JPS57198096A - Preparation of d(-)-mandelic acid - Google Patents
Preparation of d(-)-mandelic acidInfo
- Publication number
- JPS57198096A JPS57198096A JP8407981A JP8407981A JPS57198096A JP S57198096 A JPS57198096 A JP S57198096A JP 8407981 A JP8407981 A JP 8407981A JP 8407981 A JP8407981 A JP 8407981A JP S57198096 A JPS57198096 A JP S57198096A
- Authority
- JP
- Japan
- Prior art keywords
- genus
- benzoylformic acid
- nocardia
- acid
- leuconostoc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To prepare the titled substance ueful as a raw material of pharmaceuticals, etc., by treating benzoylformic acid with bacteria belonging to Lactobacillus genus, Leuconostoc genus, Streptococcus genus, Nocardia genus, etc.
CONSTITUTION: Benzoylformic acid is treated with bacteria belonging to Lactobacillus genus, Leuconostoc genus, Strephococcus genus, Nocardia genus, Proteus genus, Fusarium genus, etc., e.g. Lactobacillus brevis, Leuconostoc mesenteroides, Nocardia corallina, etc. The treatment is carried out by culturing said bacteria in a medium containing benzoylformic acid, or by reacting benzoylformic acid with the cultured liquid. The reaction is carried out at 3W9pH and 20W40°C to obtain D(-)-mandelic acid converted from benzoylformic acid.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8407981A JPS57198096A (en) | 1981-06-01 | 1981-06-01 | Preparation of d(-)-mandelic acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8407981A JPS57198096A (en) | 1981-06-01 | 1981-06-01 | Preparation of d(-)-mandelic acid |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57198096A true JPS57198096A (en) | 1982-12-04 |
JPH0357752B2 JPH0357752B2 (en) | 1991-09-03 |
Family
ID=13820477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP8407981A Granted JPS57198096A (en) | 1981-06-01 | 1981-06-01 | Preparation of d(-)-mandelic acid |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57198096A (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6332492A (en) * | 1986-07-28 | 1988-02-12 | Agency Of Ind Science & Technol | Production of levorotatory optically active isomer of mandelic acid by enzymatic process |
US4824781A (en) * | 1985-10-15 | 1989-04-25 | Degussa Aktiengesellschaft | Microbiologically produced d(-)-mandelate-dehydrogenase process for obtaining it and its use |
US5296373A (en) * | 1991-06-26 | 1994-03-22 | Nitto Chemical Industry Co., Ltd. | Process for producing R(-)-mandelic acid or a derivative thereof from a mandelonitrile using rhodococcus |
EP0596466A2 (en) * | 1992-11-05 | 1994-05-11 | Tanabe Seiyaku Co., Ltd. | The process for producing D-mandelic acid |
US6777224B2 (en) | 2001-10-24 | 2004-08-17 | Daicel Chemical Industries, Ltd. | Method for producing optically active mandelic acid derivatives |
US7250278B2 (en) | 2002-07-16 | 2007-07-31 | Daicel Chemical Industries, Ltd. | α-keto acid reductase, method for producing the same, and method for producing optically active α-hydroxy acids using the same |
EP2574667A1 (en) | 2011-10-02 | 2013-04-03 | Technische Universität Graz | Enzyme variants |
-
1981
- 1981-06-01 JP JP8407981A patent/JPS57198096A/en active Granted
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4824781A (en) * | 1985-10-15 | 1989-04-25 | Degussa Aktiengesellschaft | Microbiologically produced d(-)-mandelate-dehydrogenase process for obtaining it and its use |
JPS6332492A (en) * | 1986-07-28 | 1988-02-12 | Agency Of Ind Science & Technol | Production of levorotatory optically active isomer of mandelic acid by enzymatic process |
JPH047677B2 (en) * | 1986-07-28 | 1992-02-12 | Kogyo Gijutsuin | |
US5296373A (en) * | 1991-06-26 | 1994-03-22 | Nitto Chemical Industry Co., Ltd. | Process for producing R(-)-mandelic acid or a derivative thereof from a mandelonitrile using rhodococcus |
EP0596466A2 (en) * | 1992-11-05 | 1994-05-11 | Tanabe Seiyaku Co., Ltd. | The process for producing D-mandelic acid |
EP0596466A3 (en) * | 1992-11-05 | 1995-04-05 | Tanabe Seiyaku Co | The process for producing D-mandelic acid. |
US5441888A (en) * | 1992-11-05 | 1995-08-15 | Tanabe Seiyaku Co., Ltd. | Process for producing D-mandelic acid from benzoylformic acid |
US6777224B2 (en) | 2001-10-24 | 2004-08-17 | Daicel Chemical Industries, Ltd. | Method for producing optically active mandelic acid derivatives |
US7250278B2 (en) | 2002-07-16 | 2007-07-31 | Daicel Chemical Industries, Ltd. | α-keto acid reductase, method for producing the same, and method for producing optically active α-hydroxy acids using the same |
EP2574667A1 (en) | 2011-10-02 | 2013-04-03 | Technische Universität Graz | Enzyme variants |
Also Published As
Publication number | Publication date |
---|---|
JPH0357752B2 (en) | 1991-09-03 |
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