JPS572237A - Separation of medical component of corbicula through extraction and composition comprising it - Google Patents

Separation of medical component of corbicula through extraction and composition comprising it

Info

Publication number
JPS572237A
JPS572237A JP7575280A JP7575280A JPS572237A JP S572237 A JPS572237 A JP S572237A JP 7575280 A JP7575280 A JP 7575280A JP 7575280 A JP7575280 A JP 7575280A JP S572237 A JPS572237 A JP S572237A
Authority
JP
Japan
Prior art keywords
corbicula
solvent
extracted
water
nonproton
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7575280A
Other languages
Japanese (ja)
Inventor
Junichi Iwamura
Chozo Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INAHATA SANGYO KK
Original Assignee
INAHATA SANGYO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INAHATA SANGYO KK filed Critical INAHATA SANGYO KK
Priority to JP7575280A priority Critical patent/JPS572237A/en
Priority to PCT/JP1981/000127 priority patent/WO1981003489A1/en
Publication of JPS572237A publication Critical patent/JPS572237A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C07C57/12—Straight chain carboxylic acids containing eighteen carbon atoms

Abstract

PURPOSE: To obtain an α, β-unsaturated fatty acid having improving actions on lipid metabolism, by extracting whole parts of corbicula, its fleshy part, or a concentrate of its soaked solution of water prepared by extracting it with water while being hot with a nonproton solvent, followed by removing the solvent.
CONSTITUTION: Whole parts of corbicula or its fleshy part is used directly or after it is cut into pieces it is used. (i) The corbicular is extracted with water in the vicinity of neutrality while it is hot, its soaked solution of water is concentrated, and the concentrate and/or separated fleshy part is extracted with a nonproton solvent, e.g., n-hexane, etc. or (ii) the corbicula is extracted with the nonproton solvent directly. The solvent is removed from the prepared extracted solution, which is purified if necessary, to giva a compound shown by the formula (n is 10, 12, or 14) useful for preventing and remedying liver disorder, having improving effect on lipid metabolism. The purification is carried out using column chromatography and elution is preferably done in the order of kexane, benzene, ethyl ether, and methanol.
COPYRIGHT: (C)1982,JPO&Japio
JP7575280A 1980-06-04 1980-06-04 Separation of medical component of corbicula through extraction and composition comprising it Pending JPS572237A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP7575280A JPS572237A (en) 1980-06-04 1980-06-04 Separation of medical component of corbicula through extraction and composition comprising it
PCT/JP1981/000127 WO1981003489A1 (en) 1980-06-04 1981-06-03 Process for separating medicinal ingredient from corbicula by extraction and composition containing same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7575280A JPS572237A (en) 1980-06-04 1980-06-04 Separation of medical component of corbicula through extraction and composition comprising it

Publications (1)

Publication Number Publication Date
JPS572237A true JPS572237A (en) 1982-01-07

Family

ID=13585292

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7575280A Pending JPS572237A (en) 1980-06-04 1980-06-04 Separation of medical component of corbicula through extraction and composition comprising it

Country Status (2)

Country Link
JP (1) JPS572237A (en)
WO (1) WO1981003489A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5713849U (en) * 1980-06-30 1982-01-23
KR100892063B1 (en) 2008-02-21 2009-04-06 재단법인 강릉과학산업진흥원 The corbicula fluminea extract and a manufacturing process of ones have effict the protecting liver
KR20190027743A (en) 2017-09-07 2019-03-15 르네사스 일렉트로닉스 가부시키가이샤 Motor driving system and motor driving method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5592321A (en) * 1979-01-05 1980-07-12 Nobuko Iritani Antilipemic agent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5592321A (en) * 1979-01-05 1980-07-12 Nobuko Iritani Antilipemic agent

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5713849U (en) * 1980-06-30 1982-01-23
KR100892063B1 (en) 2008-02-21 2009-04-06 재단법인 강릉과학산업진흥원 The corbicula fluminea extract and a manufacturing process of ones have effict the protecting liver
KR20190027743A (en) 2017-09-07 2019-03-15 르네사스 일렉트로닉스 가부시키가이샤 Motor driving system and motor driving method

Also Published As

Publication number Publication date
WO1981003489A1 (en) 1981-12-10

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