JPS5932861A - Liquid chromatographic mass analyzer - Google Patents

Abstract

PURPOSE:To achieve a smooth and stable atomization even in a limited flow rate by applying a strong electric field near an emission nozzle, which has the direction the same as the jetting direction of an effluent. CONSTITUTION:An effluent fed through a feed tube 12 is injected and atomized into a low pressure glass tube 1 from an emission nozzle 2. At the same time, a spray gas is injected in the direction of the emission nozzle 4 from the perimeter of the nozzle 2 through an air blow tube 13 to promote the atomization. A circular electrode 15 is arranged near the emission nozzle 4. When a negative high voltage is applied from a power source 16 to provide a strong electric field near the nozzle 2, a solvent in the effluent appearing at the nozzle tip is polarized to be charged and so attracted by the strong electric field to jet out of the nozzle 2 with a force thereby enabling an extremely smooth atomization even in a limited flow rate.

Description

[Detailed description of the invention] This light is an invention] J! 1 - Relating to a device that combines a graph and a mass spectrometer, particularly a device that atomizes and introduces the effluent of a liquid column into a mass spectrometer.

To separate a multi-component mixed sample -C analysis 7;
7 tograno is a useful device, especially if it is coupled with a mass spectrometer (a detection means), it is possible to obtain information about the molecular structure of the molecule -m-t'1. Current r1
In addition, gask [l madograph and j'4
A device that combines a mass spectrometer and a mass spectrometer requires a variety of personnel (1-1) to introduce the liquid into the mass spectrometer. Attempt+
It is at the stage of 1C.

Figure 1 is a schematic diagram of the -7'J formula of Deno.) et al.
In the figure, 1 is a glass tube C7t6 which is internally aerated by a vacuum pump. A conductive I11 nozzle 2 is inserted into the lath tube, and a liquid 1 as shown in the figure is inserted.
The effluent of 1 matograno l) + i et al.
l! Ii 3, 3 is a heater for heating the tip part 1111 to prevent supercooling N1 and dyeing.

Output nozzle 2 /, +": T > The effluent jetted into the low-pressure glass tube (61, becomes a mist, further vaporizes, and is placed in the *i1 part of the glass tube 1 so that the nozzle 21 is facing towards the rear.
9? The flow path 5) 41' is introduced into the inlet side nozzle 1.
The first C (A power supply) 1.1 is returned to the ionization chamber 7 in the first block 0 (to be ionized), and the second one is ionized.

A conventional example with such a configuration (1111) is the case where the inductance applied to the nozzle 2 is adjusted to the flow rate of the effluent, and when the flow rate is high, it is necessary to increase the inductance, and when the flow rate h1 is small, it is necessary to decrease the inductance. However, if the inductance is reduced quickly, clogging, etc., and atomization will not occur stably, and a good IIT IIFfl will be 1!7. 1 Not tl-Kadoi: Two (I,:.

The present invention has been made in view of the second principle, and is
t＞J Applying a strong electric current W having the same direction as the ejecting direction of the effluent to the tip of the nozzle will result in stable atomization from c′ if the inductance is small (). 1-1 to capture and provide a liquid container (17)
I'm on target. An embodiment of the present invention is hereinafter described in attached drawing F-1 (J-3).

Figure 2 is a cross-sectional view of the configuration of Emei Ki's embodiment (the same components as in Figure '1' are numbered the same). 5 Nos ♀ to 1 (Ma1.t
(I was taken to book 0 and 11, and inside the house (yo)]
1-Tally pump 1) is used to vacuum the insulation guide C. Inside it (,,L), the IJJ nozzle 21\liquid feed pipe 12 carrying the effluent and the air feed pipe 1ζ are inserted. 2] Juukan Suzou Donatsu'Ca-3, Pal 1"l/1 and air pipe 1
The spray force of helium etc. is +A through 3. In the vicinity of the Okawa nozzle 4, a circular mold 44i 15 is arranged so as to surround the nozzle (1). A Tari,
This point (2) The human structure of the present invention 4: 1h characteristics (b. 1
7, move the insulating force id 11 in the direction of the arrow jj, and adjust the distance between the output nozzle and the large sword nozzle.
(be.

In the configuration as described above, the sending method '12 is fl 1
．． , - The effluent sent through the outlet nozzle 27] I Lr Low Moon Sword - IlO is discharged into the Nos tube 1 and is atomized, but the same +1
．． 'i l-: The atomized gas flows from around the nozzle 2 through the air supply pipe '131 to 80.1. Nozzle 'I (7) /'J
When the atomization is ejected in the direction of
if 'The jetting and atomization of the effluent from the J nozzle 2 is directed to the jj direction of the input nozzle 4 () (i)
(l) gills 1.

(2ro(・、Liquid 1-1-1 to Grano C The solvent used usually has a frame 171. Therefore, near the nozzle 2 (mark the power with a strong electric W 11++). However, from the nozzle tip to the face The solvent in the effluent (, 1) is pulled by the strong electric field (nozzle 21) and jumps out. Therefore, this force causes the atomization to move in the direction of (jj), and compared to the case where no electric field is applied, the atomization progresses at Cb when the flow rate is small. (smoothly (5 to be done)
'Niru.

Inventive stone experiment C, the distance between nozzles is 5 to 7 Ill
m(, when applying an electric current of around 21 < \/ to J4i i 5, a flow of 1 ()/l Ω5, ·' minutes...c is also extremely fine - C fine mist stably flows 1!1, The flow rate of 11 or more ("t)-1 can be used for public use (approval U-ki/).

In this way, there was a fine frost, and the vaporized effluent was further vaporized (mann mist). and solvents tend to preferentially remove relatively small solutes with relatively high molecular weights. Cotton cotton state 4 - q.1 people are introduced into the use nozzle 4 - Introduced into the ionization chamber 7 (ionized).

As described in Section 5 below, in the present invention, J is +lj Q=1
By applying a strong electric field with the same direction as the ejecting direction of the effluent to the side of the nozzle, stable atomization can be achieved in the nozzle with a small flow rate. 1.
1:,7 A spindle-shaped υ1 quantity analyzer is realized.

It should be noted that the details are limited to the above-mentioned embodiments (numerous modifications are possible without *).

For example, set the circular electrode 153 (instead of J), change the tip of the Okawa nozzle 4 to an electrode structure, and apply a convex moon to the NJ of the Degawa nozzle 2. II I
Go;ii6? r: You can "turn the world to 1" [

[Brief explanation of drawings]

Figure 1 is a side view showing the configuration of a conventional device, and Figure 2 is a side view showing the configuration of an embodiment of the present invention.
0, 1 Nigasis tube, 2: 1 nozzle, 4: Large sword nozzle, 7: Ionization chamber, 10: +, +- tally pump, 11: Insulation guide,
12: Liquid feeding pipe, 15: Circular 71 (pole, 'IG: Power supply. Special 1 Applicant 11 Hon Electronics Co., Ltd. Representative Ministry Ito-jin

Claims (1)

[Claims] 1. A low-pressure chamber that is evacuated by a vacuum pump; −1 The corresponding output in the room 0 = 1
The flow path connecting the inlet nozzle to be placed and the ion source of the analyzer F1 (where the input nozzle is) Liquid liquid [-171-grano material analysis device] characterized by applying a strong electric field with ejection direction yj. 2. Arranged around the metallic output nozzle and the input nozzle. The liquid chroma 1 to graph mass spectrometer according to claim 1, wherein the strong electric field is reduced by applying a high voltage between the electrode and the counter electrode.