JPS57134499A - S-adenosyl-l-methionine-containing composition and its preparation - Google Patents

S-adenosyl-l-methionine-containing composition and its preparation

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Publication number
JPS57134499A
JPS57134499A JP2190881A JP2190881A JPS57134499A JP S57134499 A JPS57134499 A JP S57134499A JP 2190881 A JP2190881 A JP 2190881A JP 2190881 A JP2190881 A JP 2190881A JP S57134499 A JPS57134499 A JP S57134499A
Authority
JP
Japan
Prior art keywords
sulfate
aqueous solution
sam
sulfate radical
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2190881A
Other languages
Japanese (ja)
Inventor
Yuichi Kamisaki
Keiko Hirai
Hajime Kawarada
Kiyoshi Watanabe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP2190881A priority Critical patent/JPS57134499A/en
Publication of JPS57134499A publication Critical patent/JPS57134499A/en
Pending legal-status Critical Current

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Abstract

PURPOSE: The titled composition having improved shelf stability, safety to living body, productivity of industrial scale and economical advantage, comprising S- adenosyl-L-methionine, sulfate radical, and magnesium sulfate in a specific molar ratio.
CONSTITUTION: A white powder composition comprising S-adenosyl-L-methionine- L (referred to as SAM afterward), sulfate radical, and magnesium sulfate in a molar ratio of SAM: sulfate radical: magnesium sulfate of 1:(0.5W1):(2W6), preferably 1:(0.6W0.9):(3W5). An aqueous solution comprising given amounts of the three components is prepared and brought into contact with an organic solvent to be mixed with this aqueous solution, to precipitate the desired composition, or the aqueous solution is vaporized to dryness, to give the desired composition. A sulfate is used as SAM, when the amount of the sulfate radical is more than the given amount based on SAM in the aqueous solution of SAM sulfate, the aqueous solution is brought into contact with an anion exchange resin or magnesium hydroxide is added to it. When the amount of the sulfate radical is less than the given amount, a fixed amount of the sulfate radical is added to the aqueous solution to adjust it to a proper amount of sulfate radical.
COPYRIGHT: (C)1982,JPO&Japio
JP2190881A 1981-02-16 1981-02-16 S-adenosyl-l-methionine-containing composition and its preparation Pending JPS57134499A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2190881A JPS57134499A (en) 1981-02-16 1981-02-16 S-adenosyl-l-methionine-containing composition and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2190881A JPS57134499A (en) 1981-02-16 1981-02-16 S-adenosyl-l-methionine-containing composition and its preparation

Publications (1)

Publication Number Publication Date
JPS57134499A true JPS57134499A (en) 1982-08-19

Family

ID=12068187

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2190881A Pending JPS57134499A (en) 1981-02-16 1981-02-16 S-adenosyl-l-methionine-containing composition and its preparation

Country Status (1)

Country Link
JP (1) JPS57134499A (en)

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