JPS5925446Y2 - Solvent deaerator - Google Patents

Description

[Detailed Description of the Invention] This invention relates to a solvent degassing device that degasses a solvent by sucking gas into the solvent.

Conventionally, a gas flow rate regulating means is connected to a degassing gas supply source, a plurality of degassing gas passages are connected to the gas flow rate regulating means via a branching means, and a filter means is provided at each tip of the degassing gas passage. A solvent degassing device is known.

With this device, for example, a degassing gas such as helium is fed into each mobile phase solvent of a high-performance liquid chromatograph as fine bubbles to expel air dissolved in the solvent.

However, the above conventional device has the following problems.

First, it is necessary to perform deaeration by adjusting the flow rate of the degassing gas according to the type and amount of solvent, and after the degassing is completed, the flow rate must be adjusted again to maintain the degassing state. It is necessary to continue sending deaerated gas at a certain flow rate, and as a result, it is necessary to adjust the flow rate twice.

Second, the resistance value of each degassing gas flow path differs due to differences in the liquid pressure and viscosity of the solvent applied to the filter means attached to the tips of the multiple degassing gas flow paths. This is because the gas flow rate in the gas flow path becomes unbalanced and unstable.

In order to prevent this, each degassing gas flow path may be provided with a flow rate adjusting means individually, but it takes time and effort to adjust each of them.

This invention was made with the aim of solving the problems mentioned above.

This invention will be explained in detail below based on the embodiment shown in the drawings.

Note that this invention is not limited to this.

1 shown in FIG. 1 is an embodiment of the solvent degassing device of this invention.

This device 1 connects a bellows valve 3 to a helium gas cylinder 2, connects a parallel gas flow path 4 to the bellows valve 3, and connects three helium gas flow paths 10 to the parallel gas flow path 4 via a branch pipe 9. , 11.degree. 12 are connected to each other, and sintered metal filters 13, 14.15 having a nominal roughness of about 2 .mu.m are attached to the tips of each helium gas flow path 10, 11.12.

The parallel gas flow path 4 consists of a main gas flow path 4a in which only a solenoid valve 5 is interposed, and a small flow rate gas flow path 4b in which a solenoid valve 6 and a resistance pipe 7 are interposed.

The flow rate ratio of these channels 4 a and 4 b is preferably 5:
The ratio is about 1 to 10:1.

The electromagnetic valves 5 and 6 are controlled by a control section 8 having a built-in timer and the like, and these constitute selective conduction means for the parallel flow path 4, as will be explained later.

The helium gas flow paths 10, 11.12 each include a stop valve 16, 17.18 and a resistance tube 19, 20.21 in series.

The resistance tubes 19, 20, and 21 are pipes filled with fine particles, and are designed to have a resistance value that is preferably about five times or more greater than the resistance value that is thought to occur in the filters 13, 14, and 15. It's Nishide.

Next, the operation of this apparatus 1 will be explained. For convenience of explanation, as shown in FIG. Let us take as an example the mobile phase of graph L.

In this case, the solubility of each of water W and methanol M in air is very different from the solubility of a mixture thereof in air, so if they are mixed as is, bubbles will be generated, which will adversely affect the analysis.

Therefore, deaeration by this device 1 is necessary.

First, filter 13 is placed in methanol M, filter 14 is placed in water W, and stop valves 16 and 17 are opened.

Stop valve 18 for unused helium gas flow path 12
Keep it closed.

Next, a start command is given to the control section 8.

Then, only the solenoid valve 5 opens.

Here, the bellows valve 3 is opened and adjusted to supply helium gas at a flow rate of, for example, about 100 ml for 7 minutes per liter of solvent.

Since the time required for the air dissolved in the solvent to be replaced with helium to a practically sufficient extent is set in the control unit 8, when that time has elapsed, the control unit 8 automatically closes the solenoid valve. 5 and open the solenoid valve 6.

Therefore, helium gas is supplied at a relatively large flow rate, and when deaeration is completed, the flow rate is automatically switched to a small flow rate.

As a result of the above, the air in water W and methanol M is degassed and helium gas is dissolved instead. Since their solubility in gases is about the same, almost no bubbles are generated when they are mixed, and they can be suitably used as a mobile phase.

Since the flow rate is automatically switched to a small flow rate when deaeration is completed, there is no need for readjustment as in the past, and the operation is reliable.

Furthermore, the resistance values of the filters 13 and 14 in the solvent are different, but compared to these, the resistance values of the resistance tubes 19 and 2 are different.
Since the resistance value of 0 is sufficiently large, these resistance tubes 19.
The flow rate of helium gas is determined depending on 20, which prevents unintended imbalance and stabilizes the flow rate.

Modified embodiments include one that uses nitrogen gas as the degassing gas, one that uses a needle valve or the like instead of the bellows valve 3, and one that opens both the solenoid valves 5 and 6 during the first degassing. , one in which a three-way solenoid valve is used in place of the solenoid valves 5 and 6, and one in which a small flow rate gas flow path 4b is provided across the helium gas cylinder 2 and the branch pipe 9.

As understood from the above explanation, the solvent deaerator of this invention connects a gas flow rate adjustment means to a deaeration gas supply source,
In a solvent deaerator in which a plurality of degassed gas flow paths are connected to the gas flow rate adjustment means via branching means, and a filter means is attached to each end of the degassed gas flow path, a degassing gas supply source and a branch are connected. A small flow rate gas flow path is installed in parallel in the gas flow path between the means or between the gas flow rate adjustment means and the branching means to form a parallel gas flow path, and selective conduction means for the parallel gas flow path is provided. Resistance means with a large resistance are interposed in each gas flow path by means of a filter means, thereby eliminating the need for readjusting the flow rate upon completion of deaeration and ensuring reliable operation.

Further, when degassing various different solvents, each degassing gas flow path is prevented from becoming unbalanced, and the flow rate becomes stable.

[Brief explanation of the drawing]

FIG. 1 is an explanatory diagram of the configuration of one embodiment of the solvent degassing device of this invention. 1... Solvent deaerator, 2... Helium gas cylinder, 3... Bellows valve, 4...
Parallel gas flow path, 4a...Main gas flow path, 4b...
...Small flow rate gas flow path, 5,6...Solenoid valve,
7... Resistance tube, 8... Control section, 9...
... Branch pipe, 10, 11゜12 ... Degassing gas flow path, 13, 14.15 ... Filter, 16
゜17.18・・・Stop valve, 19,20
．． 21...Resistance tube, 22...Pressure gauge.

Claims (1)

[Claims for Utility Model Registration] A gas flow rate regulating means is connected to a degassing gas supply source, a plurality of degassing gas passages are connected to the gas flow rate regulating means via a branching means, and the degassing gas passages are connected to a degassing gas supply source. In a solvent deaerator equipped with a filter means at each tip, a small flow rate gas flow path is installed in parallel with the gas flow path between the deaerated gas supply source and the branching means or between the gas flow rate adjustment means and the branching means. Solvent deaeration characterized in that parallel gas flow paths are formed in parallel gas flow paths, selective conduction means are provided for the parallel gas flow paths, and resistance means having a higher resistance than the filter means is interposed in each of the degassing gas flow paths. Device.