JPS59155486A - Portable ice bag with immediate effect - Google Patents

Abstract

PURPOSE:To provide the titled ice bag which can be used at any time and at any place without the need of ice water only by applying external force to break an outer bag when necessary, prepared by tightly putting a specified freezing mixture and a solvent-containing bag into an outer bag. CONSTITUTION:A freezing mixture consisting of ammonium nitrate and urea and a solvent selected from among an aqueous solution of a water-soluble polymeric substance (e.g. gelatin or methylcellulose), gel thereof and water, contained in an inner bag made of a synthetic polymer which has such a strength that it may be readily broken by application of external force when the bag is to be used (e.g. nylon or PVA), are tightly put into an outer bag made of a synthetic polymer which stands external force that breaks the inner bag (e.g. nylon or PVC). The inner bag is broken just before use by applicationof external force. The ice bag is portable and is very useful, since coolingis performed at any time and at any place without the need of ice water.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention involves sealing an ice bag containing a cryogen consisting of ammonium nitrate and urea and a solvent for dissolving it in an outer bag;
The present invention relates to a portable, fast-acting ice pack that is used by applying an external force to the bag when it is not in use to cause the ice bag to burst and bringing a cryogen and a solvent into contact with each other.

More specifically, the present invention relates to a gel and water solution of a water-soluble polymeric substance sealed in a synthetic polymer inner bag having a cryogen consisting of ammonium nitrate and urea and a strength that allows it to be easily ruptured by external force during use. A group consisting of a selected solvent is sealed in a synthetic polymer outer bag that does not rupture under external force that would cause the inner bag to easily rupture, and when in use, an external force is applied to the outer bag to rupture the inner bag. A portable ice pack comprising the use of contacting the cryogen and the solvent.

Conventional ice packs are used by filling ice water into a rubber bag or cooling water in a rubber bag in a refrigerator, but they cannot be used in places where ice water is not available. Therefore, the present inventor completed the present invention as a result of various researches to find a portable ice bag without using ice water at any time and at any place.

The ice container of the present invention contains a cryogen and a solvent separately, and when used, by bringing the cryogen and solvent into contact, the cryogen dissolves in the solvent, and at that time, the cryogen stimulates the generated heat of dissolution, thereby lowering the water temperature. This drop in water temperature is then used as an ice pack.

The cooling effect of the ice pack according to the present invention varies depending on the form weight of the cryogen, the mixing ratio, and the type of solvent in which the cryogen is dissolved.

A mixture of ammonium nitrate and urea is used as the cryogen in the present invention, but the cooling temperature and cooling period vary depending on whether the form is powder, granules, or tablets.
In the order of tablet, granule, and powder, the larger the specific surface area, the lower the cooling temperature and the shorter the cooling period. In addition, by increasing the amount of cryogen used or decreasing the amount of solvent in some cases, the cooling temperature can be further lowered and the cooling period can be slightly extended. By mixing ammonium nitrate and urea in various ratios, the cooling temperature and cooling period can be varied; however, in general, the ratio of both is set at a weight ratio of l = 1.
It is preferred to mix in a ratio in the range of ~3:2, especially 1:2.
At a ratio of 7:13, the cooling temperature decreases the most, so
It is most preferred to use this ratio or a ratio close to it.

The above-mentioned cryogen may be in the form of powder, granules or tablets. When making tablets, commonly known excipients,
For example, starch, cellulose, magnesium stearate, and the like are added in several quantities and compression molded by a known compression molding method. Furthermore, this compression molded product may be further coated with a suitable coating agent. Alternatively, the powder may be microencapsulated by microencapsulation methods to convert it into a form that allows for extended cooling periods.

Water is used as a solvent for cryogens, but the duration of the cooling effect can be extended by adding and dissolving a water-soluble polymer substance in it, so an aqueous solution of a water-soluble polymer substance is usually used. Or it is preferably used as a gel. The above-mentioned water-soluble polymeric substances include known natural or synthetic water-soluble polymeric substances, such as gelatin, agar,
Examples include gum arabic, carrageenan, and methylcellulose. The desirable concentrations of these substances vary depending on the type, but generally it is preferable to use carrageenan at a concentration of 2 to 4 percent, gum arabic at a concentration of 25 to 40 percent, and methylcellulose at a concentration of about 4 to 5 percent. Including.

The above solvent is sealed in a water-insoluble synthetic polymer inner bag so that it does not come into contact with the cryogen until it is used as an ice pack. The nature of this synthetic polymer is that it is a film that is strong enough to be easily ruptured by an external force such as a hand during use, and bags made of nylon or vinyl chloride are usually used. The inner bag is sealed by a known method, such as thermocompression bonding.

Next, the cryogen and the solvent contained in the inner bag are placed in an outer bag made of synthetic polymer and sealed. The outer bag needs to be a strong bag that will not burst under any external force that would easily rupture the inner bag. Such bags are usually made of nylon, vinyl chloride, or sulfur. The outer bag is sealed by a known method, such as thermocompression bonding.

When the outer bag with the cryogen and solvent sealed in this way is used as an ice bag, an external force is applied to the outer bag to burst the inner bag and bring the cryogen into contact with the binder. Since it melts and lowers the water temperature, it can be used as an ice pack.

9. The above ice pack can be used at any time. It is useful as a portable ice pack because it can quickly cool down any place without using ice water.

Next, the present invention will be specifically explained with reference to Examples.

Example l Powdered ammonium nitrate and urea in a weight ratio of 17:1
The duration of the cooling effect was calculated by calculating the total water temperature of the aqueous solution and calculating the total water temperature of the aqueous solution.

The results are shown in Figure 1, and the curves showing the water temperature at each blending amount are indicated by the symbols below.

Cryogen Solvent 39.3g Water 13, '87m
-0-39.3g Water 41.4ml
−〇−60, 3,91/ −Δ−
According to Figure 1, whether the solvent is water or a 2-stroke carrageenan aqueous solution, the temperature drops to below the freezing point (0°C) after 1 to 2 minutes, and the 2-stroke carrageenan aqueous solution is cooler than water. The duration of the effect indicates the amount of time spent. Also, when comparing the time required to maintain the difference between the solvent temperature and room temperature at 13°C or higher, it is approximately 16 to 22 minutes in the case of water.
In the case of aqueous carrageenan solution, it was shown that the time was extended to 24 to 40 minutes. Furthermore, increasing the amount of cryogen added further lowers the cooling temperature and extends the cooling period; this effect is seen between 39.3 and 60g, but above '60.9. Even when added, no effect of further extending the cooling period was observed.

Example 2 Powdered ammonium nitrate and urea in a weight ratio of 17:1
1.8 to 39.3g of cryogen mixed at a ratio of 3 to 39.3g each
3.6% carrageenan aqueous solution, 25-40% gum arabic aqueous solution, 4-5 dimethyl cellulose aqueous solution at 34 and 5 m, and shake and 9. Then, measure the water temperature in each solvent and calculate the duration of the cooling effect Cfc.

The measurement results were as shown in FIG. 2 when using aqueous 2-thicarrageenan solution (-〇-), 30% aqueous Arahiacom solution (-low), and 4% aqueous methylcellulose solution (-△-).

For any solvent, the lower the concentration of the polymer substance, the more
Although the degree of temperature drop increased, when calculating the maintenance time to maintain the difference from room temperature at 13°C or more, there was an optimum concentration for each polymer substance, and for carrageenan, it was 30 minutes at a concentration of 3 to 3.6 degrees, For gum arabic, it took 26 minutes at a concentration of 30%, and for methylcellulose, it took 26 minutes at a concentration of 4%.

Example 3 Powdered ammonium nitrate and urea in a weight ratio of 17:1
1 to 2% magnesium stearate was added to the mixed powder mixed at a ratio of 3 to 3, and compression molded to a diameter of 1 m and a thickness of I.
tM, weight 1.0-1.3. Tablets with a hardness of 2 to 3 were obtained.

39.3 g of a cryogen containing the tablets and the above mixed powder in the weight ratio shown below was added to 34.3 g of a 2% carrageenan aqueous solution, respectively.
51d and shaking, the water temperature of the aqueous solution of each cryogen was measured, and the duration of the cooling effect was calculated. The results are shown in Figure 3, and the curves showing the water temperature for the cryogen at each blending ratio are indicated by the symbols below.

Mixing ratio of cryogen Mixed powder 100: Tablet 0-0- p 40: // 20 -△
-, 60: p 80 - According to Figure 3, as the weight ratio of the tablet increases, the degree of temperature drop decreases, but the maintenance time of the cooling effect gradually increases, and 0.6
It became the longest at a ratio of ~0.65. Further increasing the polymerization rate of the tablets decreased this maintenance time.

Example 4 In the process of manufacturing tablets in Example 3, 4 grams of starch was further added to prepare tablets.

A cryogen 60.3 containing this tablet and the mixed powder described in Example 3 in the following weight ratio: F was added to each aqueous solution of Chicaragenan and shaken, and the temperature of the aqueous solution for each cryogen was measured to calculate the duration of the cooling effect.

The results are shown in Figure 4, and the curves showing the water temperature for the cryogen at each blending ratio are indicated by the symbols below.

Mixing ratio of cryogen: Mixed powder 100: Tablet 〇 -〇-tt
35: //65 -Δ-p
20://80 - According to Low Figure 4,
It has been found that when the weight proportion of the tablets is between 60 and 75 inches, the maintenance time of the cooling effect is extended to 65 minutes.

From the results of Examples 1 to 4, when a mixed powder having a ratio of ammonium nitrate to urea of 17:13 was used, the temperature was significantly lower than the freezing point. The maintenance time of the cooling effect can be extended by using a water-soluble polymeric substance, such as an aqueous carrageenan solution, instead of water and increasing the amount of mixed powder used. Also, if the cryogen is used in tablet form instead of in powder form, the cooling effect will be reduced.
When the powders are mixed and used in an appropriate ratio, it is possible to dramatically extend the time for which the cooling effect (difference from room temperature is 13°C or more) is maintained.

[Brief explanation of the drawing]

Figure 1 is a curve showing the influence of the amount of powdered cryogen used, the amount of water and the solvent amount of 2-thicalageenan aqueous solution on the cooling effect,
Figure 2 is a curve showing the cooling effect when a 2% carrageenan aqueous solution, 30% gum arabic aqueous solution and 4-thimethylcellulose aqueous solution are used as a solvent for the powdered cryogen, and Figure 3 is a curve showing the cooling effect when a 2-thicarrageenan aqueous solution is used as a solvent. Figure 4 is a curve showing the cooling effect at each blending ratio of cryogen powder and tablets containing magnesium stemarate.
2 is a curve showing the cooling effect at various blending ratios of cryogen powder and tablets containing magnesium stearate and starch when an aqueous solution of 1% lanan is used.

Claims (1)

[Scope of Claims] 1) An aqueous solution of a water-soluble polymer substance sealed in a synthetic polymer inner bag having a strength such that it can be easily ruptured by external force during use, a cryogen consisting of ammonium nitrate and urea, and a gel thereof; A group consisting of water and a selected solvent are sealed in an outer bag made of synthetic polymer that does not rupture under external force that would cause the inner bag to rupture easily, and when used, the inner bag is ruptured by applying an external force to the outer bag. A portable ice pack may be used by bringing the cryogen into contact with the solvent. 2), ammonium nitrate and urea in a weight ratio of approximately 1=(~
An ice pack according to claim 1, which is a cryogen comprising a combination in a ratio of 3:2. 3) The ice pack according to claim 2, wherein the cryogen is a powder, granule or tablet. 4) The ice pack according to claim 3, wherein the tablet is a composition obtained by adding an excipient and compression molding. 5) The ice pack according to claim 4, wherein the excipient is starch, cellulose or magnesium stearate. The ice pack according to claim 4, which is a composition in which the tablets are coated with a coating agent. 7) The ice pack according to claim 1, wherein the synthetic polymer inner bag is a bag made of nylon or vinyl chloride. 8) The ice pack according to claim 1, wherein the water-soluble polymeric substance is gelatin, gum arabic, caradanan or methylcellulose. 9) The ice pack according to claim 1, wherein the outer bag made of synthetic polymer is a bag made of nylon or vinyl chloride.