JPS57165356A - Active peptide - Google Patents
Active peptideInfo
- Publication number
- JPS57165356A JPS57165356A JP56048379A JP4837981A JPS57165356A JP S57165356 A JPS57165356 A JP S57165356A JP 56048379 A JP56048379 A JP 56048379A JP 4837981 A JP4837981 A JP 4837981A JP S57165356 A JPS57165356 A JP S57165356A
- Authority
- JP
- Japan
- Prior art keywords
- glycine
- compound
- formulai
- hydroxyproline
- proline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A compound of formulaIin which amino acids are arranged in the order of glycine-proline-4-hydroxyproline-glycine-alanine-glycine by the peptide linkages.
USE: A remedy for the circulatory diseases, useful for inhibitory action on treating and preventing particularly arrhythmia, having the cardiac fibrillation and irregular beats particularly arrhythmia, due to potassium, calcium, ouabain, etc., and preferably used as an injection.
PROCESS: A compound of formula II (Z is benzyloxycarbonyl: OBZl is benzyloxy; Gly is glycine; Pro is proline; Hyp is hydroxyproline; Ala is alanine) is reduced to give the compound of formulaI. Alternatively, the cardiac muscle of cattle, a horse or pig is extracted with hot water to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56048379A JPS57165356A (en) | 1981-04-02 | 1981-04-02 | Active peptide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56048379A JPS57165356A (en) | 1981-04-02 | 1981-04-02 | Active peptide |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57165356A true JPS57165356A (en) | 1982-10-12 |
JPS6324520B2 JPS6324520B2 (en) | 1988-05-20 |
Family
ID=12801678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56048379A Granted JPS57165356A (en) | 1981-04-02 | 1981-04-02 | Active peptide |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57165356A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04133144U (en) * | 1991-05-30 | 1992-12-10 | 株式会社クボタ | Transmission structure of grain ejector |
-
1981
- 1981-04-02 JP JP56048379A patent/JPS57165356A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04133144U (en) * | 1991-05-30 | 1992-12-10 | 株式会社クボタ | Transmission structure of grain ejector |
Also Published As
Publication number | Publication date |
---|---|
JPS6324520B2 (en) | 1988-05-20 |
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