JPS5742634A - Latex sensitized with group polysaccharide antibody in streptococcus hemolyticus - Google Patents
Latex sensitized with group polysaccharide antibody in streptococcus hemolyticusInfo
- Publication number
- JPS5742634A JPS5742634A JP11703180A JP11703180A JPS5742634A JP S5742634 A JPS5742634 A JP S5742634A JP 11703180 A JP11703180 A JP 11703180A JP 11703180 A JP11703180 A JP 11703180A JP S5742634 A JPS5742634 A JP S5742634A
- Authority
- JP
- Japan
- Prior art keywords
- latex
- streptococcus hemolyticus
- hemolyticus
- group polysaccharide
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: The titled latex that is made by sensitizing latex with the group polysaccharide antibody against Streptococcus hemolyticus that is prepared by isolating and purifying from the cell antibody of Streptococcus hemolyticus, thus enabling the early diagnosis of infections caused by Streptococcus hemolyticus by the coagulation reaction of reversed passive latex.
CONSTITUTION: The group polysaccharide that is contained in all the strains of Streptococcus hemolyticus is mixed with the cell antibody of ttreptococcus hemolyticus made by immunization to form the precipitant of only the immune complex, which is centrifuged for separation. Then, the precipitant is thoroughly washed to produce pure polysaccharide immune complex. The complex is dissociated to form the group polysaccharide antibody against Streptococcus hemolyticus, which is sensitized to latex particles (preferably polystyrene of 0.01W10μ average particle size and of 0.9W1.4 specifi gravity). The sensitized latex is used to detect the group polysaccharide antibody by the reversed passive latex coagulation reaction. Further addition of glycine, dextran and other additives to the latex is preferred as stabilizers.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11703180A JPS5742634A (en) | 1980-08-27 | 1980-08-27 | Latex sensitized with group polysaccharide antibody in streptococcus hemolyticus |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11703180A JPS5742634A (en) | 1980-08-27 | 1980-08-27 | Latex sensitized with group polysaccharide antibody in streptococcus hemolyticus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5742634A true JPS5742634A (en) | 1982-03-10 |
Family
ID=14701728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11703180A Pending JPS5742634A (en) | 1980-08-27 | 1980-08-27 | Latex sensitized with group polysaccharide antibody in streptococcus hemolyticus |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5742634A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60164250A (en) * | 1984-01-27 | 1985-08-27 | メリデイアン・ダイアグノステイツクス・インコ−ポレ−テツド | Method of detecting beta hemolytic streptococcus antigen |
| JPS60188847A (en) * | 1984-02-27 | 1985-09-26 | ベクトン・デイツキンソン・アンド・カンパニ− | Method of diagnosing streptococcus a |
| US5196239A (en) * | 1988-12-17 | 1993-03-23 | Bayer Aktiengesellschaft | Process for uniform distribution of a free-flowing reaction mixture onto a continuously transported substrate |
-
1980
- 1980-08-27 JP JP11703180A patent/JPS5742634A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60164250A (en) * | 1984-01-27 | 1985-08-27 | メリデイアン・ダイアグノステイツクス・インコ−ポレ−テツド | Method of detecting beta hemolytic streptococcus antigen |
| JPS60188847A (en) * | 1984-02-27 | 1985-09-26 | ベクトン・デイツキンソン・アンド・カンパニ− | Method of diagnosing streptococcus a |
| JPH0315147B2 (en) * | 1984-02-27 | 1991-02-28 | Becton Dickinson Co | |
| US5196239A (en) * | 1988-12-17 | 1993-03-23 | Bayer Aktiengesellschaft | Process for uniform distribution of a free-flowing reaction mixture onto a continuously transported substrate |
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