JPS5750916A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS5750916A JPS5750916A JP12668780A JP12668780A JPS5750916A JP S5750916 A JPS5750916 A JP S5750916A JP 12668780 A JP12668780 A JP 12668780A JP 12668780 A JP12668780 A JP 12668780A JP S5750916 A JPS5750916 A JP S5750916A
- Authority
- JP
- Japan
- Prior art keywords
- carcinostatic agent
- formula
- suppository
- daily
- injection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
PURPOSE: To provide a low-toxic carcinostatic agent containing a specific dithiol derivative as an active component.
CONSTITUTION: A carcinostatic agent containing the thiol derivative of formula (R1 and R2 are 1W5C alkyl) as an active component. The compound of formula has excellent effect for suppressing the tumor of warm-blooded animals, and consequently, exhibits remarkable effect to elongate the life of the affected animal. It is useful as an carcinostatic agent against various human malignant tumors, such as gastric cancer, hepatic cancer, rectal cancer, leukemia, etc. It can be administered, e.g. in the form of oral drug, suppository, injection, etc. Dose: 1W200mg/kg daily for oral administration or as a suppository, and about 0.1W20mg/kg daily for injection. Some of the compounds of formula are known as agricultural and horticultural fungicides and remedies for hepatic diseases.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12668780A JPS5750916A (en) | 1980-09-12 | 1980-09-12 | Carcinostatic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12668780A JPS5750916A (en) | 1980-09-12 | 1980-09-12 | Carcinostatic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5750916A true JPS5750916A (en) | 1982-03-25 |
JPS6366287B2 JPS6366287B2 (en) | 1988-12-20 |
Family
ID=14941359
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12668780A Granted JPS5750916A (en) | 1980-09-12 | 1980-09-12 | Carcinostatic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5750916A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0134112A2 (en) * | 1983-08-01 | 1985-03-13 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for prophylaxis or treatment of ketosis in livestock |
EP0585728A1 (en) * | 1992-08-29 | 1994-03-09 | Nihon Nohyaku Co., Ltd. | Use of dithiolylidene malonate derivatives for the prevention of metastasis |
AT403434B (en) * | 1992-01-17 | 1998-02-25 | Nihon Nohyaku Co Ltd | TOPICAL COMPOSITION TO ACCELERATE Wounds Healing |
-
1980
- 1980-09-12 JP JP12668780A patent/JPS5750916A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0134112A2 (en) * | 1983-08-01 | 1985-03-13 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for prophylaxis or treatment of ketosis in livestock |
US5001143A (en) * | 1983-08-01 | 1991-03-19 | Nihon Nohyaku Co., Ltd. | Pharmaceutical composition for prophylactic and preventive of ketosis of livestocks |
AT403434B (en) * | 1992-01-17 | 1998-02-25 | Nihon Nohyaku Co Ltd | TOPICAL COMPOSITION TO ACCELERATE Wounds Healing |
EP0585728A1 (en) * | 1992-08-29 | 1994-03-09 | Nihon Nohyaku Co., Ltd. | Use of dithiolylidene malonate derivatives for the prevention of metastasis |
Also Published As
Publication number | Publication date |
---|---|
JPS6366287B2 (en) | 1988-12-20 |
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