JPS60126211A - Cosmetic - Google Patents

Abstract

PURPOSE:A cosmetic having improved affinity, permeability, dispersibility, and wetting properties to the skin, high safety and stability free from problems of color and smell, containing a purified liquid lanolin and/or hydrogenated purified liquid lanolin having high content of ester component. CONSTITUTION:A cosmetic comprising purified liquid lanolin and/or hydrogenated purified liquid lanolin having >=90wt% content of ester component. In the purified liquid lanolin, color and smell of lanolin, defects of adhesivity, problem of rancidity with time, allergic phenomena considered to be caused by aliphatic alcohol components, etc. are extremely improved. The purified liquid lanolin is obtained by packing an adsorbent such as silica gel, acid clay, etc. into a column, feeding liquid lanolin to it, developing it with n-hexane, etc., collecting partially an ester component. The purified liquid lanolin is further hydrogenated in the presence of Cu or Pd at <=200 deg.C, to give hydrogenated purified liquid lanolin.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention has excellent skin affinity, permeability, diffusibility, and wettability, and is highly safe and stable.

Furthermore, it is an object of the present invention to provide a new cosmetic material that has no problems in terms of sensory aspects such as color and odor.

Traditionally, lanolin has an affinity for the skin.

@ Shigashi was one of the raw materials used in various cosmetics such as creams, 2 lipsticks, and 7 Ace powders because of its high wettability, water-holding power, and emulsifying power.

In recent years, the use of lanolin has been avoided due to problems with color, odor, and adhesion, as well as the problem of rancidity over a long period of time, as well as allergic phenomena thought to be caused by the aliphatic alcohol component.

On the other hand, as a raw material to replace 2-noline, liquid 2-noline, which is obtained by removing the solid ester content from lanolin by vacuum distillation or solvent fractional crystallization, is also commonly used. Compared to lanolin, crystal is less sticky, has better miscibility with other oils, and has better permeability, diffusivity, and softening effects on the skin. However, liquid lanolin often contains impurities in lanolin in a more concentrated state than lanolin due to its manufacturing method, and as a result, it is colored 2.
Either the odor is not improved or the problem of allergies remains. And these problems.

It has been difficult to solve this problem even by using methods commonly known as lanolin purification methods such as a water medium method and a solvent method.

Furthermore, ester compounds of sterols (mainly cholesterol), which are known as higher alcohol components in 2-Norine, and branched or unsaturated fatty acids are also known as -m cosmetic oils, but they were very expensive. .

Therefore, as a result of intensive research to solve the conventional problems as described above, the present inventor has determined that polar substances present in liquid lanolin (for example, lanolin alcohol) can be extracted from liquid lanolin using a purification method such as column fractionation. , lanolin fatty acids, etc.)
It has been shown that by removing as much as possible and increasing the content of the ester component by 90% or more KV, the above-mentioned problems such as color, odor, and allergies can be significantly improved without losing the excellent properties of liquid lanolin. This is what I found. Furthermore, the present inventors have investigated the unsaturated bonds of the sterol moieties and unsaturated fatty acids such as oleic acid present in trace amounts in the purified liquid lanolin obtained under conditions that do not affect the ester bonds. The present invention was completed based on the discovery that the stability (especially oxidation stability) is further improved by hydrogenation.

The present invention relates to a cosmetic containing purified liquid lanolin and/or hydrogenated purified liquid lanolin with an ester component content of 90% or more.

Purified liquid lanolin or hydrogenated purified liquid lanolin applied to the present invention can be obtained by the following method.

That is, for example, silica gel, acid clay, activated clay.

A column is filled with an adsorbent such as activated alumina, and liquid 2-noline is supplied to it, followed by Kn-hexane, petroleum ether,
The ester component is separated by development using a low polar organic solvent such as cyclohexane or ethylenyl. In addition, when using an adsorbent with a large adsorption capacity such as activated alumina, good results can be obtained by setting the polarity of the organic solvent slightly higher and increasing the development speed to prevent decomposition of the ester component. Next, the expanded filler (adsorbing polar substances) becomes reusable by passing methanol through it after use.

Furthermore, the obtained purified liquid lanolin (ester is the main component)
ft in the presence of a catalyst such as copper or palladium,
Hydrogenation is carried out at a temperature of 200°C or lower to obtain hydrogenated purified liquid lanolin.The hydrogenation in the present invention removes the sterol moieties present in the purified liquid lanolin and trace amounts of non-containers such as oleic acid. The purpose is to selectively add hydrogen to unsaturated bonds in saturated fatty acids.

For example, it is completely different from the reduced lanolin (hydrogenated lanolin) described in the cosmetic primordium, which cleaves the ester bond under strong conditions (catalytic reduction, metallic sodium) and is reduced to higher alcohols and sterols. It is something.

Next, a specific method for obtaining purified liquid lanolin will be shown with a production example.

Production Example 1 An adsorption tower was filled with 100 parts of silica gel, and a sample prepared by dissolving 10 parts of liquid Dinorif in 50 parts of a mixed organic solvent of n-hexane:ethyl ether = 10:1 was supplied to the adsorption tower. Develop using 100 parts and collect the eluate. When the solvent was removed from the resulting eluate, a pale yellow, low viscosity liquid oil was obtained. Yield: 54. B Chi.

When the crystal was checked by thin layer chromatography (TLC), spots were found only in the ester portion, and no spots corresponding to alcohol or fatty acids were found.

Further, the purity was measured by gas chromatography Ic)K, and the ratio of ester component to polar substance component was 98:2. Physical property values: Acid value: 0.15, Hydroxyl value: 8. 55, saponification value: 97.8 Purified liquid lanolin in the present invention and hydrogenated purified liquid lanolin with improved oxidation stability (properties and physical properties are approximately the same as purified liquid lanolin)
Lanolin is a product that removes most of the polar substances that are said to be the cause of coloring, odor, and allergic phenomena, and maintains the excellent properties that liquid lanolin originally had, so it has various functions. This makes it possible to obtain outstanding cosmetics.

The dosage forms of cosmetics that are usually blended here include creams, milky lotions, ointments, foundations, hair products, lotions, soaps, and various other cosmetics, and can be used in a wide range of applications. Regarding the blending amount of 7j, it can be blended in the same manner as liquid lanolin has conventionally been blended.For example, in creams, it can be blended in an amount of 0.1 to 20% by weight. Furthermore, it is naturally possible to use it in combination with other commonly used cosmetic oils and emulsifiers, and there is no need to impose any particularly limited manufacturing methods.

Next, the dud F! The purified liquid lanolin obtained by AK has few problems of coloring and odor, and the emollient effect it exhibits when blended into cosmetics was evaluated and the results are shown below.

(1) Hue value The hue value (
Gardner), commercially available products are 6 to 9
On the other hand, the products of the present invention were in the range of 3 to 5.

(2) Olfactory test Using the purified liquid lanolin of the present invention as a standard, a comparative odor test was conducted on commercially available liquid lanolin (manufactured by Yoshikawa Oil Co., Ltd.) and its diluted products using 25 panelists.Table 1 shows the results of an odor comparison test conducted using 25 panelists.
Shown below. As a diluent, dimethyl silicone (Shin-Etsu Silicon KF 96-5000) 'ij-7t+
Table 1 Liquid lanolin olfactory evaluation (n=25) (3) Transepidermal water loss for various oils containing purified liquid lanolin of the present invention
Loss, abbreviated as 'r, WL) (1nv
iv), the results showed that purified liquid lanolin (product of the present invention), liquid lanolin (vaseline (hydrocarbon)), olive oil (triglyceride), and cetyl inoctoate (ester) were suppressed in this order. The purified liquid lanolin of the present invention has lower T and WL values than other various oils, and evaporation of water from within the epidermis is relatively suppressed.

(4) Note: In the milky lotion of Example 3, the purified liquid lanolin of the present invention was used in place of other conventional oils (replaced with a two-week continuous use test), and the results were as shown in Table 1-2. The values in Table 2 indicate the condition of the skin after repeated use for a panel of subjects with dry skin and normal skin.
They were evaluated using the following evaluation criteria.

Table - 2 repeated use test As is clear from the various evaluation test results, the purified liquid lanolin according to the present invention has few problems of coloring and odor, has excellent emollient effect, and is safe and stable due to the removal of polar substances.・When the oil of the present invention is blended into cosmetics, as shown in the repeated use test in Table 1-2, the skin becomes moist, soft, and has an increased sense of transparency due to repeated use. The typical result was that the so-called ``makeup adhesive'' improved as a result.

Next, examples will be shown. Incidentally, the blending ratio is in weight %.

Example 1 Nutritional Cream Purified liquid lanolin 4.8 Hydrogenated purified liquid lanolin 2.0 Stearic acid 8.5 Beeswax 3.8 Cholesterol 2.0 Synthetic wax 3.0 Inglovir palmitate 13.0 Liquid paraffin 12゜0 Bili Doxin dioctanoate 0.5 Pholoxyethylene ■Behenyl ether 3.7 Sorbitan sesquioleate 0.8 Tocopherol o, i Preservative O/l Distilled water 39.6 Triethanolamine 0.7 1.3-butanediol 5.0 Fragrance 0.4 Example 2 Cold cream beeswax 5.0 Stearic acid 2.0 Cholesterol 5.0 Synthetic wax 2.0 Hydrogenated purified liquid lanolin 1.0 Purified liquid lanolin 5.0 Instearyl impalmitate 10.0 Squalane 27.0 Isooctyl triglyceride 3.0 Sodium polyoxyethylene α-lylauryl ether phosphate 3.3 Glyceryl monostearate 1.7 Preservative 0.2 Borax 0.4 1.3-Butanediol 3. 5 Distilled water 30.5 Flavor 0.4 Example 3 Emulsion beeswax 3.0 Purified liquid lanolin 4.0 Cholesterol 0.3 Behenic acid 0.4 Cholesteryl stearate 0.6 Pyridoxine dipalmitate 0.3 Propylene glycol Monostearate 1.5) Monostearic acid 1.0 Polyoxyethylene (e) behenyl alcohol 1.7 Preservative 0
．． 2 75-methylbronoquinone diol 0.51.3-butanediol 5.5 Distilled water 80.7 Fragrance 0.3 Example 4 Skin lotion ethanol 13. .

1.3-Butanediol 5.0 Water-soluble allantoin 0.1 Citric acid 0.1 Sodium citrate 0.1 Fragrance 0.1 Preservative 0.2 Distilled water 78.6 Hydrogenated purified liquid lanolin 2.0 Inoctyl Acid triglyceride 0.8 Example 57.
Surge oil in octylate tricrycerite 20.0 Sheathed liquid lanolin 20.0 Cholesterol S, O squalane 17.5 Instearyl isopalmitate 27.0 Cetyl isooctanoate 100 Preservatives 0.1 Pyridoxine dioct/ate 0. 3 Fragrance 0.1 Example 6 Hair Cream Ethanol 4.5 i,3-butanediol 5.1 Triethanolamine 0.3 Ultraviolet absorber 0 Preservative 02 Xanthan gum 01 Squalane 25.0 Microcrystalline wax 2. 0 Dimethylpolysiloxane 5.0 Rubitan monostearate 0.7 Polyoxyethylene(e)sorbitan monostearate 3.0 Sorbitan sesquistearate 1.5 Carbodivinyl polymer 〇, J Quince seed gum 0.1 Purified liquid lanolin 1.5 Cholestanol 0.5 Distilled water 50.0 Fragrance o2 Tocopherol 0.1 Patent applicant POLA CHEMICAL INDUSTRIES, INC.

Claims (1)

[Claims] l) A cosmetic containing purified liquid lanolin and/or hydrogenated purified liquid lanolin with an ester component content of 90% or more.