JPS5850212B2 - ポリペプチドノセイゾウホウ - Google Patents
ポリペプチドノセイゾウホウInfo
- Publication number
- JPS5850212B2 JPS5850212B2 JP50010878A JP1087875A JPS5850212B2 JP S5850212 B2 JPS5850212 B2 JP S5850212B2 JP 50010878 A JP50010878 A JP 50010878A JP 1087875 A JP1087875 A JP 1087875A JP S5850212 B2 JPS5850212 B2 JP S5850212B2
- Authority
- JP
- Japan
- Prior art keywords
- phe
- arg
- water
- ala
- tyr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims description 76
- 102000004196 processed proteins & peptides Human genes 0.000 title description 17
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- AOIZTZRWMSPPAY-KAOXEZKKSA-N Tyr-Thr-Pro Chemical compound C[C@H]([C@@H](C(=O)N1CCC[C@@H]1C(=O)O)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)O AOIZTZRWMSPPAY-KAOXEZKKSA-N 0.000 claims description 3
- 229940043230 sarcosine Drugs 0.000 claims description 3
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- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- VTDLJMATIHSOTR-RSAXXLAASA-N n-cyclohexylcyclohexanamine;(2s)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-2-(phenylmethoxycarbonylamino)hexanoic acid Chemical compound C1CCCCC1NC1CCCCC1.CC(C)(C)OC(=O)NCCCC[C@@H](C(O)=O)NC(=O)OCC1=CC=CC=C1 VTDLJMATIHSOTR-RSAXXLAASA-N 0.000 description 1
- PSZYNBSKGUBXEH-UHFFFAOYSA-N naphthalene-1-sulfonic acid Chemical compound C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 PSZYNBSKGUBXEH-UHFFFAOYSA-N 0.000 description 1
- 229910052759 nickel Inorganic materials 0.000 description 1
- DANUORFCFTYTSZ-BIBFWWMMSA-N nigericin Chemical compound C([C@@H]1C[C@H]([C@H]([C@]2([C@@H](C[C@](C)(O2)C2O[C@@](C)(CC2)C2[C@H](CC(O2)[C@@H]2[C@H](C[C@@H](C)[C@](O)(CO)O2)C)C)C)O1)C)OC)[C@H]1CC[C@H](C)C([C@@H](C)C(O)=O)O1 DANUORFCFTYTSZ-BIBFWWMMSA-N 0.000 description 1
- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 125000006503 p-nitrobenzyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1[N+]([O-])=O)C([H])([H])* 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000010647 peptide synthesis reaction Methods 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 108010065135 phenylalanyl-phenylalanyl-phenylalanine Proteins 0.000 description 1
- UYWQUFXKFGHYNT-UHFFFAOYSA-N phenylmethyl ester of formic acid Natural products O=COCC1=CC=CC=C1 UYWQUFXKFGHYNT-UHFFFAOYSA-N 0.000 description 1
- PTMHPRAIXMAOOB-UHFFFAOYSA-N phosphoramidic acid Chemical compound NP(O)(O)=O PTMHPRAIXMAOOB-UHFFFAOYSA-N 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 239000011541 reaction mixture Substances 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000007929 subcutaneous injection Substances 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229950000244 sulfanilic acid Drugs 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-M toluene-4-sulfonate Chemical compound CC1=CC=C(S([O-])(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-M 0.000 description 1
- 125000002088 tosyl group Chemical group [H]C1=C([H])C(=C([H])C([H])=C1C([H])([H])[H])S(*)(=O)=O 0.000 description 1
- 108010005834 tyrosyl-alanyl-glycine Proteins 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50010878A JPS5850212B2 (ja) | 1975-01-24 | 1975-01-24 | ポリペプチドノセイゾウホウ |
| AU79046/75A AU482894B2 (en) | 1974-03-26 | 1975-03-13 | Novel polypeptides |
| US05/560,092 US4001199A (en) | 1974-03-26 | 1975-03-19 | Novel polypeptides useful for treating diabetes and hypercholesteremia |
| CS751971A CS189694B2 (en) | 1974-03-26 | 1975-03-22 | Method of producing novel polypeptides |
| IE651/75A IE40877B1 (en) | 1974-03-26 | 1975-03-24 | Polypeptides |
| NL7503519A NL7503519A (nl) | 1974-03-26 | 1975-03-24 | Werkwijze ter bereiding van nieuwe polypeptiden. |
| FR7509114A FR2274604A1 (fr) | 1974-03-26 | 1975-03-24 | Nouveaux polypeptides et leur procede de preparation |
| AT223975A AT348153B (de) | 1974-03-26 | 1975-03-24 | Verfahren zur herstellung von neuen polypeptiden |
| SE7503471A SE7503471L (enrdf_load_stackoverflow) | 1974-03-26 | 1975-03-25 | |
| CA223,059A CA1059993A (en) | 1974-03-26 | 1975-03-25 | Polypeptides |
| DE19752513057 DE2513057A1 (de) | 1974-03-26 | 1975-03-25 | Neue polypeptide und verfahren zu ihrer herstellung |
| GB12365/75A GB1499764A (en) | 1974-03-26 | 1975-03-25 | Polypeptides |
| NO751044A NO751044L (enrdf_load_stackoverflow) | 1974-03-26 | 1975-03-25 | |
| DK126275A DK126275A (enrdf_load_stackoverflow) | 1974-03-26 | 1975-03-25 | |
| ES435990A ES435990A1 (es) | 1974-03-26 | 1975-03-25 | Un metodo para producir nuevos polipeptidos. |
| CH389775A CH618959A5 (enrdf_load_stackoverflow) | 1974-03-26 | 1975-03-26 | |
| SU7502127597A SU577975A3 (ru) | 1974-03-26 | 1975-03-26 | Способ получени полипептидов |
| HU75TA1351A HU175306B (hu) | 1974-03-26 | 1975-03-26 | Sposob poluchenija novykh polipeptidov |
| FI750925A FI750925A7 (enrdf_load_stackoverflow) | 1974-03-26 | 1975-03-26 | |
| US05/726,052 US4073890A (en) | 1974-03-26 | 1976-09-23 | Novel polypeptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP50010878A JPS5850212B2 (ja) | 1975-01-24 | 1975-01-24 | ポリペプチドノセイゾウホウ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5186440A JPS5186440A (enrdf_load_stackoverflow) | 1976-07-29 |
| JPS5850212B2 true JPS5850212B2 (ja) | 1983-11-09 |
Family
ID=11762575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50010878A Expired JPS5850212B2 (ja) | 1974-03-26 | 1975-01-24 | ポリペプチドノセイゾウホウ |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5850212B2 (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5963208U (ja) * | 1982-10-22 | 1984-04-25 | 有限会社末廣産業 | ノツクダウン式家具の連結金具 |
-
1975
- 1975-01-24 JP JP50010878A patent/JPS5850212B2/ja not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5963208U (ja) * | 1982-10-22 | 1984-04-25 | 有限会社末廣産業 | ノツクダウン式家具の連結金具 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5186440A (enrdf_load_stackoverflow) | 1976-07-29 |
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