JPS5756477A - Spiro compound, its preparation and prophylactic and remedy for circulatory disorders - Google Patents

Info

Publication number

JPS5756477A

JPS5756477A JP1129081A JP1129081A JPS5756477A JP S5756477 A JPS5756477 A JP S5756477A JP 1129081 A JP1129081 A JP 1129081A JP 1129081 A JP1129081 A JP 1129081A JP S5756477 A JPS5756477 A JP S5756477A

Authority

JP

Japan

Prior art keywords

compound

remedy

prophylactic

preparation

circulatory disorders

Prior art date

1980-09-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 230000000069 prophylactic effect Effects 0.000 title abstract 2
• 150000003413 spiro compounds Chemical class 0.000 title abstract 2
• GVNVAWHJIKLAGL-UHFFFAOYSA-N 2-(cyclohexen-1-yl)cyclohexan-1-one Chemical compound O=C1CCCCC1C1=CCCCC1 GVNVAWHJIKLAGL-UHFFFAOYSA-N 0.000 abstract 1
• 206010002383 Angina Pectoris Diseases 0.000 abstract 1
• 206010008190 Cerebrovascular accident Diseases 0.000 abstract 1
• 101150065749 Churc1 gene Proteins 0.000 abstract 1
• 206010018364 Glomerulonephritis Diseases 0.000 abstract 1
• 206010061216 Infarction Diseases 0.000 abstract 1
• 102100038239 Protein Churchill Human genes 0.000 abstract 1
• 208000006011 Stroke Diseases 0.000 abstract 1
• AVRWEULSKHQETA-UHFFFAOYSA-N Thiophene-2 Chemical compound S1C=2CCCCCC=2C(C(=O)OC)=C1NC(=O)C1=C(F)C(F)=C(F)C(F)=C1F AVRWEULSKHQETA-UHFFFAOYSA-N 0.000 abstract 1
• 208000007536 Thrombosis Diseases 0.000 abstract 1
• 125000002252 acyl group Chemical group 0.000 abstract 1
• 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
• 125000000217 alkyl group Chemical group 0.000 abstract 1
• 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
• 125000004414 alkyl thio group Chemical group 0.000 abstract 1
• -1 amino, hydroxyl Chemical group 0.000 abstract 1
• 125000005605 benzo group Chemical group 0.000 abstract 1
• 239000008280 blood Substances 0.000 abstract 1
• 210000004369 blood Anatomy 0.000 abstract 1
• 125000005521 carbonamide group Chemical group 0.000 abstract 1
• 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
• 230000002490 cerebral effect Effects 0.000 abstract 1
• 230000015271 coagulation Effects 0.000 abstract 1
• 238000005345 coagulation Methods 0.000 abstract 1
• 150000001875 compounds Chemical class 0.000 abstract 1
• 238000006114 decarboxylation reaction Methods 0.000 abstract 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
• 208000035475 disorder Diseases 0.000 abstract 1
• 230000000694 effects Effects 0.000 abstract 1
• 229910052736 halogen Inorganic materials 0.000 abstract 1
• 125000005843 halogen group Chemical group 0.000 abstract 1
• 230000007574 infarction Effects 0.000 abstract 1
• 230000002401 inhibitory effect Effects 0.000 abstract 1
• 239000000463 material Substances 0.000 abstract 1
• 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
• 208000001297 phlebitis Diseases 0.000 abstract 1
• 229940124530 sulfonamide Drugs 0.000 abstract 1
• 150000003456 sulfonamides Chemical class 0.000 abstract 1
• LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
• 230000001732 thrombotic effect Effects 0.000 abstract 1