JPS5933018B2 - Method for manufacturing microcapsules of high melting point substances and its manufacturing equipment - Google Patents
Method for manufacturing microcapsules of high melting point substances and its manufacturing equipmentInfo
- Publication number
- JPS5933018B2 JPS5933018B2 JP3356080A JP3356080A JPS5933018B2 JP S5933018 B2 JPS5933018 B2 JP S5933018B2 JP 3356080 A JP3356080 A JP 3356080A JP 3356080 A JP3356080 A JP 3356080A JP S5933018 B2 JPS5933018 B2 JP S5933018B2
- Authority
- JP
- Japan
- Prior art keywords
- cooling liquid
- melting point
- manufacturing
- refluxing
- nozzle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nozzles (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Description
【発明の詳細な説明】
本発明は高融点物質のマイクロカプセル製造方法及びそ
の装置に関するものである。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a method and apparatus for producing microcapsules of high melting point substances.
従来のカプセル製造装置では高融点物質の場合、粒径を
２ｍｍΦ以下にすることは困難であつた。In the case of high melting point substances, it has been difficult to reduce the particle size to 2 mmΦ or less using conventional capsule manufacturing equipment.
その理由は高融点物質のジェットが急速に冷却されるた
め、ジェットの切れが悪くなつて均一な微小カプセルが
得られないからである。それ故、ジェットの冷却時間が
問題であつてこれを自由に調節できれば高融点物質のカ
プセル化は可能となることが判明した。本発明の目的と
するところは、この高融点物質のマイクロカプセルを得
る方法及びその製造装置を提供するにある。The reason for this is that the jet of high melting point material is rapidly cooled, making it difficult to cut the jet and making it impossible to obtain uniform microcapsules. Therefore, it has been found that the jet cooling time is a problem and that if it can be freely adjusted, it becomes possible to encapsulate high melting point substances. An object of the present invention is to provide a method for obtaining microcapsules of this high melting point substance and an apparatus for producing the same.
本発明に係る製造装置を用（・ると高融点物質のジェッ
トが急速に冷却されることがなくなるので、ジェットが
切れる以前に固化する現象が完全に改善された。By using the manufacturing apparatus according to the present invention, the jet of high melting point material is no longer cooled rapidly, so the phenomenon of solidification before the jet is cut off has been completely improved.
本発明は微小のカプセルだけでなく粒径のや大きいカプ
セルの製造にも充分に応用できるものである。The present invention can be fully applied to the production of not only microcapsules but also capsules with larger particle sizes.
又本発明は従来のマイクロカプセル製造法で得られるカ
プセルのもつ欠点であるところの皮膜の厚いこと、皮膜
が水に溶けないこと又方法として有機溶媒を使用しなけ
れば出来ないと（・う点更に食品分野への応用の困難性
と（・うような諸点を一挙に改善することに大きな役割
りを果し得たものである。本発明の要旨は特許請求の範
囲に記載せる如く、還流する冷却液中に二重ノズルの先
端よりカプセル充填物質、及び被膜物質を押し出して継
目なしカプセルを製造する場合において、二重ノズルか
・ ら押し出されるカプセル充填物質、及び被膜物質の
ジェット流が還流冷却液ａ中に押し出される以前に、該
還流冷却液ａよりも高（・温度に設定された他の冷却液
ｂを該ジニット流の周囲に接触せしめ、さらにこれらの
カプセル充填物質、被膜物質及び冷却液ｂを一体となつ
たジニット流１０として還流冷却液ａ中に押し出し成形
することを特徴としており、またその装置は、従来の還
流する冷却液中に二重ノズルの先端よりカプセル充填物
質、及び被膜物質を押し出して継目なしカプセルを製造
する装置にお〜・て、還流冷却液の還流パイプより分岐
せしめたもう一つのパイプの途上に、冷却液ｂを貯蔵す
るタンク３を設けると共に、該タンク３から定量ポンプ
６を介して延びるパイプ１９の先端部を三重ノズル７に
おける最も外側のノズルJヨ黷Rに開口せしめて構成され
るものである。In addition, the present invention overcomes the disadvantages of capsules obtained by conventional microcapsule manufacturing methods, such as the thickness of the film and the insolubility of the film in water, and the fact that the process requires the use of an organic solvent. Furthermore, it played a major role in all at once improving the difficulties of application to the food field. When manufacturing seamless capsules by extruding capsule filling material and coating material from the tip of a double nozzle into a cooling liquid, the jet stream of capsule filling material and coating material extruded from the double nozzle is refluxed. Before being forced into the cooling liquid a, another cooling liquid B, set at a higher temperature than the refluxing liquid A, is brought into contact with the surroundings of the dinit stream, and the capsule filling material, coating material and The device is characterized by extrusion molding the coolant b as an integrated dinit stream 10 into the refluxing coolant a, and the apparatus is capable of injecting the capsule filling material into the refluxing coolant from the tip of a double nozzle into the conventional refluxing coolant. And in the apparatus for manufacturing seamless capsules by extruding the coating material, a tank 3 for storing the cooling liquid b is provided in the middle of another pipe branched from the reflux pipe for the reflux cooling liquid. It is constructed by opening the tip of a pipe 19 extending from the tank 3 via the metering pump 6 to the outermost nozzle J and R in the triple nozzle 7.
次に添付図面によつて、本発明に係る高融点物質のカプ
セル製造装置につき以下詳細に説明する。図にお（・て
１はカプセルの皮膜物質を入れるタンクで、ここから出
る液送パイプは、このタンク１より定量ポンプ４を介し
て図に示す三重ノズル７の中筒ノズルJヨ黷Pとなつてお
り、又２はカプセル充填物質を入れるタンクで、定量ポ
ンプ５を介して図に示す三重ノズル７の中心のノズルJ
ヨ黷Qを形成し又３は冷却液ｂを入れるタンクで、この
タンク３から出て℃・る液送パイプ１９は定量ポンプ６
を介して三重ノズル７の最外側のノズル７３内に開口せ
しめられている。そして、この三重ノズル７の先端部は
、冷却器８内に設けてある造粒筒９の頂部に向かつて下
向きに臨ましめてある。次にこの造粒筒９の底部は造粒
筒９内で球状となつたカプセルを搬出する回収管１１に
接続されており、その先端部は分離板１２を備えたセパ
レーター１３上に開口されて（・る。そしてセパレータ
ー１３の底部からは還流パイプ１４がのびて循環ポンプ
１５を経て熱交換器１７内に入り、この熱交換器１７に
接続されて℃・る冷却液送パイプ１８は、冷却器８の下
方に開口せしめられて℃・る。ここで本装置の特徴とす
る構成は、セパレーター１３の底部に接続される還流パ
イプ１４は循環ポンプ１５に至るべく分岐されたパイプ
を過ぎてその前方で１４−１と（・うパイプと定量ポン
プ１６を介して設定温度にした還流冷却液ｂを貯蔵する
ところのタンク３に接続されて（・る点である。次に上
記の如き構成からなる製造装置を用いて高融点物質のマ
イクロカプセルを製造する方法を１実施例で説明すると
本例においてはカプセル充填物質としてパームロウ（Ｍ
ｐ８６は）、カプセル皮膜物質としてゼラチン２０％、
精製水８０％の混合液又還流冷却液Ａ，ｂも共に流動パ
ラフインを使用した。常法に従い、従来の如きカプセル
製造の工程にお〜゛て、ノズルから押し出されるジニッ
ト流が還流冷却液ａ中に押し出される以前に還流冷却液
ａよりも高い温度に設定してお（・た還流冷却液ｂを充
填物質と皮膜物質のタンク１及び２に通じて（・るノズ
ルの周囲に流してジニットの流れと接触させ、カプセル
充填物質、被膜物質及び冷却液ｂを一体となつたジニッ
ト流１０として造粒筒９内に押し出すことによつて、バ
ームロウの如き高融点の物質も容易にマイクロカプセル
化することができる。Next, the apparatus for manufacturing capsules of high melting point substances according to the present invention will be explained in detail below with reference to the accompanying drawings. In the figure (1) is a tank that holds the capsule coating material, and the liquid feed pipe that comes out from this tank is connected to the middle cylinder nozzle J and P of the triple nozzle 7 shown in the figure via a metering pump 4. 2 is a tank containing the capsule filling material, which is passed through a metering pump 5 to the center nozzle J of the triple nozzle 7 shown in the figure.
3 is a tank in which the cooling liquid B is placed, and a liquid sending pipe 19 that comes out from this tank 3 is connected to a metering pump 6.
It is opened into the outermost nozzle 73 of the triple nozzle 7 through. The tip of this triple nozzle 7 faces downward toward the top of a granulating cylinder 9 provided in a cooler 8. Next, the bottom of this granulation cylinder 9 is connected to a collection pipe 11 for carrying out the spherical capsules inside the granulation cylinder 9, and the tip thereof is opened onto a separator 13 equipped with a separation plate 12. A reflux pipe 14 extends from the bottom of the separator 13, passes through a circulation pump 15, and enters the heat exchanger 17. The device is opened at the bottom of the vessel 8 at a temperature of 0.degree. 14-1 at the front and is connected to the tank 3 which stores the reflux coolant B at the set temperature via the pipe and the metering pump 16.Next, from the above configuration, In this example, a method for manufacturing microcapsules of a high-melting point substance using a manufacturing apparatus will be described. In this example, palm wax (M
p86), 20% gelatin as capsule coating material,
Liquid paraffin was used for both the 80% purified water mixture and the reflux cooling liquids A and b. According to a conventional method, in the conventional capsule manufacturing process, the temperature of the dinit stream extruded from the nozzle is set higher than that of the refluxing liquid A before it is extruded into the refluxing liquid A. The refluxing coolant b is passed through the tanks 1 and 2 of the fill material and the coating material (-) around the nozzle and in contact with the flow of dinit, so that the capsule fill material, the coating material and the coolant b are combined with the dinit. By extruding it into the granulation cylinder 9 as the stream 10, even substances with a high melting point such as berm wax can be easily microencapsulated.
高融点（ＭｐｌＯＯ℃）の油状物質のマイクロカプセル
化による利点を次に列挙する。The advantages of microencapsulating oily substances with high melting points (MplOO°C) are listed below.
（イ）１酸敗又は水分等の影響による劣化を防止できる
。(b) 1. Deterioration due to rancidity or the influence of moisture, etc. can be prevented.
２分割使用を容易にする。Facilitates two-part use.
３カプセルに携帯性をもたすことが可能となつた。It has become possible to bring portability to 3 capsules.
４包装充填の簡易化を計ることが可能である。4. It is possible to simplify packaging and filling.
以上の４点にお℃・て大きな利点効果が期待できる。（
ロ）このような利点を有する高融点物質のマイクロカプ
セルの製造は本装置によつて容易に可能となつた。We can expect great benefits from the above four points. (
(b) The production of microcapsules of high melting point substances having such advantages has become easily possible with this apparatus.
（ハ）本発明に係る方法で行うと核物質の冷却時間が延
長されジニットの切れが良くなり粒径の揃つた高融点物
質のマイクロカプセルが得られる。(c) When the method according to the present invention is carried out, the cooling time of the core material is extended, the dinit is cut easily, and microcapsules of high melting point material with uniform particle size can be obtained.
（ニ）三重ノズル方式なので、ノズルが冷却されすぎて
核物質がノズルの先端につまると℃・うような現象が全
くなくなつた。(d) Because it uses a triple nozzle system, there is no longer any phenomenon that occurs when the nozzle is cooled too much and nuclear material gets stuck at the tip of the nozzle.
図に示すものは本発明に係る高融点物質のマイクロカプ
セル化の製造装置の簡略化した説明図である。
１・・・・・・皮膜物質を入れるタンク、２・・・・・
・カプセル充填物質を入れるタンク、３・・・・・・第
２冷却液を入れるタンク、４，５，６・・・・・・定量
ポンプ、７・・・・・・同心三重ノズル、８・・・・・
・冷却器、９・・・・・・造粒筒、１０・・・・・・ジ
ニット流、１１・・・・・・カプセル回収管、１２・・
・・・・セパレーター １３・・・・・・冷却液回収器
、１４・・・・・・還流パイプ、１５・・−・・・循環
ポンプ、１６・・・・・・定量ポンプ、１７・・・・・
・熱交換器、１８，１９・・・・・・冷却液送パイプ、
ａ・・・・・・冷却液、ｂ・・・・・・温度を設定せる
冷却液。What is shown in the figure is a simplified explanatory diagram of a manufacturing apparatus for microencapsulating a high melting point substance according to the present invention. 1...Tank for containing the film material, 2...
・Tank for storing capsule filling material, 3...tank for holding second cooling liquid, 4, 5, 6...metering pump, 7...concentric triple nozzle, 8.・・・・・・
・Cooler, 9... Granulation cylinder, 10... Dinit flow, 11... Capsule collection pipe, 12...
... Separator 13 ... Cooling liquid collector, 14 ... Reflux pipe, 15 ... Circulation pump, 16 ... Metering pump, 17 ... ...
・Heat exchanger, 18, 19... Coolant sending pipe,
a...Cooling liquid, b...Cooling liquid whose temperature can be set.
Claims (1)
充填物質、及び被膜物質を押し出して継目なしカプセル
を製造する方法において、二重ノズルから押し出される
カプセル充填物質、及び被膜物質のジェット流が還流冷
却液ａ中に押し出される以前に、該還流冷却液ａよりも
高い温度に設定された他の冷却液ｂを該ジェット流の周
囲に接触せしめ、さらにこれらのカプセル充填物質、被
膜物質及び冷却液ｂを一体となつたジェット流１０とし
て還流冷却液ａ中に押し出し成形することを特徴とする
高融点物質のマイクロカプセル製造方法。 ２ 還流する冷却液中に二重ノズルの先端よりカプセル
充填物質、及び被膜物質を押し出して継目なしカプセル
を製造する装置において、還流冷却液ａの還流パイプよ
り分岐せしめたパイプの途上に冷却液ｂを貯蔵するタン
ク３を設けると共に、該タンク３から定量ポンプ６を介
して延びるパイプ１９の先端部が、二重ノズルの更に外
側を取り囲むノズル７−３に開口せしめられていること
を特徴とする高融点物質のマイクロカプセル製造装置。[Claims] 1. A method for manufacturing a seamless capsule by extruding a capsule filling material and a coating material from the tip of a double nozzle into a refluxing coolant, the capsule filling material and coating material being extruded from a double nozzle. Before the jet stream of material is forced into the reflux cooling liquid a, another cooling liquid b set at a higher temperature than the reflux cooling liquid a is brought into contact around the jet stream, and these capsule filling materials are A method for producing microcapsules of a high-melting point substance, which comprises extruding a coating material and a cooling liquid b into an integrated jet stream 10 into a refluxing cooling liquid a. 2. In an apparatus for manufacturing seamless capsules by extruding capsule filling material and coating material from the tip of a double nozzle into a refluxing coolant, cooling liquid B is placed in the middle of a pipe branched from a reflux pipe for refluxing coolant A. The present invention is characterized in that a tank 3 is provided for storing the liquid, and the tip of a pipe 19 extending from the tank 3 via a metering pump 6 is opened to a nozzle 7-3 that surrounds the further outside of the double nozzle. Microcapsule production equipment for high melting point substances.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3356080A JPS5933018B2 (en) | 1980-03-17 | 1980-03-17 | Method for manufacturing microcapsules of high melting point substances and its manufacturing equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3356080A JPS5933018B2 (en) | 1980-03-17 | 1980-03-17 | Method for manufacturing microcapsules of high melting point substances and its manufacturing equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56130219A JPS56130219A (en) | 1981-10-13 |
| JPS5933018B2 true JPS5933018B2 (en) | 1984-08-13 |
Family
ID=12389928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3356080A Expired JPS5933018B2 (en) | 1980-03-17 | 1980-03-17 | Method for manufacturing microcapsules of high melting point substances and its manufacturing equipment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5933018B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2018190432A1 (en) * | 2017-04-14 | 2020-05-14 | 富士カプセル株式会社 | Method of manufacturing soft capsule aggregate and soft capsule aggregate |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1033128T2 (en) * | 1993-09-28 | 2012-02-29 | Scherer Gmbh R P | Soft gelatin capsule manufacture |
| US9039273B2 (en) * | 2005-03-04 | 2015-05-26 | President And Fellows Of Harvard College | Method and apparatus for forming multiple emulsions |
| BR112012004719A2 (en) | 2009-09-02 | 2016-04-05 | Harvard College | multiple emulsions created by blasting and other techniques |
| EP2714254B1 (en) | 2011-05-23 | 2017-09-06 | President and Fellows of Harvard College | Control of emulsions, including multiple emulsions |
| JP2014522718A (en) | 2011-07-06 | 2014-09-08 | プレジデント アンド フェローズ オブ ハーバード カレッジ | Multiphase emulsion and method for forming multiphase emulsion |
| JP6091679B1 (en) * | 2016-03-29 | 2017-03-08 | 株式会社松風 | Droplet generator |
-
1980
- 1980-03-17 JP JP3356080A patent/JPS5933018B2/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2018190432A1 (en) * | 2017-04-14 | 2020-05-14 | 富士カプセル株式会社 | Method of manufacturing soft capsule aggregate and soft capsule aggregate |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56130219A (en) | 1981-10-13 |
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