JPS5967966A - Infusion liquid filter - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

[Detailed Description of the Invention] ■ Background of the Invention (Technical Field) The present invention provides a filter for removing foreign substances and bacteria from infusions, etc.
In particular, it relates to the structure of the air vent section of this filter.

(Prior Art and its Problems) Currently, many filters of this type have been developed and are in use. The problems that have been pointed out will be explained below using typical examples.

(A) First example (see FIG. 1) As can be seen from the plan view of FIG. 1a and the side view of FIG. 1b, liquid enters from the connector 1 and flows through the hydrophilic filter 2 in the direction of the tube 3.

On the other hand, the mixed air is exhausted from the hydrophobic filter 4. The hydrophobic filter is made of Teflon and is adhered to the inner surface of the housing, with the adhesive surface being flat. Air is set to escape through four exhaust ports.

In such a configuration, not all of the air that has entered the filter will escape through the hydrophobic filter. Air bubbles that are deflected and flow onto the hydrophilic filter within the housing create a put zone on the hydrophilic filter, reducing the filtration area and reducing filtration efficiency. In order to remove the air bubbles that had entered, it was necessary to tilt the filter set and let them escape through the -C vent. Furthermore, since the hydrophobic filter is bonded to a flat surface, only the four exhaust ports are effective for air release, making it difficult for air to escape.

(B) Second example (see Figure 2) As can be seen from the plan view in Figure 2a and the cross-sectional view in Figure 2b, a hydrophobic filter 12/1 with a hydrophilic filter 1'1 in between. It is placed after ll rice iT. The liquid enters through the inlet 13, passes through the bottom surfaces of both filters, permeates into the hydrophilic filter 11, and exits through the outlet 14.
The mixed air passes through a hydrophobic filter 12 and exits from an exhaust port 15. Hydrophilic filter 11
and a support 16 from above and below for both the hydrophobic filter 12 and the hydrophobic filter 12.
The exhaust ports 15 are provided one for each section of the hydrophobic filter.

Hydrophobic filters are made of a laminate of Teflon and non-woven fabric.

The problem with this configuration is that air is difficult to escape and the shape becomes large.

(C) Third example (see Figure 3) In the configuration shown in Figure 3, the liquid that enters from the inlet 21 penetrates the hydrophilic filter 22 wrapped around the side of the cylinder inside the housing, passes through the groove 23 Exit through the exit. The mixed air passes through a hydrophobic filter 25 that is placed on the bottom of the cylinder near the inlet 21, passes through the hollow cylinder, and exits through the exhaust port 26.

There is no support for the hydrophobic filter 25 either inside or outside. Teflon is used as the hydrophobic filter 25.

A problem that has been pointed out with such a configuration is that not all of the air that has entered the housing escapes through the hydrophobic filter, and may deviate to the side and remain on the hydrophilic filter within the housing.

(D) Fourth example (see Figure 4) The plan view in Figure 4a, the sectional view in Figure 4b, and the fourth example
As can be seen from the cross-sectional view of the umbrella-shaped valve in FIG. The liquid that entered from the inlet 36 passes through the hydrophilic filter 37 and exits from the outlet 38, but the mixed air passes through the hydrophobic vent filter 39, pushes up the umbrella part 35 of the umbrella valve, and is discharged from the exhaust port 34. . The outside air does not enter the interior, and an automatic exhaust control means is provided.
is made of a laminate of Teflon and polyester non-woven fabric, and is heat-sealed to the inner surface of the housing. Details are described in Japanese Patent Publication No. 54-85478.

The problem with this configuration is that not all of the air that has entered the housing escapes through the hydrophobic filter, and may deviate to the side and remain in the hydrophilic filter 5 inside the housing.

■ Purpose of the Invention The purpose of the present invention is to provide an infusion filter with a simple structure that makes it possible to completely remove air mixed in infusions, etc., which was impossible with conventional filters of the same type. .

111 Specific Structure of the Invention The present invention consists of a case housing and a lid housing, and an infusion discharge port is provided on the side surface of the case housing to communicate the inside and outside, and the inside of the case housing A discharge passage communicating with the infusion discharge boat is provided on the bottom surface, a protrusion forming this discharge passage is used as a filter support, and the infusion discharge boat and the lid housing side are mounted on the filter support. A hydrophilic filter is provided so as to separate the lid body and the housing, and the air vent portion is provided with an air vent portion projecting outward, and an air vent port covered with a hydrophobic filter is provided within the air vent portion, and the air vent portion An infusion inlet is provided that communicates the inside and outside of the infusion, and a wall is provided in front of the infusion in the infusion direction, and air bubbles mixed in the infusion collide with this wall and are discharged to the outside through the hydrophobic filter of the air vent. The present invention provides an infusion liquid filter device configured to perform the following steps. Although the wall surface may be formed of a hydrophobic filter, it is preferable that the wall surface is an inner wall surface of the air venting section, and that the infusion inlet is provided on the side surface of the air venting section. It is preferable that the angle between the infusion inflow direction and the wall surface be 90° to 120°, and that the upper end surface of the cylindrical air vent be the air vent. It is configured to be placed below the hydrophobic filter in the mouth, at a position that is 1/3 of the distance from the infusion inflow side end of the hydrophobic filter to the infusion inflow direction of the hydrophobic filter, and furthermore, the shortest distance between the infusion inlet and the hydrophobic filter is It is preferable that the membrane area of the hydrophobic filter is 5718 or less, and the membrane area of the hydrophobic filter is 2 to Q, 5 crl.

Hereinafter, the infusion filter of the present invention will be described in detail with reference to preferred embodiments shown in the accompanying drawings.

FIG. 5 is a side view of the infusion device 50 for the first patient, FIG. 6 is a side view as seen from the right side of FIG. 5, and FIG. 7 is a plan view thereof. As can be seen from these drawings, the infusion device 50 of the present invention consists of a casing housing song 51 and a lid body l/ku song 52 that are attached to each other. A channel 54 communicating with the infusion discharge port 53 is provided on the inner bottom surface of the housing 51, and the protrusion 55 forming the discharge channel 54 is used as a filter support (see FIG. 6). A hydrophilic filter 56 is provided to separate this support upper discharge port 53 from the lid side.

The lid housing 52 has an air vent portion 56 projecting outward.
will be established. An infusion inlet 58 is formed on the side surface of the air vent portion 57, and an air vent 59 is formed on the upper end surface.
A cross-shaped support 60 is formed at the bottom of the support 60, and a hydrophobic filter 61 is attached to the air vent 59 by gluing, welding, etc. so as to be supported by this (see FIGS. 8 and 9). .

In use, the infusion filter of the present invention has a luer connector 62 connected to an infusion bag as shown in FIG.
is inserted into the infusion inlet 58, the infusion is made to collide with the wall surface 63 of the air vent part 57, and the infusion is passed through the hydrophilic filter 56.
After that, the mixed air is discharged from the hydrophobic filter 61. Therefore, there are conditions suitable for improving G air bleed performance between the elements of the related air bleed portions, which will be explained with reference to FIG. 10.

A hydrophobic filter 61 is placed on the side of the infusion inlet 64.
The infusion inlet 64 should be located between two-thirds of the end of the hydrophobic filter 61 (diameter D) (
In other words, it is preferable to wake up by 1 degree (d≦2/3D). The reason for this is that the entire surface of the hydrophobic filter is effectively involved in air release.

In addition, the angle α (i90° to 12
It is preferable to set it to 0°. The reason for this is that if the angle is less than 90 degrees, the flow of the liquid may be obstructed, and if it is greater than 120 degrees, the air may follow the flow of the liquid, pass through the air vent, and flow into the filtration section. . Infusion inlet 64
The shortest distance form between the word and the hydrophobic filter 61 is preferably five words or less. The reason is that the mixed air can be removed more quickly than with a hydrophobic filter. Further, the effective membrane area of the hydrophobic filter 61 is preferably 0.2 to 0.6 crl.

The reason for this is that if the area is 0.2 cd or less, it is insufficient for air to escape, and even if the area is 0.6 cd or more, the effect will not change. Methacrylate butadiene styrene/
) A resin is preferable, and the hydrophobic filter 61 is preferably made of Boertex or the like, and the hydrophilic filter 56 is preferably made of acid 1v cellulose or the like.

(2) Specific Functions of the Invention Next, the functions of the infusion filter of the present invention will be briefly explained.

As shown in FIG. 10, the infusion that flows into the Luer connector 62 connected to the infusion bag at a predetermined distance from the infusion inlet 58 collides with the wall 63 facing the air vent 570, Due to the inclination angle α, the liquid flows toward the hydrophilic filter 56, and the air that has entered is separated from the liquid flow due to the above-mentioned collision and is diverted toward the hydrophobic filter 61. Since the air that has been mixed in with the infusion liquid is no longer diverted toward the hydrophobic filter 61 and attached thereto as air bubbles, it is almost completely discharged from the hydrophobic filter 61.

In the infusion filter of the present invention, when the hydrophilic filter 56 is tied, air will not pass through the hydrophilic filter 56 at a pressure of 3.911 p/- or less, and 2.8 KP/- It is constructed so that the infusion solution will not penetrate into the hydrophobic filter 61 at the pressure below.

In order to confirm the effectiveness of the infusion filter of the present invention, the following tests were conducted using Bove Sample 1.11.1. The results are shown in Table 1 t0 (1) Structure of the infusion filter of the present invention...Sample I (a) Hydrophobic filter material: laminate thickness of porous Teflon and polyderobylene filtrate = 185-285μ Effective membrane surface M: 0.4cJ (b) Dimensions α = 111°, β = 111°, g = l l mx.

d-4/7D, (2) The first example shown in No. 11'4... Sample ■ Effective membrane area of hydrophobic filter + 0.45 c-J + 31
g The third example shown in Figure 3 Sample ■ Effective membrane area of hydrophobic filter: 0.45 cJ (・υ Test method Physiological saline (0.9% NaC6 solution) was poured as an infusion solution at different flow rates. We investigated the state of air removal from the hydrophobic filter when 20 mm of air was injected at a time.The test was conducted in a vertical position with the filter facing the liquid inlet, and in a vertical position with the filter facing the liquid inlet. The test was carried out both in the horizontal position and in the horizontal position.

(5) Results Generally, when the infusion flow rate is low, it becomes difficult for air to escape, but in the product of the present invention (sample I), air escape was good in all cases. However, in sample ■, the flow rate was 6 Or,
77! There were cases where the air could not be released when around / hr. Furthermore, sample 11 had poor air release. In the case of sample 11, there seems to be a problem with the supporting shape of the hydrophobic filter, but in the case of sample 111, there is no support and the effective area is large, so the effectiveness of the product of the present invention is clear.

(2) Specific Effects of the Invention As is clear from the above, the infusion filter of the present invention provides many advantages over conventional ones, as described below.

(1) In the present invention, an air bleed part is provided as a protruding part of the lid housing, and the infusion liquid is made to collide with the wall surface of the air bleed part, and the air is bleed using a hydrophobic filter above the collision part. It is based on the idea that there is no
Entrained air can be almost completely eliminated, and stable filtration efficiency can be ensured even if air accumulates on the hydrophilic filter and reduces the effective membrane area of the filter.

(2) The wall structure of the air bleed section is such that collided infusion liquid is sent to the hydrophilic filter, and mixed air is separated and sent to the hydrophobic filter, improving air bleed performance.

13) It achieves higher air removal performance with a smaller effective membrane area than that of conventional hydrophobic filters, so it can be made smaller.

(4) The structure of the vent part is very simple, easy to assemble and maintain, and since the hydrophobic filter is provided only in the upper part of the air vent part, it has a small area and is inexpensive.

(5) The angle between the infusion inflow direction and the infusion collision wall is 90
If the angle is between 120° and 120°, the best air release properties will be achieved.

(6) The infusion inlet is located below the hydrophobic filter of the air vent port, and has a distance from the infusion inflow side end of the hydrophobic filter to the infusion inflow direction of the hydrophobic filter;
If the hydrophobic filter is configured to be located up to this position, the entire surface of the hydrophobic filter can be used for air bleed.

(7) By setting the shortest distance between the infusion inlet and the hydrophobic filter to less than 5 mm, incoming air can be removed more quickly than with the hydrophobic filter.

(8) Effective membrane area of hydrophobic filter is 0.2 to 0.6
-, sufficient air bleed performance will be exhibited.

[Brief explanation of drawings]

1a and 1b are a plan view and a side view, respectively, of a first example of a conventional infusion filter; FIGS. 2a and 2b are a plan view and a sectional view, respectively, of a second example of a conventional infusion filter; FIG. 3 is a partially sectional side view of a third example of a conventional infusion filter, and FIGS. 4a, 4b, and 4C are a plan view, a sectional view, and a partial view, respectively, of a fourth example of a conventional infusion filter. , FIG. 5 is a side view of the infusion filter of the present invention, FIG. 6 is a right side view of FIG. 5, FIG. 7 is a plan view of the same, and FIG. FIG. 9 is a plan view, FIG. 9 is a cross-sectional view of the vent portion, and FIG. 10 is a cross-sectional view of the vent portion during use. Explanation of symbols 1... Connector, 2, 11, 22. 37... Hydrophilic filter, 3... Tube, 4.12.25.39.
...Hydrophobic filter, 13,21.36...Inlet,
14.24.38...exit, 15,26,34...
Exhaust port, 16... Support, 23... Groove, 31...
Hole, 32...Umbrella-shaped well, 33...Root, 35...Umbrella part, 50...Filter of the present invention, 51...Housing No. 1 Uzing, 52... Lid No. 1 Ukung, 53... Infusion outflow boat, 54... Channel, 55... Projection, 56...
・Hydrophilic filter, 57...Air vent part, 58・-
・Infusion inlet, 59...Air vent, 60...Support, 61...Hydrophobic filter, 62...Luer connector, 63...Infusion liquid collision wall surface, 64...4 Liquid inflow Department Patent Applicant Terumo Co., Ltd. Representative Patent Attorney Nozomu Watari 2,? ,゛ha′,j
' 5061 First mouth 61 1

Claims (1)

[Claims] (1) Consisting of a case housing and a lid housing, an infusion discharge port that communicates the inside and outside is provided on the side surface of the case housing, and an infusion discharge port that communicates with the infusion solution discharge port is provided on the inner bottom surface of the case housing. Provide a drainage flow path that leads to
The protrusion forming this discharge flow path is used as a filter support, and a hydrophilic filter is provided on the filter support so as to separate the infusion discharge port from the lid housing side. An air bleed part protruding from the air bleed part and an air bleed port covered with a hydrophobic filter are provided in the air bleed part, and an infusion inlet is provided that communicates the inside and outside of the air bleed part, and the infusion in the infusion inlet is provided. An infusion filter characterized in that a wall surface is provided in the front in the inflow direction, and air bubbles mixed in the infusion collide with this wall surface and are discharged to the outside through a hydrophobic filter of the air vent port. 12) The infusion filter according to claim 1, wherein the wall surface is dust-free on the inner wall surface of the air venting part, and an infusion inlet is provided on the side surface of the air venting part. The angle with the wall is 900~
1200. The infusion filter according to claim 1 or 2, which is 1200. +41 The infusion filter according to claim 2 or 3, wherein the upper end surface of the cylindrical air bleed portion serves as an air bleed port. 15) The infusion inlet is located below the hydrophobic filter of the air vent, at the 30th position i of the infusion inflow direction distance of the hydrophobic filter from the infusion inflow side end of the hydrophobic filter.
5. The infusion filter according to claim 4, wherein the infusion filter is configured to be 14 by t. 16) The infusion filter according to any one of claims 1 to 5, wherein the shortest distance between the infusion inlet and the hydrophobic filter is five sides. (7) The effective membrane area of the hydrophobic filter is 0.2 to C), 6 cmJ'? 1
The infusion filter according to any one of claims 1 to 6.