JPS59176677A - Automatic chemical analyzer - Google Patents
Automatic chemical analyzerInfo
- Publication number
- JPS59176677A JPS59176677A JP5072683A JP5072683A JPS59176677A JP S59176677 A JPS59176677 A JP S59176677A JP 5072683 A JP5072683 A JP 5072683A JP 5072683 A JP5072683 A JP 5072683A JP S59176677 A JPS59176677 A JP S59176677A
- Authority
- JP
- Japan
- Prior art keywords
- reagent
- sample
- moving mechanism
- dispenser
- dispensing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/021—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a flexible chain, e.g. "cartridge belt", conveyor for reaction cells or cuvettes
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
【発明の詳細な説明】
（イ）産業上の利用分野
この発明は反応管への試料および１柿以上の試薬の分注
を単一の分注器で行なえるようにした自動分析装置（こ
関する。Detailed Description of the Invention (a) Industrial Application Field The present invention relates to an automatic analyzer (this invention) capable of dispensing a sample and one or more persimmon reagents into a reaction tube using a single dispenser. related.
（ロ）従来技術
従来の自動分析装置においては、第１図−こ示すようを
こ試料容器移動機構（４）ヲこよって順次試料吸引位置
（１）に移動される試料容器（３）の試料を試料分注器
（５）ヲこよって９反応管移動機構位置すると、試薬容
器移動機構（８）により試薬吸引位置初ヲこ試薬容器（
７）が移動切替えられて第１試楽、第２試薬を試薬分注
器（６） （６’）によって分注するように構成されて
いた。このようをこ従来装置では試料を吸引・吐出する
ための試料分圧器と試薬を７Ｊ−圧するための少なくと
も１つ以上の試薬分注器を備えていたために１分注器か
複数必要となってコスト尚となり１分注機構として分注
器の数たけ構成しなければならず構成の単純化が図れな
かった。(B) Prior art In a conventional automatic analyzer, the sample in the sample container (3) is sequentially moved to the sample suction position (1) by the sample container moving mechanism (4) as shown in Figure 1. When the sample dispenser (5) is moved to the 9 reaction tube moving mechanism, the reagent container moving mechanism (8) moves the reagent container (9) to the reagent suction position.
7) was configured to be moved and switched to dispense the first reagent and the second reagent using the reagent dispenser (6) (6'). In order to solve this problem, the conventional device is equipped with a sample pressure divider for aspirating and discharging the sample and at least one reagent dispenser for pressurizing the reagent to 7 J, so one or more dispensers are required. The cost was high, and one dispensing mechanism had to be composed of several dispensers, making it impossible to simplify the structure.
（ハ）目的
この発明は上記問題点を解消し、１つの分注器で試料お
よび１種以上の試薬を分注できるように構成した自動分
析装置を提供することを目的としてなされｔこものであ
る。(C) Purpose This invention has been made with the object of solving the above-mentioned problems and providing an automatic analyzer configured so that a sample and one or more reagents can be dispensed using one dispenser. .
に）構成 次（ここの発明の構成をこついて説明する。) configuration Next (The structure of the invention here will be explained in detail.
この発明をこ係る自動分析装置は単一に設置され分注器
駆動機構によって動作する分注器の分注ノズルを反応管
が反応管移動機構によって順次移動され位置する試料ま
たは試料分注のための２つの位置（こて同一の反応管と
会合するように分注ノズル移動機構によって移動させる
とともをこ、この分注ノズルのノズル口が移動によって
描く軌跡ドＧこ試料吸引位置。This automatic analyzer according to the present invention is for dispensing a sample or a sample in which a reaction tube is sequentially moved and positioned by a reaction tube moving mechanism through a dispensing nozzle of a dispenser that is installed in a single unit and operated by a dispenser drive mechanism. (When the dispensing nozzle is moved by the dispensing nozzle moving mechanism so that the dispensing nozzle is brought into association with the same reaction tube, the nozzle opening of this dispensing nozzle draws a trajectory by moving the sample suction position.)
洗浄位置、試薬吸引位置が各位置するようをこ。Make sure that the washing position and reagent suction position are in their respective positions.
試料容器を載置した試料容器移動機構、洗浄槽、試薬容
器を載置した試薬容器ｅａｌ１機栴を各設置し９反応管
移動機構上の）９ｒ尾反応官をこ分析項目をこ応じて所
冗の試料および試薬を分注するように前記各分注器駆動
機構９反応管移動機構、試料容′４移動機構、試薬容器
移動機構９分注ノズル移動機構を制御する制御機構を設
けて構成されている。Place the sample container moving mechanism with the sample container on it, the washing tank, and the reagent container with the reagent container placed on it, and move the 9r tail reaction tube (on the 9 reaction tube moving mechanism) to the place corresponding to the analysis item. A control mechanism is provided to control each of the dispenser drive mechanisms 9, the reaction tube movement mechanism, the sample container 4 movement mechanism, and the reagent container movement mechanism 9 and the dispensing nozzle movement mechanism so as to dispense redundant samples and reagents. has been done.
け）実施例
以下図面をこ基づいてこの発明の実施例である自動分析
装置（３ついて説明する。Example 3 An automatic analyzer (3) which is an example of the present invention will be described below with reference to the drawings.
第２図はこの発明の１実施例である自動分析装置の構成
の概略を示す模式図である。この自動分析装置は反応管
（１）を載置した反応管移動機構（２）、試料容器（３
）を載置した試料容器移動機＃ （４＋ 、洗浄槽００
１．試薬容器（７）を載置した試薬容器移動機構（８）
９分注器圓を駆動する駆動機構０２）９分注器Ｑｌｌの
ノズル（１４１を移動する分注ノズル移動機構（９）、
これら各機構を制御する制御機構＋１３ｉなどをこよっ
て構成されており。FIG. 2 is a schematic diagram showing the outline of the configuration of an automatic analyzer that is an embodiment of the present invention. This automatic analyzer consists of a reaction tube moving mechanism (2) on which a reaction tube (1) is mounted, a sample container (3)
) Sample container moving machine # (4+, cleaning tank 00
1. Reagent container moving mechanism (8) on which the reagent container (7) is placed
9 Drive mechanism for driving the dispenser circle 02) Dispensing nozzle moving mechanism (9) for moving the nozzle (141) of the 9 dispenser Qll;
It is composed of a control mechanism +13i that controls each of these mechanisms.
分析方法（こよる使用態様（こ合わせて動作する。Analysis method (depends on usage mode).
すなわち、いわゆるエンドポイント法（こよる分析方法
（こおいて（イ）１つ目の試料または試薬分注位置■）
（以下位置の）という）で試料と第１試薬を分注する動
作。（ロ）位置（Ｂ）で試料と第１試薬を分注し、２つ
目の試料または試薬分注位置■（以下位置■という）で
第２試楽を分注する動作、さら昏こレート法による分析
方法をこおいて（ハ）位置（匂で第１試薬を分注し１位
置［Ｆ］で試料を分注する動作、に）位置の）で試料と
第１試薬を分注し９位置■で第２試薬を分注する動作が
０１能である。以下これら使用態様のうち（ロ）とに）
の動作を３ついて説明する。In other words, the so-called end point method (this analysis method (a) first sample or reagent dispensing position ■)
The operation of dispensing the sample and the first reagent at (hereinafter referred to as position). (B) The operation of dispensing the sample and the first reagent at position (B), and dispensing the second sample at the second sample or reagent dispensing position (hereinafter referred to as position), the further colcorate method. Dispense the sample and the first reagent at position (c) (the action of dispensing the first reagent at position [F] and dispensing the sample at position [F])). The operation of dispensing the second reagent at position ■ is 01 function. Among these usage modes (b) and below)
Three operations will be explained below.
まず反応管（１）は反応管移動機構（２）によって位置
ａ３）５位置■２図示しない分析位置へ順次移動される
。位置０３）に位置する反応管（１）に対し１分注ノズ
ル移動機構（９）によって分注ノヌル圓か試薬吸引位１
１１こ移動し１分注ノズル０４１をトげて分注器０旧こ
より指定量の第１試薬を吸引して後、さらをこ分注ノズ
ルＱ４１を位１ｔ（Ｂ）をこ移動して分注器αυにより
ω）位置の反応管（１）へ第１試薬を分注する。分注＃
Ｕ旧よ分注′ｈ駆動機構０２１ヲこよって駆動される。First, the reaction tube (1) is sequentially moved to the analysis position (not shown) by the reaction tube moving mechanism (2). For the reaction tube (1) located at position 03), the dispensing nozzle moving mechanism (9) moves the dispensing nozzle to the reagent suction position 1.
Move the dispensing nozzle Q41 by 1 t (B) and pull up the dispensing nozzle 041 to aspirate the specified amount of the first reagent from the dispenser 0. Dispense the first reagent into the reaction tube (1) at the ω) position using the injector αυ. Dispensing #
It is driven by the drive mechanism 021.
反応ｇ（１）はまだ位置［Ｆ］）（こあり９分注ノズル
（１４１を洗浄槽（１Ｇ＋の洗浄位置（Ｃ）へ移動して
洗浄した後、試料吸引位置印（こ移動させ２分注ノズル
（１４１を下げて分注器（ＩＩＩＧこより指定量の試料
を吸引し、再度位置ＣＢ）へ移動させて試料を分注する
。試料分注後（こ反応管（１）を反応管移動機構（２）
（こより前方へ移動させる。第１試薬と試料とが分注さ
れた反応管（１）が位置■をこ位置すると、試薬容器移
動機構（８）により第２試薬の入った試薬容器（７）が
試薬吸引位置Ｏへ移動される。洗浄槽口αの洗浄位置０
で洗浄した分注ノズル圓を試薬吸引位置０へ移動し、指
定量の第２試薬が分汁器（ｌ旧こより吸引される。分注
ノズル（Ｉ４Ｉを位置■へ移動し分注器（ｌυ（こより
位置■の反応管（１）へ第２試薬を分注する。これら動
作（こより１つの分注器で試料、第１試楽、第２試楽の
分注が口Ｊ１ヒと７χる。Reaction g (1) is still in position [F]) (after moving the 9 dispensing nozzle (141) to the washing tank (1G+ washing position (C) and washing it, move it to the sample suction position mark (move this for 2 minutes). Lower the injection nozzle (141), aspirate the specified amount of sample from the pipette (IIIG), and move it again to position CB to dispense the sample. After dispensing the sample (move the reaction tube (1) Mechanism (2)
(Move it forward from here. When the reaction tube (1) into which the first reagent and sample have been dispensed is at position ①, the reagent container moving mechanism (8) moves the reagent container (7) containing the second reagent is moved to reagent suction position O. Cleaning position 0 of cleaning tank opening α
Move the dispensing nozzle circle that has been cleaned with (Dispense the second reagent into the reaction tube (1) at position ①.) These operations (dispensing the sample, the first test sample, and the second test sample with one pipettor are performed 7× from the opening J1).
すなわち９分注ノズル１４１は９分注ノズル移動機栴（
９）により１良線状に移動する反応管（１）と位置出）
と位置■とで会合するようをこ、これら両位置を１Ｔｌ
ａ端とする円弧上を移動するよう（こされており、一方
試料吸引位置囚、洗浄位置Ｃ）、ｉＸ楽吸引位置０は、
この分注ノズル０４が移動する円弧軌跡と交錯する位置
に設定されている。所定の試料・試薬の入った試料容器
（３）、試料容器（７）は、この試料吸引もＬ置（４）
、試薬吸引位ＩＩ１．■に位置するようをこ試料容器移
動機構（４）、試薬容器移動機構（８）【こまって切替
移動されるのである。反応管移動機構（２）による反応
管（１）の移動、試料容器移動機構（４）による試料容
器（３１の切替移動、試薬容器移動機構（８）をこよる
試薬容器（７）の切替移動７公注ノズル移動機構（９）
による分注ノズルＯケの位置の）、試料吸引位置（４）
、洗浄位ｆ！： ｔＱ 、試薬吸引位ｆＩＬ（Ｄ）。In other words, the 9-dispensing nozzle 141 is the 9-dispensing nozzle moving machine (
9) to position the reaction tube (1) that moves in a straight line)
Let's meet at position ■ and place these two positions at 1Tl.
The iX easy suction position 0 moves so as to move on the circular arc defined as the a end.
This dispensing nozzle 04 is set at a position that intersects with the moving circular arc trajectory. The sample container (3) containing the specified sample/reagent and the sample container (7) are also placed in the L position (4) for this sample suction.
, reagent suction position II1. The sample container moving mechanism (4) and the reagent container moving mechanism (8) are located at (2) and are switched and moved in unison. Movement of the reaction tube (1) by the reaction tube movement mechanism (2), switching movement of the sample container (31) by the sample container movement mechanism (4), switching movement of the reagent container (7) through the reagent container movement mechanism (8) 7 Custom-made nozzle movement mechanism (9)
position of the dispensing nozzle), sample suction position (4)
, washing position f! : tQ, reagent suction position fIL(D).
位に■【こわたる移動９分社器躯動機構０２１（こまっ
て駆動される分注Ｋｍ （Ｉｌｌの指にＭ（の試料また
は試薬の吸引・吐出動作は、それぞれ制御慣構＋１３１
Ｇこよって制御される。上記実施例では反応管（１）
は位置の）で試料と第１：Ａ衆か分注さｔ。■ [Moving over 9 minutes The dispensing mechanism 021 (dispensing Km (Ill) that is driven by the fingers of the sample or reagent M) is controlled by the control habit
It is controlled by G. In the above example, the reaction tube (1)
The sample is dispensed at the first position (in position).
位置■で第２試薬が分注されるよう番こ、各機構の動作
が制御されているが、１試薬系のレート測定では１位置
（Ｂ）で試薬を分注し位置■で試料を分注するよう台こ
すれはよく、また１試薬系のエンドポイント法では７位
Ｉｔ ＣＢ）で試料と試薬を分注すればよい。これら各
動作は分析項目とそれに必要な試薬の種類に応じて任意
Ｇこ制御ａＪ能であり、上記分析方法【こよる使用態様
に合わせて動作することができる。The operation of each mechanism is controlled so that the second reagent is dispensed at position ■, but in rate measurement of a one-reagent system, the reagent is dispensed at position 1 (B) and the sample is dispensed at position ■. The table should be easily rubbed when pouring, and in a one-reagent system endpoint method, the sample and reagent can be dispensed at the 7th position (It CB). Each of these operations can be controlled arbitrarily depending on the analysis item and the type of reagent required for it, and can be operated in accordance with the manner of use depending on the analysis method described above.
この発明にかかる自動分析装置の構成は上記に限定され
るものではなく、第３図をこ示すよう（こ反応管（１）
が回転するよう（こされた反応管移動機構（２）Ｇこよ
り順次移動するようにされ。The configuration of the automatic analyzer according to the present invention is not limited to the above, but as shown in FIG.
The reaction tube moving mechanism (2) is rotated so that the reaction tube moving mechanism (2) is moved sequentially from G.
同一の反応管（１）が１回Ｉ肱Ｈに位置（Ｂ）、２凹転
目に位置■（この場合位１ｋ （Ｂ）と■は同じ位置と
なる）に移動位置し９分注ノズ７Ｌ／ ＜１４）は分圧
ノズル移動機構（９）により位１ｔ■）（位置■）。The same reaction tube (1) is moved to position (B) at I elbow H, position (B) at the second concave turn (in this case, position 1k (B) and ■ are the same position), and the dispensing nozzle is moved to position (B). 7L/<14) is moved to position 1t■) (position ■) by the partial pressure nozzle moving mechanism (9).
試料吸引位置囚、此浄位置０．試楽吸引位置０にわたっ
て直線状に移動するようをこ構成してもよい。この場合
も、上記と同様をこ試料容器（３）、試薬容器（７）の
各位置への移動切替２分注器０１１の駆動等は２分析項
目に応じて適宜試料と試薬の分注が行なえるよう蚤こ制
御機構（１３）により制＃されるものである。Sample suction position 0. This cleaning position 0. It may be configured to move linearly across the pleasure suction position 0. In this case as well, the same procedure as above is used to switch the movement of the sample container (3) and reagent container (7) to each position. It is controlled by the flea control mechanism (13) so that it can be carried out.
（へ）効果
この発明【こ係る自動分析装置は２以上のように構成さ
れており、単一の分注器で試料と数種の試薬を分注する
ことができるので、ａ来の自動分析装置（こ比べ安価に
製作でき１分注機構の単純化がｉＪ能となる。(f) Effects of this invention [This automatic analyzer is configured with two or more parts, and a single dispenser can dispense a sample and several types of reagents, so automatic analysis The device (compared to this) can be manufactured at a lower cost, and the simplification of the dispensing mechanism makes it more efficient.
第１図は従来の自動分析装置の構成の概略を示す模式図
である。第２図はこの発明の実施例である自動分析装置
の構成の概略を示す模式図であり、第３図は変形実施例
をボす模式図である。
（１）・・・反応管 （２）・・・反応管移動
機構（３）・・・試料容器 （４）・・・試料容
器移動機構（７）・・・試薬容器 （８）・・・
試薬容器移動機構（９）・・・分注ノズル移動ａ構
（＋０１・・・洗浄槽０ト・・分注器 α２・
・・分注器駆動機構＋１３１ 、・・制御機構
圓・・・分注ノズル囚・・・試料吸引位置
ＣＢ）・・・１つ目の試料または試薬分注位置Ｃ）・・
・洗浄位置 ０・・・試薬吸引位置■・・・２つ
目の試料または試薬分注位置第２図
第３図FIG. 1 is a schematic diagram showing the outline of the configuration of a conventional automatic analyzer. FIG. 2 is a schematic diagram showing the outline of the configuration of an automatic analyzer according to an embodiment of the present invention, and FIG. 3 is a schematic diagram showing a modified embodiment. (1)...Reaction tube (2)...Reaction tube moving mechanism (3)...Sample container (4)...Sample container moving mechanism (7)...Reagent container (8)...
Reagent container movement mechanism (9)...dispensing nozzle movement a mechanism
(+01...Cleaning tank 0...Dispenser α2...
・・Dispenser drive mechanism +131 ・・Control mechanism
Circle...Dispensing nozzle prisoner...Sample suction position CB)...First sample or reagent dispensing position C)...
・Washing position 0... Reagent suction position ■... Second sample or reagent dispensing position Fig. 2 Fig. 3
Claims (1)
、試薬分圧位置２分析位１作へ順次移動するようをこさ
れた反応肯移動機格。 （イ）複数の試料容器を載直し、谷試料容器を試薬吸引
位置へ順次移動するようをこされた試料容器移動機構。 （つ）複数の試薬容器を載置し、適当な試薬容器が試薬
吸引位置へ順次移動するよう番こされた試薬容器移動機
構。 に）単一（こ設置された分注器の駆動機構。 オ）前記分注器のノズルか、前記各試料吸引位置。 試料分注位置、試薬吸引−位置、試薬分注位置。 および別途設置された洗浄槽の洗浄位置Ｇこわたって移
動するようにされた分注ノズル移動機構。 Φ）前記反応管移動機構上の所定反応管（こ分析項目（
こ応して所蔵の試料および試薬を分注するするように、
前記各反応管移動機構、試料容器移動機構、試薬容器移
動機構９分注器の駆動機構２分注器ノズル移動機価を制
御する制御機構。[Claims] An automatic chemical analyzer 2 comprising the following configurations. (7) A reaction transport machine in which a plurality of reaction tubes are mounted and each reaction officer is made to sequentially move to a sample partial pressure position, a reagent partial pressure position, two analysis positions, and one analysis position. (a) A sample container moving mechanism configured to reload multiple sample containers and sequentially move the valley sample containers to the reagent suction position. (1) A reagent container moving mechanism on which a plurality of reagent containers are placed and arranged to sequentially move appropriate reagent containers to a reagent suction position. B) Single drive mechanism for the installed dispenser. E) Nozzle of the dispenser or each sample suction position. Sample dispensing position, reagent suction position, reagent dispensing position. and a dispensing nozzle moving mechanism configured to move across the cleaning position G of a separately installed cleaning tank. Φ) Specified reaction tube on the reaction tube moving mechanism (this analysis item (
Accordingly, the samples and reagents in stock will be dispensed.
A control mechanism for controlling the reaction tube moving mechanism, the sample container moving mechanism, the reagent container moving mechanism; 9 the drive mechanism for the dispenser; 2 the dispenser nozzle moving mechanism;
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5072683A JPS59176677A (en) | 1983-03-26 | 1983-03-26 | Automatic chemical analyzer |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5072683A JPS59176677A (en) | 1983-03-26 | 1983-03-26 | Automatic chemical analyzer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS59176677A true JPS59176677A (en) | 1984-10-06 |
Family
ID=12866861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5072683A Pending JPS59176677A (en) | 1983-03-26 | 1983-03-26 | Automatic chemical analyzer |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59176677A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5753662A (en) * | 1980-09-17 | 1982-03-30 | Olympus Optical Co Ltd | Cleaning method for probe |
| JPS5782768A (en) * | 1980-11-10 | 1982-05-24 | Hitachi Ltd | Automatic analyzing device |
-
1983
- 1983-03-26 JP JP5072683A patent/JPS59176677A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5753662A (en) * | 1980-09-17 | 1982-03-30 | Olympus Optical Co Ltd | Cleaning method for probe |
| JPS5782768A (en) * | 1980-11-10 | 1982-05-24 | Hitachi Ltd | Automatic analyzing device |
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