JPS57200336A - Erythro-1,2,3-triphenyl-1-pentanone compound, manufacture and tumor therapy containing same - Google Patents

Erythro-1,2,3-triphenyl-1-pentanone compound, manufacture and tumor therapy containing same

Info

Publication number
JPS57200336A
JPS57200336A JP57090457A JP9045782A JPS57200336A JP S57200336 A JPS57200336 A JP S57200336A JP 57090457 A JP57090457 A JP 57090457A JP 9045782 A JP9045782 A JP 9045782A JP S57200336 A JPS57200336 A JP S57200336A
Authority
JP
Japan
Prior art keywords
erythro
triphenyl
formula
group
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57090457A
Other languages
English (en)
Other versions
JPS624382B2 (ja
Inventor
Shitsukukanederu Herumuuto
Reseru Roorando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Deutschland GmbH
Original Assignee
Klinge Pharma GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Pharma GmbH and Co filed Critical Klinge Pharma GmbH and Co
Publication of JPS57200336A publication Critical patent/JPS57200336A/ja
Publication of JPS624382B2 publication Critical patent/JPS624382B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP57090457A 1981-05-27 1982-05-27 Erythro-1,2,3-triphenyl-1-pentanone compound, manufacture and tumor therapy containing same Granted JPS57200336A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3121175A DE3121175A1 (de) 1981-05-27 1981-05-27 Erythro-1,2,3-triphenyl-1-pentanon-derivate sowie verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
JPS57200336A true JPS57200336A (en) 1982-12-08
JPS624382B2 JPS624382B2 (ja) 1987-01-30

Family

ID=6133393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57090457A Granted JPS57200336A (en) 1981-05-27 1982-05-27 Erythro-1,2,3-triphenyl-1-pentanone compound, manufacture and tumor therapy containing same

Country Status (6)

Country Link
US (1) US4764533A (ja)
EP (1) EP0065692B1 (ja)
JP (1) JPS57200336A (ja)
AT (1) ATE10834T1 (ja)
DE (2) DE3121175A1 (ja)
IE (1) IE53576B1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509858A (ja) * 2003-10-21 2007-04-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 新規な選択的エストロゲンレセプターモジュレーターの開発

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554628A (en) * 1994-09-20 1996-09-10 Eli Lilly And Company Method for minimizing the uterothrophic effect of tamoxifen and tamoxifen analogs
US7501441B1 (en) * 1994-09-20 2009-03-10 Eli Lilly And Company Naphthyl compounds, intermediates, processes, compositions, and methods
US5998401A (en) * 1995-02-28 1999-12-07 Eli Lilly And Company Naphthyl compounds, intermediates, compositions, and methods
CA2214929A1 (en) * 1996-09-26 1998-03-26 Charles Willis Lugar, Iii Naphthofluorene compounds, intermediates, compositions and methods
DE19653585A1 (de) * 1996-12-20 1998-06-25 Bayer Ag Colöserfreie, wäßrige, anionische Polyurethandispersionen, ein Verfahren zu ihrer Herstellung und Verwendung
US8236987B2 (en) * 2007-11-09 2012-08-07 The Regents Of The University Of California Selective estrogen receptor modulator compositions and methods for treatment of disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1013907A (en) 1962-09-13 1965-12-22 Ici Ltd Alkene derivatives
US3494934A (en) * 1968-07-15 1970-02-10 Parke Davis & Co 3-phenyl-3-tertiaryamino alkoxyphenyl-propiophenones
DE2646213A1 (de) * 1975-10-28 1977-05-12 Lilly Co Eli Aroylphenylnaphthaline und verfahren zu ihrer herstellung

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007509858A (ja) * 2003-10-21 2007-04-19 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 新規な選択的エストロゲンレセプターモジュレーターの開発
US8263661B2 (en) 2003-10-21 2012-09-11 The Regents Of The University Of California Development of new selective estrogen receptor modulators

Also Published As

Publication number Publication date
EP0065692A1 (de) 1982-12-01
DE3121175A1 (de) 1982-12-16
US4764533A (en) 1988-08-16
DE3261601D1 (en) 1985-01-31
JPS624382B2 (ja) 1987-01-30
IE821264L (en) 1982-11-27
EP0065692B1 (de) 1984-12-19
ATE10834T1 (de) 1985-01-15
IE53576B1 (en) 1988-12-21

Similar Documents

Publication Publication Date Title
WO1992012981A1 (en) Substituted phenyl-1,3 dioxoloquinoline derivatives and their use as antitumor agents
JPS57200336A (en) Erythro-1,2,3-triphenyl-1-pentanone compound, manufacture and tumor therapy containing same
JPS56156275A (en) 1,4-benzodioxane-2-methoxypropanol amines, their manufacture and medicine containing them
MY113803A (en) Fluorophenyl-substituted alkenylcarboxylic acid guanidides, process for their preparation, their use as medicament or diagnostic, and medicament containing them.
ES488446A1 (es) Procedimiento para la preparacion de nuevos derivados indo- licos
MY115805A (en) Substituted benzyloxycarbonylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
ATE48835T1 (de) Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
SE8102220L (sv) Anvendning av substituerade derivat av 4-fenyl-4-oxo-2-butensyra sasom lekemedel
DE3160360D1 (en) 5-subsituted 5,10-dihydro-11h-dibenzo(b,e)(1,4)diazepin-11-ones, process for preparing them and medicaments containing them
DE3571984D1 (en) New substituted benzimidazoles, a process for their preparation and their use for inhibiting gastric acid secretion
ITMI971861A1 (it) Diarilalchilpiperazine attive sulle basse vie urinarie
ATE14424T1 (de) Imidazolidin-derivate, verfahren zu deren herstellung und therapeutische anwendung.
DE3474298D1 (en) Derivatives of 4-phenyl-4-oxo-buten-2-oic acid, their preparation, medicaments and compositions containing them
DK163055C (da) Analogifremgangsmaade til fremstilling af 2-dipropylamino-(5 eller 7)-formylamino-6-hydroxy-1,2,3,4-tetrahydronaphthalen og farmakologisk acceptable syreadditionssalte deraf
ES8201575A1 (es) Procedimiento de obtencion de nuevos 2-aminoetanoles
ES473834A1 (es) Procedimiento de preparacion de nuevos compuestos indolicos.
ES8100282A1 (es) Procedimiento para la obtencion de nuevos derivados de la piperacina metanimina
DE3365933D1 (en) Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds
ES8502689A1 (es) Procedimiento para la preparacion de derivados de benzazepina.
DE3674250D1 (de) Phenylpyrazinderivate, verfahren zu deren herstellung, pharmazeutische zusammensetzung und verwendung.
ES472291A1 (es) Un procedimiento para la preparacion de un indeno
DE3262166D1 (en) A new p-chlorophenoxyacetic acid derivative, its method of preparation and pharmaceutical composition
SE437373B (sv) Forfarande for framstellning av ett aminoalkylfuranderivat med terapeutisk verkan
ES444899A1 (es) Procedimiento para la preparacion de nuevas 2-feniliminoimidazolidinas disustituidas
PT74056A (en) Process for preparing pharmaceutical compositions containing 1--(2-3'-carboxypropionil oxyethyl)-2-methyl-5-nitroimidazole as active therapeutic agent against diseases caused by anaerobic germs