JPS5775141A - Adsorbent for high molecular weight protein - Google Patents
Adsorbent for high molecular weight proteinInfo
- Publication number
- JPS5775141A JPS5775141A JP55152457A JP15245780A JPS5775141A JP S5775141 A JPS5775141 A JP S5775141A JP 55152457 A JP55152457 A JP 55152457A JP 15245780 A JP15245780 A JP 15245780A JP S5775141 A JPS5775141 A JP S5775141A
- Authority
- JP
- Japan
- Prior art keywords
- porous
- porous body
- adsorbent
- protein
- glass
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Peptides Or Proteins (AREA)
- External Artificial Organs (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
PURPOSE: To make possible the sterilization of an adsorbent for high mol.wt. protein possible and improve the adsorptive performance of conjugated protein, etc. by using a porous body having pore sizs of a specific range for said adsorbent.
CONSTITUTION: Borosilicate glass is subjected to heat treatment, phase separation, acid treatment, etc., whereby a porous body of porous glass or the like of ≥0.5cc/ g pore volume, and 1,000W3,000Å average pore sizes is made. Negative electric charge is applied on the surface of this porous body. Or the surface of the porous body is coated with a hydrophilic polymer. This porous body is formed of porous glass, porous silica, porous alumina, porous ceramic or the like. The adsorbent consisting of such porous body adsorbs and removes protein such as complement, fibrinogen, microfibrin, antigen-antibody complex, etc., or complex with sugar or nucleic acid in blood, blood clot, or body fluid at high rates of adsorption.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55152457A JPS5775141A (en) | 1980-10-29 | 1980-10-29 | Adsorbent for high molecular weight protein |
US06/250,630 US4384954A (en) | 1980-04-16 | 1981-04-03 | Column for adsorption of blood proteins |
GB8111578A GB2075362B (en) | 1980-04-16 | 1981-04-13 | Column for adsorption of blood proteins |
FR8107714A FR2480606B1 (en) | 1980-04-16 | 1981-04-16 | |
DE3115608A DE3115608C2 (en) | 1980-04-16 | 1981-04-16 | Device for the adsorption of blood proteins |
US06/383,137 US4421684A (en) | 1980-04-16 | 1982-05-28 | Column for adsorption of blood proteins |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55152457A JPS5775141A (en) | 1980-10-29 | 1980-10-29 | Adsorbent for high molecular weight protein |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5775141A true JPS5775141A (en) | 1982-05-11 |
Family
ID=15540929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55152457A Pending JPS5775141A (en) | 1980-04-16 | 1980-10-29 | Adsorbent for high molecular weight protein |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5775141A (en) |
-
1980
- 1980-10-29 JP JP55152457A patent/JPS5775141A/en active Pending
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