JPS5867689A - ６−アミジノ−９−置換ベンジルプリン類 - Google Patents

６−アミジノ−９−置換ベンジルプリン類

Info

Publication number
JPS5867689A
JPS5867689A JP57164181A JP16418182A JPS5867689A JP S5867689 A JPS5867689 A JP S5867689A JP 57164181 A JP57164181 A JP 57164181A JP 16418182 A JP16418182 A JP 16418182A JP S5867689 A JPS5867689 A JP S5867689A
Authority
JP
Japan
Prior art keywords
compound
lower alkyl
poultry
structural formula
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57164181A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0438752B2 (enExample
Inventor
ドナルド・ダブリユ・グラハム
ギヤリイ・エツチ・ラスムソン
リチヤ−ド・エル・トルマン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5867689A publication Critical patent/JPS5867689A/ja
Publication of JPH0438752B2 publication Critical patent/JPH0438752B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP57164181A 1981-09-28 1982-09-22 ６−アミジノ−９−置換ベンジルプリン類 Granted JPS5867689A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/306,112 US4407802A (en) 1981-09-28 1981-09-28 6-Amidino-9-substituted benzyl purines
US306112 1989-02-06

Publications (2)

Publication Number Publication Date
JPS5867689A true JPS5867689A (ja) 1983-04-22
JPH0438752B2 JPH0438752B2 (enExample) 1992-06-25

Family

ID=23183865

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57164181A Granted JPS5867689A (ja) 1981-09-28 1982-09-22 ６−アミジノ−９−置換ベンジルプリン類

Country Status (4)

Country Link
US (1) US4407802A (enExample)
EP (1) EP0076127B1 (enExample)
JP (1) JPS5867689A (enExample)
DE (1) DE3264061D1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6294541B1 (en) 1996-06-06 2001-09-25 Euro-Celtique S.A. Purine derivatives having phosphodiesterase IV inhibition activity
DE19882893T1 (de) 1997-12-12 2001-02-22 Euro Celtique Sa Herstellung von 3-substituierten Adeninen
US6319928B1 (en) 1998-11-30 2001-11-20 Euro-Celtique, S.A. Purine derivatives having phosphodiesterase IV inhibition activity
BR0011182A (pt) 1999-04-02 2003-06-10 Euro Celtique Sa Derivados de purina tendo atividade inibidora de fosfodiesterase iv
RU2178594C2 (ru) * 1999-11-12 2002-01-20 Закрытое акционерное общество "Фирма "Тэнси-техно" Способ записи в блок энергонезависимой памяти и устройство для его осуществления
FR2833813B1 (fr) * 2001-12-26 2005-08-26 Phytosynthese Complement alimentaire destine a l'animal
FR3078629B1 (fr) 2018-03-12 2020-07-31 Adisseo France Sas Additif alimentaire a base de saponines pour le traitement de la coccidiose

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1310454A (fr) * 1959-03-24 1962-11-30 Schering Ag Procédé de préparation de formamidines nu. nu'-trisubstituées
US3846426A (en) * 1971-03-03 1974-11-05 Int Minerals & Chem Corp 6-amino-9-(substituted benzyl) purines and their n{11 oxides
US3862189A (en) * 1973-08-14 1975-01-21 Warner Lambert Co Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
GB1534163A (en) 1976-07-28 1978-11-29 Merck & Co Inc Adenine derivatives
US4189485A (en) * 1977-08-23 1980-02-19 Takeda Chemical Industries, Ltd. Purine derivatives

Also Published As

Publication number Publication date
JPH0438752B2 (enExample) 1992-06-25
DE3264061D1 (en) 1985-07-11
EP0076127B1 (en) 1985-06-05
US4407802A (en) 1983-10-04
EP0076127A2 (en) 1983-04-06
EP0076127A3 (en) 1983-05-25

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