JPS59134707A - Cosmetic - Google Patents

Abstract

PURPOSE:A cosmetic that is prepared by adding a specific aminoacid to urea, thus increasing the stability of urea with time and allowing the urea to exhibit its intrinsic properties of humectation, cell activation and wound curing satisfactorily. CONSTITUTION:The objective cosmetic is composed of urea and more than 1/ 10pts.wt., based on the urea, of at least one selected from neutral aminoacids, acidic aminoacids and alkali metal salts of acidic aminoacids. EFFECT:It is free from ammoniac smell and scarcely causes increase in pH. USE:A base cosmetic for lotion, cream, emulsion, pack, make-up cosmetic such as emulsified lip sticks, foundations, or hair cosmetics such as shampoo or rinse.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a compound (1) in which the stability of urea is improved by blending an amino acid with urea.

When urea is incorporated into a cosmetic phase, it is expected to have a moisturizing effect, a cell activation effect, a wound soothing effect, etc. However, in the presence of water, it gradually decomposes and generates ammonia and carbon dioxide gas, so although it is expected to have various effects, it has rarely been incorporated into cosmetics.

In view of the above circumstances, the present inventors have conducted extensive research and have discovered that the stability of urea over time can be improved by blending a specific amino acid with urea, leading to the present invention.

That is, the present invention provides a cosmetic product that contains (1) urea and (ii) one or more selected from the group consisting of neutral amino acids, acidic amino acids, and alkali salts of acidic amino acids. This is what we provide.

The configuration of the present invention will be briefly described below.

The urea used in the present invention may be any commercially available urea.

The urea formulation 1d is in the range of 01 to 5%.If the water is less than 1%, the effect of urea on the skin will be small, and if the water is more than that, the urea method-Jl, chemical 1% will be less effective. It is outside the scope of one product and is subject to regulations.

The amino acids used in the present invention are neutral amino acids and acidic amino acids, such as glycine, alanine, serine, valine, threonine, aspartic acid, and glutamic acid.

Acidic amino acids may be used in the form of alkaline salts. The counter ion of the salt may be any one, such as an inorganic alkali such as sodium salt, potassium salt, or lithium salt, 1 arginine salt, 1 lysine salt, 1 basic amino acid such as histidine salt, ornithine salt, or basic amino acid such as triethanolamine. Salts of amines and the like can be mentioned. Among these salts, sodium salts and sodium salts are particularly preferred.

In the present invention, one or more of the above-mentioned neutral amino acids, acidic amino acids, and alkali salts of acidic amino acids are selected and used. On the other hand, 1/10 ton: 11" or more is desirable for improving stability. Care must be taken when adding excessive amounts of amino acids, as the amino acids themselves may deteriorate, resulting in discoloration, odor, etc.

Cosmetic bases in which urea and γ-minotsugi can be blended include commonly thought cosmetic bases, such as solubilized systems, emulsified systems, powder dispersion systems, water-oil two-layer cosmetics, and water-oil one-powder systems. After layering 1. Any base material may be used, and it can be used for basic cosmetics such as lotions, emulsions, cream packs, emulsifiers, etc.
Make-up cosmetics, shampoo, etc.
hair cosmetics such as conditioners and hair tonics)
The effect of the present invention is that urea is contained in the form of an aqueous solution.
t/). The concentration of the urinary tract aqueous solution is arbitrary. Further, as described above, even if the urea aqueous solution is in the form of an emulsion with the oil phase, there is no problem and the effects of the present invention can be exhibited. However, if the bulking agent itself is basic, the acceleration of decomposition by the basic substance h' may be greater than the stability maintaining effect by the 7' amino acid, which is not preferable.

The cosmetics of the present invention may contain humectants, thickeners, preservatives, emulsifiers, anti-aging agents, sequestering agents, ultraviolet absorbers, powders, etc., as necessary, within the range that does not impair the effects of the present invention. Auxiliary ingredients, colorants, and fragrances can be added.

According to the present invention, when urea and a 40% amino acid are simultaneously blended into a cosmetic, the urea's red 1-1 stability is significantly improved compared to when the amino acid is not used in combination. In other words, 1) γ-monitoring due to decomposition of urea rapidly increases -L, but when used in combination, there is an effect such that pH-H hardly increases. The effects of the present invention cannot be obtained with basic amino acids such as

Next, the present invention will be explained in more detail with reference to practical failures and comparative examples, but the present invention is not limited thereto.

(Margin below) Examples 1 to 3, Comparative Examples 1 to 3 ■ ■ [Base material - Lotion] Ethanol 13.0wt%
1.3-Butylene glycol 1o.

P, O, E (50) oleyl ether
08 Preservatives Suitability: 1 Fragrance
Suitable: 1"L" - Add the registered ingredients, urea and additives, and add purified water in an amount to make the total volume 100.

Odor change: Odor of product stored at 50°C for 1 month. C mark indicates no ammonia odor. The X mark has an ammonia odor.

Determination of urea) iY value...50''C1 Determination of urea jI', c value of stored product. Based on high performance liquid chromatography method.

When compared with the example in which amino acid was added, that is, Example 1.2.3, p11 change, ammonia, constant; 1;: value, etc.
Evaluation item 1-1 is significantly inferior. Both pH change and odor change
It is preferable to have a lower quantitative value, and a higher quantitative value is preferable.
] Night cream (weight%) A, Setanol 40 Vaseline
70 squalane
21.0 Glycerin mo/fatty acid ester z
2Tween60 j
? , 8 Isopropyl myristate 60 Ethylparaben 03 Fragrance
02B, glycerin
100 propylene glycol 5
0 urea 30 glycine
2+0 purified water
The raw material for the oil phase belonging to 365A and the raw material for the aqueous phase belonging to B are heated to 70°C and completely dissolved, and then the oil phase is mixed into the water phase and emulsified using an emulsifier. Finish the emulsion using a heat exchanger i7. ．． ', 30
After cooling to 'C, filling is performed.

A formulation in which only amino acids were removed from the formulation described in Example 4 was prepared at the same time as Example 4, and after being stored at 40°C for 2 months, urea was determined.
While 7 to 99% remained, those from which amino acids were removed decreased to 86 to 88%.

(Left below) Example 5 Foundryon (wt%) A,
Setanol 35 Deodorizing/phosphorus 40 Jojoba oil
50 Vaseline Z
, 0 squalane 6゜glycerin fatty acid ester 2-5P, O, E, (
60) Hydrogenated human oil 15P, O, E, (
25) Cetylneedle 10propylparaben
03 incense f11.
0.2B, glycerin
30 Propylene Glycol 800.3
2wt%, Fe, O, 0.08wt95. Fe0(OH
)0.4wt%) Urea 2
-O alanine 20 monosodium glutamate lO purified water
, 60 manufacturing method is based on Example 5.

A formulation in which only amino acids were removed from the formulation described in Example 5 was prepared at the same time as Formulation Example 2, and after storage at 0°C for 2 months, urea was quantified.
~98% remained, whereas that from which amino acids were removed was reduced to 89-90%.

Patent Applicant Kenseido Co., Ltd. Procedural Amendment (Voluntary) Roa (■ll 1958 12 Swords 90 Commissioner of the Patent Office Name Kazuto Sugi 1, Indication of Case 1982 Patent Application No. 7689 2, Name of Invention Cosmetics 3. Consideration for amendment 4. Detailed explanation of the invention in the specification subject to amendment , "lactic acid," he says.

that's all

Claims (1)

[Claims] Chemical formula 1 characterized in that it contains (1) urea and (ii) one or more selected from the group consisting of neutral amino acids, acidic amino acids, and alkali salts of acidic amino acids.
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