JPS57158553A - Chromatography device - Google Patents

Chromatography device

Info

Publication number
JPS57158553A
JPS57158553A JP4434681A JP4434681A JPS57158553A JP S57158553 A JPS57158553 A JP S57158553A JP 4434681 A JP4434681 A JP 4434681A JP 4434681 A JP4434681 A JP 4434681A JP S57158553 A JPS57158553 A JP S57158553A
Authority
JP
Japan
Prior art keywords
sample
head
introduction
passages
stationary phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4434681A
Other languages
Japanese (ja)
Other versions
JPS6328265B2 (en
Inventor
Junichiro Otsubo
Isayuki Kobayashi
Yoshiaki Manabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP4434681A priority Critical patent/JPS57158553A/en
Publication of JPS57158553A publication Critical patent/JPS57158553A/en
Publication of JPS6328265B2 publication Critical patent/JPS6328265B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/56—Packing methods or coating methods
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/522—Physical parameters pressure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6021—Adjustable pistons

Abstract

PURPOSE:To introduce a large amt. of sample extremely easily by forming two kinds of passages to a stopcock type introduction head fitted in a column body, and introducing the sample and a moving phase solvent into a stationary phase by discrete operations. CONSTITUTION:A stationary phase 6 is formed by a packing material in a separating column body 1, and a stopcock type introduction head 7 of external operation type is fitted into the upper part of the body 1. The bottom surface of the head 7 is in contact with the top surface of the stationary phase 6, and two kinds of passages 8, 9 for liquid introduction and distribution are formed to the head 7 independently by commonly using an outlet part. The passages 8, 9 are used respectively independently for introduction of a sample and a moving phase solvent. Since these can be used respectively independently in this way, a large amt. of the sample can be introduced without the danger of mixing and diluting of the sample in the moving phase soln. This device is extremely useful for high speed liquid chromatography of an industrial scale.
JP4434681A 1981-03-25 1981-03-25 Chromatography device Granted JPS57158553A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4434681A JPS57158553A (en) 1981-03-25 1981-03-25 Chromatography device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4434681A JPS57158553A (en) 1981-03-25 1981-03-25 Chromatography device

Publications (2)

Publication Number Publication Date
JPS57158553A true JPS57158553A (en) 1982-09-30
JPS6328265B2 JPS6328265B2 (en) 1988-06-07

Family

ID=12688943

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4434681A Granted JPS57158553A (en) 1981-03-25 1981-03-25 Chromatography device

Country Status (1)

Country Link
JP (1) JPS57158553A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01217262A (en) * 1988-02-25 1989-08-30 Tosoh Corp Formation of packing agent packed layer for column for liquid chromatography and a mobile cock type column apparatus used therefor
WO1989012229A1 (en) * 1988-06-03 1989-12-14 Manac Inc. Syringe type column for chromatography
WO1990001165A1 (en) * 1988-07-19 1990-02-08 Manac Inc. Syringe type column for chromatography
US5186839A (en) * 1988-06-03 1993-02-16 Manac Inc. Syringe type column for chromatography
US5266193A (en) * 1988-06-03 1993-11-30 Manac Inc. Syringe type column for chromatography
JP2002257805A (en) * 2001-03-05 2002-09-11 Yamazen Corp Injector to be directly set to liquid chromatography
JP2008241624A (en) * 2007-03-28 2008-10-09 Kurita Water Ind Ltd Chromatography column-use liquid introducing unit, straightening member and chromatography apparatus
WO2015088427A1 (en) * 2013-12-09 2015-06-18 Ge Healthcare Bio-Sciences Ab Piston and process column
WO2015118609A1 (en) * 2014-02-04 2015-08-13 株式会社ワイエムシィ Movable plug-type column and method for using same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0376375U (en) * 1989-11-27 1991-07-31

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01217262A (en) * 1988-02-25 1989-08-30 Tosoh Corp Formation of packing agent packed layer for column for liquid chromatography and a mobile cock type column apparatus used therefor
WO1989012229A1 (en) * 1988-06-03 1989-12-14 Manac Inc. Syringe type column for chromatography
US5186839A (en) * 1988-06-03 1993-02-16 Manac Inc. Syringe type column for chromatography
US5266193A (en) * 1988-06-03 1993-11-30 Manac Inc. Syringe type column for chromatography
WO1990001165A1 (en) * 1988-07-19 1990-02-08 Manac Inc. Syringe type column for chromatography
JP2002257805A (en) * 2001-03-05 2002-09-11 Yamazen Corp Injector to be directly set to liquid chromatography
JP4659237B2 (en) * 2001-03-05 2011-03-30 山善株式会社 Direct injector for liquid chromatography
JP2008241624A (en) * 2007-03-28 2008-10-09 Kurita Water Ind Ltd Chromatography column-use liquid introducing unit, straightening member and chromatography apparatus
WO2015088427A1 (en) * 2013-12-09 2015-06-18 Ge Healthcare Bio-Sciences Ab Piston and process column
US20160305918A1 (en) * 2013-12-09 2016-10-20 Ge Healthcare Bio-Sciences Ab Piston and process column
US10571441B2 (en) 2013-12-09 2020-02-25 Ge Healthcare Bio-Sciences Ab Piston and process column
WO2015118609A1 (en) * 2014-02-04 2015-08-13 株式会社ワイエムシィ Movable plug-type column and method for using same

Also Published As

Publication number Publication date
JPS6328265B2 (en) 1988-06-07

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