JPS59170771A - Automatic chemical analyzing device - Google Patents

Automatic chemical analyzing device

Info

Publication number
JPS59170771A
JPS59170771A JP4515683A JP4515683A JPS59170771A JP S59170771 A JPS59170771 A JP S59170771A JP 4515683 A JP4515683 A JP 4515683A JP 4515683 A JP4515683 A JP 4515683A JP S59170771 A JPS59170771 A JP S59170771A
Authority
JP
Japan
Prior art keywords
sample
specimen
reagent
dispenser
turntables
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4515683A
Other languages
Japanese (ja)
Inventor
Masayoshi Hirabayashi
平林 正佳
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimadzu Corp
Shimazu Seisakusho KK
Original Assignee
Shimadzu Corp
Shimazu Seisakusho KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corp, Shimazu Seisakusho KK filed Critical Shimadzu Corp
Priority to JP4515683A priority Critical patent/JPS59170771A/en
Publication of JPS59170771A publication Critical patent/JPS59170771A/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

PURPOSE:To enable efficient and automatic analysis of multiple items at a high speed with many specimens by providing plural units of turntables on which plural reaction tubes are circumferentially placed, disposing specimen dispensers and reagent dispensers thereto and driving these. CONSTITUTION:A rack 14 is intermittently fed by two specimen vessels each, and both turntables 12 are intermittently rotated by each angle corresponding to one reaction tube in synchronization with the feed of said rack 14. A specimen (a) is dispensed successively from a specimen vessel 13-1 to the reaction tube 11 on the turntable 12-1 by a specimen dispenser 16-1 during this time and at the same time, a specimen (b) is dispensed successively from a specimen vessel 13-2 into the reaction tube 11 on the turntable 12-2 by a specimen dispenser 16-2. A reagent is successively dispensed by reagent dispensers 19-1, 19-2 into the tubes 11 dispensed therein with the specimen (a) or (b). The latter of the number of inspection items and the number of inspection processings can be preferentially analyzed in this case. If the specimens (a) and (b) are the same specimen, the processing for twice the number of the inspection items is made possible and the time required for the inspection is halved.

Description

【発明の詳細な説明】 この発明は、多数の検体について多項目の分析を高速で
効率よく行なう自動化学分析装置に関する。
DETAILED DESCRIPTION OF THE INVENTION The present invention relates to an automatic chemical analyzer that performs multi-item analysis on a large number of specimens at high speed and efficiently.

自動化学分析装置において、単位時間当りに処理できる
最大検査数は各装置により決まっている。このため、検
査項目を多くすれば必然的に単位時間当りに処理できる
検体数は減少し、反対に単位時間当りの検体処理数を多
くしようとすれば1検体についての検査項目が少なくな
る。そこで、各装置の性格は、この検査項目数と検体数
とによって特徴付けられることとなる。
In automatic chemical analyzers, the maximum number of tests that can be processed per unit time is determined by each device. For this reason, increasing the number of test items will inevitably reduce the number of specimens that can be processed per unit time, and conversely, if you try to increase the number of specimens that can be processed per unit time, the number of test items per specimen will decrease. Therefore, the characteristics of each device are characterized by the number of test items and the number of specimens.

ところが、第3図に示すような従来方式の装置において
は、各検体を検査項目分だけ反応管内に分注し、順次、
次の検体の分注操作へと移っていくものであり、検査項
目数もしくは検体処理数のうち、装置全体としていずれ
を優先させるか、選択することはできなかった。第41
Zに示す装置は、この点に関して、たとえば通常は、4
つの反応ラインを構成する反応管ラック(21)の3ブ
ロツクを1検体の12項目の検査に使用し、一方、反応
管ラック(201ブロツクを1検体4項目までの反応管
(11)として使用することにより、検体項目数を通常
の−とし、検体処理能力を3倍とすることができる。な
お第3図および第4図中、に)はフローセル、(ハ)は
吸引ポンプを示す。
However, in the conventional apparatus shown in Fig. 3, each sample is dispensed into reaction tubes for each test item, and then
The process moves on to the next sample dispensing operation, and it was not possible to select which of the number of test items or the number of samples processed should be prioritized for the entire device. 41st
The device shown in Z typically has 4
Three blocks of reaction tube racks (21) constituting one reaction line are used for testing 12 items of one sample, while reaction tube racks (201 block) are used as reaction tubes (11) for testing up to four items of one sample. By doing so, the number of sample items can be reduced to the usual number, and the sample processing capacity can be tripled.In Figs.

このようにし、て第4図に示すような装置においでは、
検査項目もしくは検体数のうちいずれを優先させるかを
選択できる。しかし、このような装置を使用する場合、
反応管ラックQυ1ブロック中の4つの反応!(11)
についてみると、たとえば1検体について必要とされる
検査項目が2つたりであるときであ−っでも、分析時間
としては4項目全部を分析するときと同じ時間が必要と
なる。従って、このような装置では、効率のよい最適な
分析操作を行なうことができず、高速処理の点で難点が
ある。
In this way, in the device shown in FIG.
You can choose which of the test items or the number of samples to give priority to. However, when using such a device,
4 reactions in 1 block of reaction tube rack Qυ! (11)
For example, even when two or more test items are required for one sample, the analysis time is the same as when analyzing all four items. Therefore, with such an apparatus, efficient and optimal analysis operations cannot be performed, and there are difficulties in high-speed processing.

そこで、この発明は、自動化学分析を行なうに¥4って
、検査項目数もしくは検体処理数のうち、いずれを優先
させるかを選択することかでき、かつ最適化された高速
処理を行なうことができるような自動化学分析装置を提
供するく:とを目的としてなされた。
Therefore, the present invention makes it possible to select which of the number of test items or the number of specimens to be prioritized when performing automatic chemical analysis, and to perform optimized high-speed processing. The aim was to provide an automated chemical analyzer that could perform the following tasks.

以下、第1図および第2図に基づいて、この発明の構成
および実施例につい−(説明する。
Hereinafter, the configuration and embodiments of the present invention will be explained based on FIGS. 1 and 2.

この発明に係る自動化学分相装置は、複数本の反応管(
11)を円周状に載置したターン・テーブル(12)を
複数台設け、各ターン・テーブル(12)ごとに、検体
容器(13)に収容された検体を反応管(]1)に分注
するための検体分注器(16)tl、本と、試薬容器(
17)に収容された試薬を反応管(1])に分注するた
めの試薬分注器(111)を1又は複数本配置し、1又
は2種以上の検体が各別に収容された検体容器03)を
ラック0榎上に列設した検体容器列(15)、および2
種以上の試薬が各別に収容された試薬容器(17)を1
又は2列以上に列設した試桑容器群(18)を、名ター
ン・テーブルに共通のものとするとともに、検体分注操
作の進行に応じてラック04つを移動させることによっ
て検体容器03)が1容器分ずつ、並びにターン・テー
ブル(+2)と同数容器分ずつ間欠的にj幀送されてい
く機構を設けたことを特徴とする。
The automatic chemical phase separation device according to the present invention comprises a plurality of reaction tubes (
A plurality of turntables (12) are provided on which 11) are placed in a circumferential manner, and each turntable (12) divides the sample contained in the sample container (13) into the reaction tubes (1). A sample dispenser (16) TL for dispensing, a book, and a reagent container (
A sample container in which one or more reagent dispensers (111) are arranged for dispensing the reagents contained in 17) into reaction tubes (1]), and one or more types of samples are individually accommodated. 03) on the rack 0 rack, and 2
One reagent container (17) each containing more than one reagent.
Alternatively, the sample container group (18) arranged in two or more rows can be made common to all turntables, and the four racks can be moved according to the progress of the sample dispensing operation (specimen container 03). The present invention is characterized by the provision of a mechanism in which the container is intermittently fed one container at a time, and the same number of containers as the turntable (+2).

第1図および第2図(ま、この発明の1実施例である自
動化学分析装置の構成および動作を説明するだめの模式
図である。このうち第1図は、2台のターン・テーブル
(12)でそれぞれ異なる検体について検査する場合を
示し、また第2図は2台のターン・テーブル(ロ))で
同一の検体について検査する場合を示す。なお、第1図
および第2図では、以下の説明の伸宜のためターン・テ
ーブルOt+か2台の場合を示したが、その台数につい
ては2台に限定されるものではない。
Figures 1 and 2 (well, they are schematic diagrams for explaining the configuration and operation of an automatic chemical analyzer that is an embodiment of the present invention. Of these, Figure 1 shows two turntables ( 12) shows the case where different specimens are tested, and FIG. 2 shows the case where the same specimen is tested with two turntables (b)). Note that although FIGS. 1 and 2 show the case of two turntables Ot+ for the sake of convenience in the following explanation, the number of turntables Ot+ is not limited to two.

まず第1図に示したような場合は、ラック0↓)を2検
体容器分ずつ間欠送りするとともに、両ターン・テーブ
ル02)を1反応管に相当する角度分ずつ、前記ラック
04)の送りに同期させて間欠的に回転させる。この間
に、検体分注器(16−1)によって検体aが収容され
た検体容器(13−1)からターン・テーブル(12−
1)に載置された反応管(11)へ順次検体aを分注し
ていくと同時に、検体分注器(16−2)によって検体
すが収容された検体容器(13−2)からターン・テー
ブル(12−2)に載置された反応管(11)へ順次検
体すを分注していく。そして、検体aまたはbが分注さ
れた反応管01)中に、試薬分注器(19−1)、(1
9−2)によって試薬容器(]7)から検査項目に応じ
た試薬を分注していく。なお、試薬容器(17)は移動
用レーン(イ)に載置され、左右に自在に移動できるよ
うにされている。この第1図に示したような場合には、
2検体について分析が行なわれ、試薬系列も両ターン・
デープル(12−1)、(12−2)で共通となる。
First, in the case shown in Figure 1, the rack 0↓) is intermittently fed by two sample containers, and both turntables 02) are fed by the rack 04) by an angle corresponding to one reaction tube. Rotates intermittently in synchronization with During this time, the sample dispenser (16-1) transfers the sample a from the sample container (13-1) containing the sample a to the turntable (12-1).
At the same time, the sample a is sequentially dispensed into the reaction tube (11) placed in・Sequentially dispense the samples into the reaction tubes (11) placed on the table (12-2). Then, the reagent dispenser (19-1), (1
9-2), the reagent corresponding to the test item is dispensed from the reagent container (]7). Note that the reagent container (17) is placed on the movement lane (A) so that it can be freely moved left and right. In the case shown in Figure 1,
Two samples were analyzed, and the reagent series was changed in both turns.
This is common to Daples (12-1) and (12-2).

−力筒2図に示したような場合は、ラック0彎を1検体
容器分ずつ間欠送りするとともに、両ターン・テーブル
(12−i)、(12−2)を1反応管に相当する角度
分ずつ、前記ラック0脅の送りに同期させて間欠的に回
転させる。この間に、検体分注器(16−1)、(16
−2)によって検体容器(+3)からターン・テープ/
I/(12−1)。
- In the case shown in Figure 2, the rack 0-curvature is intermittently fed one sample container at a time, and both turntables (12-i) and (12-2) are set at an angle corresponding to one reaction tube. The rack is rotated intermittently in synchronization with the feed of the rack 0. During this time, the sample dispenser (16-1), (16
-2) from the sample container (+3) by turning the tape/
I/(12-1).

(12−2)に載置された反応管(11)へ順次同一検
体を分注していく。そして、検体が分注された反応管(
lυ中に、試薬分注器(19−1’)、(19−2)に
よって試薬容器(17)から検査項目に応じた試薬を分
注していく。この第2図に示したような場合には、1検
体についてのみ分析が行なわれ、検査項目数は第1図に
示した場合の項目数の2倍となり、1つのターン・テー
ブルで同様の検査を行なう場合に比べて所要時間が半減
する。
The same sample is sequentially dispensed into the reaction tube (11) placed on the tube (12-2). Then, the reaction tube into which the sample was dispensed (
During the test, reagents corresponding to the test items are dispensed from the reagent container (17) using the reagent dispensers (19-1') and (19-2). In the case shown in Fig. 2, only one sample is analyzed, and the number of test items is twice that of the case shown in Fig. 1. The time required is halved compared to when doing so.

そして第2図の場合は、試薬系列は両ターン・テーブル
(12−1); (12−2)で共通のものを使用でき
ない(但し、試薬容器群(ホ)としては共通)ので、図
示のように試薬容器群(ホ)を2列で構成すればよい。
In the case of Fig. 2, it is not possible to use the same reagent series for both turntables (12-1) and (12-2) (however, the reagent container group (e) is common). The reagent container group (e) may be configured in two rows as shown in FIG.

自動化学分析装置をこの発明のように構成することによ
り、分析を行なうに当って、検査項目数もしくは検体処
理数のうち、いずれを優先させるか、適宜選択すること
ができ、かつ、分析操作の効率化が妨げられることなく
最適な高速処理を行なうことができることとなる。
By configuring an automatic chemical analyzer as in the present invention, it is possible to appropriately select which of the number of test items or the number of samples to be processed should be given priority when conducting an analysis, and the analysis operation can be easily performed. Optimal high-speed processing can be performed without hindering efficiency.

【図面の簡単な説明】[Brief explanation of the drawing]

第1図および第2図は、この発明の1実施例である自動
化学分析装置の構成および動作を説明するための模式図
であり、第1図は2検体について検査する場合、第2図
は1検体について検査する場合を示す。また第3図およ
び第4図は、従来装置の構成および動作を説明するため
の模式図である。 (1υ・・・・・・・・・反応管  (ロ)・・・・・
・・・・ターン・テーブル03)・・・・・・・・・検
体容器  α修・・・・・・・・ラック(15)・・・
・・・・・・検体容器列  (16)・・・・・・・・
・検体分注器(17)・・・・・・・・・試薬容器  
 (+8)・・・・・・・・・試薬容器群(2)ン・・
・・・・・・・試薬分注器第1図 第2図 第3図 2
1 and 2 are schematic diagrams for explaining the configuration and operation of an automatic chemical analyzer that is an embodiment of the present invention. The case where one specimen is tested is shown. Further, FIGS. 3 and 4 are schematic diagrams for explaining the configuration and operation of the conventional device. (1υ・・・・・・Reaction tube (b)・・・・・・
...Turn table 03) ...Sample container α repair ...Rack (15) ...
...Sample container row (16)...
・Sample dispenser (17)・・・・・・Reagent container
(+8)...Reagent container group (2)...
・・・・・・Reagent dispenser Fig. 1 Fig. 2 Fig. 3 Fig. 2

Claims (1)

【特許請求の範囲】[Claims] 複数本の反応管を円周状に載置したターン・テーブルと
、1又は2種以上の検体が各別に収容された検体容器を
ラック上に列設し、検体分注操作の進行に応じてこのラ
ックを移動させ、これによって検体容器が間欠的に順送
されていくようにした検体容器列と、検体容器に収容さ
れた検体を反応管に分注するための検体分注器と、2種
以上の試薬が各別に収容された試薬容器を列設した試薬
容器群と、試薬容器に収容された試薬を反応管に分注す
るための試薬分注器とを備えてなる自動化学分析装置に
おいて、前記ターン・テーブルを一散台設け、各ターン
・テーブルごとに1本の検体分注器と、1又は複数本の
試薬分注器とを配置し、前記検体溶器列および試薬容器
群を各ターン・テーブルに共通のものとするとともに、
検体容器が1容器分ずつ、並びにターン・テーブルと同
数容器分ずつ間欠順送される駆動機構を設けたことを特
徴とする自動化学分析装置。
A turntable on which a plurality of reaction tubes are mounted in a circumferential manner and sample containers containing one or more types of samples are arranged in rows on a rack, and as the sample dispensing operation progresses, A sample container row in which the rack is moved so that the sample containers are intermittently fed sequentially, and a sample dispenser for dispensing the sample contained in the sample container into a reaction tube. An automatic chemical analyzer comprising a reagent container group in which reagent containers each containing one or more types of reagents are arranged in a row, and a reagent dispenser for dispensing the reagents contained in the reagent containers into reaction tubes. , the turntables are disposed in one place, one sample dispenser and one or more reagent dispensers are arranged for each turntable, and the sample dispenser row and the reagent container group are arranged. be common to each turntable, and
An automatic chemical analysis device characterized by being provided with a drive mechanism that intermittently transports sample containers one container at a time and the same number of containers as there are turntables.
JP4515683A 1983-03-16 1983-03-16 Automatic chemical analyzing device Pending JPS59170771A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4515683A JPS59170771A (en) 1983-03-16 1983-03-16 Automatic chemical analyzing device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4515683A JPS59170771A (en) 1983-03-16 1983-03-16 Automatic chemical analyzing device

Publications (1)

Publication Number Publication Date
JPS59170771A true JPS59170771A (en) 1984-09-27

Family

ID=12711399

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4515683A Pending JPS59170771A (en) 1983-03-16 1983-03-16 Automatic chemical analyzing device

Country Status (1)

Country Link
JP (1) JPS59170771A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62218869A (en) * 1986-03-20 1987-09-26 Nitsuteku:Kk Automatic analysing apparatus
JPH01210864A (en) * 1988-02-18 1989-08-24 Jeol Ltd Automatic random access biochemistry analyzing device
JPH0338246A (en) * 1989-07-04 1991-02-19 Ngk Insulators Ltd Method and apparatus for regenerating a plurality of reaction tanks
WO2011122607A1 (en) * 2010-03-30 2011-10-06 シスメックス株式会社 Specimen analysis device and specimen analysis system
JP2011209083A (en) * 2010-03-30 2011-10-20 Sysmex Corp Specimen analyzer
JP2011252725A (en) * 2010-05-31 2011-12-15 Sysmex Corp Specimen analyzing device and specimen analyzing system
JP2013117538A (en) * 2013-02-06 2013-06-13 Sysmex Corp Analysis device and specimen measurement method
CN108325571A (en) * 2018-01-25 2018-07-27 冯斌斌 A kind of bio-pharmaceuticals device

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62218869A (en) * 1986-03-20 1987-09-26 Nitsuteku:Kk Automatic analysing apparatus
JPH0378583B2 (en) * 1986-03-20 1991-12-16 Nittec Co Ltd
JPH01210864A (en) * 1988-02-18 1989-08-24 Jeol Ltd Automatic random access biochemistry analyzing device
JPH0338246A (en) * 1989-07-04 1991-02-19 Ngk Insulators Ltd Method and apparatus for regenerating a plurality of reaction tanks
WO2011122607A1 (en) * 2010-03-30 2011-10-06 シスメックス株式会社 Specimen analysis device and specimen analysis system
JP2011209083A (en) * 2010-03-30 2011-10-20 Sysmex Corp Specimen analyzer
US20130019698A1 (en) * 2010-03-30 2013-01-24 Arkray, Inc. Sample analyzer and method for controlling a sample analyzer
US8641988B2 (en) 2010-03-30 2014-02-04 Sysmex Corporation Sample analyzer and sample analysis system
US9080996B2 (en) * 2010-03-30 2015-07-14 Sysmex Corporation Sample analyzer and method for controlling a sample analyzer
JP2011252725A (en) * 2010-05-31 2011-12-15 Sysmex Corp Specimen analyzing device and specimen analyzing system
JP2013117538A (en) * 2013-02-06 2013-06-13 Sysmex Corp Analysis device and specimen measurement method
CN108325571A (en) * 2018-01-25 2018-07-27 冯斌斌 A kind of bio-pharmaceuticals device

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