JPS57165356A - Active peptide - Google Patents

Active peptide

Info

Publication number
JPS57165356A
JPS57165356A JP56048379A JP4837981A JPS57165356A JP S57165356 A JPS57165356 A JP S57165356A JP 56048379 A JP56048379 A JP 56048379A JP 4837981 A JP4837981 A JP 4837981A JP S57165356 A JPS57165356 A JP S57165356A
Authority
JP
Japan
Prior art keywords
glycine
compound
formulai
hydroxyproline
proline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56048379A
Other languages
Japanese (ja)
Other versions
JPS6324520B2 (en
Inventor
Shinichiro Aonuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOHO SHINYAKU KK
TOUHOU SHINYAKU KK
Original Assignee
TOHO SHINYAKU KK
TOUHOU SHINYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TOHO SHINYAKU KK, TOUHOU SHINYAKU KK filed Critical TOHO SHINYAKU KK
Priority to JP56048379A priority Critical patent/JPS57165356A/en
Publication of JPS57165356A publication Critical patent/JPS57165356A/en
Publication of JPS6324520B2 publication Critical patent/JPS6324520B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

NEW MATERIAL:A compound of formulaIin which amino acids are arranged in the order of glycine-proline-4-hydroxyproline-glycine-alanine-glycine by the peptide linkages.
USE: A remedy for the circulatory diseases, useful for inhibitory action on treating and preventing particularly arrhythmia, having the cardiac fibrillation and irregular beats particularly arrhythmia, due to potassium, calcium, ouabain, etc., and preferably used as an injection.
PROCESS: A compound of formula II (Z is benzyloxycarbonyl: OBZl is benzyloxy; Gly is glycine; Pro is proline; Hyp is hydroxyproline; Ala is alanine) is reduced to give the compound of formulaI. Alternatively, the cardiac muscle of cattle, a horse or pig is extracted with hot water to give the compound of formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP56048379A 1981-04-02 1981-04-02 Active peptide Granted JPS57165356A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP56048379A JPS57165356A (en) 1981-04-02 1981-04-02 Active peptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56048379A JPS57165356A (en) 1981-04-02 1981-04-02 Active peptide

Publications (2)

Publication Number Publication Date
JPS57165356A true JPS57165356A (en) 1982-10-12
JPS6324520B2 JPS6324520B2 (en) 1988-05-20

Family

ID=12801678

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56048379A Granted JPS57165356A (en) 1981-04-02 1981-04-02 Active peptide

Country Status (1)

Country Link
JP (1) JPS57165356A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04133144U (en) * 1991-05-30 1992-12-10 株式会社クボタ Transmission structure of grain ejector

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04133144U (en) * 1991-05-30 1992-12-10 株式会社クボタ Transmission structure of grain ejector

Also Published As

Publication number Publication date
JPS6324520B2 (en) 1988-05-20

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