JPS6026082B2 - Composition of lipophilic cream - Google Patents

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention has a relatively high water content, is rich in water retention and retention, does not irritate the skin, has a good feel without being sticky, and has excellent storage stability. A moist feeling,
This invention relates to an improved lipophilic (water-in-oil type) cream composition that provides heat retention effect, affinity, anti-aging effect, and smoothness.

Conventionally, many lipophilic creams have been commercially available, but most of them have a relatively low water content and have a sticky and oily feel, while others have the feel of a hydrophilic (oil-in-water type) skin cream. There are few lipophilic creams that can cover and nourish the skin surface without removing moisture from the stratum corneum, and improvements have been widely desired by consumers. As a result of intensive research into the development of a lipophilic cream that has improved all of the above-mentioned drawbacks, the present inventor has finally succeeded in providing a lipophilic cream with the specific composition described below, and has demonstrated the unique oil-gelling ability of the pullulan fatty acid ester. , protection co.

The hydrocarbon properties, moderate hydrophilicity, and lipophilicity are well matched with the good emulsifying power and surface chemical properties of sorbitan fatty acid ester derived from natural products, making it possible to convert oily hydrocarbon oils in the coexistence of large amounts of water. It emulsifies uniformly and stably to form an extremely stable water-in-oil emulsion with excellent water and oil retention properties.
The present invention was completed after discovering that it gives a good feel (non-sticky, moist feel like a hydrophilic cream) without irritating the skin, and has outstanding anti-aging effects, smoothness, storage stability, etc. . That is, the present invention provides 1 to 1% by weight of pullulan fatty acid ester, 5 to 5% by weight of liquid or pasty fatty acid ester, 5 to 11% by weight of higher alcohol, and 5 to 5% by weight of a fatty acid ester based on the weight of the composition. ~2
This is a lipophilic cream composition containing solpitan fatty acid ester in an amount of 8 to 8% by weight.

In the pullulan fatty acid ester used in the present invention, the acyl group (fatty acid residue) in the ester group has a carbon number of 6 to 22 carbon atoms (more preferably 11 to 19 carbon atoms), and a degree of substitution of the acyl group. 0.1 to 3 (more preferably 0.5 to 2.5), number average molecular weight of 1 to 3
2 million (more preferably 100,000 to 1 million) is preferable.

An example thereof is the following general formula [11 (In the above formula, A is hydrogen or an RCO group, R is an alkyl group or alkenyl group having 6 to 22 carbon atoms, and n is the degree of polymerization.

However, at least one of A is an RCO group. ) can be exemplified by pullulan fatty acid esters.

Pullulan fatty acid esters are used singly or in combination of two or more, and the blending amount (hereinafter referred to as content) is 1 to 1% by weight based on the total weight of the prescription ingredients (hereinafter referred to as composition amount). %, preferably 2 to 8% by weight.
When it is less than 1% by weight, the storage stability of the composition tends to decrease, and when it is more than 1% by weight, the storage stability of the composition is poor and the lipophilic cream tends to have a poor feel on the skin.

Liquid or pasty aliphatic hydrocarbons are aliphatic hydrocarbons that are liquid or pasty at room temperature and are known as additive components of cosmetics, such as hydrogenated liquid paraffin, squalane, pristane, and polyisoprene. Preferred examples include oligomers of olefins having 3 to 12 carbon atoms, and hydrogenated products thereof.

More specific examples include liquid paraffin (light oil, medium heavy oil), squalane, synthetic squalane, pristane, oct-1 polymer (oil), dodecene-1 polymer (oil),
Examples include 2,6,15,19,23-hexamethyltetracosas, liquid polyisobutylene, liquid polyisobutene, betrolatum, and vaseline. The content of liquid or pasty aliphatic hydrocarbons is from 5 to 5% by weight, preferably from 10 to 4% by weight, based on the weight of the composition.
It is.

If it is less than 5% by weight, storage stability may deteriorate or phase inversion may occur easily, and if it exceeds 5% by weight, storage stability may be reduced, the oily feel may be too strong, and the moist feeling may be reduced. Easy to disappear.

Sorbitan fatty acid esters include higher fatty acid esters in which the alkyl group or alkenyl group of the acyl group has 11 to 21 carbon atoms (sorbitan esters of saturated fatty acids or unsaturated fats having 12 to 22 carbon atoms), and monoesters;
Sesquiesters and triesters are preferred.

The sorbitaso fatty acids may be used singly or in combination.

Its content is 5-2% by weight, preferably 8-1% by weight, based on the weight of the composition.

When the amount is less than 5% by weight, the stability of the composition decreases.

When the amount exceeds 2% by weight, the stability of the composition decreases and the feel during use tends to be poor. The higher alcohol has the following general formula [21ROH...
...'2} (R is an alkyl group or alkenyl group having 11 to 18 carbon atoms) is preferred, and is used singly or in combination of two or more.

Its content is 5 to 11% by weight, preferably 7 to 9% by weight, based on the weight of the composition. If it is less than 5% by weight, the stability of the composition tends to deteriorate, and if it exceeds 11% by weight, the condition of the composition tends to deteriorate and the stability tends to decrease.
The water content is from 8 to 83% by weight, preferably from 36 to 5% by weight, based on the weight of the composition. If it is less than 8% by weight, the cream tends to have a strong oily feel, and if it is more than 83% by weight, the stability of the composition tends to deteriorate.

The composition of the present invention is produced by condensing water heated to a homogeneous mixed melt (85 to 9 pi○) consisting of a required amount of pullulan fatty acid ester, liquid or paste aliphatic hydrocarbon, sorbitan fatty acid ester, and higher alcohol. It is manufactured by mixing it with Azusa to emulsify it, adding fragrances and preservatives, and cooling it to room temperature.

The composition of the lipophilic cream of the present invention is a cream-like lipophilic cream having a white paste-like hardness and an electric conductivity of 0, and is a synergistic combination of pullulan fatty acid ester and sorbitan fatty acid ester. The effect forms a uniform and stable water-in-oil emulsion, which has excellent long-term storage stability.
Even if stored for years, oil will not seep out, phase inversion will not occur, and water will not separate. It also has excellent water and oil retention properties, does not irritate the skin, gives a good feel (such as the moist feel of a non-sticky hydrophilic cream), and has excellent anti-aging effects, smoothness, moisturizing effects, and affinity. Therefore, its commercial value is extremely large. Examples of the present invention will be described below. Note that "part" means part by weight, and "%" means percent by weight.

Example 1 {1} Composition of lipophilic cream of the present invention 1 Pullulan stearate (pure part) (molecular weight 200,000) (degree of substitution 5) 4 parts 2 Polysobutene (pure part) 3 Kato 3 Setanol (pure part) 7 parts 4 Sorbitaso sesquioleate (pure) 8 parts 5 Fragrance, antifungal agent Appropriate amount 6 Water
5 foundations total 10 anchors {
2) Preparation of lipophilic cream composition Pullulan stearate was thoroughly mixed with polyisobutene, and then cetanol and sorbitan sesquioleate were added to prepare a homogeneous molten solution of 85 qo to 90 qo.

Next, mix water and antifungal agent and heat mixture 'B' to 85℃~9000℃.
- was prepared. Thereafter, the soybean paste is slowly added to the homogeneous molten solution, mixed, and cooled to room temperature. Thereafter, fragrance was mixed while stirring to obtain a lipophilic cream composition of the present invention. Example 21 Pullulan palmitate ester (pure) (average molecular weight 200,000, degree of substitution 2)
4 parts 2 Liquid paraffin (Seibold 70) (pure) 30 parts 3 Stearyl alcohol (pure) 9 parts 4 Sorbitan sesquioleate (pure) 8 parts 5 Fragrance, anti-fusing agent Appropriate amount 6 Water
48 copies total 10 bases {3' The manufacturing method of Example 2 is the same as Example 1.

'4} Example 3 1 Bullulan isostearate (average molecular weight 300,000, degree of substitution 1.5) 5 parts 2 squalane 3 anchor parts 3
Setanol 8 parts 4 Sorbitan sesquioleate 8 parts 5 Fragrance Anti-flashing
thin amount 6 water
48 parts total 10 base parts '5) The manufacturing method of Example 3 is the same as Example 1.

'6} Comparative Example: Lipophilic Cream Composition ■ Comparative Example 1 was carried out in the same manner as in Example 1 of the present invention, except that dextrin stearate was used instead of bullulan stearate.

(2) Comparative Example 2 was carried out in the same manner as Example 1 of the present invention, except that starch stearate was used instead of pullulan stearate.

(2) Comparative Example 3 was carried out in the same manner as Example 1 of the present invention, except that bullulan stearate was not used.

(2) Comparative Example 4 was conducted in the same manner as Example 1 of the present invention, except that sorbitan sesquioleate was not used.

■ Comparative Example 5 except that 2 parts of aluminum stearate was substituted for part of solpitan sesquioleate.
The same procedure as in Example 1 of the present invention was carried out.

{7) Next, the storage stability, appearance, and sensory tests (moist feeling, heat retention effect, familiarity with the skin, anti-aging effect, etc.) of the compositions of the invention examples and comparative examples were investigated.

The results are shown in Table 1. In addition, the appearance in Table 1 is observed by naked eye, and the storage stability is determined by the condition when stored in a greenhouse for 6 months with a cycle of 2 weeks at -10℃ and 2 weeks at 45qo. When it was separated, it was unstable, but the color and odor did not change and the uniform cream state was stable. The sensory test was conducted with a panel of 20 women, and the number is the number of people who answered that the product was good.

Table 1 (Note) Microscope Test Each sample was observed using an Olympus microscope at a magnification of 400 times. Uniform indicates that the particles are neatly arranged, and non-uniform indicates that the particles are not arranged.

Dye method When each sample is placed on a watch glass (approximately 1 tare) and the dye of Sudan M (red No. 225) is sprinkled on top of the sample, the state in which the dye spreads neatly is called a red beam, and the state in which it spreads slightly is called a red beam. The state where the stain did not spread at all was defined as clear beam, and the state where it did not spread at all was defined as unstained.

situation W No○...Indicates lipophilic state.

○/W... Indicates a hydrophilic state.

As is clear from this result, Examples 1, 2, and 3 of the present invention
The composition of , is significantly superior in lipophilicity, storage stability, and functionality compared to the composition of the comparative example.

Further, even if similar components are used in place of the constituent components of the present invention, a good lipophilic cream composition cannot be obtained. Example 4 The same procedure as in Example 1 of the present invention was conducted except that the content of pullulan stearate was changed as shown in Table 2.

The results are shown in Table 2. Table 2 and Table 3 show the results of the sensory test.

Table 3 As is clear from the results in Table 2 and Table 3, the content of pullulan fatty acid ester is 1 to 10%, preferably 2 to 8%.
%.

Example 5 The same procedure as Example 1 of the present invention was carried out except that the content of polyisobutene was changed as shown in Table 4.

The results are shown in Table 4. Table 4 As is clear from the results, the content of polyisobutene is 5% to 50%, preferably 10% to 40%.
This composition is desired as a commercial gel.

Example 6 The same procedure as in Example 1 of the present invention was carried out except that the content of cetanol was changed as shown in Table 5.

The results are shown in Table 5. Table 5 As is clear from the results, when the content of cetanol is less than 5% or more than 11%, the lipophilic cream composition is unstable.

Example 7 The same procedure as in Example 1 of the present invention was carried out except that the content of sorbitan sesquioleate was changed as shown in Table 6.

The same procedure as in Example 1 of the present invention was conducted except that the results were changed as shown in Table 6.

The results are shown in Table 6. Table 6 As is clear from the results, the content of sesquioleic acid sorbitan ester is 5 to 20%, preferably 8 to 17%.
% is good as a new oil-based cream composition.

Example 8 Instead of polysopten, liquid paraffin, squalane, synthetic squalane (Lion Oil KK product Pamit 4)
0), octene-1 polymer (viscosity 30M, wisteria value 0.
01, pour point -4 pi 0, this is a polymerized oil of Q-olefin), a polymer of dodecene-1 (viscosity 19 PS, acid value 0.
01, pour point -4 0, this is polymerized oil of Q-olefin) pristane, 26.15.19.23-hexamethyltetracosane, liquid body IJ isobutylene (viscosity of 10 and F is 2ST, average molecular weight 320 odorless) liquid polyisobutene (10-valent viscosity is 1ST, average molecular weight 3 scales, no odor), LIPO-LUBR2 eaves (Lion oil product: Q-olefin polymerized oil, regular viscosity 17.87/37,
The same procedure as in Example 1 of the present invention was carried out except that Stoke's temperature was 8°C, specific gravity was 0.818, and viscosity index was 124).

As a result, like the lipophilic cream of Example 1, both compositions formed uniformly stable water-in-oil emulsions, and remained stable even after storage for 6 months, with no abnormalities observed. The results of the sensory test were also good.

Example 9 Average molecular weight 20 instead of pullulan stearate
The same procedure as in Example 1 was carried out except that pullulan lauric acid ester, oleic acid ester, capric acid ester, oleic acid ester, and behenic acid ester of pullulan with a degree of substitution of 1.5 were used.

As a result, both compositions formed uniform water-in-oil emulsions similar to Example 1 and the lipophilic cream, and were stable even after 6 months, with no abnormalities observed. In addition, the results of the sensory test were also good. Example 10 Solpitan sesquioleate instead of sorbitan sesquioleate,
The same procedure as in Example 1, Example 2, and Example 3 was conducted except that sorbitan trioleate, sorbitan monostearate, sorbitan distearate, sorbitan sesquistearate, and sorbitan monobehenate were used.

Claims (1)

[Claims] 1 Based on the weight of the composition, 1 to 10% by weight of pullulan fatty acid ester, 5 to 50% by weight of liquid or pasty fatty liquid ester, 5 to 11% by weight of higher alcohol, and 5 to 20% by weight of Sorbitan fatty acid ester and 8
A lipophilic cream composition containing ~83% water by weight.