-31 2014-07-16 Dic株式会社 Liquid crystal alignment layer comprising cinnamic acid derivative and polymer thereof, and cured product thereof
WO2019196714A1 (en) * 2018-04-11 2019-10-17 华东理工大学 N-substituted acrylamide derivative as dhodh inhibitor, and preparation and use thereof

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1077936A (en) * 1964-09-08 1967-08-02 Smith & Nephew Substituted benzanilides
GB1088295A (en) * 1965-07-10 1967-10-25 Smith & Nephew Derivatives of alkanoic acids and methods for their preparation
US3549689A (en) * 1967-05-23 1970-12-22 Sandoz Ag Phenoxy-alkanoic acids
FR2164481A1 (en) * 1971-12-21 1973-08-03 Aries Robert Phenylacylamino phenylalkanoic acids - antiinflammatories antipyretics analgesics and antirheumatics
JPS4993335A (en) * 1973-01-18 1974-09-05
JPS50135047A (en) * 1974-04-16 1975-10-25
JPS511440A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Shinkihokozokukarubonsanjudotai no seizohoho
JPS511439A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Hokozokuamidokarubonsan no seiho
JPS511438A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Shinkihokozokuamidokarubonsanjudotai no seizohoho
JPS57106651A (en) * 1980-12-23 1982-07-02 Ono Pharmaceut Co Ltd 1,4-disubstituted benzene compound, its preparation, and inhibitor against leukotriene biosynthesis comprising it as active ingredient

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1077936A (en) * 1964-09-08 1967-08-02 Smith & Nephew Substituted benzanilides
GB1088295A (en) * 1965-07-10 1967-10-25 Smith & Nephew Derivatives of alkanoic acids and methods for their preparation
US3549689A (en) * 1967-05-23 1970-12-22 Sandoz Ag Phenoxy-alkanoic acids
FR2164481A1 (en) * 1971-12-21 1973-08-03 Aries Robert Phenylacylamino phenylalkanoic acids - antiinflammatories antipyretics analgesics and antirheumatics
JPS4993335A (en) * 1973-01-18 1974-09-05
JPS50135047A (en) * 1974-04-16 1975-10-25
JPS511440A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Shinkihokozokukarubonsanjudotai no seizohoho
JPS511439A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Hokozokuamidokarubonsan no seiho
JPS511438A (en) * 1974-04-18 1976-01-08 Kissei Pharmaceutical Shinkihokozokuamidokarubonsanjudotai no seizohoho
JPS57106651A (en) * 1980-12-23 1982-07-02 Ono Pharmaceut Co Ltd 1,4-disubstituted benzene compound, its preparation, and inhibitor against leukotriene biosynthesis comprising it as active ingredient

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191113A (en) * 1987-05-07 1993-03-02 Ono Pharmaceutical Co., Ltd. Cinnamoylamide derivatives
JPH0562724U (en) * 1992-01-31 1993-08-20 株式会社大井製作所 Support structure of the rotating lever
EP0579223A1 (en) * 1992-07-17 1994-01-19 Mitsubishi Chemical Corporation Carboxylic acid derivatives having 5 alpha-reductase inhibitory activity
WO1999007670A1 (en) * 1997-08-05 1999-02-18 American Home Products Corporation Anthranilic acid analogs
WO1999007669A1 (en) * 1997-08-05 1999-02-18 American Home Products Corporation Anthranilic acid analogs
US6127392A (en) * 1997-08-05 2000-10-03 American Home Products Corporation Anthranilic acid analogs
WO2001007020A3 (en) * 1999-07-27 2002-09-19 Boehringer Ingelheim Pharma Carboxylic acid amides, medicaments containing these compounds and the use and production thereof
WO2005016870A1 (en) * 2003-08-14 2005-02-24 Smithkline Beecham Corporation 2-substituted benzoic acid derivatives as hm74a receptor agonists
WO2010089984A1 (en) * 2009-02-03 2010-08-12 日本曹達株式会社 Phenolic compound and recording material
JP5258909B2 (en) * 2009-02-03 2013-08-07 日本曹達株式会社 Phenolic compounds and recording materials
US8529688B2 (en) 2009-02-03 2013-09-10 Nippon Soda Co., Ltd. Phenolic compound and recording material
JP5549781B2 (en) * 2011-05-31 2014-07-16 Dic株式会社 Liquid crystal alignment layer comprising cinnamic acid derivative and polymer thereof, and cured product thereof
JPWO2012165550A1 (en) * 2011-05-31 2015-02-23 Dic株式会社 Liquid crystal alignment layer comprising cinnamic acid derivative and polymer thereof, and cured product thereof
WO2019196714A1 (en) * 2018-04-11 2019-10-17 华东理工大学 N-substituted acrylamide derivative as dhodh inhibitor, and preparation and use thereof

Also Published As

Publication number Publication date
JPH0379336B2 (en) 1991-12-18

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