JPS60158863A - Production of light blocking syringe barrel - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a method for manufacturing a light-shielding injection container, and more particularly to a method for manufacturing an injection container such as an ampoule or a vial that has a light-shielding property without using a special container.

Conventionally, light-shielding materials such as injection-engraved cyampuric materials, which are unstable to light, have been generally carried out by storing them in special light-retaining packaging containers.

However, in the case of using such a container storage method, it is necessary to remove the container from the container in any case, which makes it difficult to handle it when it is used, and it also has the disadvantage of high cost. It had a

On the other hand, it may be possible to use colored glass to provide light-shielding properties to the cyanpur itself, but this is not commonly used due to the problem of colorant elution and the difficulty of inspecting foreign objects through colored glass. This is the reality.

Therefore, the inventor of the present invention has conducted various studies in order to solve these conventional drawbacks, and has found that if a heat-shrinkable light-shielding film is used and tightly coated on a container such as an angle, it can be made to have a light-shielding property by itself. The present invention was completed based on the discovery that an injection container that is convenient to handle can be obtained.

That is, the present invention is a method for producing a light-shielding injection container, which comprises covering the injection drug container with a heat-shrinkable light-shielding film and then heating the film to bring the film into close contact with the container.

In the present invention, an injectable drug container refers to a container that accommodates various injectable drugs such as ampoules, Bayer, and Silkol.

Furthermore, in the present invention, a heat-shrinkable light-shielding film is a colored film that has the property of shrinking when heated, such as: Films such as riethelene, salt, vinyl chloride, and propylene are listed, and their thickness is 10 to 200 μm.
degree is preferred. Similarly, the color of the film may be appropriately selected from red, orange, yellow, green, etc., which can block light rays that adversely affect the drug content.

To carry out the present invention, it is first necessary to cover an injectable drug container with a heat-shrinkable light-shielding film.

The specific method of coating here does not matter, but in order to achieve more precise adhesion by heating, it is necessary to prepare a package compatible with the injectable drug container to be coated with a heat-shrinkable light-shielding film in advance. Particularly good results are obtained by coating with

The form of this package may be a so-called cylindrical integrated type with an open top or bottom (see Figures 1 and 2), or a top package and a bottom package, or a left package and a right package. It may also be of a separate type, such as a package for a car (see Figures 3 to 5). In the case of partially releasable molds, the order of coating does not matter.

Incidentally, the one-piece type has the advantage that the next heat shrinking process is only required once, and the separate type has the advantage of being able to provide a more reliable and beautiful adhesion coating; However, if the package is molded separately so that no overlapping portions are formed during coating, there is an advantage that the heat shrinking process can be done only once, as in the case of an integrated type.

In addition, when the method of the present invention is to be carried out using an easy-cut ampoule, perforations are formed in the packaging body corresponding to the cut portion, or a method is used to prevent the formation of an overlapping portion at the cut portion. It is advantageous to use separately molded packages, and especially in the latter case there is also the advantage that only one heat shrinkage step is required.

In the present invention, a heat treatment is performed after the coating step, and the heating is usually performed at 20 to 100°C for about 0.1 to 60 seconds.

Through such heat treatment, the heat-shrinkable light-shielding film coated on the injectable drug container shrinks and comes into close contact with the outer wall surface of the container,
A light-shielding injection container is obtained.

As described above, according to the present invention, it is possible to form a light-shielding film layer in close contact with the outer wall surface of a container, so that it is possible to provide an injection mixer having a light-shielding effect in the container itself.

Furthermore, since the present invention can be carried out after inspection for foreign objects, there are no drawbacks such as those associated with the use of colored glass.

Furthermore, since the present invention uses a film adhesive coating method, it can be manufactured at a much lower cost than conventional container-type containers, and there is no problem with various types of printing after adhesive coating.

Hereinafter, examples of the present invention will be given and further explained with reference to the drawings.

Example 1 (FIG. 1) The tested EC-Cut Ansol 1 was placed in a cylindrical heat-shrinkable light-shielding film package 3 having an upper ml opening and heated to obtain a light-shielding ampoule. Similarly, the package 3 used was one in which perforations 4 were formed in the corresponding part of the cut part of Ansol.

Example 2 (Fig. 2) Cylindrical heat-shrinkable light-shielding film package 5 having a lower opening
A light-shielding ampoule was obtained in the same manner as in Example 1 except that .

Example 3 (Fig. 3) Using a heat-shrinkable light-shielding film package 6 separated into upper and lower parts so that a coating-retaining polymerization part is formed in the corresponding part of the lower part of the ampoule, the upper part is first placed in the inspected easy-cut ampoule 1. The package 6a was placed on it and heated, and then the bottom package 6b was placed on it and heated to obtain a light-shielding angle.

The upper packaging body 6a used was one in which perforations 4 were formed at a portion corresponding to the cut portion of the ampoule.

Example 4 (Fig. 4) Light shielding was carried out in the same manner as in Example 3, except that the left and right heat-shrinkable light shielding film packaging bodies 7 were used, which were separated into left and right parts so that a coating-retaining polymerization part was formed at the angle and the vertical side. Got a sex ampoule.

Example 5 (Fig. 5) Using a heat-shrinkable light-shielding film package 8 separated into upper and lower parts so as to prevent the formation of a coating-retaining polymerized part in the corresponding part of the cut part of the Ansol, the upper and lower parts were placed in the inspected E-Cut ampoule 1. Both sides were covered and heated to obtain a light-shielding ansol.

[Brief explanation of the drawing]

1 to 5 are schematic process diagrams each showing an example of the present invention. 1----- Ampoule 2----- Easy cut part 4--1--Perforation 3.5, 6, 7.8 ---1--Heat-shrinkable light-shielding film package H--- -Applicant with more than one fever Toshio Takano, Patent Attorney, Kanto Ishiki Pharmaceutical Co., Ltd. Ji,'!・5. ; Patent attorney Nobuo Ono, - Emperor:! ,・,: (1 H-f;,:6',,',',',-LJ1.-ζ

Claims (1)

[Claims] 1. A method for manufacturing a light-shielding injection container, which comprises covering an injection drug container with a heat-shrinkable light-shielding film and then heating the film to bring the film into close contact with the container.