JPS6014204Y2 - Inhaled liquid testing device - Google Patents

Description

[Detailed Description of the Invention] This invention relates to an inspection device used for testing biological fluids and other liquids.

The rheological properties of liquids change when a living body becomes ill or the environment changes, so testing the blood can be used to diagnose diseases.

For example, in the case of acute inflammation, plasma viscosity increases because the concentration of fibrinogen also increases due to the increased viscosity of the plasma.

When the viscosity of blood changes, the propagation speed of ultrasound in blood,
Since it affects the amplitude attenuation rate, by measuring these ultrasonic physical properties, it is possible to quantitatively diagnose living organisms.

Furthermore, changes in the proportions of proteins and glycoproteins in blood and synovial fluid affect dielectric properties, making it possible to diagnose symptoms.

In this way, it is already known that the physical properties of biological fluids can be examined to diagnose the symptoms of a living body, but much development still needs to be done in order to put this into practical use. desired.

For example, with conventional testing devices for biological fluids, etc., there are problems such as when biological fluids collected from a subject are transferred to the testing device, the biological fluids come into contact with air and deteriorate in quality, and the amount to be collected is also large. It was difficult to measure immediately on site.

To solve this problem, a syringe-type liquid testing device is sometimes used.

This syringe-shaped liquid testing device was constructed so that an electrode was attached to the syringe-shaped cylinder piston, and the pH of the test liquid inhaled into the cylinder was immediately measured using this electrode. New patent application announcement No. 1105
(See Publication No. 7 and Utility Model Application Publication No. 344 of 1939).

However, such conventional liquid testing devices cannot test the ultrasonic physical properties such as the ultrasonic propagation velocity and attenuation rate of the test liquid, and cannot measure the ultrasonic propagation distance of the test liquid in the cylinder. Therefore, it was difficult to accurately and quickly measure their ultrasonic physical properties.

This idea was developed in view of the above circumstances, and when testing the ultrasonic physical properties of a liquid, the amount of sampled liquid to be tested is small, and the liquid to be tested does not come into contact with air. It is an object of the present invention to provide an inhaled liquid testing device that can perform accurate testing immediately and on-site, and that can be easily applied to testing biological fluids and other fluids.

In response to this purpose, the inhaled liquid testing device of this invention is
a cylinder having a liquid suction port portion that engages a hollow needle-like suction needle at its tip; and a variable volume that is slidably engaged in a fluid-tight manner within the cylinder and capable of storing a test liquid between the cylinder and the cylinder; a piston that partitions a space, configured to inhale the test liquid into the space through the suction needle and the liquid suction port, and an ultrasonic sensor disposed within the space; The ultrasonic sensor consists of a pair of ultrasonic sensor members, one ultrasonic sensor member is fixed to the cylinder, the other ultrasonic sensor member is fixed to the piston, and the cylinder and the ultrasonic sensor member are fixed to the piston. It is characterized by being equipped with a micrometer that measures the distance traveled relative to the piston.

The details of this invention will be explained below with reference to the drawings showing one embodiment.

In the figure, reference numeral 1 denotes an inhaled liquid testing device, and the inhaled liquid testing device 1 includes a cylinder 2 .

In the cylinder 2, a cylindrical main body 3 and a tapered cylindrical suction port 4 are connected with a shoulder 5 as a boundary, and a hollow needle-like suction needle 6 is engaged with the suction port 4.

A piston 7 is slidably engaged in a fluid-tight manner within the body 3 of the cylinder 2, and a stem 8, which is fixed to the piston 7, extends outside the body 3 of the cylinder 2.

The cylinder 2 and the piston 7 cooperate to define a fluid-tight variable volume space 9 within the cylinder 2.

A sensor 10 is arranged within the space 9.

The sensor 10 can be any sensor, such as an ultrasonic receiver, a pair of electrodes, or a chemical component detector, depending on the item to be tested.

In this embodiment, an ultrasonic transducer is used as the sensor 10.

That is, the transmitter 11 of the ultrasonic receiving transmitter is connected to the cylinder 2.
The receiver 12 is fixed to the tip of the main body 3, that is, adjacent to the shoulder 5, while the receiver 12 is fixed to the tip of the piston 7,
The lead wire 13 passes through the stem 8 of the piston 7 and is led out to the outside, and the lead wire 14 passes through the cylinder 2 and is led out to the outside.

As the oscillator 11, a PzT, crystal oscillator, etc. of IMHz to several MHz is used.

A through hole 15 is formed on the side of the transmitter 11, and the liquid in the suction port 4 can flow into the space 9 through the through hole 15.

Further, a micrometer (not shown) is provided between the main body 3 of the cylinder 2 and the stem 8 of the piston 7.

When testing a liquid using the inhaled liquid testing device configured in this way, the inhalation needle 6 is inserted into the source of the biological or other liquid to be tested, and then the piston 7 is manually retracted. Then, the test liquid flows into the space 9 through the suction needle 6, the suction port 4, and the through hole 15 of the transmitter 11.

The thickness of the inflowing test liquid is measured by the micrometer.

Next, the ultrasonic waves transmitted from the transmitter 11 are transmitted through the test liquid and received by the receiver 12, thereby making it possible to measure the ultrasonic physical properties of the test liquid.

Since the propagation speed and amplitude of ultrasonic waves are attenuated in a liquid, the distance between the cylinder and the piston is measured to determine the volume of the liquid to be tested or the distance between a pair of ultrasonic sensor members, that is, the ultrasonic propagation distance. Making it detectable is extremely important in order to improve the testing accuracy of the test liquid.
The micrometer mentioned above makes it possible to detect this ultrasound propagation distance.

The above is a transmission type embodiment, but if a metal plate is used instead of the receiver 12, the ultrasonic waves are reflected by the metal plate and received again by the transmitter, so a so-called reflection type inspection device is also possible. be.

In addition, an electrode field is applied as a sensor member, and an alternating current electric field with different frequencies is applied between the electrodes, and the complex dielectric constant ==,
/ -1,III can be measured.

Note that by appropriately selecting a sensor, it is possible to measure other physical properties and chemical components of biological fluids, and it is also possible to measure liquids other than biological fluids in the same way.

As described above, according to the inhalation fluid testing device of this invention, a small amount of biological fluids such as blood, joint fluid, and other test fluids can be collected from a person to be measured, and measurements can be carried out immediately on site in that state. It also enables accurate and rapid measurement of ultrasonic physical properties and chemical components without exposing the test liquid to air or contaminating it.

BRIEF DESCRIPTION OF THE DRAWINGS The figure is an explanatory longitudinal cross-sectional view showing an inhalation liquid testing device according to an embodiment of the present invention. 2...Cylinder, 6...Inhalation needle, 7
...Zeston, 10...Sensor, 11
...Sender, 12...Receiver.

Claims (1)

[Scope of utility model registration request] a cylinder having a liquid suction port portion that engages a hollow needle-like suction needle at its tip; and a variable volume that is slidably engaged in a fluid-tight manner within the cylinder and capable of storing a test liquid between the cylinder and the cylinder; a piston that partitions a space, configured to inhale the test liquid into the space through the suction needle and the liquid suction port, and an ultrasonic sensor disposed in the space; The ultrasonic sensor consists of a pair of ultrasonic sensor members, one ultrasonic sensor member is fixed to the cylinder, the other ultrasonic sensor member is fixed to the piston, and the cylinder and the ultrasonic sensor member are fixed to the piston. An inhalation liquid testing device characterized by being equipped with a micrometer that measures the distance traveled relative to a piston.