JPS57134410A - Cosmetic - Google Patents
CosmeticInfo
- Publication number
- JPS57134410A JPS57134410A JP2047381A JP2047381A JPS57134410A JP S57134410 A JPS57134410 A JP S57134410A JP 2047381 A JP2047381 A JP 2047381A JP 2047381 A JP2047381 A JP 2047381A JP S57134410 A JPS57134410 A JP S57134410A
- Authority
- JP
- Japan
- Prior art keywords
- action
- formula
- added
- cosmetic
- skin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Cosmetics (AREA)
Abstract
NEW MATERIAL:An N,S-diacylglutathione diester of the formula (R1 is acyl; R2 is alcoholic residue). EXAMPLE:N,S-Dioctanoylglutathione distearyl. USE:Useful as a cosmetic base having the inhibitory action on melanization and decoloring action on melanin pigments, capable of dissolving at a low temperature, exhibiting improved percutaneous absorption with high stability. The formulated cosmetic is rapidly deacylated in a living body on application to the skin, gives a desirable enzymic activating action and inhibitory action on tyrosinase activity, and exhibits preventing effects on the dark skin, liver spots or freckles. PROCESS:Glutathione is mixed with N,N'-dimethylformamide, and triethylamine is added thereto. After adding palmitoyl chloride dropwise thereto, p-toluenesulfonic acid and cetyl alcohol are added thereto, and the resultant mixture is refluxed to give N,S-dipalmitoylglutathione dicetyl in the compound of the formula.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2047381A JPS57134410A (en) | 1981-02-14 | 1981-02-14 | Cosmetic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2047381A JPS57134410A (en) | 1981-02-14 | 1981-02-14 | Cosmetic |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57134410A true JPS57134410A (en) | 1982-08-19 |
Family
ID=12028067
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2047381A Pending JPS57134410A (en) | 1981-02-14 | 1981-02-14 | Cosmetic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57134410A (en) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2608425A1 (en) * | 1986-12-17 | 1988-06-24 | Rofsa Cerd | Cosmetic composition for the selective partial depigmentation of the skin and process for manufacturing it |
US5316767A (en) * | 1990-09-28 | 1994-05-31 | Kyowa Hakko Kogyo Co., Ltd. | Whitening cosmetic composition |
US5407667A (en) * | 1990-02-13 | 1995-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Composition containing inclusion complex of glutathione and a or β-cyclodextrine |
JP2003097678A (en) * | 2001-09-21 | 2003-04-03 | Fuji Heavy Ind Ltd | Lubricating structure of automatic transmission |
WO2004010968A1 (en) * | 2002-07-31 | 2004-02-05 | Yu Ruey J | Non-amphoteric glutathione derivative compositions for topical application |
WO2005063795A1 (en) * | 2003-12-30 | 2005-07-14 | Umberto Benatti | Glutathione derivatives and their uses for the treatment of viral diseases |
JPWO2008015734A1 (en) * | 2006-07-31 | 2009-12-17 | トヨタ自動車株式会社 | Assembly member and assembly method of assembly member |
US8142098B2 (en) | 2006-07-31 | 2012-03-27 | Toyota Jidosha Kabushiki Kaisha | Assembly member and method of manufacturing assembly member |
-
1981
- 1981-02-14 JP JP2047381A patent/JPS57134410A/en active Pending
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2608425A1 (en) * | 1986-12-17 | 1988-06-24 | Rofsa Cerd | Cosmetic composition for the selective partial depigmentation of the skin and process for manufacturing it |
US5407667A (en) * | 1990-02-13 | 1995-04-18 | Kyowa Hakko Kogyo Co., Ltd. | Composition containing inclusion complex of glutathione and a or β-cyclodextrine |
US5316767A (en) * | 1990-09-28 | 1994-05-31 | Kyowa Hakko Kogyo Co., Ltd. | Whitening cosmetic composition |
JP2003097678A (en) * | 2001-09-21 | 2003-04-03 | Fuji Heavy Ind Ltd | Lubricating structure of automatic transmission |
WO2004010968A1 (en) * | 2002-07-31 | 2004-02-05 | Yu Ruey J | Non-amphoteric glutathione derivative compositions for topical application |
WO2005063795A1 (en) * | 2003-12-30 | 2005-07-14 | Umberto Benatti | Glutathione derivatives and their uses for the treatment of viral diseases |
JPWO2008015734A1 (en) * | 2006-07-31 | 2009-12-17 | トヨタ自動車株式会社 | Assembly member and assembly method of assembly member |
US8142098B2 (en) | 2006-07-31 | 2012-03-27 | Toyota Jidosha Kabushiki Kaisha | Assembly member and method of manufacturing assembly member |
US8151431B2 (en) | 2006-07-31 | 2012-04-10 | Toyota Jidosha Kabushiki Kaisha | Assembly member and method of manufacturing assembly member |
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