JPS5844412A - Microscope mounting base - Google Patents

Abstract

PURPOSE:To securely fix a prepared specimen without breaking it by providing an X and an Y lever which turn in accordance with the movement of a stage and also press the circumference of the preparation on the stage. CONSTITUTION:On the top surface of an arm part 41x of the stage 41a of a microscope mounting base 4, preparation stoppers 41f and 41k are provided to abut to one circumference of a preparation A when the preparation A is fixed. On the top surface of an arm part 41y, a preparation stopper 41k is provided to abut to the other circumference of the preparation A. Those stoppers are rollers supported pivotally to shafts and have a kind of abacus beads to press the preparation against planes of the arm parts when the stoppers are pressed. For the purpose, an X lever 41b and an Y lever 41g are turned to press the preparation against the stoppers with trapezoidal rollers 41e and 41j, thus fixing the preparation.

Description

DETAILED DESCRIPTION OF THE INVENTION - This invention relates to a microscope stage used to examine cells, etc., and in particular relates to the improvement of the Clan 1 mechanism of the preparation. As the automation of tests in the field of diagnosis and blood image classification progresses, a high degree of precision is required of mechanisms for transporting slides, etc. 4'l'pcs Microscope stage prefabricated 2. - Regarding the clamping mechanism, first,
It is important to have good reproducibility of the operation.◇ In order to meet these demands, an opening is provided at one end of the stage, and seven specimen guide pawls are provided in this opening i1, and the preparation A microscope stage having a preparation clamping mechanism equipped with a clamp lever that presses the plate/haler in one direction when inserted was previously proposed (see Japanese Utility Model Publication No. 52-56049).

However, although the pre-puff clamp mechanism described in the above publication is extremely effective, it has been discovered that it has the following problems:
IIIK, the structure is simple as it uses a linear movement system of an autochanger to push in and push back the preparations, and opens and closes a single 2-inch lever.
It was difficult to adjust the elasticity of the ngrepa. In other words, in order to smoothly put in and take out the preparatory)
It is better that the elasticity is smaller, but on the other hand, it is better for K to be larger than the elasticity of the lever in order to stably clamp the slide once it has been inserted. Despite this, the elasticity of one clamp lever is
It was not possible to make appropriate changes and adjustments independently between when the preparation was taken in and out and when it was identified. Second, since the clamp lever clamps the slide by contacting the corner of the slide, the corner of the slide may break off, and the resulting glass pieces may remain on the microscope stage, interfering with various operations. This invention was made in view of the above circumstances, and is capable of reliably fixing the microscope stage in a fixed position.
It is an object of the present invention to provide a microscope stage having such a preparation clamping mechanism that does not damage the preparations.

The basic principle of this invention Hia is 1 depending on the movement of the stage.
- At the same time, the edge 2211 of the creperate on the stage
The X lever and Y lever that press the ilt are located at the crotch.Next, an eleventh embodiment of the present invention will be described with reference to the drawings.

18th! ! 1 is a plan view showing the arrangement of a microscope stage and peripheral devices thereof according to the present invention in an Irt and sample testing apparatus.

In the figure, 1 is a preparation magazine for storing a large number of preparations; 2 is a preparation storage section for loading and unloading desired preparations from the preparation magazine 1;
3 is a preparation transport mechanism that adsorbs and transports the preparations using a vacuum pad 31; 4 is a microscope stage o
A is a slide placed on the microscope stage 4, and A' is a slide taken out from the slide magazine 1 by the operation of the slide accommodating section 2. Indicates the position at which n1 transport is started.

The preparation magazine 1, preparation storage 112
and the preparation transport mechanism 3 is disclosed in Japanese Unexamined Patent Publication No. 54
Since f' described in Japanese Patent Application No. 8!1887 can be suitably used, a detailed explanation thereof will be omitted.

Figure II2 is a plan view showing a microscope stage which is an embodiment of the present invention, Figure J1!3 is a partially cutaway front view showing the microscope stage, and Figure 4- is a plan view showing the microscope stage. FIG. 3 is a partially cutaway left side view shown in FIG.

As shown in IK211, the microscope stage 4 first consists of a mechanism for moving the stage 41a on the Grepatuto t stage 41g, a mechanism for moving the stage 41α in the X direction in the figure, and a mechanism for moving the stage 414Et in the Y direction in the figure. Is it equipped with a mechanism? The clamping mechanism mainly includes the stage 41g, the X lever 41b, and the Y lever 41! , Pleno (lard stopper 417.41At-equipped with 0 stage 4
1#! As shown in 1I211, prepara) At
The rack has an opening 1f141jEx formed in the arm 541y and an opening 1f141jex formed in the arm 541y and an opening s41 formed in the base 41g, which extend opposite each other from the base 114111+ so that the rack can be passed. It is a flat plate having a concave outline as a whole, and has an arm of the stage 414I @ 415 (D upper surface has a preparation At-J5 that comes into contact with the edge 1iK of the preparation A when fixing it. Preparation stopper 41f
. A preparation stopper 41& is provided so as to face the
'c%Aru. Preparation stoppers 41/, 41 have −
As shown in FIG.
It is a rL roller that is pivotally supported on an upright shaft, and its low 2
At least, the surface of the preparation stopper is the arm 54.
It is formed at an angle of less than 90° with respect to the plane of 1J, and in this embodiment, it has a shape similar to an abacus ball.

The preparation stopper 417.41 is used to change the shape of the roller so that at least the contact surface is less than 90 degrees with respect to the plane of the arm @ 41J.
When AK preparation A is pressed, one preparation stopper 41/41A stops the preparation A arm 114.
This is to prevent the preparation A from rising above the stage 41g by pressing against the planes 1g and 41y. In addition, the preparation stopper 41/,
4U has a structure in which a roller is pivotally supported on the shaft of the arms 41JF and 41y, which is erected on the soil surface. This is because when the slide A is fixed in place, the edge of the slide A and the roller are This is to prevent wear of the end face of the preparation A due to sliding friction by making the point have rolling friction, and also to allow the preparation to be smoothly pressed by the X lever and the Y lever. As shown in the second @, a shaft 41C is erected on the upper surface of the
At one end of the OX lever 41A, a folded part of the X lever 41A forming an inverted shape is rotatably supported.
At-Sono-ra 41- for pressing in the X direction in Fig. 2
is rotatably supported, and as shown in FIG.
The protruding bottle 41SL is fixed, and the X lever 41
At the other end of h, rotate the X lever 41A in the direction C in FIG. -) A biasing member such as a tension spring 41d that biases the edge S of A is attached to the roller 41#, as shown in FIG. is arm 541
It has an inverted truncated conical shape formed at an angle of less than 90° with respect to the y plane, and the reason for forming it in this way is the same as in the case of the rollers in the preparation stoppers 41f and 41kK.

As shown in FIG. 2, a shaft 411 is erected on the upper surface of the base 41m on the stage 41g, and this shaft 41AK is connected to the Y lever 41! which forms an inverted shape. is bent lB
It is rotatably supported via t. Y lever 41 y
OIt K 14s Preparation? -) AtaI2 oy in the figure
A dangerous roller 41j that presses in the direction is rotatably supported n 9, YL/Pa 41! The other end is c n t IR
As shown in FIG.
Also, Y lever 41! As shown in FIG. 2, between the pivot point and the other end, there is a Y lever 41ftl12 in the B direction! 1
cast, roller 41. ? A biasing member such as a tension spring 41B that biases the edge portion of the preparation A is attached to the roller 41jFi, 4-
For the same reason as in the case of 241-, the tension 9 spring 41j and the tension 9 spring 41g0 have a similar shape, and the biasing forces of the tension 9 spring 41j and tension 9 spring 41g0 are mutual. , Y lever 41! The biasing force of the tension spring 41d is set to be weaker than the biasing force of the tension spring 411 so that the pressing force is 100 grams.

The reason why the biasing forces of the tension springs 41d and 418 are different as shown in FIG.
After holding it lightly, Y lever 41! This is to forcefully push the brake paratom into the predetermined position and fix it. As described below, the X lever 41b and the Y lever 41y are arranged to fix the preparation arm at a predetermined position on the stage A in conjunction with the movement of the stage 41α in the direction opposite to the X direction in FIG. The mechanism for moving the stage 416 in the X direction (i in FIG. 112) is the opposite direction, as shown in FIGS.
1 Lead screw 41P, coupling 41q.

Nut 41Q and guide member 41! , 4111t- The base 41s has a substantially U-shaped cross section as shown in FIG. As shown in the figure, a motor 41r is installed on the right side 11 of the base 41%, and the motor 41rK is fixed with a lead screw 41P extending in the X direction in Figure 2 through a coupling 41g. 417) Kd, the nut 41Q fixed to the bottom surface of the base s4 noodle of the stage 41g is screwed together.
As shown in FIG. 4, a guide member 4111 is provided,
Also, stage 4160 units I! A guide member 41j is also provided on the lower surface of the guide member 41#, and a bone 41t is interposed between the guide member 41 and the guide member 411. Then, the motor 41 r'i is recommended.
By one rotation of p, the guide member 41+arcff
I-Tute x? - Shi 41a Ka 112 Garden and Uta 3 In the diagram, i in the X direction can be moved in the opposite direction.

Further, as shown in the figure, a lever stopper 41# is provided inside the left side of the base 41, and the guide member 41 is connected to the stage 41! As it moves to the left from the cloth in FIG.
-/ 41a As Yt moves to the left, the lever stopper 41# presses the bottle and turns the X lever 41A in the direction opposite to the B direction as shown in Fig. 142. As shown in FIG. 4, the base 41nVcri is provided with a lever stopper 411, and as the stage 416 moves from position to left in FIG. 2 along the guide member 41, it stops at a certain point. The lever stopper 411 comes into contact with the bottle 41 of the X lever 41h, and the stage 4 still remains.
As you move 1G to the left, the lever stopper 4111 presses the bottle 41! As shown in Figures 1 and 2, the X lever 41j6 moves in the direction opposite to the t-C direction. In this case, a certain point where the lever stopper 41JF contacts the bottle of the Y lever 41g and a certain point where the lever stopper 41D
The fixed point where the lever touches the bottle 41 of the X lever 41h is
For example, KY lever 41 comes before X lever 41A! Lupara (Release stopper 41# to release the oppression on A)
The mechanism for moving the 0 stage 411 in the direction Y7j in Figure IN2, which requires setting the position of the lever 41ν appropriately, is based on the base 41s on which the stage 41αt is placed movably in the X direction in Figure 2. Since the mechanism for moving the stage 41#lt-n itself is the same as that of replacing the base 41s in place of the stage 41a, a detailed explanation thereof will be omitted. consists of a base, a motor, a lead screw, a coupling, a nut, a guide member, etc.
Stage 41 @ tfJ112The mechanisms for moving the stage in the Y direction in the figure are collectively indicated by the number -2.0 Note that 5 in Figure 2 indicates the optical axis position of the microscope.Next, The operation of the microscope stage having the above-mentioned configuration will be explained with reference to the drawings in Figure 5 (α) to
(C) is an explanatory diagram showing the order of fixing the pre/(ratom) on the stage 41-.

First, as shown in FIG. 1, the slide (n) Ate pushed out from the gray paper magazine 1 by the action of the slide storage s20 is transported to the slide transport mechanism 3 to the ↓9 microscope area anastomosis 4;rLS#! Figure 2 Snoring and Figure 5 (α)
It is placed on the stage 414 in the state shown in K. In addition, when the preparation stage Ak 41aK@ is moved, the stage 414t guide member 41mv needs to be fixed and positioned at the left end in the X direction, as shown in FIG. That's stage 41! When P is positioned as described above, the bottle 41M of the X lever 41b is pressed by the lever stop flange 41v and the X lever 41A is pressed.
is rotated in the direction opposite to the C direction in FIG. 2 against the biasing force of the tension spring 41d, and the Y lever 411 is also rotated in the B direction in FIG. m2 in the same manner as the X lever 41b. This is because -mp 9 is moved in the opposite direction, and as a result, the preparation A can be suitably placed on the stage 41a.

Next, when the stage 41a is moved toward the right end in the X direction by driving the motor 41r as shown in FIG. (2) move in the C direction. Then, Figure 5 (
As shown in b), attach it to the X lever 41h using a friend row'')
41A presses the preparation A against the preparation stopper 417 while moving the edge portion of the ruber) A6). In this case, the X lever 411I and prepara)A
As shown by the dot-and-dash line in FIG.
However, even in such a case, as described below, the 'KY Lever 41! Since the slide A is set in a predetermined position, there is no problem. After this, as shown in FIG. 882, the motor 411
- When the stage 41ai is further moved toward the right end of the direction, the Y lever 41g rotates in the B direction in Figure 2. Then, the Y The roller 41j with salt 9 applied to the lever 41! presses the preparation A against the preparation stopper 41j while rolling on the edge St of the preparation A. In this case, the tension spring 41g that biases the Y lever 41! Since the force is larger than the biasing force of the tension spring 41d that biases the X lever 41hYt (for example, the former is 100 grams heavy and the latter is 20 grams heavy), the X lever 41A is preparalleled in the X direction) At is pressed. Despite the fact that Y lever 4
1! can reliably suppress slide A in the Y direction. Moreover, the preparation stopper 41/, 41&
roller, X lever 41hO roller 41# and Y lever 4
1! Since the rollers 41j are each rotatably supported, the preparatom is moved by the pressing force to the stage 41α.
Even if the top of the slide is displaced, the g-2 slides on the edge of the slide A and moves without causing any friction, thereby damaging the edge S of the slide A and scattering glass pieces and powder. There is no.

After fixing the preparation A at a predetermined position on the stage 41B, in order to move the preparation A to the base axis position 5 of the microscope as shown in FIG. Move it again! 112 The stage 41 is moved appropriately in the Y direction by the machine 111 indicated by number 42 in the figure. As a result, the preparation A can be positioned at the optical axis position 5 of the microscope. After observing the sample on the surface, removing the At stage 41g can be accomplished by following the above steps in reverse.

Although one embodiment of this invention has been described in detail above, this invention is not limited to the above embodiment, and includes various modifications within the scope of the gist of this invention. Mona (A.

For example, in the above implementation fl@, the X lever 41h and the Y lever 41! The movement is in the X direction of the stage 41@
and the moving mechanism in the opposite direction, but as a modified example, the X lever 41A and the Y lever 41!
The operation may be linked to a mechanism for moving the stage 41@ in the Y direction, or may be linked to a mechanism for moving the stage 41g in the X direction and a movement mis in the Y7j direction. .

In the above embodiment, X/<a1ho pressing force is ICY lever 41! Although the configuration is such that the pressing force is larger, as a modification, tLt may be reversed to 7t%. In this case, it goes without saying that the procedure for fixing the preparations is to first fix the preparation A with the Y reno (41!) and then fix it with the X lever 41h.

According to the invention described in detail above, the specimen testing device that automates cytodiagnosis and blood image classification can achieve the following effects:
The device requires a review function to show the cells, etc. that could not be determined to the doctor and encourage the doctor's decision.The review function requires the position of cells to be reexamined on a single slide. The position is stored in the device, and recalled from the storage device when the tube is reviewed. According to this WIA, it is possible to mount the slide in a predetermined position on the microscope stage with extremely high reproducibility. In order to focus the microscope in the specimen testing equipment in the shortest possible time, it is necessary to hold the slide without the slide rising above the stage surface.According to this invention, when holding the slide, Preparation stopper and X lever that come into contact with
Since the roller surface of the X-lever is at an acute angle to the stage surface, the pressing force from the roller acts perpendicularly to the preparation surface from top to bottom, and by pressing the glenoid against the stage surface. (Also, when pressing the preparation with a roller, according to this invention, the roller can prevent the lard from floating up)
Since the pre/< lard and the roller rub against each other, glass powder and glass fragments caused by breakage of the preparation will not be scattered on the stage surface as in the conventional case. In the end, according to Jin's invention, the slide can be mounted on the Gleba or F-)k microscope stage without damaging the slide due to reproducibility.◇

[Brief explanation of the drawing]

FIG. 1 is a plan view showing the arrangement of a microscope stage according to the present invention and its peripheral equipment in a sample testing apparatus, FIG. II2 is a plan view showing a microscope stage tube according to an embodiment of the present invention, and FIG. 4 is a partially cutaway front view showing the microscope stage, FIG. 4 is a partially cutaway left side view showing the microscope stage, and FIGS. 5(-) to (C) show slides placed on the stage. FIG. 3 is an explanatory diagram showing the order of fixing. 4... Microscope stage, 41α... Stage, 41h
...X lever, 417...X lever, 41f, 41k.
...Preparation 2-) Stopper, 411.41 No..Roller, A...Preparation〇Representative Patent attorney Noriyuki Chika (and 1 other person) Fig. 3 Fig. 4 Fig. 1P

Claims (1)

[Scope of Claims] (-1) In a microscope stage that is installed in the specimen testing apparatus 1 and that moves the stages on which the preparation tubes are placed in mutually orthogonal directions to position the preparations under the optical axis of the microscope. , a stage on which the preparations are placed, a preparation stopper provided on the stage and in contact with adjacent edges of the preparations on the stage, and other adjacent edges of the preparations on the stage. At least two levers are provided in contact with each other to suppress the preparation in the longitudinal direction and in the lateral direction, and a mechanism that links the movement of the stage and the suppression of the lever O is provided. A microscope stage in which the slide plate on the stage is fixed and released by the control stopper and the lever. ' (2) The levers 21 and q in +11 have different pressing forces, and are levers with weaker pressing forces that press in either one of the longitudinal and transverse directions, and the 9 rear pressing force is applied. The microscope stage according to claim 1, wherein a 1% image is obtained by pressing the preparation in the other direction with a strong lever. (3) The preparation stopper and lever have rotatable rollers, and the edge S of the preparation
The microscope stage according to claim 8, wherein the microscope stage is pressed. (4) Any one of claims 181 to 3, characterized in that the roller has a shape in which the surface that contacts the preparation forms an acute angle with respect to the stage surface.
The microscope stage described in section. −