JPS57134481A - Novel 5-(pyridinyl)-benzimidazole compound, manufacture and cardiac stimulant - Google Patents

Novel 5-(pyridinyl)-benzimidazole compound, manufacture and cardiac stimulant

Info

Publication number
JPS57134481A
JPS57134481A JP56215929A JP21592981A JPS57134481A JP S57134481 A JPS57134481 A JP S57134481A JP 56215929 A JP56215929 A JP 56215929A JP 21592981 A JP21592981 A JP 21592981A JP S57134481 A JPS57134481 A JP S57134481A
Authority
JP
Japan
Prior art keywords
pyridinyl
novel
manufacture
benzimidazole compound
cardiac stimulant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP56215929A
Other languages
English (en)
Inventor
Yoofu Retsushiyaa Jiyooji
Shin Boorudebu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of JPS57134481A publication Critical patent/JPS57134481A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP56215929A 1980-12-29 1981-12-29 Novel 5-(pyridinyl)-benzimidazole compound, manufacture and cardiac stimulant Pending JPS57134481A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/220,977 US4335132A (en) 1980-12-29 1980-12-29 5-(Py-Y)-1H-benzimidazol-2-ols and 5-(Py-Y-)-1H-benzimidazole-2-thiols

Publications (1)

Publication Number Publication Date
JPS57134481A true JPS57134481A (en) 1982-08-19

Family

ID=22825829

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56215929A Pending JPS57134481A (en) 1980-12-29 1981-12-29 Novel 5-(pyridinyl)-benzimidazole compound, manufacture and cardiac stimulant

Country Status (13)

Country Link
US (1) US4335132A (ja)
EP (1) EP0055453A3 (ja)
JP (1) JPS57134481A (ja)
KR (1) KR830007627A (ja)
AU (1) AU543328B2 (ja)
CA (1) CA1180714A (ja)
DK (1) DK575081A (ja)
ES (1) ES8300744A1 (ja)
FI (1) FI814168L (ja)
IL (1) IL64674A (ja)
NO (1) NO814348L (ja)
PT (1) PT74213B (ja)
ZA (1) ZA818897B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
LU85298A1 (fr) * 1984-04-11 1985-11-27 Wurth Paul Sa Dispositif d'introduction de quantites dosees de matieres pulverulentes dans un fluide de propulsion pneumatique

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE659364A (ja) * 1964-02-05
US3914310A (en) * 1965-08-06 1975-10-21 Ciba Geigy Corp Phenoxy-substituted ortho-nitroanilines and ortho-phenylenediamines
DE2202204C2 (de) * 1972-01-18 1983-06-01 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von 2-Mercaptobenzimidazol
FR2213305B1 (ja) * 1973-01-08 1978-06-23 Ciba Geigy Ag
US3907822A (en) * 1973-06-11 1975-09-23 Squibb & Sons Inc Anti-inflammatory (2-benzimidazoylthio)alkylamidoximes
US4026936A (en) * 1975-08-07 1977-05-31 Hoffmann-La Roche Inc. Anthelmintic pyridine and thiazole substituted benzimidazole carbamates

Also Published As

Publication number Publication date
IL64674A (en) 1984-11-30
AU7884181A (en) 1982-07-08
FI814168L (fi) 1982-06-30
ZA818897B (en) 1982-11-24
NO814348L (no) 1982-06-30
PT74213B (en) 1983-05-30
EP0055453A2 (en) 1982-07-07
ES508374A0 (es) 1982-11-01
KR830007627A (ko) 1983-11-04
EP0055453A3 (en) 1982-09-01
ES8300744A1 (es) 1982-11-01
DK575081A (da) 1982-06-30
AU543328B2 (en) 1985-04-18
US4335132A (en) 1982-06-15
PT74213A (en) 1982-01-01
CA1180714A (en) 1985-01-08
IL64674A0 (en) 1982-03-31

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