JPS5835633B2 - cryogen - Google Patents

Description

Detailed Description of the Invention The present invention provides ammonium nitrate, acidic ammonium sulfate, acidic sodium sulfate, and sodium sulfate (containing water of crystallization).
This relates to a cooling agent that is a mixture of salts that contain a large amount of crystallized water in a water-impermeable, soft synthetic resin package, etc., and one, two, or three other salts that dissolve and react with the crystallized water. The negative heat of dissolution generated during the contact reaction with the seed salts increases the cooling temperature one after another, causing an appropriate effect to increase cooling, making it possible to sustain the cooling reaction over a short or long period of time. It is a cooling agent with excellent chemical performance for the purpose of

At present, there are already on the market simple cryogens in which two types of salts are packaged separately in one packaging bag, and when used, the two types of salts are mixed to cause a cooling reaction. Cryogens do not show sufficiently satisfactory values in terms of time or cooling temperature, and have little commercial value.They are especially useful as emergency cooling treatment agents, such as cold compresses for diseased areas, cold preservation of food and drink, and other emergencies. However, it has not been possible to provide fast-acting and long-lasting cooling for emergency treatment.

The present invention aims to improve and solve the above-mentioned drawbacks of causing chilling due to a chain dissolution reaction, and to provide a chilling agent that has the ability to be used as an emergency cooling method in various fields. .

As a result of various researches, the inventor has determined that the first, second, and third
By the rapid dissolution of the fourth salts into each other, the temperature was further lowered by doubling the generated negative heat of dissolution, and we succeeded in obtaining a strong cold reaction.

Therefore, in order to achieve the above objectives, we conducted various experiments and research on the selection of safe substances that generate cold reactions and the ratio of their combinations.

As a result, by mixing salt crystals that basically generate negative heat of dissolution due to melting, it is not possible to obtain the initial target temperature drop in a mixture of two types that generate cold. I got a little closer to my goal with a mixture of three types of salts.

Although we have reached a cooling temperature drop, we have also succeeded in creating the ideal combination of cold generators due to temperature drop for the first time in the mixed composition of the 4th type of salts, and confirmed its effectiveness as the most excellent cooling agent. did.

That is, a mixed composition of four types of crystalline salts: ■ ammonium nitrate 15-22% ■ acidic ammonium sulfate 13-21% ■ acidic sodium sulfate 15-22% ■ sodium sulfate (contains crystal water) 42-50% results in the most cold reaction. We have arrived at something that has the effect of occurring.

The cooling agent of the present invention differs from the two-salt composition of conventional products in that the cooling reaction is extremely strong, meaning that one type of salt containing crystallization water reacts with two different salts. It generates a negative heat of solution, and at the same time, the third and fourth types of salts dissolve in it, increasing the negative heat of solution, sustaining the cooling reaction, and producing and maintaining an advantageous cooling effect. Compared to conventional products that produce a cooling effect by reacting with two types of salts, sodium salt and ammonium salt, which have crystallization water in the form of crystals, a certain amount of sodium salt that does not contain crystallization water is mixed. It was possible to obtain a cooling agent with a four-component mixture composition that has the effect of causing a strong temperature drop in the interior.

★★ The cooling agent of the present invention can be effectively used in a wide range of general medical applications, such as for treating fever, headaches, sprains, or for temporarily keeping food and drinks cold. Taking into account specific gravity, storage, etc., the weight of the chemicals was set at an optimal amount of about 250 ft, and the combined amount of salts, their cooling effect, temperature, and reaction time were analyzed and observed.

First, acidic sodium sulfate 1, which is basically the first type of salt.
In contrast, temperature drop experiments were carried out using the second type of salt, sodium sulfate (containing water of crystallization), at mixed composition ratios of 2 times, 1.5 times, 1.3 times, 1.2 times, and 1.1 times. As a result, the cooling effect, temperature difference, and reaction time are as shown in Table 1.

As mentioned above, it has been found that a mixture of 1:1 of acidic sodium sulfate to 1.2:2 of sodium sulfate (containing water of crystallization) provides the optimum cooling effect.

Furthermore, attempts were made to increase the amount of acidic sodium sulfate and to strengthen the temperature drop, but the cooling effect did not improve. In order to increase the effect, an experiment was conducted on the addition of ammonium nitrate, which has a strong property of generating negative heat of solution, by adding another third type of salt to the above basic result 1:1.2 composition. The results are shown in Table 2.

That is, ammonium nitrate was used as the third type of salt at 13 to 2
It was confirmed that by adding up to 2%, a negative heat of dissolution close to the objective was generated and a strong cold reaction occurred.

As a result, we further experimented with acidic ammonium sulfate as a reinforcing salt to replace IJium as a cooling agent, and found that it reacted sustainably at the lowest temperature and maintained the ideal cooling effect. The results are shown in Table 3.

Next, one embodiment of the present invention will be described below.

As shown in Table 3, the ideal blending amount that can be maintained for a long time with the highest cooling effect is as follows.

Namely, ammonium nitrate 15-22%, acidic ammonium sulfate 13-21%, acidic sodium sulfate 15-22%.
, sodium sulfate (containing water of crystallization) 42-50%,
If a cooling reaction is caused by thoroughly mixing these, the desired purpose will be achieved.

First, acidic ammonium sulfate 402, sodium sulfate (
Contains crystal water) 96z, acidic sulfuric acid) IJum 40fI
, when ammonium nitrate 50P is mixed, although there are differences in temperature, the average minimum temperature is -9°C, after 1 hour it is -6°C, after 2 hours it is 1°C, and after 3 hours it is 8°C.
℃, and the desired minimum temperature is -8℃ or lower, average of -5℃ after 1 hour, average of 3℃ after 2 hours, and average of 9℃ after 3 hours.
I was able to reach the following.

Also, acidic ammonium sulfate 40f (16%), sodium sulfate (contains crystal water) 110P (44%), acidic sodium sulfate 50P (20%), ammonium nitrate 502 (
20%), the ideal result is a minimum temperature of -9°C, -5°C after 1 hour, 2°C after 2 hours, and 7°C after 3 hours.
It was also possible to obtain the value of

As mentioned above, ammonium nitrate 15-22%, acidic ammonium sulfate 13-21%, acidic sodium sulfate 15-2%
2%, sodium sulfate (contains water of crystallization) 42-50% 4
When mixed and combined with seeds, it produces an ideal cooling effect, so this cooling reaction can be used as an emergency cooling treatment for cold compresses on diseased areas, temporary cooling of food and drinks, and other emergencies. Sufficient fast-acting and first-aid measures, etc.
Since such good results are obtained, a comparison of the chilled reaction temperature and time between the above compounded material and the conventional product (Fig. 1) shows a significant difference.

That is, as shown in Fig. 1, the one that has the effect of a negative heat of solution reaction by combining the conventionally available salt (second type salt) A and the fourth type salt related to the present invention in an appropriate amount (B is the one in Table 3). When comparing 應1 and C with Tsuta 5) in Table 3,
The cooling temperature of the device according to the present invention is low, and it is clearly shown that the cooling effect is much better and improved than that of the conventional device.

Next, a mixture of acidic sodium sulfate, acidic ammonium sulfate and ammonium nitrate related to the present invention,
Sodium sulfate (contains water of crystallization) is separately packaged and mixed together at the time of use, so that the above-mentioned mixture of sodium acidic sulfate, ammonium acidic sulfate, and ammonium nitrate is mixed with sodium sulfate (containing water of crystallization). When a cold reaction occurs, it is safe and can withstand long-term storage without any chemical reaction, and in an emergency, the package can be kneaded to quickly maintain a low temperature. Therefore, it has an extremely large practical effect in emergency cooling treatment, health treatment, etc.

[Brief explanation of the drawing]

FIG. 1 is a diagram showing a comparison of cold reaction temperature and time between a conventionally available product and a product according to the present invention, where A is the conventionally available product and B is the AI according to the present invention shown in Table 3. C is the one in item 5 of Table 3 according to the present invention.

Claims (1)

[Claims] 1. 15-22% ammonium nitrate, 13-21% acidic ammonium sulfate, and 15-22% acidic sodium sulfate.
% and 42-50% sodium sulfate (containing crystal water). 2 The mixture of acidic sodium sulfate, acidic ammonium sulfate and ammonium nitrate and sodium sulfate (containing water of crystallization) are separately packaged and mixed together at the time of use, so that the above-mentioned acidic sodium sulfate, acidic ammonium sulfate and ammonium nitrate are mixed. The cooling agent according to claim 1, characterized in that a cooling reaction is caused by mixing the cooling agent with sodium sulfate (containing water of crystallization).